Cat. No. | Product Name / Activity |
---|---|
4431 | A 1070722 |
Highly potent, selective GSK-3 inhibitor | |
3793 | A 1120 |
High affinity retinol-binding protein 4 (RBP4) ligand | |
6409 | A 1210477 |
Selective, high affinity Mcl-1 inhibitor; proapoptotic | |
5730 | A 127722 |
Highly potent, selective ETA antagonist; orally bioavailable | |
6972 | A 1899 |
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker | |
6167 | A 196 |
Potent and selective SUV420H1/H2 inhibitor | |
2524 | A 205804 |
Selective inhibitor of E-selectin and ICAM-1 expression | |
4228 | A 286982 |
Potent inhibitor of the LFA-1/ICAM-1 interaction | |
6493 | A 317491 sodium salt |
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive | |
6313 | A 33 |
Potent and selective PDE4B inhibitor | |
4697 | A 331440 dihydrochloride |
Selective H3 antagonist | |
2753 | A 350619 hydrochloride |
Soluble guanylyl cyclase (sGC) activator | |
5163 | A 366 |
Potent and selective G9a/GLP inhibitor | |
6470 | A 410099.1 |
High affinity XIAP antagonist; active in vivo | |
6473 | A 410099.1 amide-PEG2-amine |
IAP ligand with PEG linker and terminal amine for onward chemistry | |
6472 | A 410099.1 amide-PEG3-amine |
IAP ligand with PEG linker and terminal amine for onward chemistry | |
7220 | A 410099.1 amide-PEG4-amine |
IAP ligand with PEG linker and terminal amine for onward chemistry | |
7221 | A 410099.1 amide-PEG5-amine |
IAP ligand with PEG linker and terminal amine for onward chemistry | |
6474 | A 410099.1 amide-alkylC4-amine |
IAP ligand with alkyl linker and terminal amine for onward chemistry | |
6471 | A 410099.1, amine |
Functionalized IAP ligand for PROTACs | |
4552 | A 412997 dihydrochloride |
Selective D4 agonist | |
3914 | A 419259 trihydrochloride |
Inhibitor of Src family kinases | |
5781 | A 425619 |
Potent TRPV1 antagonist | |
2972 | A 438079 hydrochloride |
Competitive P2X7 antagonist | |
4483 | A 484954 |
CaM kinase III (eEF-2 kinase) inhibitor | |
6387 | A 485 |
Potent and selective p300/CBP inhibitor; orally bioavailable | |
4341 | A 582941 |
α7 nAChR partial agonist | |
1052 | A 61603 hydrobromide |
α1A agonist | |
1534 | A 68930 hydrochloride |
Potent and selective D1-like agonist | |
6715 | A 71915 |
Highly potent and competitive NPRA antagonist | |
3701 | A 740003 |
Potent and selective P2X7 antagonist | |
3336 | A 769662 |
Potent AMPK activator | |
6712 | A 77-01 |
Potent inhibitor of TGF-βRI | |
1701 | A 77636 hydrochloride |
Potent and selective D1-like agonist; orally active | |
5937 | A 779 |
Selective Mas receptor (Ang-(1-7) receptor) antagonist | |
4319 | A 784168 |
Potent and selective TRPV1 antagonist | |
2976 | A 803467 |
Selective NaV1.8 channel blocker | |
2341 | A 80426 mesylate |
High affinity α2 antagonist. Also 5-HT uptake inhibitor | |
4473 | A 804598 |
Potent and selective P2X7 antagonist | |
2939 | A 83-01 |
Selective inhibitor of TGF-βRI, ALK4 and ALK7 | |
4232 | A 839977 |
Potent P2X7 antagonist | |
4477 | A 844606 |
Selective α7 nAChR partial agonist | |
5017 | A 85380 dihydrochloride |
High affinity and selective α4β2 nAChR agonist | |
4571 | A 867744 |
Positive allosteric modulator of α7 nAChRs | |
4249 | A 887826 |
Potent voltage-dependent NaV1.8 channel blocker | |
3587 | A 922500 |
Potent DGAT-1 inhibitor | |
4845 | A 939572 |
Potent SCD-1 inhibitor | |
3753 | A 943931 dihydrochloride |
Potent and selective H4 antagonist | |
4716 | A 967079 |
Selective TRPA1 channel blocker | |
5766 | A 971432 |
Potent and selective S1P5 agonist | |
3640 | A 987306 |
Potent and selective H4 antagonist | |
2411 | A-71623 |
Potent and selective CCK1 agonist; suppresses feeding | |
5397 | A01 |
High affinity Smurf1 inhibitor; enhances BMP signaling | |
5097 | A12B4C3 |
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor | |
1234 | A23187, free acid |
Calcium ionophore | |
5802 | A37 |
ALDH1A1 inhibitor | |
5595 | A66 |
Potent and selective PI 3-kinase p110α inhibitor | |
0378 | A-7 hydrochloride |
Calmodulin antagonist | |
6759 | AA 147 |
ER proteostasis regulator | |
3025 | AA 2414 |
Thromboxane A2 (TP) receptor antagonist | |
3972 | AA 29504 |
Positive allosteric modulator of GABAA receptors | |
1462 | AACOCF3 |
Phospholipase A2 inhibitor | |
1515 | 17-AAG |
Selective Hsp90 inhibitor | |
5462 | AAQ chloride |
Photoswitchable Kv channel blocker | |
5229 | ABP 688 |
High affinity human mGlu5 antagonist | |
5038 | ABT |
Cytochrome P450 inhibitor; inhibits 20-HETE synthesis | |
5079 | ABT 089 dihydrochloride |
High affinity and selective α4β2 nAChR partial agonist | |
6960 | ABT 199 |
Selective, high affinity Bcl-2 inhibitor; orally bioavailable | |
6576 | ABT 594 hydrochloride |
Selective α4β2 nAChR agonist | |
6770 | ABT 639 |
CaV3.2 and CaV3.1 channel blocker; orally bioavailable | |
2372 | ABT 702 hydrochloride |
Adenosine kinase inhibitor; orally active | |
2214 | ABT 724 trihydrochloride |
Potent and selective D4 partial agonist; proerectile | |
6835 | ABT 737 |
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines | |
4138 | ABT 751 |
Inhibitor of microtubule polymerization; antimitotic and antitumor | |
5053 | AC 186 |
Potent and selective ERβ agonist; neuroprotective | |
3419 | AC 187 |
Potent and selective amylin antagonist | |
6766 | AC 1903 |
Selective TRPC5 blocker | |
6550 | AC 253 |
Amylin (AMY3) antagonist | |
4046 | AC 261066 |
RARβ2 agonist | |
3370 | AC 264613 |
PAR2 receptor agonist | |
6165 | AC 265347 |
Biased allosteric modulator of calcium-sensing receptor (CaSR) | |
5464 | AC 4 |
Photoswitchable TRPV1 channel blocker | |
3043 | AC 45594 |
SF-1 inverse agonist | |
5281 | AC 5216 |
Selective TSPO ligand | |
3369 | AC 55541 |
Potent and selective PAR2 agonist | |
2436 | AC 55649 |
Selective RARβ2 agonist | |
5013 | AC 710 |
Potent and selective PDGFR family inhibitor | |
2484 | (±)-AC 7954 hydrochloride |
Non-peptide UT receptor agonist | |
0963 | 9-AC |
Chloride transport inhibitor | |
0258 | ACBC |
NMDA antagonist; acts at glycine site | |
0271 | cis-ACBD |
Potent, selective L-glutamate uptake inhibitor | |
1319 | ACEA |
Potent and highly selective CB1 agonist | |
5879 | ACES |
Zwitterionic buffer; used in cell culture and gel eletrophoresis | |
2728 | ACET |
Potent kainate antagonist; displays selectivity for GluK1-containing receptors | |
4547 | ACHP |
Selective IKKα and IKKβ inhibitor | |
0284 | (1S,3R)-ACPD |
Group I and group II mGlu agonist; active isomer of (±)-trans-ACPD (Cat. No. 0187) | |
0186 | cis-ACPD |
Potent NMDA agonist; also group II mGluR agonist | |
0187 | (±)-trans-ACPD |
Group I and II mGlu agonist | |
1111 | ACPT-I |
Group III mGlu agonist | |
1112 | ACPT-II |
Competitive mGlu receptor antagonist | |
3525 | ACSF |
Artificial cerebrospinal fluid | |
4983 | ACT 335827 |
Potent and selective OX1 antagonist | |
5319 | ACT 462206 |
Potent, dual orexin receptor antagonist | |
3492 | ACTH (1-39) |
Potent endogenous MC2 agonist | |
6840 | AD 01 |
FKBPL (FK506-binding protein like)-based peptide; inhibits breast cancer stem cell self-renewal; also antiangiogenic | |
4812 | ADWX 1 |
Potent and selective KV1.3 channel blocker | |
4416 | ADX 10059 hydrochloride |
Negative allosteric modulator of mGlu5 receptors | |
5715 | (±)-ADX 71743 |
Negative allosteric modulator of mGlu7 receptors; brain penetrant | |
5175 | AEBSF |
Broad spectrum, irreversible inhibitor of serine proteases | |
5318 | AEE 788 |
Potent EGFR and VEGFR inhibitor | |
2651 | AEG 3482 |
Inhibitor of JNK signaling | |
5330 | AEG 40730 dihydrochloride |
IAP antagonist; induces apoptosis | |
1793 | AF 12198 |
Potent, selective human type I IL-1 receptor antagonist | |
6931 | AF 64394 |
Potent and selective GPR3 inverse agonist | |
1105 | AF-DX 116 |
Selective M2 antagonist | |
1345 | AF-DX 384 |
Potent M2/M4 antagonist | |
2730 | AG 045572 |
Selective GnRH receptor antagonist | |
1276 | AG 1478 hydrochloride |
Highly potent EGFR-kinase inhibitor | |
0493 | AG 18 |
EGFR/PDGFR-kinase inhibitor | |
6242 | AG 205 |
Progesterone receptor membrane component 1 (Pgrmc1) ligand | |
0414 | AG 490 |
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor | |
0619 | AG 494 |
Potent EGFR-kinase inhibitor | |
0618 | AG 555 |
Potent EGFR-kinase inhibitor | |
1555 | AG 825 |
Selective ErbB2 inhibitor | |
2617 | AG 879 |
TrkA inhibitor | |
0497 | AG 99 |
EGFR-kinase inhibitor | |
7087 | AGI 5198 |
Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1) | |
1072 | AGN 192403 hydrochloride |
I1 selective ligand | |
5758 | AGN 193109 |
High affinity pan-RAR antagonist | |
0998 | AH 11110 hydrochloride |
Subtype-selective α1B ligand | |
0671 | AH 6809 |
EP1 and EP2 receptor antagonist | |
5256 | AH 7614 |
Selective FFA4 (GPR120) antagonist | |
5145 | AI-3 |
ARE activator; induces Nrf2-ARE-dependent transcription | |
2840 | AICAR |
AMPK activator | |
0904 | AIDA |
Potent and selective group I mGlu antagonist | |
4946 | AIM 100 |
Potent and selective Ack1 (TNK2) inhibitor | |
0678 | (+)-AJ 76 hydrochloride |
Antagonist; preferential action at D2-like autoreceptors | |
4754 | AK 7 |
Selective SIRT2 inhibitor; brain penetrant | |
2422 | AKTide-2T |
Akt/PKB substrate (synthetic) | |
4753 | AL 8697 |
Potent and selective p38α inhibitor | |
1757 | ALX 5407 hydrochloride |
Selective non-transportable GlyT1 inhibitor | |
5914 | AM 0902 |
Potent and selective TRPA1 antagonist | |
2564 | AM 114 |
20S proteasome inhibitor | |
3381 | AM 1172 |
Anandamide uptake inhibitor; also FAAH inhibitor and CB receptor partial agonist | |
6495 | AM 12 |
TRPC5 inhibitor | |
6034 | AM 2394 |
Potent glucokinase activator; orally bioavailable | |
1117 | AM 251 |
Potent CB1 antagonist; also GPR55 agonist | |
1115 | AM 281 |
Potent and selective CB1 inverse agonist | |
1116 | AM 404 |
Anandamide transport inhibitor | |
6193 | AM 4113 |
High affinity and selective CB1 antagonist | |
5789 | AM 4668 |
Potent FFA1 (GPR40) agonist | |
0760 | AM 580 |
Retinoic acid analog; RARα agonist | |
1120 | AM 630 |
Selective CB2 inverse agonist | |
5443 | AM 6545 |
High affinity and selective CB1 antagonist | |
3507 | AM 80 |
RARα agonist; anticancer agent | |
6043 | AMBMP hydrochloride |
Wnt canonical signaling activator; also tubulin polymerization inhibitor | |
3299 | AMD 3100 octahydrochloride |
Highly selective CXCR4 antagonist | |
4179 | AMD 3465 hexahydrobromide |
Potent and selective CXCR4 antagonist | |
6166 | AMG 18 hydrochloride |
Potent and selective IRE1α inhibitor | |
4330 | AMG 21629 |
Potent and selective TRPV1 antagonist | |
6874 | AMG 333 |
Potent and selective TRPM8 antagonist; active in vivo | |
4487 | (±)-AMG 487 |
CXCR3 antagonist; inhibits cell migration and metastasis | |
5995 | AMG 517 |
Potent TRPV1 antagonist | |
3920 | AMG 548 |
Potent and selective p38α inhibitor | |
6082 | AMG 837 hemicalcium salt |
Potent FFA1 (GPR40) partial agonist | |
5701 | AMG 853 |
Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist | |
2316 | AMG 9810 |
Potent and selective TRPV1 competitive antagonist | |
5517 | AMG PERK 44 |
Potent and selective PERK inhibitor; orally bioavailable | |
0524 | AMI-193 |
D2-like antagonist; also selective 5-HT2 antagonist | |
2385 | AMN 082 dihydrochloride |
Selective mGlu7 agonist | |
6086 | AMP PNP |
Kir6 blocker; non-hydrolyzable AMP analog | |
1074 | (RS)-AMPA hydrobromide |
Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169) | |
0169 | (RS)-AMPA |
Selective AMPA agonist | |
0254 | (S)-AMPA |
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169) | |
1337 | cAMPS-Rp, triethylammonium salt |
cAMP antagonist | |
1333 | cAMPS-Sp, triethylammonium salt |
Cell-permeable cAMP analog | |
0871 | AMT hydrochloride |
Potent, selective iNOS inhibitor | |
3989 | AMTB hydrochloride |
TRPM8 blocker | |
4781 | ANA 12 |
TrkB receptor antagonist | |
5074 | ANQ 11125 |
Selective motilin receptor antagonist | |
3937 | ANR 94 |
Adenosine A2A antagonist | |
6481 | AP 14145 hydrochloride |
Negative allosteric modulator of KCa2 (SK) channels | |
3296 | AP 18 |
Reversible TRPA1 channel blocker | |
6130 | AP 1903 |
Chemical inducer of protein dimerization; active in vivo | |
6297 | AP 20187 New |
Chemical inducer of protein dimerization; active in vivo | |
4274 | AP 24534 |
Potent multi-kinase and pan-Bcr-Abl inhibitor | |
5498 | AP 811 |
High affinity, selective NPR3 antagonist | |
6626 | AP C5 |
Potent and selective PKG2 inhibitor | |
5962 | 3-AP |
Ribonucleotide reductase inhibitor; also an iron chelator | |
0125 | DL-AP3 |
Group I mGlu antagonist; also phosphoserine phosphatase inhibitor | |
0102 | D-AP4 |
Broad spectrum glutamatergic antagonist | |
0101 | DL-AP4 |
Broad spectrum glutamatergic antagonist | |
0103 | L-AP4 |
Selective group III mGlu agonist | |
3693 | DL-AP5 Sodium salt |
Potent and selective NMDA antagonist; sodium salt of DL-AP5 | |
0106 | D-AP5 |
Potent and selective NMDA receptor antagonist; more active form of DL-AP5 | |
0105 | DL-AP5 |
Potent and selective NMDA antagonist | |
0107 | L-AP5 |
Potent and selective NMDA antagonist; less active form of DL-AP5 | |
0341 | L-AP6 |
Selective agonist of the 'quis' effect | |
0104 | DL-AP7 |
Selective NMDA antagonist | |
1224 | 2-APB |
IP3 receptor antagonist. Also TRP channel modulator | |
2511 | APC 366 |
Tryptase inhibitor | |
1208 | (2R,4R)-APDC |
Highly selective group II agonist | |
4804 | APETx2 |
ASIC3 channel blocker | |
3897 | API-1 |
Selective Akt/PKB inhibitor. Antitumor | |
2151 | API-2 |
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral | |
1073 | (RS)-APICA |
Selective group II mGlu antagonist | |
4865 | APY 29 |
Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity | |
2292 | AQ-RA 741 |
High affinity and selective M2 antagonist | |
0666 | 3-AQC |
5-HT3 antagonist | |
6163 | AR 420626 |
FFA3 agonist | |
3966 | AR-A 014418 |
Selective GSK-3 inhibitor | |
3969 | AR-C 102222 |
Selective iNOS inhibitor | |
4890 | AR-C 118925XX |
Selective and competitive P2Y2 antagonist | |
5658 | AR-C 141990 hydrochloride |
MCT1 inhibitor | |
3321 | AR-C 66096 tetrasodium salt |
Potent and selective P2Y12 antagonist | |
5720 | AR-C 69931 tetrasodium salt |
Highly potent P2Y12 antagonist | |
4960 | AR-C155858 |
MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells | |
4335 | AR-M 1000390 hydrochloride |
Low-internalizing δ agonist | |
0928 | ARC 239 dihydrochloride |
α2B antagonist | |
7254 | ARCC 4 New |
Potent and selective androgen receptor degrader | |
7255 | ARCC 4 negative control New |
Negative control for ARCC 4 (Cat. No. 7254) | |
3319 | ARL 17477 dihydrochloride |
Selective nNOS inhibitor | |
1283 | ARL 67156 trisodium salt |
NTPDase inhibitor | |
5862 | ARN 14686 |
Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe | |
5861 | ARN 726 |
Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe | |
2621 | ARP 100 |
Selective inhibitor of MMP-2 | |
2622 | ARP 101 |
Inhibitor of MMP-2 | |
4676 | ARRY 520 trifluoroacetate |
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation | |
2446 | AS 101 |
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release | |
4177 | AS 1269574 |
GPR119 receptor agonist | |
4265 | AS 1842856 |
Potent and selective Foxo1 inhibitor; orally bioavailable | |
4927 | AS 1892802 |
Potent ROCK inhibitor; orally bioavailable | |
1968 | AS 19 |
Potent 5-HT7 agonist | |
3718 | AS 1949490 |
SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor | |
5035 | AS 2034178 |
Selective FFA1 (GPR40) agonist | |
5430 | AS 2444697 |
Potent and selective IRAK4 inhibitor | |
3671 | AS 252424 |
Selective inhibitor of PI 3-kinase γ | |
3578 | AS 605240 |
Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor | |
6044 | AS 8351 |
Induces reprogramming of fibroblasts into functional cardiomyocytes | |
6316 | ASB 14780 |
Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable | |
5308 | ASP 2535 |
Potent and selective GlyT1 inhibitor | |
5310 | ASP 3026 |
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor | |
5178 | ASP 7663 |
Selective TRPA1 activator | |
6084 | ASP 9521 |
Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable | |
6356 | AT 1 |
(+)-JQ1 based PROTAC with selectivity for BRD4 | |
3367 | AT 101 |
Downregulates Bcl-2 and Mcl-1; pro-apoptotic | |
4468 | AT 1015 |
Long-acting 5-HT2A antagonist | |
3531 | AT 56 |
L-PGDS inhibitor | |
7001 | AT 7867 |
Potent pan-Akt and PKA inhibitor | |
3346 | ATC 0175 hydrochloride |
MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist | |
5795 | ATI 2341 |
CXCR4 allosteric agonist | |
6058 | ATN 161 |
α5β1 integrin receptor antagonist | |
3245 | ATP disodium salt |
P2 agonist | |
1107 | ATPA |
Potent and selective GluK1 kainate agonist | |
4080 | ATPγS tetralithium salt |
Non-selective P2 agonist; analog of ATP (Cat. No. 3245) | |
4397 | AV 412 |
Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases | |
6763 | AVE 1625 |
Potent and selective CB1 receptor antagonist | |
3126 | d[Cha4]-AVP |
Potent and selective human V1B agonist | |
5843 | AX 15836 |
Potent and selective ERK5 inhibitor | |
1639 | AY 9944 dihydrochloride |
Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase | |
1487 | AY-NH2 |
Selective PAR4 agonist | |
5872 | AZ 10397767 |
Potent CXCR2 antagonist | |
3323 | AZ 10606120 dihydrochloride |
Potent P2X7 antagonist | |
3317 | AZ 11645373 |
Potent and selective human P2X7 antagonist | |
4838 | AZ 12080282 dihydrochloride |
Inhibitor of Hedgehog (Hh) signaling | |
4832 | AZ 12216052 |
Positive allosteric modulator of mGlu8 receptors | |
6870 | AZ 12799734 |
Potent TGF-βRI inhibitor | |
6177 | AZ 13705339 |
Highly potent PAK1 and PAK2 inhibitor | |
6826 | AZ 1729 |
FFA2 allosteric agonist; displays bias for the Gi signaling pathway | |
5232 | AZ 191 |
Potent DYRK1B inhibitor | |
5198 | AZ 20 |
Potent and selective ATR kinase inhibitor; antitumor | |
3994 | AZ 3146 |
Potent and selective Mps1 kinase inhibitor | |
6806 | AZ 3451 |
Potent negative allosteric modulator of PAR2 receptors | |
6330 | AZ 5704 |
Potent and selective ATM kinase inhibitor; orally bioavailable | |
5775 | AZ 6102 |
Potent TNKS1/2 inhibitor | |
4836 | AZ 628 |
Potent Raf kinase inhibitor | |
5632 | AZ Dyrk1B 33 |
Potent and selective Dyrk1B kinase inhibitor | |
5675 | AZ PFKFB3 26 |
Potent and selective PFKFB3 inhibitor | |
5742 | AZ PFKFB3 67 |
Potent and selective PFKFB3 inhibitor | |
6310 | AZD 1208 |
Potent pan Pim kinase inhibitor | |
6085 | AZD 1283 |
High affinity P2Y12 antagonist | |
5617 | AZD 1480 |
Potent and selective JAK2 inhibitor; antiangiogenic | |
5614 | AZD 2066 |
mGlu5 antagonist; orally bioavailable and brain penetrant | |
6541 | AZD 2098 |
Potent and selective CCR4 antagonist | |
6060 | AZD 2461 |
Potent PARP inhibitor; orally bioavailable | |
5615 | AZD 3147 |
Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable | |
4837 | AZD 3988 |
Potent and selective DGAT-1 inhibitor | |
6978 | AZD 5363 |
Potent pan-AKT inhibitor | |
3968 | AZD 5438 |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9 | |
5141 | AZD 5582 dihydrochloride |
Dimeric Smac mimetic; potent IAP inhibitor | |
4839 | AZD 6482 |
Potent and selective PI 3-Kβ inhibitor | |
5199 | AZD 7762 hydrochloride |
Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing | |
5613 | AZD 9272 |
Potent and selective mGlu5 antagonist; brain penetrant | |
3963 | AZM 475271 |
Src tyrosine kinase inhibitor | |
5113 | AbK |
Photo-crosslinking probe; unnatural amino acid | |
4148 | Abacavir hemisulfate |
Reverse transcriptase inhibitor; antiretroviral | |
6520 | Abiraterone acetate |
Potent CYP17A1 inhibitor | |
1297 | Abn-CBD |
Selective GPR55 agonist; neurobehaviorally inactive | |
6554 | (+)-Abscisic Acid |
Endogenous LANCL2 agonist | |
1846 | Ac2-12 |
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation | |
1845 | Ac2-26 |
Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation | |
3231 | Ac9-25 |
Annexin I N-terminal peptide; acts as a FPR1 ligand | |
3618 | Acamprosate calcium |
GABA agonist; also glutamatergic modulator | |
2673 | Acarbose |
Glucosidase α inhibitor (intestinal) | |
6006 | Acein |
High affinity angiotensin-converting enzyme (ACE) ligand | |
3069 | Acephate |
Anticholinesterase insecticide | |
1706 | Acetaminophen |
Cyclooxygenase inhibitor; may be selective for COX-3 | |
6742 | Acetazolamide |
Carbonic anhydrase inhibitor | |
5852 | Acetyl Pepstatin |
High affinity HIV-1 and HIV-2 protease inhibitor | |
1930 | N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide |
Phosphopeptide ligand for src SH2 domain | |
1927 | N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu |
Phosphopeptide ligand for src SH2 domain | |
0355 | (±)-Acetylcarnitine chloride |
Intermediate in lipid metabolism | |
2809 | Acetylcholine chloride |
Endogenous neurotransmitter | |
5619 | N-Acetylcysteine amide |
Glutathione (GSH) precursor; neuroprotective | |
0352 | 4-Acetyl-1,1-dimethylpiperazinium iodide |
nAChR agonist | |
0395 | N-Acetylglycyl-D-glutamic acid |
Potent convulsant | |
0351 | 1-Acetyl-4-methylpiperazine hydrochloride |
nAChR agonist | |
5679 | N-Acetylpuromycin |
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling | |
0357 | N-Acetyltryptamine |
Substrate for serotonin N-acetyl transferase | |
1762 | Acifran |
Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors | |
2784 | Acipimox |
Antilipolytic agent | |
5092 | Acridine Orange hydrochloride |
Nucleic acid binding dye | |
1229 | Actinomycin D |
Inhibits RNA polymerase | |
2513 | Acyclovir |
Inhibits viral DNA polymerase; antiherpetic agent | |
5940 | AdTx1 |
Selective, high affinity, non-competitive α1A adrenoceptor antagonist | |
2852 | Adapalene |
RARβ and RARγ agonist | |
5953 | Adaptaquin |
HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant | |
4202 | Adenine |
Adenine receptor agonist | |
3624 | Adenosine |
Endogenous adenosine receptor agonist | |
3633 | Adenosine 5'-(α,β-methylene)diphosphate sodium salt |
Ecto-5'-nucleotidase (CD73) inhibitor | |
5096 | AdipoRon hydrochloride |
Orally active AdipoR1 and AdipoR2 agonist; antidiabetic | |
6812 | Afatinib dimaleate |
Potent dual specificity EGFR/HER2 inhibitor; active in vivo | |
2799 | ω-Agatoxin IVA |
CaV2.1 blocker | |
2802 | ω-Agatoxin TK |
CaV2.1 blocker | |
5195 | Agitoxin 2 |
Potent Shaker K+ channel blocker | |
6161 | Ailanthone |
Potent inhibitor of androgen receptor (AR) | |
1353 | Akt/SKG Substrate Peptide |
Akt/PKB substrate (synthetic) | |
5773 | Akti-1/2 |
Potent and selective dual Akt1 and 2 inhibitor | |
5823 | Ala-Gln |
Stable form of L-glutamine; commonly used in cell culture | |
0205 | L-Alanine |
Glycine receptor agonist | |
0206 | β-Alanine |
Endogenous glycine agonist, more selective than taurine (Cat. No. 0209) | |
4490 | Alantolactone |
Antiproliferative; induces activin/Smad3 signaling | |
4005 | Alda 1 |
ALDH2 activator; cardioprotective | |
3979 | Alexidine dihydrochloride |
Selective inhibitor of PTPMT1 | |
4159 | Alfacalcidol |
Prodrug of vitamin D3 (Cat. No. 4156) | |
3305 | Alfuzosin hydrochloride |
Uroselective α1 antagonist | |
5491 | Aliskiren hemifumarate |
Potent renin inhibitor; antihypertensive | |
3653 | Allopregnanolone |
Positive allosteric modulator of GABAA receptors | |
2806 | Alprenolol hydrochloride |
β antagonist; also 5-HT1A antagonist | |
1620 | Alprostadil |
Prostaglandin. Vasodilator and antiplatelet agent in vivo | |
0485 | Alrestatin |
Aldose reductase inhibitor | |
6400 | Alsterpaullone |
Potent cdk1 and cdk2 inhibitor; also inhibits GSK-3β and Lck | |
1809 | Altanserin hydrochloride |
5-HT2A receptor antagonist | |
1893 | Alytesin |
Amphibian bombesin-like peptide | |
4025 | α-Amanitin |
Inhibitor of RNA polymerase II | |
0388 | Ambenonium dichloride |
Cholinesterase inhibitor | |
5828 | Ambrisentan |
Selective ETA antagonist | |
2404 | Ambroxol hydrochloride |
Na+ channel blocker | |
6655 | Amifostine |
Cytoprotectant | |
0890 | Amiloride hydrochloride |
Na+ channel blocker; also I2 imidazoline ligand | |
7121 | 7-Aminoactinomycin D |
Fluorescent DNA stain | |
4050 | 8-Aminoadenine |
Adenine receptor agonist | |
0788 | 3-Aminobenzamide |
PARP inhibitor | |
0787 | Aminoguanidine hydrochloride |
Irreversible iNOS inhibitor | |
0721 | Aminopotentidine |
H2 antagonist | |
2072 | Aminopurvalanol A |
Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5 | |
0940 | 4-Aminopyridine |
Non-selective KV channel blocker | |
7370 | 3-Aminotyrosine New |
Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors | |
4095 | Amiodarone hydrochloride |
Broad spectrum ion channel blocker; antiarrhythmic | |
2132 | Amisulpride |
Selective D2 and D3 antagonist; atypical antipsychotic | |
4456 | Amitriptyline hydrochloride |
5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist | |
4857 | Amlexanox |
Selective inhibitor of TBK | |
2571 | Amlodipine besylate |
CaV1.x blocker | |
5659 | AmmTX3 |
KV4 channel blocker | |
2813 | D-Amphetamine sulfate |
Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist | |
6930 | Amphotericin B |
Forms monovalent ion channels in lipid bilyers; antifungal | |
0668 | Amthamine dihydrobromide |
Highly selective standard H2 agonist | |
3418 | Amylin |
Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors | |
6030 | Amylin (rat) |
Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors | |
3391 | Amyloid β-peptide (42-1) (human) |
Inactive control peptide for amyloid β-peptide (1-42) (Cat. No. 1428) | |
7031 | Amyloid β-Peptide (1-37) (human) |
Amyloid β-protein fragment | |
1191 | Amyloid β-Peptide (1-40) (human) |
Amyloid β-protein fragment | |
2424 | Amyloid β-peptide (1-40) (rat) |
Amyloid β-protein fragment | |
1428 | Amyloid β-Peptide (1-42) (human) |
Predominant amyloid β-protein fragment | |
2425 | Amyloid β-peptide (1-42) (rat) |
Predominant amyloid β-protein fragment | |
1938 | Amyloid β-Peptide (1-43) (human) |
Amyloid β-protein fragment | |
1894 | Amyloid β-Peptide (12-28) (human) |
Amyloid β-peptide; minimum required for binding to brain proteins | |
1429 | Amyloid β-peptide (25-35) (human) |
Human amyloid β-protein fragment functionally required for neurotoxicity | |
1971 | (+)-Anabasine hydrochloride |
High affinity nAChR partial agonist | |
3084 | Anacardic acid |
Noncompetitive PCAF/p300 inhibitor | |
2432 | Anagrelide hydrochloride |
Potent PDE3 inhibitor | |
1339 | Anandamide |
Endogenous and non-selective CB agonist | |
3717 | Anandamide - d4 |
Deuterated anandamide | |
3388 | Anastrozole |
Potent aromatase (CYP19) inhibitor | |
0789 | (±)-Anatoxin A fumarate |
nAChR agonist | |
4626 | Andrographolide |
Inhibits NFκB; blocks androgen receptor (AR) expression | |
1562 | Angiotensin (1-7) |
Vasorelaxant peptide | |
5335 | Angiotensin A |
Potent endogenous vasoconstrictor peptide - derivative of angiotensin II (Cat. No. 1158) | |
1563 | Angiotensin I (human, mouse, rat) |
Endogenous precursor to angiotensin II (Cat. No. 1158) | |
1158 | Angiotensin II |
Potent vasoconstrictor peptide | |
6159 | 4,9-Anhydrotetrodotoxin |
Potent and selective Nav1.6 channel blocker | |
6076 | Ani 9 |
Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker | |
0867 | Aniracetam |
Inhibits desensitization; AMPA > kainate | |
1290 | Anisomycin |
JNK, SAPK and p38 activator | |
6861 | Anle138b |
Oligomeric aggregation inhibitor; inhibits prion protein and α-synuclein aggregate formation | |
0703 | Anpirtoline hydrochloride |
Highly potent 5-HT1B agonist; also 5-HT3 antagonist | |
1954 | Antagonist G |
Broad spectrum neuropeptide receptor antagonist | |
2778 | Antalarmin hydrochloride |
CRF1 antagonist | |
0791 | Antazoline hydrochloride |
Imidazoline ligand | |
6556 | Anti-human EGFR aptamer, Janelia Fluor® 646 conjugate |
High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646 | |
6557 | Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate |
High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646 | |
2071 | Antisauvagine-30 |
Potent, selective and competitive CRF2 antagonist | |
1652 | Apamin |
KCa2 (SK) channel blocker | |
5747 | Apcin |
Cdc20 inhibitor; inhibits Cdc20-substrate interaction | |
2420 | [Pyr1]-Apelin-13 |
Potent peptide apelin agonist | |
3007 | Apelin-17 (human, bovine) |
Endogenous apelin agonist | |
2426 | Apelin-36 (human) |
Endogenous apelin agonist | |
2427 | Apelin-36 (rat, mouse) |
Endogenous apelin agonist | |
5736 | Aphidicolin |
DNA polymerase α, δ and ε inhibitor | |
1227 | Apigenin |
Protein kinase inhibitor | |
7283 | Apilimod dimesylate New |
Potent and selective PIKfyve inhibitor | |
4663 | Apocynin |
NADPH-oxidase inhibitor | |
2073 | (R)-(-)-Apomorphine hydrochloride |
Dopamine agonist; non-subtype-selective | |
2098 | Apoptosis Activator 2 |
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis | |
6486 | Aprepitant |
Potent long-acting hNK1 antagonist | |
4139 | Aprotinin |
Competitive serine protease inhibitor | |
2836 | Arachidonyl serotonin |
Dual FAAH inhibitor/TRPV1 antagonist | |
1814 | N-ArachidonylGABA |
Inhibits pain in vivo | |
1298 | 2-Arachidonylglycerol |
Endogenous and non-selective CB agonist; potent GPR55 agonist | |
1445 | N-Arachidonylglycine |
GPR18 agonist; endocannabinoid | |
7235 | Arbidol |
Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral | |
0389 | Arcaine sulfate |
Competitive NMDA antagonist | |
1777 | Arctigenin |
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation | |
2457 | Arcyriaflavin A |
Potent cdk4 inhibitor; also potently inhibits CaM kinase II; antiviral | |
0383 | Arecaidine propargyl ester tosylate |
Muscarinic agonist | |
6219 | Arformoterol tartrate |
Long-acting β2 agonist (LABA) | |
1637 | Argatroban |
Potent thrombin inhibitor | |
0663 | L-Arginine |
Endogenous substrate for NOS | |
5584 | Aripiprazole |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist | |
6818 | Artemether |
Antimalarial; also inhibits neuroinflammation | |
2668 | Artemisinin |
Antimalarial; inhibits P-type ATPase (PfATP6) of P.falciparum | |
6827 | Artesunate |
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial | |
1354 | Arvanil |
Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist | |
4210 | Ascomycin |
Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631) | |
4055 | L-Ascorbic acid |
Enhances the generation of iPSCs; increases reprogramming efficiency | |
3737 | Asenapine maleate |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent | |
0213 | D-Aspartic acid |
NMDA agonist | |
4092 | Aspirin |
Cyclooxygenase inhibitor; NSAID | |
3489 | Astemizole |
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker | |
1606 | Astressin |
Potent CRF antagonist | |
2391 | Astressin 2B |
Selective CRF2 antagonist | |
0387 | (RS)-Atenolol |
β1 antagonist | |
2937 | Atipamezole hydrochloride |
Selective α2 antagonist | |
4580 | Atiprimod dihydrochloride |
JAK2 inhibitor | |
6332 | Atosiban |
Potent oxytocin receptor antagonist | |
1912 | Atrial natriuretic factor (1-28) (rat) |
Endogenous peptide regulating blood pressure | |
1906 | Atrial natriuretic factor (1-28) (human, porcine) |
Endogenous peptide regulating blood pressure | |
4600 | Auranofin |
Thioredoxin reductase inhibitor; induces MPT | |
1688 | Autocamtide-2-related inhibitory peptide |
Selective CaM kinase II inhibitor | |
5959 | Autocamtide-2-related inhibitory peptide, myristoylated |
CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide | |
6324 | Autophinib |
Potent VPS34 inhibitor | |
6834 | Auxin |
Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone | |
6363 | Avagacestat |
Highly potent γ-secretase inhibitor; orally bioavailable | |
6505 | Avasimibe |
ACAT inhibitor | |
4350 | Axitinib |
Potent VEGFR-1, -2 and -3 inhibitor | |
6868 | 8-Azaadenosine |
ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor; inhibits leukemia stem cell self-renewal | |
3842 | 5-Azacytidine |
DNA methyltransferase inhibitor | |
4099 | Azathioprine |
Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103) | |
6584 | L-Azidohomoalanine hydrochloride |
Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins | |
6585 | L-Azidonorleucine hydrochloride |
Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins | |
4150 | Azidothymidine |
Selective reverse transcriptase inhibitor; antiretroviral | |
4553 | Azilsartan |
Potent AT1 inverse agonist; antihypertensive | |
6318 | Azimilide dihydrochloride |
Kv11.1 (hERG) channel blocker | |
3771 | Azithromycin |
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation | |
5796 | Azoramide |
Unfolded protein response (UPR) modulator |