All Products

Displaying Products Alphabetically by Name (A)

Cat. No. Product Name / Activity
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
3793 A 1120
High affinity retinol-binding protein 4 (RBP4) ligand
5730 A 127722
Highly potent, selective ETA antagonist; orally bioavailable
7661 A 1331852
Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis
6972 A 1899
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
6167 A 196
Potent and selective SUV420H1/H2 inhibitor
2524 A 205804
Selective inhibitor of E-selectin and ICAM-1 expression
4228 A 286982
Potent inhibitor of the LFA-1/ICAM-1 interaction
6493 A 317491 sodium salt
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
6313 A 33
Potent and selective PDE4B inhibitor
5163 A 366
Potent and selective G9a/GLP inhibitor
6470 A 410099.1
High affinity XIAP antagonist; active in vivo
6473 A 410099.1 amide-PEG2-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6472 A 410099.1 amide-PEG3-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
7220 A 410099.1 amide-PEG4-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
7221 A 410099.1 amide-PEG5-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6474 A 410099.1 amide-alkylC4-amine
IAP ligand with alkyl linker and terminal amine for onward chemistry
6471 A 410099.1, amine
Functionalized IAP ligand for PROTACs
4552 A 412997 dihydrochloride
Selective D4 agonist
3914 A 419259 trihydrochloride
Inhibitor of Src family kinases
5781 A 425619
Potent TRPV1 antagonist
2972 A 438079 hydrochloride
Competitive P2X7 antagonist
4483 A 484954
CaM kinase III (eEF-2 kinase) inhibitor
6387 A 485
Potent and selective p300/CBP inhibitor; orally bioavailable
4341 A 582941
α7 nAChR partial agonist
1052 A 61603 hydrobromide
α1A agonist
1534 A 68930 hydrochloride
Potent and selective D1-like agonist
6715 A 71915
Highly potent and competitive NPRA antagonist
3701 A 740003
Potent and selective P2X7 antagonist
3336 A 769662
Potent AMPK activator
6712 A 77-01
Potent inhibitor of TGF-βRI
1701 A 77636 hydrochloride
Potent and selective D1-like agonist; orally active
5937 A 779
Selective Mas receptor (Ang-(1-7) receptor) antagonist
4319 A 784168
Potent and selective TRPV1 antagonist
2976 A 803467
Selective NaV1.8 channel blocker
4473 A 804598
Potent and selective P2X7 antagonist
2939 A 83-01
Selective inhibitor of TGF-βRI, ALK4 and ALK7
TB2939-RMU A 83-01
A 83-01 synthesized to Ancillary Material Grade
5017 A 85380 dihydrochloride
High affinity and selective α4β2 nAChR agonist
4571 A 867744
Positive allosteric modulator of α7 nAChRs
4249 A 887826
Potent voltage-dependent NaV1.8 channel blocker
4845 A 939572
Potent SCD-1 inhibitor
4716 A 967079
Selective TRPA1 channel blocker
5766 A 971432
Potent and selective S1P5 agonist
2411 A-71623
Potent and selective CCK1 agonist; suppresses feeding
5397 A01
High affinity Smurf1 inhibitor; enhances BMP signaling
5097 A12B4C3
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
1234 A23187, free acid
Calcium ionophore
5802 A37
ALDH1A1 inhibitor
5595 A66
Potent and selective PI 3-kinase p110α inhibitor
6759 AA 147
ER proteostasis regulator
1462 AACOCF3
Phospholipase A2 inhibitor
1515 17-AAG
Selective Hsp90 inhibitor
5462 AAQ chloride
Photoswitchable Kv channel blocker
5229 ABP 688
High affinity human mGlu5 antagonist
5079 ABT 089 dihydrochloride
High affinity and selective α4β2 nAChR partial agonist
6960 ABT 199
Selective, high affinity Bcl-2 inhibitor; orally bioavailable
7680 ABT 263
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
6576 ABT 594 hydrochloride
Selective α4β2 nAChR agonist
6770 ABT 639
CaV3.2 and CaV3.1 channel blocker; orally bioavailable
2372 ABT 702 hydrochloride
Adenosine kinase inhibitor; orally active
6835 ABT 737
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
6460 ABX 464
HIV RNA splicing modulator
5053 AC 186
Potent and selective ERβ agonist; neuroprotective
3419 AC 187
Potent and selective amylin antagonist
6766 AC 1903
Selective TRPC5 inhibitor
4046 AC 261066
RARβ2 agonist
3370 AC 264613
PAR2 receptor agonist
6165 AC 265347
Biased allosteric modulator of calcium-sensing receptor (CaSR)
5281 AC 5216
Selective TSPO ligand
3369 AC 55541
Potent and selective PAR2 agonist
5013 AC 710
Potent and selective PDGFR family inhibitor
1319 ACEA
Potent and highly selective CB1 agonist
2728 ACET
Potent kainate antagonist; displays selectivity for GluK1-containing receptors
4547 ACHP
Selective IKKα and IKKβ inhibitor
0284 (1S,3R)-ACPD
Group I and group II mGlu agonist; active isomer of (±)-trans-ACPD (Cat. No. 0187)
0187 (±)-trans-ACPD
Group I and II mGlu agonist
3525 ACSF (Artificial Cerebrospinal Fluid)
Artificial cerebrospinal fluid (ACSF) for electrophysiology; sterile and microfiltered
4983 ACT 335827
Potent and selective OX1 antagonist
5319 ACT 462206
Potent, dual orexin receptor antagonist
3492 ACTH (1-39)
Potent endogenous MC2 agonist
7706 ADU-S100 disodium salt
STING agonist
4416 ADX 10059 hydrochloride
Negative allosteric modulator of mGlu5 receptors
5715 (±)-ADX 71743
Negative allosteric modulator of mGlu7 receptors; brain penetrant
5175 AEBSF
Broad spectrum, irreversible inhibitor of serine proteases
5318 AEE 788
Potent EGFR and VEGFR inhibitor
1793 AF 12198
Potent, selective human type I IL-1 receptor antagonist
6931 AF 64394
Potent and selective GPR3 inverse agonist
1105 AF-DX 116
Selective M2 antagonist
1345 AF-DX 384
Potent M2/M4 antagonist
1276 AG 1478 hydrochloride
Highly potent EGFR-kinase inhibitor
6242 AG 205
Progesterone receptor membrane component 1 (Pgrmc1) ligand
0414 AG 490
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
1555 AG 825
Selective ErbB2 inhibitor
7087 AGI 5198
Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)
1072 AGN 192403 hydrochloride
I1 selective ligand
5758 AGN 193109
High affinity pan-RAR antagonist
TB5758-RMU AGN 193109
AGN 193109 synthesized to Ancillary Material Grade
5256 AH 7614
Selective FFA4 (GPR120) antagonist
2840 AICAR
AMPK activator
0904 AIDA
Potent and selective group I mGlu antagonist
4946 AIM 100
Potent and selective Ack1 (TNK2) inhibitor
4754 AK 7
Selective SIRT2 inhibitor; brain penetrant
7135 AKOS 022
Voltage-dependent anion channel (VDAC) inhibitor
5985 AKT Inhibitor IV
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
4753 AL 8697
Potent and selective p38α inhibitor
1757 ALX 5407 hydrochloride
Selective non-transportable GlyT1 inhibitor
5914 AM 0902
Potent and selective TRPA1 antagonist
1117 AM 251
Potent CB1 antagonist; also GPR55 agonist
1116 AM 404
Anandamide transport inhibitor
6193 AM 4113
High affinity and selective CB1 antagonist
0760 AM 580
Retinoic acid analog; RARα agonist
TB0760-RMU AM 580
AM 580 synthesized to Ancillary Material Grade
1120 AM 630
Selective CB2 inverse agonist
5443 AM 6545
High affinity and selective CB1 antagonist
3507 AM 80
RARα agonist; anticancer agent
6043 AMBMP hydrochloride
Wnt canonical signaling activator; also tubulin polymerization inhibitor
3299 AMD 3100 octahydrochloride
Highly selective CXCR4 antagonist
4179 AMD 3465 hexahydrobromide
Potent and selective CXCR4 antagonist
6166 AMG 18 hydrochloride
Potent and selective IRE1α inhibitor
4330 AMG 21629
Potent and selective TRPV1 antagonist
6874 AMG 333
Potent and selective TRPM8 antagonist; active in vivo
4487 (±)-AMG 487
CXCR3 antagonist; inhibits cell migration and metastasis
7713 AMG 510
Potent and selective KRASG12C inhibitor
5995 AMG 517
Potent TRPV1 antagonist
3920 AMG 548
Potent and selective p38α inhibitor
6082 AMG 837 hemicalcium salt
Potent FFA1 (GPR40) partial agonist
5701 AMG 853
Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist
7865 AMG 900
Potent pan-Aurora kinase inhibitor
2316 AMG 9810
Potent and selective TRPV1 competitive antagonist
5517 AMG PERK 44
Potent and selective PERK inhibitor; orally bioavailable
2385 AMN 082 dihydrochloride
Selective mGlu7 agonist
6086 AMP PNP
Kir6 blocker; non-hydrolyzable AMP analog
1074 (RS)-AMPA hydrobromide
Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169)
0169 (RS)-AMPA
Selective AMPA agonist
0254 (S)-AMPA
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
1337 cAMPS-Rp, triethylammonium salt
cAMP antagonist
1333 cAMPS-Sp, triethylammonium salt
Cell-permeable cAMP analog
0871 AMT hydrochloride
Potent, selective iNOS inhibitor
3989 AMTB hydrochloride
TRPM8 blocker
6923 AMZ 30
Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor
4781 ANA 12
TrkB receptor antagonist
3937 ANR 94
Adenosine A2A antagonist
6481 AP 14145 hydrochloride
Negative allosteric modulator of KCa2 (SK) channels
3296 AP 18
Reversible TRPA1 channel blocker
6207 AP 1867
Selective binding ligand for FKBP12F36V
6130 AP 1903
Chemical inducer of protein dimerization; active in vivo
6297 AP 20187
Chemical inducer of protein dimerization; active in vivo
4274 AP 24534
Potent multi-kinase and pan-Bcr-Abl inhibitor
5498 AP 811
High affinity, selective NPR3 antagonist
6626 AP C5
Potent and selective PKG2 inhibitor
5962 3-AP
Ribonucleotide reductase inhibitor; also an iron chelator
0101 DL-AP4
Broad spectrum glutamatergic antagonist
0103 L-AP4
Selective group III mGlu agonist
3693 DL-AP5 Sodium salt
Potent and selective NMDA antagonist; sodium salt of DL-AP5
0106 D-AP5
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
0105 DL-AP5
Potent and selective NMDA antagonist
0107 L-AP5
Potent and selective NMDA antagonist; less active form of DL-AP5
1224 2-APB
IP3 receptor antagonist. Also TRP channel modulator
2511 APC 366
Tryptase inhibitor
1208 (2R,4R)-APDC
Highly selective group II agonist
4804 APETx2
ASIC3 channel blocker
3897 API-1
Selective Akt/PKB inhibitor. Antitumor
2151 API-2
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
4865 APY 29
Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity
2292 AQ-RA 741
High affinity and selective M2 antagonist
6163 AR 420626
FFA3 agonist
3966 AR-A 014418
Selective GSK-3 inhibitor
4890 AR-C 118925XX
Selective and competitive P2Y2 antagonist
5658 AR-C 141990 hydrochloride
MCT1 inhibitor
3321 AR-C 66096 tetrasodium salt
Potent and selective P2Y12 antagonist
5720 AR-C 69931 tetrasodium salt
Highly potent P2Y12 antagonist
4960 AR-C155858
MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells
4335 AR-M 1000390 hydrochloride
Low-internalizing δ agonist
0928 ARC 239 dihydrochloride
α2B antagonist
7254 ARCC 4
Potent and selective androgen receptor PROTAC®
7255 ARCC 4 negative control
Negative control for ARCC 4 (Cat. No. 7254)
3319 ARL 17477 dihydrochloride
Selective nNOS inhibitor
1283 ARL 67156 trisodium salt
NTPDase inhibitor
7909 ARN 11391
Potentiator of the IP3-gated calcium channel ITPR1
7134 ARN 14494
Potent serine palmitoyltransferase inhibitor
7511 ARN 3236
Potent inhibitor of salt-inducible kinases
2622 ARP 101
Inhibitor of MMP-2
4676 ARRY 520 trifluoroacetate
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
7256 ARV 771
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
7636 AS 1517499
STAT6 inhibitor
4265 AS 1842856
Potent and selective Foxo1 inhibitor; orally bioavailable
1968 AS 19
Potent 5-HT7 agonist
3718 AS 1949490
SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor
5430 AS 2444697
Potent and selective IRAK4 inhibitor
7648 AS 99
Selective ASH1L histone methyltransferase inhibitor
7730 AS2717638
Selective, brain penetrant LPA5 antagonist
6316 ASB 14780
Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable
5308 ASP 2535
Potent and selective GlyT1 inhibitor
5310 ASP 3026
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor
5178 ASP 7663
Selective TRPA1 activator
6356 AT 1
(+)-JQ1 based PROTAC® with selectivity for BRD4
3367 AT 101
Downregulates Bcl-2 and Mcl-1; pro-apoptotic
7001 AT 7867
Potent pan-Akt and PKA inhibitor
5795 ATI 2341
CXCR4 allosteric agonist
6058 ATN 161
α5β1 integrin receptor antagonist
3245 ATP disodium salt
P2 agonist
1107 ATPA
Potent and selective GluK1 kainate agonist
4080 ATPγS tetralithium salt
Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
7831 AUNP 12
Peptide inhibitor of the PD-1 signaling pathway
7699 AUTAC4
Mitochondrial targeting AUTAC Degrader
5843 AX 15836
Potent and selective ERK5 inhibitor
1639 AY 9944 dihydrochloride
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
1487 AY-NH2
Selective PAR4 agonist
5872 AZ 10397767
Potent CXCR2 antagonist
3323 AZ 10606120 dihydrochloride
Potent P2X7 antagonist
3317 AZ 11645373
Potent and selective human P2X7 antagonist
6870 AZ 12799734
Potent TGF-βRI inhibitor
6177 AZ 13705339
Highly potent PAK1 and PAK2 inhibitor
7757 AZ 13824374
Potent and selective ATAD2 bromodomain inhibitor
6826 AZ 1729
FFA2 allosteric agonist; displays bias for the Gi signaling pathway
5232 AZ 191
Potent DYRK1B inhibitor
5198 AZ 20
Potent and selective ATR kinase inhibitor; antitumor
3994 AZ 3146
Potent and selective Mps1 kinase inhibitor
6330 AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable
5775 AZ 6102
Potent TNKS1/2 inhibitor
4836 AZ 628
Potent Raf kinase inhibitor
5632 AZ Dyrk1B 33
Potent and selective Dyrk1B kinase inhibitor
5675 AZ PFKFB3 26
Potent and selective PFKFB3 inhibitor
5742 AZ PFKFB3 67
Potent and selective PFKFB3 inhibitor
7845 AZ1 USP25/28 inhibitor
Selective USP25 and USP28 inhibitor
6310 AZD 1208
Potent pan Pim kinase inhibitor
6085 AZD 1283
High affinity P2Y12 antagonist
5617 AZD 1480
Potent and selective JAK2 inhibitor; antiangiogenic
5614 AZD 2066
mGlu5 antagonist; orally bioavailable and brain penetrant
6541 AZD 2098
Potent and selective CCR4 antagonist
6060 AZD 2461
Potent PARP inhibitor; orally bioavailable
7650 AZD 2858
Highly potent GSK-3 inhibitor; inhibits tau phosphorylation
4837 AZD 3988
Potent and selective DGAT-1 inhibitor
7823 AZD 4547
Potent and selective FGFR inhibitor
7130 AZD 5248
Potent cathepsin C inhibitor
6978 AZD 5363
Potent pan-AKT inhibitor
3968 AZD 5438
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
5141 AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
4839 AZD 6482
Potent and selective PI 3-Kβ inhibitor
7825 AZD 7648
Potent and selective DNA-PK inhibitor; enhances CRISPR-mediated HDR efficiency
5199 AZD 7762 hydrochloride
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing
7840 AZD 8055
Highly potent and selective mTOR inhibitor
5613 AZD 9272
Potent and selective mGlu5 antagonist; brain penetrant
3963 AZM 475271
Src tyrosine kinase inhibitor
5113 AbK
Photo-crosslinking probe; unnatural amino acid
4148 Abacavir hemisulfate
Reverse transcriptase inhibitor; antiretroviral
6520 Abiraterone acetate
Potent CYP17A1 inhibitor
1297 Abn-CBD
Selective GPR55 agonist; neurobehaviorally inactive
7936 Ac-Cys-NHMe
Building block for the lysine acylation using conjugating enzymes (LACE) technique
7242 Ac-FLTD-CMK
Potent and selective inhibitor of caspases 1, 5 and 4
1845 Ac2-26
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
7932 Ac4GalN6yne
Alkyne containing monosaccharide building block; used in BOCTAG
8035 Ac4GalNAlk
Metabolic chemical reporter for studying glycosylation and glycoproteins
7750 Ac4GlcNAlk
Metabolic chemical reporter for studying glycosylation and glycoproteins
7479 Ac4ManNAz
Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe
7553 Ac4ManNDAz
Photo-crosslinking probe for studying glycoproteins and glycolipids
2673 Acarbose
Glucosidase α inhibitor (intestinal)
1706 Acetaminophen
Cyclooxygenase inhibitor; may be selective for COX-3
6742 Acetazolamide
Carbonic anhydrase inhibitor
2809 Acetylcholine chloride
Endogenous neurotransmitter
5619 N-Acetylcysteine amide
Glutathione (GSH) precursor; neuroprotective
5679 N-Acetylpuromycin
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
1762 Acifran
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors
5092 Acridine Orange hydrochloride
Nucleic acid binding dye
1229 Actinomycin D
Inhibits RNA polymerase
2513 Acyclovir
Inhibits viral DNA polymerase; antiherpetic agent
2852 Adapalene
RARβ and RARγ agonist
5953 Adaptaquin
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
7589 Adavosertib
Potent and selective Wee1 inhibitor
4202 Adenine
Adenine receptor agonist
3624 Adenosine
Endogenous adenosine receptor agonist
3633 Adenosine 5'-(α,β-methylene)diphosphate sodium salt
Ecto-5'-nucleotidase (CD73) inhibitor
5096 AdipoRon hydrochloride
Orally active AdipoR1 and AdipoR2 agonist; antidiabetic
6812 Afatinib dimaleate
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
2799 ω-Agatoxin IVA
CaV2.1 blocker
2802 ω-Agatoxin TK
CaV2.1 blocker
5773 Akti-1/2
Potent and selective dual Akt1 and 2 inhibitor
4490 Alantolactone
Antiproliferative; induces activin/Smad3 signaling
4005 Alda 1
ALDH2 activator; cardioprotective
3979 Alexidine dihydrochloride
Selective inhibitor of PTPMT1
5491 Aliskiren hemifumarate
Potent renin inhibitor; antihypertensive
8042 Alkyne-cRGD
Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation
3653 Allopregnanolone
Positive allosteric modulator of GABAA receptors
2806 Alprenolol hydrochloride
β antagonist; also 5-HT1A antagonist
1620 Alprostadil
Prostaglandin. Vasodilator and antiplatelet agent in vivo
1809 Altanserin hydrochloride
5-HT2A receptor antagonist
4025 α-Amanitin
Inhibitor of RNA polymerase II
0388 Ambenonium dichloride
Cholinesterase inhibitor
5828 Ambrisentan
Selective ETA antagonist
0890 Amiloride hydrochloride
Na+ channel blocker; also I2 imidazoline ligand
7678 5-Amino-Thalidomide
Cereblon ligand with amine on C5 for onward chemistry
7121 7-Aminoactinomycin D
Fluorescent DNA stain
2072 Aminopurvalanol A
Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
0940 4-Aminopyridine
Non-selective KV channel blocker
7370 3-Aminotyrosine
Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors
2132 Amisulpride
Selective D2 and D3 antagonist; atypical antipsychotic
4857 Amlexanox
Selective inhibitor of TBK
2571 Amlodipine besylate
CaV1.x blocker
2813 D-Amphetamine sulfate
Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist
6930 Amphotericin B
Forms monovalent ion channels in lipid bilyers; antifungal
0668 Amthamine dihydrobromide
Highly selective standard H2 agonist
3418 Amylin
Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors
1191 Amyloid β-Peptide (1-40) (human)
Amyloid β-protein fragment
1428 Amyloid β-Peptide (1-42) (human)
Predominant amyloid β-protein fragment
2425 Amyloid β-peptide (1-42) (rat)
Predominant amyloid β-protein fragment
1429 Amyloid β-peptide (25-35) (human)
Human amyloid β-protein fragment functionally required for neurotoxicity
1971 (+)-Anabasine hydrochloride
High affinity nAChR partial agonist
3084 Anacardic acid
Noncompetitive PCAF/p300 inhibitor
1339 Anandamide
Endogenous and non-selective CB agonist
3717 Anandamide - d4
Deuterated anandamide
3388 Anastrozole
Potent aromatase (CYP19) inhibitor
0789 (±)-Anatoxin A fumarate
nAChR agonist
1562 Angiotensin (1-7)
Vasorelaxant peptide
1563 Angiotensin I (human, mouse, rat)
Endogenous precursor to angiotensin II (Cat. No. 1158)
1158 Angiotensin II
Potent vasoconstrictor peptide
6159 4,9-Anhydrotetrodotoxin
Potent and selective Nav1.6 channel blocker
6076 Ani 9
Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker
1290 Anisomycin
JNK, SAPK and p38 activator
6861 Anle138b
Oligomeric aggregation inhibitor; inhibits prion protein and α-synuclein aggregate formation
0703 Anpirtoline hydrochloride
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
2778 Antalarmin hydrochloride
CRF1 antagonist
1652 Apamin
KCa2 (SK) channel blocker
5747 Apcin
Cdc20 inhibitor; inhibits Cdc20-substrate interaction
2420 [Pyr1]-Apelin-13
Potent peptide apelin agonist
3007 Apelin-17 (human, bovine)
Endogenous apelin agonist
2426 Apelin-36 (human)
Endogenous apelin agonist
5736 Aphidicolin
DNA polymerase α, δ and ε inhibitor
1227 Apigenin
Protein kinase inhibitor
7283 Apilimod dimesylate
Potent and selective PIKfyve inhibitor
4663 Apocynin
NADPH-oxidase inhibitor
2073 (R)-(-)-Apomorphine hydrochloride
Dopamine agonist; non-subtype-selective
2098 Apoptosis Activator 2
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
6486 Aprepitant
Potent long-acting hNK1 antagonist
4139 Aprotinin
Competitive serine protease inhibitor
1298 2-Arachidonylglycerol
Endogenous and non-selective CB agonist; potent GPR55 agonist
7235 Arbidol
Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral
1777 Arctigenin
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
0383 Arecaidine propargyl ester tosylate
Muscarinic agonist
6219 Arformoterol tartrate
Long-acting β2 agonist (LABA)
1637 Argatroban
Potent thrombin inhibitor
5584 Aripiprazole
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
6818 Artemether
Antimalarial; also inhibits neuroinflammation
6827 Artesunate
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
4055 L-Ascorbic acid
Enhances the generation of iPSCs; increases reprogramming efficiency
TB4055-RMU L-Ascorbic acid
L-Ascorbic acid synthesized to Ancillary Material Grade
3737 Asenapine maleate
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
4092 Aspirin
Cyclooxygenase inhibitor; NSAID
3489 Astemizole
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
1606 Astressin
Potent CRF antagonist
2391 Astressin 2B
Selective CRF2 antagonist
7755 Asunaprevir
Potent hepatitis C virus (HCV) NS3 protease inihibitor
2937 Atipamezole hydrochloride
Selective α2 antagonist
6332 Atosiban
Potent oxytocin receptor antagonist
1912 Atrial natriuretic factor (1-28) (rat)
Endogenous peptide regulating blood pressure
1906 Atrial natriuretic factor (1-28) (human, porcine)
Endogenous peptide regulating blood pressure
1688 Autocamtide-2-related inhibitory peptide
Selective CaM kinase II inhibitor
5959 Autocamtide-2-related inhibitory peptide, myristoylated
CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide
6324 Autophinib
Potent VPS34 inhibitor
6834 Auxin
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
7894 Auxinole
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
6363 Avagacestat
Highly potent γ-secretase inhibitor; orally bioavailable
6505 Avasimibe
ACAT inhibitor
4350 Axitinib
Potent VEGFR-1, -2 and -3 inhibitor
6868 8-Azaadenosine
ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor; inhibits leukemia stem cell self-renewal
3842 5-Azacytidine
DNA methyltransferase inhibitor
7664 3-Azido-7-hydroxycoumarin
Click-reactive fluorescent dye. Suitable for live cell imaging
6584 L-Azidohomoalanine hydrochloride
Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins
6585 L-Azidonorleucine hydrochloride
Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins
4150 Azidothymidine
Selective reverse transcriptase inhibitor; antiretroviral
6318 Azimilide dihydrochloride
Kv11.1 (hERG) channel blocker
3771 Azithromycin
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation

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