All Products

Displaying Products Alphabetically by Name (A)

Cat. No. Product Name / Activity
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
3793 A 1120
High affinity retinol-binding protein 4 (RBP4) ligand
6409 A 1210477
Selective, high affinity Mcl-1 inhibitor; proapoptotic
5730 A 127722
Highly potent, selective ETA antagonist; orally bioavailable
6972 A 1899
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
6167 A 196
Potent and selective SUV420H1/H2 inhibitor
2524 A 205804
Selective inhibitor of E-selectin and ICAM-1 expression
4228 A 286982
Potent inhibitor of the LFA-1/ICAM-1 interaction
6493 A 317491 sodium salt
Selective, high affinity P2X3 and P2X2/3 receptor antagonist; antinociceptive
6313 A 33
Potent and selective PDE4B inhibitor
4697 A 331440 dihydrochloride
Selective H3 antagonist
2753 A 350619 hydrochloride
Soluble guanylyl cyclase (sGC) activator
5163 A 366
Potent and selective G9a/GLP inhibitor
6470 A 410099.1
High affinity XIAP antagonist; active in vivo
6473 A 410099.1 amide-PEG2-amine
A 410099.1 amide-PEG2-amine
6472 A 410099.1 amide-PEG3-amine
A 410099.1 amide-PEG3-amine
6474 A 410099.1 amide-alkylC4-amine
A 410099.1 amide-alkylC4-amine
6471 A 410099.1, amine
Functionalized IAP ligand for PROTACs
4552 A 412997 dihydrochloride
Selective D4 agonist
3914 A 419259 trihydrochloride
Inhibitor of Src family kinases
5781 A 425619
Potent TRPV1 antagonist
2972 A 438079 hydrochloride
Competitive P2X7 antagonist
4483 A 484954
CaM kinase III (eEF-2 kinase) inhibitor
6387 A 485
Potent and selective p300/CBP inhibitor; orally bioavailable
4341 A 582941
α7 nAChR partial agonist
1052 A 61603 hydrobromide
α1A agonist
1534 A 68930 hydrochloride
Potent and selective D1-like agonist
6715 A 71915
Highly potent and competitive NPRA antagonist
3701 A 740003
Potent and selective P2X7 antagonist
3336 A 769662
Potent AMPK activator
6712 A 77-01
Potent inhibitor of TGF-βRI
1701 A 77636 hydrochloride
Potent and selective D1-like agonist; orally active
5937 A 779
Selective Mas receptor (Ang-(1-7) receptor) antagonist
4319 A 784168
Potent and selective TRPV1 antagonist
2976 A 803467
Selective NaV1.8 channel blocker
2341 A 80426 mesylate
High affinity α2 antagonist. Also 5-HT uptake inhibitor
4473 A 804598
Potent and selective P2X7 antagonist
2939 A 83-01
Selective inhibitor of TGF-βRI, ALK4 and ALK7
4232 A 839977
Potent P2X7 antagonist
4477 A 844606
Selective α7 nAChR partial agonist
5017 A 85380 dihydrochloride
High affinity and selective α4β2 nAChR agonist
4571 A 867744
Positive allosteric modulator of α7 nAChRs
4249 A 887826
Potent voltage-dependent NaV1.8 channel blocker
3587 A 922500
Potent DGAT-1 inhibitor
4845 A 939572
Potent SCD-1 inhibitor
3753 A 943931 dihydrochloride
Potent and selective H4 antagonist
4716 A 967079
Selective TRPA1 channel blocker
5766 A 971432
Potent and selective S1P5 agonist
3640 A 987306
Potent and selective H4 antagonist
2411 A-71623
Potent and selective CCK1 agonist; suppresses feeding
5397 A01
High affinity Smurf1 inhibitor; enhances BMP signaling
5097 A12B4C3
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
1234 A23187, free acid
Calcium ionophore
5802 A37
ALDH1A1 inhibitor
5595 A66
Potent and selective PI 3-kinase p110α inhibitor
0378 A-7 hydrochloride
Calmodulin antagonist
6759 AA 147
ER proteostasis regulator
3025 AA 2414
Thromboxane A2 (TP) receptor antagonist
3972 AA 29504
Positive allosteric modulator of GABAA receptors
1462 AACOCF3
Phospholipase A2 inhibitor
1515 17-AAG
Selective Hsp90 inhibitor
5462 AAQ chloride
Photoswitchable Kv channel blocker
5229 ABP 688
High affinity human mGlu5 antagonist
5038 ABT
Cytochrome P450 inhibitor; inhibits 20-HETE synthesis
5079 ABT 089 dihydrochloride
High affinity and selective α4β2 nAChR partial agonist
6960 ABT 199
Selective, high affinity Bcl-2 inhibitor; orally bioavailable
6576 ABT 594 hydrochloride
Selective α4β2 nAChR agonist
6770 ABT 639
CaV3.2 and CaV3.1 channel blocker; orally bioavailable
2372 ABT 702 hydrochloride
Adenosine kinase inhibitor; orally active
2214 ABT 724 trihydrochloride
Potent and selective D4 partial agonist; proerectile
6835 ABT 737
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
4138 ABT 751
Inhibitor of microtubule polymerization; antimitotic and antitumor
5053 AC 186
Potent and selective ERβ agonist; neuroprotective
3419 AC 187
Potent and selective amylin antagonist
6766 AC 1903
Selective TRPC5 blocker
6550 AC 253
Amylin (AMY3) antagonist
4046 AC 261066
RARβ2 agonist
3370 AC 264613
PAR2 receptor agonist
6165 AC 265347
Biased allosteric modulator of calcium-sensing receptor (CaSR)
5464 AC 4
Photoswitchable TRPV1 channel blocker
3043 AC 45594
SF-1 inverse agonist
5281 AC 5216
Selective TSPO ligand
3369 AC 55541
Potent and selective PAR2 agonist
2436 AC 55649
Selective RARβ2 agonist
5013 AC 710
Potent and selective PDGFR family inhibitor
2484 (±)-AC 7954 hydrochloride
Non-peptide UT receptor agonist
0963 9-AC
Chloride transport inhibitor
0258 ACBC
NMDA antagonist; acts at glycine site
0271 cis-ACBD
Potent, selective L-glutamate uptake inhibitor
2254 ACDPP hydrochloride
Selective mGlu5 antagonist
1319 ACEA
Potent and highly selective CB1 agonist
5879 ACES
Zwitterionic buffer
2728 ACET
Potent kainate antagonist; displays selectivity for GluK1-containing receptors
4547 ACHP
Selective IKKα and IKKβ inhibitor
0284 (1S,3R)-ACPD
Group I and group II mGlu agonist; active isomer of (±)-trans-ACPD (Cat. No. 0187)
0186 cis-ACPD
Potent NMDA agonist; also group II mGluR agonist
0187 (±)-trans-ACPD
Group I and II mGlu agonist
1111 ACPT-I
Group III mGlu agonist
1112 ACPT-II
Competitive mGlu receptor antagonist
3525 ACSF
Artificial cerebrospinal fluid
4983 ACT 335827
Potent and selective OX1 antagonist
5319 ACT 462206
Potent, dual orexin receptor antagonist
3492 ACTH (1-39)
Potent endogenous MC2 agonist
6840 AD 01
FKBPL (FK506-binding protein like)-based peptide; inhibits breast cancer stem cell self-renewal; also antiangiogenic
4812 ADWX 1
Potent and selective KV1.3 channel blocker
4416 ADX 10059 hydrochloride
Negative allosteric modulator of mGlu5 receptors
5715 (±)-ADX 71743
Negative allosteric modulator of mGlu7 receptors; brain penetrant
5175 AEBSF
Broad spectrum, irreversible inhibitor of serine proteases
5318 AEE 788
Potent EGFR and VEGFR inhibitor
2651 AEG 3482
Inhibitor of JNK signaling
5330 AEG 40730 dihydrochloride
IAP antagonist; induces apoptosis
1793 AF 12198
Potent, selective human type I IL-1 receptor antagonist
6931 AF 64394
Potent and selective GPR3 inverse agonist
1105 AF-DX 116
Selective M2 antagonist
1345 AF-DX 384
Potent M2/M4 antagonist
2730 AG 045572
Selective GnRH receptor antagonist
1276 AG 1478 hydrochloride
Highly potent EGFR-kinase inhibitor
0493 AG 18
EGFR/PDGFR-kinase inhibitor
6242 AG 205
Progesterone receptor membrane component 1 (Pgrmc1) ligand
0414 AG 490
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
0619 AG 494
Potent EGFR-kinase inhibitor
0618 AG 555
Potent EGFR-kinase inhibitor
0616 AG 556
EGFR-kinase inhibitor
1555 AG 825
Selective ErbB2 inhibitor
2617 AG 879
TrkA inhibitor
0497 AG 99
EGFR-kinase inhibitor
3233 AGK 2
Selective SIRT2 inhibitor
1072 AGN 192403 hydrochloride
I1 selective ligand
5758 AGN 193109
High affinity pan-RAR antagonist
0998 AH 11110 hydrochloride
Subtype-selective α1B ligand
0671 AH 6809
EP1 and EP2 receptor antagonist
5256 AH 7614
Selective FFA4 (GPR120) antagonist
5145 AI-3
ARE activator; induces Nrf2-ARE-dependent transcription
2840 AICAR
AMPK activator
0904 AIDA
Potent and selective group I mGlu antagonist
4946 AIM 100
Potent and selective Ack1 (TNK2) inhibitor
0678 (+)-AJ 76 hydrochloride
Antagonist; preferential action at D2-like autoreceptors
4754 AK 7
Selective SIRT2 inhibitor; brain penetrant
2422 AKTide-2T
Akt/PKB substrate (synthetic)
4753 AL 8697
Potent and selective p38α inhibitor
1757 ALX 5407 hydrochloride
Selective non-transportable GlyT1 inhibitor
5914 AM 0902
Potent and selective TRPA1 antagonist
2564 AM 114
20S proteasome inhibitor
3381 AM 1172
Anandamide uptake inhibitor; also FAAH inhibitor and CB receptor partial agonist
6495 AM 12
TRPC5 inhibitor
6034 AM 2394
Potent glucokinase activator; orally bioavailable
1117 AM 251
Potent CB1 antagonist; also GPR55 agonist
1115 AM 281
Potent and selective CB1 inverse agonist
1116 AM 404
Anandamide transport inhibitor
6193 AM 4113
High affinity and selective CB1 antagonist
5789 AM 4668
Potent FFA1 (GPR40) agonist
0760 AM 580
Retinoic acid analog; RARα agonist
1120 AM 630
Selective CB2 inverse agonist
5443 AM 6545
High affinity and selective CB1 antagonist
3507 AM 80
RARα agonist; anticancer agent
5211 AM-TS23
DNA polymerase λ and β inhibitor
6043 AMBMP hydrochloride
Wnt canonical signaling activator; also tubulin polymerization inhibitor
3299 AMD 3100 octahydrochloride
Highly selective CXCR4 antagonist
4179 AMD 3465 hexahydrobromide
Potent and selective CXCR4 antagonist
6166 AMG 18 hydrochloride
Potent and selective IRE1α inhibitor
4330 AMG 21629
Potent and selective TRPV1 antagonist
6874 AMG 333
Potent and selective TRPM8 antagonist; active in vivo
4487 (±)-AMG 487
CXCR3 antagonist; inhibits cell migration and metastasis
5995 AMG 517
Potent TRPV1 antagonist
3920 AMG 548
Potent and selective p38α inhibitor
6082 AMG 837 hemicalcium salt
Potent FFA1 (GPR40) partial agonist
5701 AMG 853
Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist
2316 AMG 9810
Potent and selective, competitive antagonist of TRPV1
5517 AMG PERK 44
Potent and selective PERK inhibitor; orally bioavailable
0524 AMI-193
D2-like antagonist; also selective 5-HT2 antagonist
2385 AMN 082 dihydrochloride
Selective mGlu7 agonist
6086 AMP PNP
Kir6 blocker; non-hydrolyzable AMP analog
1074 (RS)-AMPA hydrobromide
Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169)
0253 (R)-AMPA
Inactive isomer of (RS)-AMPA (Cat. No. 0169)
0169 (RS)-AMPA
Selective AMPA agonist
0254 (S)-AMPA
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
1337 cAMPS-Rp, triethylammonium salt
cAMP antagonist
1333 cAMPS-Sp, triethylammonium salt
Cell-permeable cAMP analog
0871 AMT hydrochloride
Potent, selective iNOS inhibitor
3989 AMTB hydrochloride
TRPM8 blocker
4781 ANA 12
TrkB receptor antagonist
5074 ANQ 11125
Selective motilin receptor antagonist
3937 ANR 94
Adenosine A2A antagonist
6481 AP 14145 hydrochloride
KCa2 channel negative allosteric modulator
3296 AP 18
Reversible TRPA1 channel blocker
4274 AP 24534
Potent multi-kinase and pan-Bcr-Abl inhibitor
5498 AP 811
High affinity, selective NPR3 antagonist
6626 AP C5
Potent and selective PKG2 inhibitor
5962 3-AP
Ribonucleotide reductase inhibitor; also an iron chelator
0125 DL-AP3
Group I mGlu antagonist; also phosphoserine phosphatase inhibitor
3699 DL-AP4 Sodium salt
Broad spectrum glutamatergic antagonist; sodium salt of DL-AP4 (Cat. No. 0101)
0102 D-AP4
Broad spectrum glutamatergic antagonist
0101 DL-AP4
Broad spectrum glutamatergic antagonist
0103 L-AP4
Selective group III mGlu agonist
3693 DL-AP5 Sodium salt
Potent and selective NMDA antagonist; sodium salt of DL-AP5
0106 D-AP5
Potent and selective NMDA antagonist; more active form of DL-AP5
0105 DL-AP5
Potent and selective NMDA antagonist
0107 L-AP5
Potent and selective NMDA antagonist; less active form of DL-AP5
0341 L-AP6
Selective agonist of the 'quis' effect
0104 DL-AP7
Selective NMDA antagonist
1224 2-APB
IP3 receptor antagonist. Also TRP channel modulator
2511 APC 366
Tryptase inhibitor
1208 (2R,4R)-APDC
Highly selective group II agonist
4804 APETx2
ASIC3 channel blocker
3897 API-1
Selective Akt/PKB inhibitor. Antitumor
2151 API-2
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
1073 (RS)-APICA
Selective group II mGlu antagonist
4865 APY 29
Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity
3704 APcK 110
KIT inhibitor
2292 AQ-RA 741
High affinity and selective M2 antagonist
0666 3-AQC
5-HT3 antagonist
6163 AR 420626
FFA3 agonist
3966 AR-A 014418
Selective GSK-3 inhibitor
3969 AR-C 102222
Selective iNOS inhibitor
4890 AR-C 118925XX
Selective and competitive P2Y2 antagonist
5658 AR-C 141990 hydrochloride
MCT1 inhibitor
3321 AR-C 66096 tetrasodium salt
Potent and selective P2Y12 antagonist
5720 AR-C 69931 tetrasodium salt
Highly potent P2Y12 antagonist
4960 AR-C155858
MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells
4335 AR-M 1000390 hydrochloride
Low-internalizing δ agonist
0928 ARC 239 dihydrochloride
α2B antagonist
3319 ARL 17477 dihydrochloride
Selective nNOS inhibitor
1283 ARL 67156 trisodium salt
NTPDase inhibitor
5862 ARN 14686
Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe
5861 ARN 726
Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe
2621 ARP 100
Selective inhibitor of MMP-2
2622 ARP 101
Inhibitor of MMP-2
4676 ARRY 520 trifluoroacetate
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
2446 AS 101
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release
4177 AS 1269574
GPR119 receptor agonist
4265 AS 1842856
Potent and selective Foxo1 inhibitor; orally bioavailable
4927 AS 1892802
Potent ROCK inhibitor; orally bioavailable
1968 AS 19
Potent 5-HT7 agonist
3718 AS 1949490
SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor
5035 AS 2034178
Selective FFA1 (GPR40) agonist
5430 AS 2444697
Potent and selective IRAK4 inhibitor
3671 AS 252424
Selective inhibitor of PI 3-kinase γ
3578 AS 605240
Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor
6044 AS 8351
Induces reprogramming of fibroblasts into functional cardiomyocytes
5308 ASP 2535
Potent and selective GlyT1 inhibitor
5310 ASP 3026
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor
5178 ASP 7663
Selective TRPA1 activator
6084 ASP 9521
Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable
6356 AT 1
(+)-JQ1 based PROTAC with selectivity for BRD4
3367 AT 101
Downregulates Bcl-2 and Mcl-1; pro-apoptotic
4468 AT 1015
Long-acting 5-HT2A antagonist
3531 AT 56
L-PGDS inhibitor
3346 ATC 0175 hydrochloride
MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist
5795 ATI 2341
CXCR4 allosteric agonist
6058 ATN 161
α5β1 integrin receptor antagonist
3245 ATP disodium salt
P2 agonist
1107 ATPA
Potent and selective GluK1 kainate agonist
4080 ATPγS tetralithium salt
Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
4397 AV 412
Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases
6763 AVE 1625
Potent and selective CB1 receptor antagonist
3126 d[Cha4]-AVP
Potent and selective human V1B agonist
5843 AX 15836
Potent and selective ERK5 inhibitor
1639 AY 9944 dihydrochloride
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase
1487 AY-NH2
Selective PAR4 agonist
5872 AZ 10397767
Potent CXCR2 antagonist
3323 AZ 10606120 dihydrochloride
Potent P2X7 receptor antagonist
3317 AZ 11645373
Potent and selective human P2X7 antagonist
4838 AZ 12080282 dihydrochloride
Inhibitor of Hedgehog (Hh) signaling
4832 AZ 12216052
Positive allosteric modulator of mGlu8 receptors
6870 AZ 12799734
Potent TGF-βRI inhibitor
6177 AZ 13705339
Highly potent PAK1 and PAK2 inhibitor
6826 AZ 1729
FFA2 allosteric agonist; displays bias for the Gi signaling pathway
5232 AZ 191
Potent DYRK1B inhibitor
5198 AZ 20
Potent and selective ATR kinase inhibitor; antitumor
3994 AZ 3146
Potent and selective Mps1 kinase inhibitor
6806 AZ 3451
Potent negative allosteric modulator of PAR2 receptors
6330 AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable
5775 AZ 6102
Potent TNKS1/2 inhibitor
4836 AZ 628
Potent Raf kinase inhibitor
5632 AZ Dyrk1B 33
Potent and selective Dyrk1B kinase inhibitor
5675 AZ PFKFB3 26
Potent and selective PFKFB3 inhibitor
5742 AZ PFKFB3 67
Potent and selective PFKFB3 inhibitor
6310 AZD 1208
Potent pan Pim kinase inhibitor
6085 AZD 1283
High affinity P2Y12 antagonist
5617 AZD 1480
Potent and selective JAK2 inhibitor; antiangiogenic
5614 AZD 2066
mGlu5 antagonist; orally bioavailable and brain penetrant
6541 AZD 2098
Potent and selective CCR4 antagonist
6060 AZD 2461
Potent PARP inhibitor; orally bioavailable
5615 AZD 3147
Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable
4837 AZD 3988
Potent and selective DGAT-1 inhibitor
6978 AZD 5363
Potent pan-AKT inhibitor
3968 AZD 5438
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
5141 AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
4839 AZD 6482
Potent and selective PI 3-Kβ inhibitor
5199 AZD 7762 hydrochloride
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing
5613 AZD 9272
Potent and selective mGlu5 antagonist; brain penetrant
3963 AZM 475271
Src tyrosine kinase inhibitor
5113 AbK
Photo-crosslinking probe; unnatural amino acid
4148 Abacavir hemisulfate
Reverse transcriptase inhibitor; antiretroviral
6520 Abiraterone acetate
Potent CYP17A1 inhibitor
1297 Abn-CBD
Selective GPR55 agonist; neurobehaviorally inactive
6554 (+)-Abscisic Acid
Endogenous LANCL2 agonist
1846 Ac2-12
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
1845 Ac2-26
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation
3231 Ac9-25
Annexin I N-terminal peptide; acts as a FPR1 ligand
3618 Acamprosate calcium
GABA agonist; also glutamatergic modulator
2673 Acarbose
Glucosidase α inhibitor (intestinal)
6006 Acein
High affinity angiotensin-converting enzyme (ACE) ligand
3069 Acephate
Anticholinesterase insecticide
1706 Acetaminophen
Cyclooxygenase inhibitor; may be selective for COX-3
6742 Acetazolamide
Carbonic anhydrase inhibitor
5852 Acetyl Pepstatin
High affinity aspartic protease inhibitor; inhibits HIV-1/2 proteinases
1930 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
Phosphopeptide ligand for src SH2 domain
1927 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
Phosphopeptide ligand for src SH2 domain
0355 (±)-Acetylcarnitine chloride
Intermediate in lipid metabolism
2809 Acetylcholine chloride
Endogenous neurotransmitter
5619 N-Acetylcysteine amide
Glutathione (GSH) precursor; neuroprotective
0352 4-Acetyl-1,1-dimethylpiperazinium iodide
nAChR agonist
0395 N-Acetylglycyl-D-glutamic acid
Potent convulsant
0384 N-Acetyl-L-leucyl-L-leucyl-L-methional
Cathepsin inhibitor
0351 1-Acetyl-4-methylpiperazine hydrochloride
nAChR agonist
5679 N-Acetylpuromycin
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
0357 N-Acetyltryptamine
Substrate for serotonin N-acetyl transferase
1762 Acifran
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors
2784 Acipimox
Antilipolytic agent
5092 Acridine Orange hydrochloride
Nucleic acid binding dye
1229 Actinomycin D
Inhibits RNA polymerase
2513 Acyclovir
Inhibits viral DNA polymerase; antiherpetic agent
5940 AdTx1
Selective, high affinity, non-competitive α1A adrenoceptor antagonist
2852 Adapalene
RARβ and RARγ agonist
3716 Adaphostin
p210bcr/abl kinase inhibitor
5953 Adaptaquin
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
4202 Adenine
Adenine receptor agonist
3624 Adenosine
Endogenous adenosine receptor agonist
3633 Adenosine 5'-(α,β-methylene)diphosphate sodium salt
Ecto-5'-nucleotidase (CD73) inhibitor
5096 AdipoRon hydrochloride
Orally active AdipoR1 and AdipoR2 agonist; antidiabetic
6812 Afatinib dimaleate
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
2799 ω-Agatoxin IVA
CaV2.1 blocker
2802 ω-Agatoxin TK
CaV2.1 blocker
5195 Agitoxin 2
Potent Shaker K+ channel blocker
0842 Agmatine sulfate
α2 ligand. Also imidazoline ligand
6161 Ailanthone
Potent inhibitor of androgen receptor (AR)
1353 Akt/SKG Substrate Peptide
Akt/PKB substrate (synthetic)
5773 Akti-1/2
Potent and selective dual Akt1 and 2 inhibitor
5823 Ala-Gln
Stable form of L-glutamine; commonly used in cell culture
0205 L-Alanine
Glycine receptor agonist
0206 β-Alanine
Endogenous glycine agonist, more selective than taurine (Cat. No. 0209)
4490 Alantolactone
Antiproliferative; induces activin/Smad3 signaling
4005 Alda 1
ALDH2 activator; cardioprotective
3979 Alexidine dihydrochloride
Selective inhibitor of PTPMT1
4159 Alfacalcidol
Prodrug of vitamin D3 (Cat. No. 4156)
3305 Alfuzosin hydrochloride
Uroselective α1 antagonist
5491 Aliskiren hemifumarate
Potent renin inhibitor; antihypertensive
3653 Allopregnanolone
Positive allosteric modulator of GABAA receptors
2806 Alprenolol hydrochloride
β antagonist; also 5-HT1A antagonist
1620 Alprostadil
Prostaglandin. Vasodilator and antiplatelet agent in vivo
0485 Alrestatin
Aldose reductase inhibitor
6400 Alsterpaullone
Potent cdk1 and cdk2 inhibitor; also inhibits GSK-3β and Lck
1809 Altanserin hydrochloride
5-HT2A receptor antagonist
1893 Alytesin
Amphibian bombesin-like peptide
4025 α-Amanitin
Inhibitor of RNA polymerase II
0388 Ambenonium dichloride
Cholinesterase inhibitor
5828 Ambrisentan
Selective ETA antagonist
2404 Ambroxol hydrochloride
Na+ channel blocker
6547 Ambuic Acid
Quorum sensing inhibitor; antibacterial
6655 Amifostine
Cytoprotectant
0890 Amiloride hydrochloride
Na+ channel blocker; also I2 imidazoline ligand
7121 7-Aminoactinomycin D
Fluorescent DNA stain
4050 8-Aminoadenine
Adenine receptor agonist
0788 3-Aminobenzamide
PARP inhibitor
0787 Aminoguanidine hydrochloride
Irreversible iNOS inhibitor
0721 Aminopotentidine
H2 antagonist
2072 Aminopurvalanol A
Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
0940 4-Aminopyridine
Non-selective KV channel blocker
4095 Amiodarone hydrochloride
Broad spectrum ion channel blocker; antiarrhythmic
2132 Amisulpride
Selective D2 and D3 antagonist; atypical antipsychotic
4456 Amitriptyline hydrochloride
5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist
4857 Amlexanox
Selective inhibitor of TBK
2571 Amlodipine besylate
CaV1.x blocker
5659 AmmTX3
KV4 channel blocker
2813 D-Amphetamine sulfate
Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist
6930 Amphotericin B
Forms monovalent ion channels in lipid bilyers; antifungal
0668 Amthamine dihydrobromide
Highly selective standard H2 agonist
3418 Amylin
Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors
6030 Amylin (rat)
Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors
3391 Amyloid β-peptide (42-1) (human)
Inactive control peptide for amyloid β-peptide (1-42) (Cat. No. 1428)
7031 Amyloid β-Peptide (1-37) (human)
Amyloid β-protein fragment
1191 Amyloid β-Peptide (1-40) (human)
Amyloid β-protein fragment
2424 Amyloid β-peptide (1-40) (rat)
Amyloid β-protein fragment
1428 Amyloid β-Peptide (1-42) (human)
Predominant amyloid β-protein fragment
2425 Amyloid β-peptide (1-42) (rat)
Predominant amyloid β-protein fragment
1938 Amyloid β-Peptide (1-43) (human)
Amyloid β-protein fragment
1894 Amyloid β-Peptide (12-28) (human)
Amyloid β-peptide; minimum required for binding to brain proteins
1429 Amyloid β-peptide (25-35) (human)
Human amyloid β-protein fragment functionally required for neurotoxicity
1971 (+)-Anabasine hydrochloride
High affinity nAChR partial agonist
3084 Anacardic acid
Noncompetitive PCAF/p300 inhibitor
2432 Anagrelide hydrochloride
Potent PDE3 inhibitor
1339 Anandamide
Endogenous and non-selective CB agonist
3717 Anandamide - d4
Deuterated anandamide
3388 Anastrozole
Potent aromatase (CYP19) inhibitor
0789 (±)-Anatoxin A fumarate
nAChR agonist
4626 Andrographolide
Inhibits NFκB; blocks androgen receptor (AR) expression
1562 Angiotensin (1-7)
Vasorelaxant peptide
5335 Angiotensin A
Potent endogenous vasoconstrictor peptide - derivative of angiotensin II (Cat. No. 1158)
1563 Angiotensin I (human, mouse, rat)
Endogenous precursor to angiotensin II (Cat. No. 1158)
1158 Angiotensin II
Potent vasoconstrictor peptide
6159 4,9-Anhydrotetrodotoxin
Potent and selective Nav1.6 channel blocker
6076 Ani 9
Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker
0867 Aniracetam
Inhibits desensitization; AMPA > kainate
1290 Anisomycin
JNK, SAPK and p38 activator
6861 Anle138b
Oligomeric aggregation inhibitor; inhibits prion protein and α-synuclein aggregate formation
0703 Anpirtoline hydrochloride
Highly potent 5-HT1B agonist; also 5-HT3 antagonist
1954 Antagonist G
Broad spectrum neuropeptide receptor antagonist
2778 Antalarmin hydrochloride
CRF1 antagonist
0791 Antazoline hydrochloride
Imidazoline ligand
6556 Anti-human EGFR aptamer, Janelia Fluor® 646 conjugate
High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646
6557 Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate
High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646
2071 Antisauvagine-30
Potent, selective and competitive CRF2 antagonist
1652 Apamin
KCa2 channel blocker (small conductance)
5747 Apcin
Cdc20 inhibitor; inhibits Cdc20-substrate interaction
2420 [Pyr1]-Apelin-13
Potent peptide apelin agonist
3007 Apelin-17 (human, bovine)
Endogenous apelin agonist
2426 Apelin-36 (human)
Endogenous apelin agonist
2427 Apelin-36 (rat, mouse)
Endogenous apelin agonist
5736 Aphidicolin
DNA polymerase α, δ and ε inhibitor
1227 Apigenin
Protein kinase inhibitor
4663 Apocynin
NADPH-oxidase inhibitor
2073 (R)-(-)-Apomorphine hydrochloride
Dopamine agonist; non-subtype-selective
2098 Apoptosis Activator 2
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
6486 Aprepitant
Potent long-acting hNK1 antagonist
4139 Aprotinin
Competitive serine protease inhibitor
2756 Arachidonic acid (in Tocrisolve™100)
Endogenous free fatty acid (in water-soluble emulsion)
2836 Arachidonyl serotonin
Dual FAAH inhibitor/TRPV1 antagonist
1814 N-ArachidonylGABA
Inhibits pain in vivo
1298 2-Arachidonylglycerol
Endogenous and non-selective CB agonist; potent GPR55 agonist
1445 N-Arachidonylglycine
GPR18 agonist; endocannabinoid
0389 Arcaine sulfate
Competitive NMDA antagonist
1777 Arctigenin
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
2457 Arcyriaflavin A
Potent cdk4 inhibitor; also potently inhibits CaM kinase II; antiviral
0383 Arecaidine propargyl ester tosylate
Muscarinic agonist
6219 Arformoterol tartrate
Long-acting β2 agonist (LABA)
1637 Argatroban
Potent thrombin inhibitor
0663 L-Arginine
Endogenous substrate for NOS
5584 Aripiprazole
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
6818 Artemether
Antimalarial; also inhibits neuroinflammation
2668 Artemisinin
Antimalarial; inhibits P-type ATPase (PfATP6) of P.falciparum
6827 Artesunate
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
1354 Arvanil
Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist
4210 Ascomycin
Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)
4055 L-Ascorbic acid
Enhances the generation of iPSCs; increases reprogramming efficiency
3737 Asenapine maleate
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
0213 D-Aspartic acid
NMDA agonist
0214 L-Aspartic acid
NMDA agonist
4092 Aspirin
Cyclooxygenase inhibitor; NSAID
3489 Astemizole
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
1606 Astressin
Potent CRF antagonist
2391 Astressin 2B
Selective CRF2 antagonist
0387 (RS)-Atenolol
β1 antagonist
2937 Atipamezole hydrochloride
Selective α2 antagonist
4580 Atiprimod dihydrochloride
JAK2 inhibitor
3776 Atorvastatin hemicalcium salt
Potent HMG-CoA reductase inhibitor
6332 Atosiban
Potent oxytocin receptor antagonist
6358 Atovaquone
Inhibits complex III of mitochondrial electron transport chain in parasites
1912 Atrial natriuretic factor (1-28) (rat)
Endogenous peptide regulating blood pressure
1906 Atrial natriuretic factor (1-28) (human, porcine)
Endogenous peptide regulating blood pressure
4600 Auranofin
Thioredoxin reductase inhibitor; induces MPT
1688 Autocamtide-2-related inhibitory peptide
Selective CaM kinase II inhibitor
5959 Autocamtide-2-related inhibitory peptide, myristoylated
CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide
6324 Autophinib
Potent VPS34 inhibitor
6834 Auxin
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone
6363 Avagacestat
Highly potent γ-secretase inhibitor; orally bioavailable
6505 Avasimibe
ACAT inhibitor
4350 Axitinib
Potent VEGFR-1, -2 and -3 inhibitor
6868 8-Azaadenosine
ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor; inhibits leukemia stem cell self-renewal
3842 5-Azacytidine
DNA methyltransferase inhibitor
4099 Azathioprine
Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103)
6584 L-Azidohomoalanine hydrochloride
Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins
6585 L-Azidonorleucine hydrochloride
Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins
4150 Azidothymidine
Selective reverse transcriptase inhibitor; antiretroviral
4553 Azilsartan
Potent AT1 inverse agonist; antihypertensive
6318 Azimilide dihydrochloride
Kv11.1 (hERG) channel blocker
3771 Azithromycin
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation
5796 Azoramide
Unfolded protein response (UPR) modulator

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