All ProductsDisplaying Products Alphabetically by Name (A)
| Cat. No. | Product Name / Activity |
|---|---|
| 4431 | A 1070722 |
| Highly potent, selective GSK-3 inhibitor | |
| 3793 | A 1120 |
| High affinity retinol-binding protein 4 (RBP4) ligand | |
| 6409 | A 1210477 |
| Selective, high affinity Mcl-1 inhibitor; proapoptotic | |
| 5730 | A 127722 |
| Highly potent, selective ETA antagonist; orally bioavailable | |
| 6972 | A 1899 |
| Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker | |
| 6167 | A 196 |
| Potent and selective SUV420H1/H2 inhibitor | |
| 2524 | A 205804 |
| Selective inhibitor of E-selectin and ICAM-1 expression | |
| 4228 | A 286982 |
| Potent inhibitor of the LFA-1/ICAM-1 interaction | |
| 6493 | A 317491 sodium salt |
| Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive | |
| 6313 | A 33 |
| Potent and selective PDE4B inhibitor | |
| 4697 | A 331440 dihydrochloride |
| Selective H3 antagonist | |
| 2753 | A 350619 hydrochloride |
| Soluble guanylyl cyclase (sGC) activator | |
| 5163 | A 366 |
| Potent and selective G9a/GLP inhibitor | |
| 6470 | A 410099.1 |
| High affinity XIAP antagonist; active in vivo | |
| 6473 | A 410099.1 amide-PEG2-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry | |
| 6472 | A 410099.1 amide-PEG3-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry | |
| 7220 | A 410099.1 amide-PEG4-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry | |
| 7221 | A 410099.1 amide-PEG5-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry | |
| 6474 | A 410099.1 amide-alkylC4-amine |
| IAP ligand with alkyl linker and terminal amine for onward chemistry | |
| 6471 | A 410099.1, amine |
| Functionalized IAP ligand for PROTACs | |
| 4552 | A 412997 dihydrochloride |
| Selective D4 agonist | |
| 3914 | A 419259 trihydrochloride |
| Inhibitor of Src family kinases | |
| 5781 | A 425619 |
| Potent TRPV1 antagonist | |
| 2972 | A 438079 hydrochloride |
| Competitive P2X7 antagonist | |
| 4483 | A 484954 |
| CaM kinase III (eEF-2 kinase) inhibitor | |
| 6387 | A 485 |
| Potent and selective p300/CBP inhibitor; orally bioavailable | |
| 4341 | A 582941 |
| α7 nAChR partial agonist | |
| 1052 | A 61603 hydrobromide |
| α1A agonist | |
| 1534 | A 68930 hydrochloride |
| Potent and selective D1-like agonist | |
| 6715 | A 71915 |
| Highly potent and competitive NPRA antagonist | |
| 3701 | A 740003 |
| Potent and selective P2X7 antagonist | |
| 3336 | A 769662 |
| Potent AMPK activator | |
| 6712 | A 77-01 |
| Potent inhibitor of TGF-βRI | |
| 1701 | A 77636 hydrochloride |
| Potent and selective D1-like agonist; orally active | |
| 5937 | A 779 |
| Selective Mas receptor (Ang-(1-7) receptor) antagonist | |
| 4319 | A 784168 |
| Potent and selective TRPV1 antagonist | |
| 2976 | A 803467 |
| Selective NaV1.8 channel blocker | |
| 4473 | A 804598 |
| Potent and selective P2X7 antagonist | |
| 2939 | A 83-01 |
| Selective inhibitor of TGF-βRI, ALK4 and ALK7 | |
| 4232 | A 839977 |
| Potent P2X7 antagonist | |
| 4477 | A 844606 |
| Selective α7 nAChR partial agonist | |
| 5017 | A 85380 dihydrochloride |
| High affinity and selective α4β2 nAChR agonist | |
| 4571 | A 867744 |
| Positive allosteric modulator of α7 nAChRs | |
| 4249 | A 887826 |
| Potent voltage-dependent NaV1.8 channel blocker | |
| 3587 | A 922500 |
| Potent DGAT-1 inhibitor | |
| 4845 | A 939572 |
| Potent SCD-1 inhibitor | |
| 3753 | A 943931 dihydrochloride |
| Potent and selective H4 antagonist | |
| 4716 | A 967079 |
| Selective TRPA1 channel blocker | |
| 5766 | A 971432 |
| Potent and selective S1P5 agonist | |
| 3640 | A 987306 |
| Potent and selective H4 antagonist | |
| 2411 | A-71623 |
| Potent and selective CCK1 agonist; suppresses feeding | |
| 5397 | A01 |
| High affinity Smurf1 inhibitor; enhances BMP signaling | |
| 5097 | A12B4C3 |
| Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor | |
| 1234 | A23187, free acid |
| Calcium ionophore | |
| 5802 | A37 |
| ALDH1A1 inhibitor | |
| 5595 | A66 |
| Potent and selective PI 3-kinase p110α inhibitor | |
| 0378 | A-7 hydrochloride |
| Calmodulin antagonist | |
| 6759 | AA 147 |
| ER proteostasis regulator | |
| 3972 | AA 29504 |
| Positive allosteric modulator of GABAA receptors | |
| 1462 | AACOCF3 |
| Phospholipase A2 inhibitor | |
| 1515 | 17-AAG |
| Selective Hsp90 inhibitor | |
| 5462 | AAQ chloride |
| Photoswitchable Kv channel blocker | |
| 5229 | ABP 688 |
| High affinity human mGlu5 antagonist | |
| 5038 | ABT |
| Cytochrome P450 inhibitor; inhibits 20-HETE synthesis | |
| 5079 | ABT 089 dihydrochloride |
| High affinity and selective α4β2 nAChR partial agonist | |
| 6960 | ABT 199 |
| Selective, high affinity Bcl-2 inhibitor; orally bioavailable | |
| 6576 | ABT 594 hydrochloride |
| Selective α4β2 nAChR agonist | |
| 6770 | ABT 639 |
| CaV3.2 and CaV3.1 channel blocker; orally bioavailable | |
| 2372 | ABT 702 hydrochloride |
| Adenosine kinase inhibitor; orally active | |
| 6835 | ABT 737 |
| Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines | |
| 5053 | AC 186 |
| Potent and selective ERβ agonist; neuroprotective | |
| 3419 | AC 187 |
| Potent and selective amylin antagonist | |
| 6766 | AC 1903 |
| Selective TRPC5 inhibitor | |
| 4046 | AC 261066 |
| RARβ2 agonist | |
| 3370 | AC 264613 |
| PAR2 receptor agonist | |
| 6165 | AC 265347 |
| Biased allosteric modulator of calcium-sensing receptor (CaSR) | |
| 5281 | AC 5216 |
| Selective TSPO ligand | |
| 3369 | AC 55541 |
| Potent and selective PAR2 agonist | |
| 2436 | AC 55649 |
| Selective RARβ2 agonist | |
| 5013 | AC 710 |
| Potent and selective PDGFR family inhibitor | |
| 1319 | ACEA |
| Potent and highly selective CB1 agonist | |
| 2728 | ACET |
| Potent kainate antagonist; displays selectivity for GluK1-containing receptors | |
| 4547 | ACHP |
| Selective IKKα and IKKβ inhibitor | |
| 0284 | (1S,3R)-ACPD |
| Group I and group II mGlu agonist; active isomer of (±)-trans-ACPD (Cat. No. 0187) | |
| 0187 | (±)-trans-ACPD |
| Group I and II mGlu agonist | |
| 1111 | ACPT-I |
| Group III mGlu agonist | |
| 1112 | ACPT-II |
| Competitive mGlu receptor antagonist | |
| 3525 | ACSF |
| Artificial cerebrospinal fluid | |
| 4983 | ACT 335827 |
| Potent and selective OX1 antagonist | |
| 5319 | ACT 462206 |
| Potent, dual orexin receptor antagonist | |
| 3492 | ACTH (1-39) |
| Potent endogenous MC2 agonist | |
| 4416 | ADX 10059 hydrochloride |
| Negative allosteric modulator of mGlu5 receptors | |
| 5715 | (±)-ADX 71743 |
| Negative allosteric modulator of mGlu7 receptors; brain penetrant | |
| 5175 | AEBSF |
| Broad spectrum, irreversible inhibitor of serine proteases | |
| 5318 | AEE 788 |
| Potent EGFR and VEGFR inhibitor | |
| 2651 | AEG 3482 |
| Inhibitor of JNK signaling | |
| 1793 | AF 12198 |
| Potent, selective human type I IL-1 receptor antagonist | |
| 6931 | AF 64394 |
| Potent and selective GPR3 inverse agonist | |
| 1105 | AF-DX 116 |
| Selective M2 antagonist | |
| 1345 | AF-DX 384 |
| Potent M2/M4 antagonist | |
| 1276 | AG 1478 hydrochloride |
| Highly potent EGFR-kinase inhibitor | |
| 6242 | AG 205 |
| Progesterone receptor membrane component 1 (Pgrmc1) ligand | |
| 0414 | AG 490 |
| EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor | |
| 1555 | AG 825 |
| Selective ErbB2 inhibitor | |
| 7087 | AGI 5198 |
| Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1) | |
| 1072 | AGN 192403 hydrochloride |
| I1 selective ligand | |
| 5758 | AGN 193109 |
| High affinity pan-RAR antagonist | |
| TB5758-RMU | AGN 193109 New |
| AGN 193109 synthesized to Ancillary Material Grade | |
| 0671 | AH 6809 |
| EP1 and EP2 receptor antagonist | |
| 5256 | AH 7614 |
| Selective FFA4 (GPR120) antagonist | |
| 5145 | AI-3 |
| ARE activator; induces Nrf2-ARE-dependent transcription | |
| 2840 | AICAR |
| AMPK activator | |
| 0904 | AIDA |
| Potent and selective group I mGlu antagonist | |
| 4946 | AIM 100 |
| Potent and selective Ack1 (TNK2) inhibitor | |
| 4754 | AK 7 |
| Selective SIRT2 inhibitor; brain penetrant | |
| 7135 | AKOS 022 New |
| Voltage-dependent anion channel (VDAC) inhibitor | |
| 5985 | AKT Inhibitor IV New |
| Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates | |
| 4753 | AL 8697 |
| Potent and selective p38α inhibitor | |
| 1757 | ALX 5407 hydrochloride |
| Selective non-transportable GlyT1 inhibitor | |
| 5914 | AM 0902 |
| Potent and selective TRPA1 antagonist | |
| 2564 | AM 114 |
| 20S proteasome inhibitor | |
| 3381 | AM 1172 |
| Anandamide uptake inhibitor; also FAAH inhibitor and CB receptor partial agonist | |
| 6495 | AM 12 |
| TRPC5 inhibitor | |
| 6034 | AM 2394 |
| Potent glucokinase activator; orally bioavailable | |
| 1117 | AM 251 |
| Potent CB1 antagonist; also GPR55 agonist | |
| 1115 | AM 281 |
| Potent and selective CB1 inverse agonist | |
| 1116 | AM 404 |
| Anandamide transport inhibitor | |
| 6193 | AM 4113 |
| High affinity and selective CB1 antagonist | |
| 5789 | AM 4668 |
| Potent FFA1 (GPR40) agonist | |
| 0760 | AM 580 |
| Retinoic acid analog; RARα agonist | |
| TB0760-RMU | AM 580 New |
| AM 580 synthesized to Ancillary Material Grade | |
| 1120 | AM 630 |
| Selective CB2 inverse agonist | |
| 5443 | AM 6545 |
| High affinity and selective CB1 antagonist | |
| 3507 | AM 80 |
| RARα agonist; anticancer agent | |
| 6043 | AMBMP hydrochloride |
| Wnt canonical signaling activator; also tubulin polymerization inhibitor | |
| 3299 | AMD 3100 octahydrochloride |
| Highly selective CXCR4 antagonist | |
| 4179 | AMD 3465 hexahydrobromide |
| Potent and selective CXCR4 antagonist | |
| 6166 | AMG 18 hydrochloride |
| Potent and selective IRE1α inhibitor | |
| 4330 | AMG 21629 |
| Potent and selective TRPV1 antagonist | |
| 6874 | AMG 333 |
| Potent and selective TRPM8 antagonist; active in vivo | |
| 4487 | (±)-AMG 487 |
| CXCR3 antagonist; inhibits cell migration and metastasis | |
| 5995 | AMG 517 |
| Potent TRPV1 antagonist | |
| 3920 | AMG 548 |
| Potent and selective p38α inhibitor | |
| 6082 | AMG 837 hemicalcium salt |
| Potent FFA1 (GPR40) partial agonist | |
| 5701 | AMG 853 |
| Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist | |
| 2316 | AMG 9810 |
| Potent and selective TRPV1 competitive antagonist | |
| 5517 | AMG PERK 44 |
| Potent and selective PERK inhibitor; orally bioavailable | |
| 2385 | AMN 082 dihydrochloride |
| Selective mGlu7 agonist | |
| 6086 | AMP PNP |
| Kir6 blocker; non-hydrolyzable AMP analog | |
| 1074 | (RS)-AMPA hydrobromide |
| Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169) | |
| 0169 | (RS)-AMPA |
| Selective AMPA agonist | |
| 0254 | (S)-AMPA |
| Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169) | |
| 1337 | cAMPS-Rp, triethylammonium salt |
| cAMP antagonist | |
| 1333 | cAMPS-Sp, triethylammonium salt |
| Cell-permeable cAMP analog | |
| 0871 | AMT hydrochloride |
| Potent, selective iNOS inhibitor | |
| 3989 | AMTB hydrochloride |
| TRPM8 blocker | |
| 4781 | ANA 12 |
| TrkB receptor antagonist | |
| 3937 | ANR 94 |
| Adenosine A2A antagonist | |
| 6481 | AP 14145 hydrochloride |
| Negative allosteric modulator of KCa2 (SK) channels | |
| 3296 | AP 18 |
| Reversible TRPA1 channel blocker | |
| 6130 | AP 1903 |
| Chemical inducer of protein dimerization; active in vivo | |
| 6297 | AP 20187 |
| Chemical inducer of protein dimerization; active in vivo | |
| 4274 | AP 24534 |
| Potent multi-kinase and pan-Bcr-Abl inhibitor | |
| 5498 | AP 811 |
| High affinity, selective NPR3 antagonist | |
| 6626 | AP C5 |
| Potent and selective PKG2 inhibitor | |
| 5962 | 3-AP |
| Ribonucleotide reductase inhibitor; also an iron chelator | |
| 0125 | DL-AP3 |
| Group I mGlu antagonist; also phosphoserine phosphatase inhibitor | |
| 0102 | D-AP4 |
| Broad spectrum glutamatergic antagonist | |
| 0101 | DL-AP4 |
| Broad spectrum glutamatergic antagonist | |
| 0103 | L-AP4 |
| Selective group III mGlu agonist | |
| 3693 | DL-AP5 Sodium salt |
| Potent and selective NMDA antagonist; sodium salt of DL-AP5 | |
| 0106 | D-AP5 |
| Potent and selective NMDA receptor antagonist; more active form of DL-AP5 | |
| 0105 | DL-AP5 |
| Potent and selective NMDA antagonist | |
| 0107 | L-AP5 |
| Potent and selective NMDA antagonist; less active form of DL-AP5 | |
| 0104 | DL-AP7 |
| Selective NMDA antagonist | |
| 1224 | 2-APB |
| IP3 receptor antagonist. Also TRP channel modulator | |
| 2511 | APC 366 |
| Tryptase inhibitor | |
| 1208 | (2R,4R)-APDC |
| Highly selective group II agonist | |
| 4804 | APETx2 |
| ASIC3 channel blocker | |
| 3897 | API-1 |
| Selective Akt/PKB inhibitor. Antitumor | |
| 2151 | API-2 |
| Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral | |
| 1073 | (RS)-APICA |
| Selective group II mGlu antagonist | |
| 4865 | APY 29 |
| Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity | |
| 2292 | AQ-RA 741 |
| High affinity and selective M2 antagonist | |
| 6163 | AR 420626 |
| FFA3 agonist | |
| 3966 | AR-A 014418 |
| Selective GSK-3 inhibitor | |
| 4890 | AR-C 118925XX |
| Selective and competitive P2Y2 antagonist | |
| 5658 | AR-C 141990 hydrochloride |
| MCT1 inhibitor | |
| 3321 | AR-C 66096 tetrasodium salt |
| Potent and selective P2Y12 antagonist | |
| 5720 | AR-C 69931 tetrasodium salt |
| Highly potent P2Y12 antagonist | |
| 4960 | AR-C155858 |
| MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells | |
| 4335 | AR-M 1000390 hydrochloride |
| Low-internalizing δ agonist | |
| 0928 | ARC 239 dihydrochloride |
| α2B antagonist | |
| 7254 | ARCC 4 |
| Potent and selective androgen receptor PROTAC® | |
| 7255 | ARCC 4 negative control |
| Negative control for ARCC 4 (Cat. No. 7254) | |
| 3319 | ARL 17477 dihydrochloride |
| Selective nNOS inhibitor | |
| 1283 | ARL 67156 trisodium salt |
| NTPDase inhibitor | |
| 7134 | ARN 14494 |
| Potent serine palmitoyltransferase inhibitor | |
| 5862 | ARN 14686 |
| Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe | |
| 5861 | ARN 726 |
| Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe | |
| 2621 | ARP 100 |
| Selective inhibitor of MMP-2 | |
| 2622 | ARP 101 |
| Inhibitor of MMP-2 | |
| 4676 | ARRY 520 trifluoroacetate |
| Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation | |
| 7256 | ARV 771 |
| Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells | |
| 2446 | AS 101 |
| Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release | |
| 4177 | AS 1269574 |
| GPR119 receptor agonist | |
| 4265 | AS 1842856 |
| Potent and selective Foxo1 inhibitor; orally bioavailable | |
| 4927 | AS 1892802 |
| Potent ROCK inhibitor; orally bioavailable | |
| 1968 | AS 19 |
| Potent 5-HT7 agonist | |
| 3718 | AS 1949490 |
| SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor | |
| 5430 | AS 2444697 |
| Potent and selective IRAK4 inhibitor | |
| 3671 | AS 252424 |
| Selective inhibitor of PI 3-kinase γ | |
| 3578 | AS 605240 |
| Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor | |
| 6316 | ASB 14780 |
| Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable | |
| 5308 | ASP 2535 |
| Potent and selective GlyT1 inhibitor | |
| 5310 | ASP 3026 |
| Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor | |
| 5178 | ASP 7663 |
| Selective TRPA1 activator | |
| 6084 | ASP 9521 |
| Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable | |
| 6356 | AT 1 |
| (+)-JQ1 based PROTAC® with selectivity for BRD4 | |
| 3367 | AT 101 |
| Downregulates Bcl-2 and Mcl-1; pro-apoptotic | |
| 3531 | AT 56 |
| L-PGDS inhibitor | |
| 7001 | AT 7867 |
| Potent pan-Akt and PKA inhibitor | |
| 5795 | ATI 2341 |
| CXCR4 allosteric agonist | |
| 6058 | ATN 161 |
| α5β1 integrin receptor antagonist | |
| 3245 | ATP disodium salt |
| P2 agonist | |
| 1107 | ATPA |
| Potent and selective GluK1 kainate agonist | |
| 4080 | ATPγS tetralithium salt |
| Non-selective P2 agonist; analog of ATP (Cat. No. 3245) | |
| 6763 | AVE 1625 |
| Potent and selective CB1 receptor antagonist | |
| 5843 | AX 15836 |
| Potent and selective ERK5 inhibitor | |
| 7034 | AY 254 |
| Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling | |
| 7033 | AY 77 |
| Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling | |
| 1639 | AY 9944 dihydrochloride |
| Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase | |
| 1487 | AY-NH2 |
| Selective PAR4 agonist | |
| 5872 | AZ 10397767 |
| Potent CXCR2 antagonist | |
| 3323 | AZ 10606120 dihydrochloride |
| Potent P2X7 antagonist | |
| 3317 | AZ 11645373 |
| Potent and selective human P2X7 antagonist | |
| 4832 | AZ 12216052 |
| Positive allosteric modulator of mGlu8 receptors | |
| 6870 | AZ 12799734 |
| Potent TGF-βRI inhibitor | |
| 6177 | AZ 13705339 |
| Highly potent PAK1 and PAK2 inhibitor | |
| 6826 | AZ 1729 |
| FFA2 allosteric agonist; displays bias for the Gi signaling pathway | |
| 5232 | AZ 191 |
| Potent DYRK1B inhibitor | |
| 5198 | AZ 20 |
| Potent and selective ATR kinase inhibitor; antitumor | |
| 3994 | AZ 3146 |
| Potent and selective Mps1 kinase inhibitor | |
| 6806 | AZ 3451 |
| Potent negative allosteric modulator of PAR2 receptors | |
| 6330 | AZ 5704 |
| Potent and selective ATM kinase inhibitor; orally bioavailable | |
| 5775 | AZ 6102 |
| Potent TNKS1/2 inhibitor | |
| 4836 | AZ 628 |
| Potent Raf kinase inhibitor | |
| 5632 | AZ Dyrk1B 33 |
| Potent and selective Dyrk1B kinase inhibitor | |
| 5675 | AZ PFKFB3 26 |
| Potent and selective PFKFB3 inhibitor | |
| 5742 | AZ PFKFB3 67 |
| Potent and selective PFKFB3 inhibitor | |
| 6310 | AZD 1208 |
| Potent pan Pim kinase inhibitor | |
| 6085 | AZD 1283 |
| High affinity P2Y12 antagonist | |
| 5617 | AZD 1480 |
| Potent and selective JAK2 inhibitor; antiangiogenic | |
| 5614 | AZD 2066 |
| mGlu5 antagonist; orally bioavailable and brain penetrant | |
| 6541 | AZD 2098 |
| Potent and selective CCR4 antagonist | |
| 6060 | AZD 2461 |
| Potent PARP inhibitor; orally bioavailable | |
| 5615 | AZD 3147 |
| Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable | |
| 4837 | AZD 3988 |
| Potent and selective DGAT-1 inhibitor | |
| 6978 | AZD 5363 |
| Potent pan-AKT inhibitor | |
| 3968 | AZD 5438 |
| Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9 | |
| 5141 | AZD 5582 dihydrochloride |
| Dimeric Smac mimetic; potent IAP inhibitor | |
| 4839 | AZD 6482 |
| Potent and selective PI 3-Kβ inhibitor | |
| 5199 | AZD 7762 hydrochloride |
| Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing | |
| 5613 | AZD 9272 |
| Potent and selective mGlu5 antagonist; brain penetrant | |
| 3963 | AZM 475271 |
| Src tyrosine kinase inhibitor | |
| 5113 | AbK |
| Photo-crosslinking probe; unnatural amino acid | |
| 4148 | Abacavir hemisulfate |
| Reverse transcriptase inhibitor; antiretroviral | |
| 6520 | Abiraterone acetate |
| Potent CYP17A1 inhibitor | |
| 1297 | Abn-CBD |
| Selective GPR55 agonist; neurobehaviorally inactive | |
| 6554 | (+)-Abscisic Acid |
| Endogenous LANCL2 agonist | |
| 7242 | Ac-FLTD-CMK New |
| Potent and selective inhibitor of caspases 1, 5 and 4 | |
| 1846 | Ac2-12 |
| Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation | |
| 1845 | Ac2-26 |
| Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation | |
| 3231 | Ac9-25 |
| Annexin I N-terminal peptide; acts as a FPR1 ligand | |
| 3618 | Acamprosate calcium |
| GABA agonist; also glutamatergic modulator | |
| 2673 | Acarbose |
| Glucosidase α inhibitor (intestinal) | |
| 1706 | Acetaminophen |
| Cyclooxygenase inhibitor; may be selective for COX-3 | |
| 6742 | Acetazolamide |
| Carbonic anhydrase inhibitor | |
| 1930 | N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide |
| Phosphopeptide ligand for src SH2 domain | |
| 1927 | N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu |
| Phosphopeptide ligand for src SH2 domain | |
| 2809 | Acetylcholine chloride |
| Endogenous neurotransmitter | |
| 5619 | N-Acetylcysteine amide |
| Glutathione (GSH) precursor; neuroprotective | |
| 5679 | N-Acetylpuromycin |
| Downregulates SnoN and Ski protein expression; promotes TGF-β signaling | |
| 0357 | N-Acetyltryptamine |
| Substrate for serotonin N-acetyl transferase | |
| 1762 | Acifran |
| Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors | |
| 5092 | Acridine Orange hydrochloride |
| Nucleic acid binding dye | |
| 1229 | Actinomycin D |
| Inhibits RNA polymerase | |
| 2513 | Acyclovir |
| Inhibits viral DNA polymerase; antiherpetic agent | |
| 2852 | Adapalene |
| RARβ and RARγ agonist | |
| 5953 | Adaptaquin |
| HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant | |
| 4202 | Adenine |
| Adenine receptor agonist | |
| 3624 | Adenosine |
| Endogenous adenosine receptor agonist | |
| 3633 | Adenosine 5'-(α,β-methylene)diphosphate sodium salt |
| Ecto-5'-nucleotidase (CD73) inhibitor | |
| 5096 | AdipoRon hydrochloride |
| Orally active AdipoR1 and AdipoR2 agonist; antidiabetic | |
| 6812 | Afatinib dimaleate |
| Potent dual specificity EGFR/HER2 inhibitor; active in vivo | |
| 2799 | ω-Agatoxin IVA |
| CaV2.1 blocker | |
| 2802 | ω-Agatoxin TK |
| CaV2.1 blocker | |
| 1353 | Akt/SKG Substrate Peptide |
| Akt/PKB substrate (synthetic) | |
| 5773 | Akti-1/2 |
| Potent and selective dual Akt1 and 2 inhibitor | |
| 4490 | Alantolactone |
| Antiproliferative; induces activin/Smad3 signaling | |
| 4005 | Alda 1 |
| ALDH2 activator; cardioprotective | |
| 3979 | Alexidine dihydrochloride |
| Selective inhibitor of PTPMT1 | |
| 3305 | Alfuzosin hydrochloride |
| Uroselective α1 antagonist | |
| 5491 | Aliskiren hemifumarate |
| Potent renin inhibitor; antihypertensive | |
| 3653 | Allopregnanolone |
| Positive allosteric modulator of GABAA receptors | |
| 2806 | Alprenolol hydrochloride |
| β antagonist; also 5-HT1A antagonist | |
| 1620 | Alprostadil |
| Prostaglandin. Vasodilator and antiplatelet agent in vivo | |
| 6400 | Alsterpaullone |
| Potent CDK1 and CDK2 inhibitor; also inhibits GSK-3β and Lck | |
| 1809 | Altanserin hydrochloride |
| 5-HT2A receptor antagonist | |
| 1893 | Alytesin |
| Amphibian bombesin-like peptide | |
| 4025 | α-Amanitin |
| Inhibitor of RNA polymerase II | |
| 0388 | Ambenonium dichloride |
| Cholinesterase inhibitor | |
| 5828 | Ambrisentan |
| Selective ETA antagonist | |
| 2404 | Ambroxol hydrochloride |
| Na+ channel blocker | |
| 6655 | Amifostine |
| Cytoprotectant | |
| 0890 | Amiloride hydrochloride |
| Na+ channel blocker; also I2 imidazoline ligand | |
| 7121 | 7-Aminoactinomycin D |
| Fluorescent DNA stain | |
| 0788 | 3-Aminobenzamide |
| PARP inhibitor | |
| 0721 | Aminopotentidine |
| H2 antagonist | |
| 2072 | Aminopurvalanol A |
| Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5 | |
| 0940 | 4-Aminopyridine |
| Non-selective KV channel blocker | |
| 7370 | 3-Aminotyrosine |
| Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors | |
| 4095 | Amiodarone hydrochloride |
| Broad spectrum ion channel blocker; antiarrhythmic | |
| 2132 | Amisulpride |
| Selective D2 and D3 antagonist; atypical antipsychotic | |
| 4456 | Amitriptyline hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist | |
| 4857 | Amlexanox |
| Selective inhibitor of TBK | |
| 2571 | Amlodipine besylate |
| CaV1.x blocker | |
| 2813 | D-Amphetamine sulfate |
| Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist | |
| 6930 | Amphotericin B |
| Forms monovalent ion channels in lipid bilyers; antifungal | |
| 0668 | Amthamine dihydrobromide |
| Highly selective standard H2 agonist | |
| 3418 | Amylin |
| Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors | |
| 6030 | Amylin (rat) |
| Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors | |
| 3391 | Amyloid β-peptide (42-1) (human) |
| Inactive control peptide for amyloid β-peptide (1-42) (Cat. No. 1428) | |
| 7031 | Amyloid β-Peptide (1-37) (human) |
| Amyloid β-protein fragment | |
| 1191 | Amyloid β-Peptide (1-40) (human) |
| Amyloid β-protein fragment | |
| 2424 | Amyloid β-peptide (1-40) (rat) |
| Amyloid β-protein fragment | |
| 1428 | Amyloid β-Peptide (1-42) (human) |
| Predominant amyloid β-protein fragment | |
| 2425 | Amyloid β-peptide (1-42) (rat) |
| Predominant amyloid β-protein fragment | |
| 1938 | Amyloid β-Peptide (1-43) (human) |
| Amyloid β-protein fragment | |
| 1429 | Amyloid β-peptide (25-35) (human) |
| Human amyloid β-protein fragment functionally required for neurotoxicity | |
| 1971 | (+)-Anabasine hydrochloride |
| High affinity nAChR partial agonist | |
| 3084 | Anacardic acid |
| Noncompetitive PCAF/p300 inhibitor | |
| 1339 | Anandamide |
| Endogenous and non-selective CB agonist | |
| 3717 | Anandamide - d4 |
| Deuterated anandamide | |
| 3388 | Anastrozole |
| Potent aromatase (CYP19) inhibitor | |
| 0789 | (±)-Anatoxin A fumarate |
| nAChR agonist | |
| 4626 | Andrographolide |
| Inhibits NFκB; blocks androgen receptor (AR) expression | |
| 1562 | Angiotensin (1-7) |
| Vasorelaxant peptide | |
| 1563 | Angiotensin I (human, mouse, rat) |
| Endogenous precursor to angiotensin II (Cat. No. 1158) | |
| 1158 | Angiotensin II |
| Potent vasoconstrictor peptide | |
| 6159 | 4,9-Anhydrotetrodotoxin |
| Potent and selective Nav1.6 channel blocker | |
| 6076 | Ani 9 |
| Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker | |
| 0867 | Aniracetam |
| Inhibits desensitization; AMPA > kainate | |
| 1290 | Anisomycin |
| JNK, SAPK and p38 activator | |
| 6861 | Anle138b |
| Oligomeric aggregation inhibitor; inhibits prion protein and α-synuclein aggregate formation | |
| 0703 | Anpirtoline hydrochloride |
| Highly potent 5-HT1B agonist; also 5-HT3 antagonist | |
| 1954 | Antagonist G |
| Broad spectrum neuropeptide receptor antagonist | |
| 2778 | Antalarmin hydrochloride |
| CRF1 antagonist | |
| 2071 | Antisauvagine-30 |
| Potent, selective and competitive CRF2 antagonist | |
| 1652 | Apamin |
| KCa2 (SK) channel blocker | |
| 5747 | Apcin |
| Cdc20 inhibitor; inhibits Cdc20-substrate interaction | |
| 2420 | [Pyr1]-Apelin-13 |
| Potent peptide apelin agonist | |
| 3007 | Apelin-17 (human, bovine) |
| Endogenous apelin agonist | |
| 2426 | Apelin-36 (human) |
| Endogenous apelin agonist | |
| 2427 | Apelin-36 (rat, mouse) |
| Endogenous apelin agonist | |
| 5736 | Aphidicolin |
| DNA polymerase α, δ and ε inhibitor | |
| 1227 | Apigenin |
| Protein kinase inhibitor | |
| 7283 | Apilimod dimesylate |
| Potent and selective PIKfyve inhibitor | |
| 4663 | Apocynin |
| NADPH-oxidase inhibitor | |
| 2073 | (R)-(-)-Apomorphine hydrochloride |
| Dopamine agonist; non-subtype-selective | |
| 2098 | Apoptosis Activator 2 |
| Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis | |
| 6486 | Aprepitant |
| Potent long-acting hNK1 antagonist | |
| 4139 | Aprotinin |
| Competitive serine protease inhibitor | |
| 1298 | 2-Arachidonylglycerol |
| Endogenous and non-selective CB agonist; potent GPR55 agonist | |
| 1445 | N-Arachidonylglycine |
| GPR18 agonist; endocannabinoid | |
| 7235 | Arbidol |
| Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral | |
| 1777 | Arctigenin |
| Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation | |
| 2457 | Arcyriaflavin A |
| Potent cdk4 inhibitor; also potently inhibits CaM kinase II; antiviral | |
| 0383 | Arecaidine propargyl ester tosylate |
| Muscarinic agonist | |
| 6219 | Arformoterol tartrate |
| Long-acting β2 agonist (LABA) | |
| 1637 | Argatroban |
| Potent thrombin inhibitor | |
| 0663 | L-Arginine |
| Endogenous substrate for NOS | |
| 5584 | Aripiprazole |
| High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist | |
| 6818 | Artemether |
| Antimalarial; also inhibits neuroinflammation | |
| 2668 | Artemisinin |
| Antimalarial; inhibits P-type ATPase (PfATP6) of P.falciparum | |
| 6827 | Artesunate |
| Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial | |
| 4210 | Ascomycin |
| Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631) | |
| 4055 | L-Ascorbic acid |
| Enhances the generation of iPSCs; increases reprogramming efficiency | |
| 3737 | Asenapine maleate |
| Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent | |
| 4092 | Aspirin |
| Cyclooxygenase inhibitor; NSAID | |
| 3489 | Astemizole |
| Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker | |
| 1606 | Astressin |
| Potent CRF antagonist | |
| 2391 | Astressin 2B |
| Selective CRF2 antagonist | |
| 2937 | Atipamezole hydrochloride |
| Selective α2 antagonist | |
| 4580 | Atiprimod dihydrochloride |
| JAK2 inhibitor | |
| 6332 | Atosiban |
| Potent oxytocin receptor antagonist | |
| 1912 | Atrial natriuretic factor (1-28) (rat) |
| Endogenous peptide regulating blood pressure | |
| 1906 | Atrial natriuretic factor (1-28) (human, porcine) |
| Endogenous peptide regulating blood pressure | |
| 4600 | Auranofin |
| Thioredoxin reductase inhibitor; induces MPT | |
| 1688 | Autocamtide-2-related inhibitory peptide |
| Selective CaM kinase II inhibitor | |
| 5959 | Autocamtide-2-related inhibitory peptide, myristoylated |
| CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide | |
| 6324 | Autophinib |
| Potent VPS34 inhibitor | |
| 6834 | Auxin |
| Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone | |
| 6363 | Avagacestat |
| Highly potent γ-secretase inhibitor; orally bioavailable | |
| 6505 | Avasimibe |
| ACAT inhibitor | |
| 4350 | Axitinib |
| Potent VEGFR-1, -2 and -3 inhibitor | |
| 6868 | 8-Azaadenosine |
| ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor; inhibits leukemia stem cell self-renewal | |
| 3842 | 5-Azacytidine |
| DNA methyltransferase inhibitor | |
| 4099 | Azathioprine |
| Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103) | |
| 6584 | L-Azidohomoalanine hydrochloride |
| Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins | |
| 6585 | L-Azidonorleucine hydrochloride |
| Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins | |
| 4150 | Azidothymidine |
| Selective reverse transcriptase inhibitor; antiretroviral | |
| 4553 | Azilsartan |
| Potent AT1 inverse agonist; antihypertensive | |
| 6318 | Azimilide dihydrochloride |
| Kv11.1 (hERG) channel blocker | |
| 3771 | Azithromycin |
| Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation |
Tocris Products by Catalog Number
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