| Cat. No. |
Product Name / Activity |
| 4431 |
A 1070722 |
| Highly potent, selective GSK-3 inhibitor |
| 3793 |
A 1120 |
| High affinity retinol-binding protein 4 (RBP4) ligand |
| 6409 |
A 1210477 |
| Selective, high affinity Mcl-1 inhibitor; proapoptotic |
| 5730 |
A 127722 |
| Highly potent, selective ETA antagonist; orally bioavailable |
| 6972 |
A 1899 |
| Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker |
| 6167 |
A 196 |
| Potent and selective SUV420H1/H2 inhibitor |
| 2524 |
A 205804 |
| Selective inhibitor of E-selectin and ICAM-1 expression |
| 4228 |
A 286982 |
| Potent inhibitor of the LFA-1/ICAM-1 interaction |
| 6493 |
A 317491 sodium salt |
| Selective, high affinity P2X3 and P2X2/3 receptor antagonist; antinociceptive |
| 6313 |
A 33 |
| Potent and selective PDE4B inhibitor |
| 4697 |
A 331440 dihydrochloride |
| Selective H3 antagonist |
| 2753 |
A 350619 hydrochloride |
| Soluble guanylyl cyclase (sGC) activator |
| 5163 |
A 366 |
| Potent and selective G9a/GLP inhibitor |
| 6470 |
A 410099.1 |
| High affinity XIAP antagonist; active in vivo |
| 6473 |
A 410099.1 amide-PEG2-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry |
| 6472 |
A 410099.1 amide-PEG3-amine |
| IAP ligand with PEG linker and terminal amine for onward chemistry |
| 7220 |
A 410099.1 amide-PEG4-amine New |
| IAP ligand with PEG linker and terminal amine for onward chemistry |
| 7221 |
A 410099.1 amide-PEG5-amine New |
| IAP ligand with PEG linker and terminal amine for onward chemistry |
| 6474 |
A 410099.1 amide-alkylC4-amine |
| IAP ligand with alkyl linker and terminal amine for onward chemistry |
| 6471 |
A 410099.1, amine |
| Functionalized IAP ligand for PROTACs |
| 4552 |
A 412997 dihydrochloride |
| Selective D4 agonist |
| 3914 |
A 419259 trihydrochloride |
| Inhibitor of Src family kinases |
| 5781 |
A 425619 |
| Potent TRPV1 antagonist |
| 2972 |
A 438079 hydrochloride |
| Competitive P2X7 antagonist |
| 4483 |
A 484954 |
| CaM kinase III (eEF-2 kinase) inhibitor |
| 6387 |
A 485 |
| Potent and selective p300/CBP inhibitor; orally bioavailable |
| 4341 |
A 582941 |
| α7 nAChR partial agonist |
| 1052 |
A 61603 hydrobromide |
| α1A agonist |
| 1534 |
A 68930 hydrochloride |
| Potent and selective D1-like agonist |
| 6715 |
A 71915 |
| Highly potent and competitive NPRA antagonist |
| 3701 |
A 740003 |
| Potent and selective P2X7 antagonist |
| 3336 |
A 769662 |
| Potent AMPK activator |
| 6712 |
A 77-01 |
| Potent inhibitor of TGF-βRI |
| 1701 |
A 77636 hydrochloride |
| Potent and selective D1-like agonist; orally active |
| 5937 |
A 779 |
| Selective Mas receptor (Ang-(1-7) receptor) antagonist |
| 4319 |
A 784168 |
| Potent and selective TRPV1 antagonist |
| 2976 |
A 803467 |
| Selective NaV1.8 channel blocker |
| 2341 |
A 80426 mesylate |
| High affinity α2 antagonist. Also 5-HT uptake inhibitor |
| 4473 |
A 804598 |
| Potent and selective P2X7 antagonist |
| 2939 |
A 83-01 |
| Selective inhibitor of TGF-βRI, ALK4 and ALK7 |
| 4232 |
A 839977 |
| Potent P2X7 antagonist |
| 4477 |
A 844606 |
| Selective α7 nAChR partial agonist |
| 5017 |
A 85380 dihydrochloride |
| High affinity and selective α4β2 nAChR agonist |
| 4571 |
A 867744 |
| Positive allosteric modulator of α7 nAChRs |
| 4249 |
A 887826 |
| Potent voltage-dependent NaV1.8 channel blocker |
| 3587 |
A 922500 |
| Potent DGAT-1 inhibitor |
| 4845 |
A 939572 |
| Potent SCD-1 inhibitor |
| 3753 |
A 943931 dihydrochloride |
| Potent and selective H4 antagonist |
| 4716 |
A 967079 |
| Selective TRPA1 channel blocker |
| 5766 |
A 971432 |
| Potent and selective S1P5 agonist |
| 3640 |
A 987306 |
| Potent and selective H4 antagonist |
| 2411 |
A-71623 |
| Potent and selective CCK1 agonist; suppresses feeding |
| 5397 |
A01 |
| High affinity Smurf1 inhibitor; enhances BMP signaling |
| 5097 |
A12B4C3 |
| Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor |
| 1234 |
A23187, free acid |
| Calcium ionophore |
| 5802 |
A37 |
| ALDH1A1 inhibitor |
| 5595 |
A66 |
| Potent and selective PI 3-kinase p110α inhibitor |
| 0378 |
A-7 hydrochloride |
| Calmodulin antagonist |
| 6759 |
AA 147 |
| ER proteostasis regulator |
| 3025 |
AA 2414 |
| Thromboxane A2 (TP) receptor antagonist |
| 3972 |
AA 29504 |
| Positive allosteric modulator of GABAA receptors |
| 1462 |
AACOCF3 |
| Phospholipase A2 inhibitor |
| 1515 |
17-AAG |
| Selective Hsp90 inhibitor |
| 5462 |
AAQ chloride |
| Photoswitchable Kv channel blocker |
| 5229 |
ABP 688 |
| High affinity human mGlu5 antagonist |
| 5038 |
ABT |
| Cytochrome P450 inhibitor; inhibits 20-HETE synthesis |
| 5079 |
ABT 089 dihydrochloride |
| High affinity and selective α4β2 nAChR partial agonist |
| 6960 |
ABT 199 |
| Selective, high affinity Bcl-2 inhibitor; orally bioavailable |
| 6576 |
ABT 594 hydrochloride |
| Selective α4β2 nAChR agonist |
| 6770 |
ABT 639 |
| CaV3.2 and CaV3.1 channel blocker; orally bioavailable |
| 2372 |
ABT 702 hydrochloride |
| Adenosine kinase inhibitor; orally active |
| 2214 |
ABT 724 trihydrochloride |
| Potent and selective D4 partial agonist; proerectile |
| 6835 |
ABT 737 |
| Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines |
| 4138 |
ABT 751 |
| Inhibitor of microtubule polymerization; antimitotic and antitumor |
| 5053 |
AC 186 |
| Potent and selective ERβ agonist; neuroprotective |
| 3419 |
AC 187 |
| Potent and selective amylin antagonist |
| 6766 |
AC 1903 |
| Selective TRPC5 blocker |
| 6550 |
AC 253 |
| Amylin (AMY3) antagonist |
| 4046 |
AC 261066 |
| RARβ2 agonist |
| 3370 |
AC 264613 |
| PAR2 receptor agonist |
| 6165 |
AC 265347 |
| Biased allosteric modulator of calcium-sensing receptor (CaSR) |
| 5464 |
AC 4 |
| Photoswitchable TRPV1 channel blocker |
| 3043 |
AC 45594 |
| SF-1 inverse agonist |
| 5281 |
AC 5216 |
| Selective TSPO ligand |
| 3369 |
AC 55541 |
| Potent and selective PAR2 agonist |
| 2436 |
AC 55649 |
| Selective RARβ2 agonist |
| 5013 |
AC 710 |
| Potent and selective PDGFR family inhibitor |
| 2484 |
(±)-AC 7954 hydrochloride |
| Non-peptide UT receptor agonist |
| 0963 |
9-AC |
| Chloride transport inhibitor |
| 0258 |
ACBC |
| NMDA antagonist; acts at glycine site |
| 0271 |
cis-ACBD |
| Potent, selective L-glutamate uptake inhibitor |
| 2254 |
ACDPP hydrochloride |
| Selective mGlu5 antagonist |
| 1319 |
ACEA |
| Potent and highly selective CB1 agonist |
| 5879 |
ACES |
| Zwitterionic buffer |
| 2728 |
ACET |
| Potent kainate antagonist; displays selectivity for GluK1-containing receptors |
| 4547 |
ACHP |
| Selective IKKα and IKKβ inhibitor |
| 0284 |
(1S,3R)-ACPD |
| Group I and group II mGlu agonist; active isomer of (±)-trans-ACPD (Cat. No. 0187) |
| 0186 |
cis-ACPD |
| Potent NMDA agonist; also group II mGluR agonist |
| 0187 |
(±)-trans-ACPD |
| Group I and II mGlu agonist |
| 1111 |
ACPT-I |
| Group III mGlu agonist |
| 1112 |
ACPT-II |
| Competitive mGlu receptor antagonist |
| 3525 |
ACSF |
| Artificial cerebrospinal fluid |
| 4983 |
ACT 335827 |
| Potent and selective OX1 antagonist |
| 5319 |
ACT 462206 |
| Potent, dual orexin receptor antagonist |
| 3492 |
ACTH (1-39) |
| Potent endogenous MC2 agonist |
| 6840 |
AD 01 |
| FKBPL (FK506-binding protein like)-based peptide; inhibits breast cancer stem cell self-renewal; also antiangiogenic |
| 4812 |
ADWX 1 |
| Potent and selective KV1.3 channel blocker |
| 4416 |
ADX 10059 hydrochloride |
| Negative allosteric modulator of mGlu5 receptors |
| 5715 |
(±)-ADX 71743 |
| Negative allosteric modulator of mGlu7 receptors; brain penetrant |
| 5175 |
AEBSF |
| Broad spectrum, irreversible inhibitor of serine proteases |
| 5318 |
AEE 788 |
| Potent EGFR and VEGFR inhibitor |
| 2651 |
AEG 3482 |
| Inhibitor of JNK signaling |
| 5330 |
AEG 40730 dihydrochloride |
| IAP antagonist; induces apoptosis |
| 1793 |
AF 12198 |
| Potent, selective human type I IL-1 receptor antagonist |
| 6931 |
AF 64394 |
| Potent and selective GPR3 inverse agonist |
| 1105 |
AF-DX 116 |
| Selective M2 antagonist |
| 1345 |
AF-DX 384 |
| Potent M2/M4 antagonist |
| 2730 |
AG 045572 |
| Selective GnRH receptor antagonist |
| 1276 |
AG 1478 hydrochloride |
| Highly potent EGFR-kinase inhibitor |
| 0493 |
AG 18 |
| EGFR/PDGFR-kinase inhibitor |
| 6242 |
AG 205 |
| Progesterone receptor membrane component 1 (Pgrmc1) ligand |
| 0414 |
AG 490 |
| EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor |
| 0619 |
AG 494 |
| Potent EGFR-kinase inhibitor |
| 0618 |
AG 555 |
| Potent EGFR-kinase inhibitor |
| 0616 |
AG 556 |
| EGFR-kinase inhibitor |
| 1555 |
AG 825 |
| Selective ErbB2 inhibitor |
| 2617 |
AG 879 |
| TrkA inhibitor |
| 0497 |
AG 99 |
| EGFR-kinase inhibitor |
| 7087 |
AGI 5198 New |
| Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1) |
| 3233 |
AGK 2 |
| Selective SIRT2 inhibitor |
| 1072 |
AGN 192403 hydrochloride |
| I1 selective ligand |
| 5758 |
AGN 193109 |
| High affinity pan-RAR antagonist |
| 0998 |
AH 11110 hydrochloride |
| Subtype-selective α1B ligand |
| 0671 |
AH 6809 |
| EP1 and EP2 receptor antagonist |
| 5256 |
AH 7614 |
| Selective FFA4 (GPR120) antagonist |
| 5145 |
AI-3 |
| ARE activator; induces Nrf2-ARE-dependent transcription |
| 2840 |
AICAR |
| AMPK activator |
| 0904 |
AIDA |
| Potent and selective group I mGlu antagonist |
| 4946 |
AIM 100 |
| Potent and selective Ack1 (TNK2) inhibitor |
| 0678 |
(+)-AJ 76 hydrochloride |
| Antagonist; preferential action at D2-like autoreceptors |
| 4754 |
AK 7 |
| Selective SIRT2 inhibitor; brain penetrant |
| 2422 |
AKTide-2T |
| Akt/PKB substrate (synthetic) |
| 4753 |
AL 8697 |
| Potent and selective p38α inhibitor |
| 1757 |
ALX 5407 hydrochloride |
| Selective non-transportable GlyT1 inhibitor |
| 5914 |
AM 0902 |
| Potent and selective TRPA1 antagonist |
| 2564 |
AM 114 |
| 20S proteasome inhibitor |
| 3381 |
AM 1172 |
| Anandamide uptake inhibitor; also FAAH inhibitor and CB receptor partial agonist |
| 6495 |
AM 12 |
| TRPC5 inhibitor |
| 6034 |
AM 2394 |
| Potent glucokinase activator; orally bioavailable |
| 1117 |
AM 251 |
| Potent CB1 antagonist; also GPR55 agonist |
| 1115 |
AM 281 |
| Potent and selective CB1 inverse agonist |
| 1116 |
AM 404 |
| Anandamide transport inhibitor |
| 6193 |
AM 4113 |
| High affinity and selective CB1 antagonist |
| 5789 |
AM 4668 |
| Potent FFA1 (GPR40) agonist |
| 0760 |
AM 580 |
| Retinoic acid analog; RARα agonist |
| 1120 |
AM 630 |
| Selective CB2 inverse agonist |
| 5443 |
AM 6545 |
| High affinity and selective CB1 antagonist |
| 3507 |
AM 80 |
| RARα agonist; anticancer agent |
| 6043 |
AMBMP hydrochloride |
| Wnt canonical signaling activator; also tubulin polymerization inhibitor |
| 3299 |
AMD 3100 octahydrochloride |
| Highly selective CXCR4 antagonist |
| 4179 |
AMD 3465 hexahydrobromide |
| Potent and selective CXCR4 antagonist |
| 6166 |
AMG 18 hydrochloride |
| Potent and selective IRE1α inhibitor |
| 4330 |
AMG 21629 |
| Potent and selective TRPV1 antagonist |
| 6874 |
AMG 333 |
| Potent and selective TRPM8 antagonist; active in vivo |
| 4487 |
(±)-AMG 487 |
| CXCR3 antagonist; inhibits cell migration and metastasis |
| 5995 |
AMG 517 |
| Potent TRPV1 antagonist |
| 3920 |
AMG 548 |
| Potent and selective p38α inhibitor |
| 6082 |
AMG 837 hemicalcium salt |
| Potent FFA1 (GPR40) partial agonist |
| 5701 |
AMG 853 |
| Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonist |
| 2316 |
AMG 9810 |
| Potent and selective, competitive antagonist of TRPV1 |
| 5517 |
AMG PERK 44 |
| Potent and selective PERK inhibitor; orally bioavailable |
| 0524 |
AMI-193 |
| D2-like antagonist; also selective 5-HT2 antagonist |
| 2385 |
AMN 082 dihydrochloride |
| Selective mGlu7 agonist |
| 6086 |
AMP PNP |
| Kir6 blocker; non-hydrolyzable AMP analog |
| 1074 |
(RS)-AMPA hydrobromide |
| Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169) |
| 0253 |
(R)-AMPA |
| Inactive isomer of (RS)-AMPA (Cat. No. 0169) |
| 0169 |
(RS)-AMPA |
| Selective AMPA agonist |
| 0254 |
(S)-AMPA |
| Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169) |
| 1337 |
cAMPS-Rp, triethylammonium salt |
| cAMP antagonist |
| 1333 |
cAMPS-Sp, triethylammonium salt |
| Cell-permeable cAMP analog |
| 0871 |
AMT hydrochloride |
| Potent, selective iNOS inhibitor |
| 3989 |
AMTB hydrochloride |
| TRPM8 blocker |
| 4781 |
ANA 12 |
| TrkB receptor antagonist |
| 5074 |
ANQ 11125 |
| Selective motilin receptor antagonist |
| 3937 |
ANR 94 |
| Adenosine A2A antagonist |
| 6481 |
AP 14145 hydrochloride |
| KCa2 channel negative allosteric modulator |
| 3296 |
AP 18 |
| Reversible TRPA1 channel blocker |
| 6130 |
AP 1903 New |
| Chemical inducer of protein dimerization; active in vivo |
| 4274 |
AP 24534 |
| Potent multi-kinase and pan-Bcr-Abl inhibitor |
| 5498 |
AP 811 |
| High affinity, selective NPR3 antagonist |
| 6626 |
AP C5 |
| Potent and selective PKG2 inhibitor |
| 5962 |
3-AP |
| Ribonucleotide reductase inhibitor; also an iron chelator |
| 0125 |
DL-AP3 |
| Group I mGlu antagonist; also phosphoserine phosphatase inhibitor |
| 3699 |
DL-AP4 Sodium salt |
| Broad spectrum glutamatergic antagonist; sodium salt of DL-AP4 (Cat. No. 0101) |
| 0102 |
D-AP4 |
| Broad spectrum glutamatergic antagonist |
| 0101 |
DL-AP4 |
| Broad spectrum glutamatergic antagonist |
| 0103 |
L-AP4 |
| Selective group III mGlu agonist |
| 3693 |
DL-AP5 Sodium salt |
| Potent and selective NMDA antagonist; sodium salt of DL-AP5 |
| 0106 |
D-AP5 |
| Potent and selective NMDA antagonist; more active form of DL-AP5 |
| 0105 |
DL-AP5 |
| Potent and selective NMDA antagonist |
| 0107 |
L-AP5 |
| Potent and selective NMDA antagonist; less active form of DL-AP5 |
| 0341 |
L-AP6 |
| Selective agonist of the 'quis' effect |
| 0104 |
DL-AP7 |
| Selective NMDA antagonist |
| 1224 |
2-APB |
| IP3 receptor antagonist. Also TRP channel modulator |
| 2511 |
APC 366 |
| Tryptase inhibitor |
| 1208 |
(2R,4R)-APDC |
| Highly selective group II agonist |
| 4804 |
APETx2 |
| ASIC3 channel blocker |
| 3897 |
API-1 |
| Selective Akt/PKB inhibitor. Antitumor |
| 2151 |
API-2 |
| Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral |
| 1073 |
(RS)-APICA |
| Selective group II mGlu antagonist |
| 4865 |
APY 29 |
| Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity |
| 2292 |
AQ-RA 741 |
| High affinity and selective M2 antagonist |
| 0666 |
3-AQC |
| 5-HT3 antagonist |
| 6163 |
AR 420626 |
| FFA3 agonist |
| 3966 |
AR-A 014418 |
| Selective GSK-3 inhibitor |
| 3969 |
AR-C 102222 |
| Selective iNOS inhibitor |
| 4890 |
AR-C 118925XX |
| Selective and competitive P2Y2 antagonist |
| 5658 |
AR-C 141990 hydrochloride |
| MCT1 inhibitor |
| 3321 |
AR-C 66096 tetrasodium salt |
| Potent and selective P2Y12 antagonist |
| 5720 |
AR-C 69931 tetrasodium salt |
| Highly potent P2Y12 antagonist |
| 4960 |
AR-C155858 |
| MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells |
| 4335 |
AR-M 1000390 hydrochloride |
| Low-internalizing δ agonist |
| 0928 |
ARC 239 dihydrochloride |
| α2B antagonist |
| 3319 |
ARL 17477 dihydrochloride |
| Selective nNOS inhibitor |
| 1283 |
ARL 67156 trisodium salt |
| NTPDase inhibitor |
| 5862 |
ARN 14686 |
| Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe |
| 5861 |
ARN 726 |
| Potent N-acylethanolamine acid amidase (NAAA) inhibitor; NAAA activity-based protein profiling (ABPP) probe |
| 2621 |
ARP 100 |
| Selective inhibitor of MMP-2 |
| 2622 |
ARP 101 |
| Inhibitor of MMP-2 |
| 4676 |
ARRY 520 trifluoroacetate |
| Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation |
| 2446 |
AS 101 |
| Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release |
| 4177 |
AS 1269574 |
| GPR119 receptor agonist |
| 4265 |
AS 1842856 |
| Potent and selective Foxo1 inhibitor; orally bioavailable |
| 4927 |
AS 1892802 |
| Potent ROCK inhibitor; orally bioavailable |
| 1968 |
AS 19 |
| Potent 5-HT7 agonist |
| 3718 |
AS 1949490 |
| SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2) inhibitor |
| 5035 |
AS 2034178 |
| Selective FFA1 (GPR40) agonist |
| 5430 |
AS 2444697 |
| Potent and selective IRAK4 inhibitor |
| 3671 |
AS 252424 |
| Selective inhibitor of PI 3-kinase γ |
| 3578 |
AS 605240 |
| Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor |
| 6044 |
AS 8351 |
| Induces reprogramming of fibroblasts into functional cardiomyocytes |
| 6316 |
ASB 14780 New |
| Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable |
| 5308 |
ASP 2535 |
| Potent and selective GlyT1 inhibitor |
| 5310 |
ASP 3026 |
| Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor |
| 5178 |
ASP 7663 |
| Selective TRPA1 activator |
| 6084 |
ASP 9521 |
| Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable |
| 6356 |
AT 1 |
| (+)-JQ1 based PROTAC with selectivity for BRD4 |
| 3367 |
AT 101 |
| Downregulates Bcl-2 and Mcl-1; pro-apoptotic |
| 4468 |
AT 1015 |
| Long-acting 5-HT2A antagonist |
| 3531 |
AT 56 |
| L-PGDS inhibitor |
| 7001 |
AT 7867 New |
| Potent pan-Akt and PKA inhibitor |
| 3346 |
ATC 0175 hydrochloride |
| MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist |
| 5795 |
ATI 2341 |
| CXCR4 allosteric agonist |
| 6058 |
ATN 161 |
| α5β1 integrin receptor antagonist |
| 3245 |
ATP disodium salt |
| P2 agonist |
| 1107 |
ATPA |
| Potent and selective GluK1 kainate agonist |
| 4080 |
ATPγS tetralithium salt |
| Non-selective P2 agonist; analog of ATP (Cat. No. 3245) |
| 4397 |
AV 412 |
| Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases |
| 6763 |
AVE 1625 |
| Potent and selective CB1 receptor antagonist |
| 3126 |
d[Cha4]-AVP |
| Potent and selective human V1B agonist |
| 5843 |
AX 15836 |
| Potent and selective ERK5 inhibitor |
| 1639 |
AY 9944 dihydrochloride |
| Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase |
| 1487 |
AY-NH2 |
| Selective PAR4 agonist |
| 5872 |
AZ 10397767 |
| Potent CXCR2 antagonist |
| 3323 |
AZ 10606120 dihydrochloride |
| Potent P2X7 receptor antagonist |
| 3317 |
AZ 11645373 |
| Potent and selective human P2X7 antagonist |
| 4838 |
AZ 12080282 dihydrochloride |
| Inhibitor of Hedgehog (Hh) signaling |
| 4832 |
AZ 12216052 |
| Positive allosteric modulator of mGlu8 receptors |
| 6870 |
AZ 12799734 |
| Potent TGF-βRI inhibitor |
| 6177 |
AZ 13705339 |
| Highly potent PAK1 and PAK2 inhibitor |
| 6826 |
AZ 1729 New |
| FFA2 allosteric agonist; displays bias for the Gi signaling pathway |
| 5232 |
AZ 191 |
| Potent DYRK1B inhibitor |
| 5198 |
AZ 20 |
| Potent and selective ATR kinase inhibitor; antitumor |
| 3994 |
AZ 3146 |
| Potent and selective Mps1 kinase inhibitor |
| 6806 |
AZ 3451 |
| Potent negative allosteric modulator of PAR2 receptors |
| 6330 |
AZ 5704 |
| Potent and selective ATM kinase inhibitor; orally bioavailable |
| 5775 |
AZ 6102 |
| Potent TNKS1/2 inhibitor |
| 4836 |
AZ 628 |
| Potent Raf kinase inhibitor |
| 5632 |
AZ Dyrk1B 33 |
| Potent and selective Dyrk1B kinase inhibitor |
| 5675 |
AZ PFKFB3 26 |
| Potent and selective PFKFB3 inhibitor |
| 5742 |
AZ PFKFB3 67 |
| Potent and selective PFKFB3 inhibitor |
| 6310 |
AZD 1208 |
| Potent pan Pim kinase inhibitor |
| 6085 |
AZD 1283 |
| High affinity P2Y12 antagonist |
| 5617 |
AZD 1480 |
| Potent and selective JAK2 inhibitor; antiangiogenic |
| 5614 |
AZD 2066 |
| mGlu5 antagonist; orally bioavailable and brain penetrant |
| 6541 |
AZD 2098 |
| Potent and selective CCR4 antagonist |
| 6060 |
AZD 2461 |
| Potent PARP inhibitor; orally bioavailable |
| 5615 |
AZD 3147 |
| Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable |
| 4837 |
AZD 3988 |
| Potent and selective DGAT-1 inhibitor |
| 6978 |
AZD 5363 |
| Potent pan-AKT inhibitor |
| 3968 |
AZD 5438 |
| Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9 |
| 5141 |
AZD 5582 dihydrochloride |
| Dimeric Smac mimetic; potent IAP inhibitor |
| 4839 |
AZD 6482 |
| Potent and selective PI 3-Kβ inhibitor |
| 5199 |
AZD 7762 hydrochloride |
| Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing |
| 5613 |
AZD 9272 |
| Potent and selective mGlu5 antagonist; brain penetrant |
| 3963 |
AZM 475271 |
| Src tyrosine kinase inhibitor |
| 5113 |
AbK |
| Photo-crosslinking probe; unnatural amino acid |
| 4148 |
Abacavir hemisulfate |
| Reverse transcriptase inhibitor; antiretroviral |
| 6520 |
Abiraterone acetate |
| Potent CYP17A1 inhibitor |
| 1297 |
Abn-CBD |
| Selective GPR55 agonist; neurobehaviorally inactive |
| 6554 |
(+)-Abscisic Acid |
| Endogenous LANCL2 agonist |
| 1846 |
Ac2-12 |
| Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation |
| 1845 |
Ac2-26 |
| Annexin/lipocortin 1-mimetic; inhibits leukocyte extravasation |
| 3231 |
Ac9-25 |
| Annexin I N-terminal peptide; acts as a FPR1 ligand |
| 3618 |
Acamprosate calcium |
| GABA agonist; also glutamatergic modulator |
| 2673 |
Acarbose |
| Glucosidase α inhibitor (intestinal) |
| 6006 |
Acein |
| High affinity angiotensin-converting enzyme (ACE) ligand |
| 3069 |
Acephate |
| Anticholinesterase insecticide |
| 1706 |
Acetaminophen |
| Cyclooxygenase inhibitor; may be selective for COX-3 |
| 6742 |
Acetazolamide |
| Carbonic anhydrase inhibitor |
| 5852 |
Acetyl Pepstatin |
| High affinity HIV-1 and HIV-2 protease inhibitor |
| 1930 |
N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide |
| Phosphopeptide ligand for src SH2 domain |
| 1927 |
N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu |
| Phosphopeptide ligand for src SH2 domain |
| 0355 |
(±)-Acetylcarnitine chloride |
| Intermediate in lipid metabolism |
| 2809 |
Acetylcholine chloride |
| Endogenous neurotransmitter |
| 5619 |
N-Acetylcysteine amide |
| Glutathione (GSH) precursor; neuroprotective |
| 0352 |
4-Acetyl-1,1-dimethylpiperazinium iodide |
| nAChR agonist |
| 0395 |
N-Acetylglycyl-D-glutamic acid |
| Potent convulsant |
| 0384 |
N-Acetyl-L-leucyl-L-leucyl-L-methional |
| Cathepsin inhibitor |
| 0351 |
1-Acetyl-4-methylpiperazine hydrochloride |
| nAChR agonist |
| 5679 |
N-Acetylpuromycin |
| Downregulates SnoN and Ski protein expression; promotes TGF-β signaling |
| 0357 |
N-Acetyltryptamine |
| Substrate for serotonin N-acetyl transferase |
| 1762 |
Acifran |
| Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors |
| 2784 |
Acipimox |
| Antilipolytic agent |
| 5092 |
Acridine Orange hydrochloride |
| Nucleic acid binding dye |
| 1229 |
Actinomycin D |
| Inhibits RNA polymerase |
| 2513 |
Acyclovir |
| Inhibits viral DNA polymerase; antiherpetic agent |
| 5940 |
AdTx1 |
| Selective, high affinity, non-competitive α1A adrenoceptor antagonist |
| 2852 |
Adapalene |
| RARβ and RARγ agonist |
| 3716 |
Adaphostin |
| p210bcr/abl kinase inhibitor |
| 5953 |
Adaptaquin |
| HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant |
| 4202 |
Adenine |
| Adenine receptor agonist |
| 3624 |
Adenosine |
| Endogenous adenosine receptor agonist |
| 3633 |
Adenosine 5'-(α,β-methylene)diphosphate sodium salt |
| Ecto-5'-nucleotidase (CD73) inhibitor |
| 5096 |
AdipoRon hydrochloride |
| Orally active AdipoR1 and AdipoR2 agonist; antidiabetic |
| 6812 |
Afatinib dimaleate |
| Potent dual specificity EGFR/HER2 inhibitor; active in vivo |
| 2799 |
ω-Agatoxin IVA |
| CaV2.1 blocker |
| 2802 |
ω-Agatoxin TK |
| CaV2.1 blocker |
| 5195 |
Agitoxin 2 |
| Potent Shaker K+ channel blocker |
| 0842 |
Agmatine sulfate |
| α2 ligand. Also imidazoline ligand |
| 6161 |
Ailanthone |
| Potent inhibitor of androgen receptor (AR) |
| 1353 |
Akt/SKG Substrate Peptide |
| Akt/PKB substrate (synthetic) |
| 5773 |
Akti-1/2 |
| Potent and selective dual Akt1 and 2 inhibitor |
| 5823 |
Ala-Gln |
| Stable form of L-glutamine; commonly used in cell culture |
| 0205 |
L-Alanine |
| Glycine receptor agonist |
| 0206 |
β-Alanine |
| Endogenous glycine agonist, more selective than taurine (Cat. No. 0209) |
| 4490 |
Alantolactone |
| Antiproliferative; induces activin/Smad3 signaling |
| 4005 |
Alda 1 |
| ALDH2 activator; cardioprotective |
| 3979 |
Alexidine dihydrochloride |
| Selective inhibitor of PTPMT1 |
| 4159 |
Alfacalcidol |
| Prodrug of vitamin D3 (Cat. No. 4156) |
| 3305 |
Alfuzosin hydrochloride |
| Uroselective α1 antagonist |
| 5491 |
Aliskiren hemifumarate |
| Potent renin inhibitor; antihypertensive |
| 3653 |
Allopregnanolone |
| Positive allosteric modulator of GABAA receptors |
| 2806 |
Alprenolol hydrochloride |
| β antagonist; also 5-HT1A antagonist |
| 1620 |
Alprostadil |
| Prostaglandin. Vasodilator and antiplatelet agent in vivo |
| 0485 |
Alrestatin |
| Aldose reductase inhibitor |
| 6400 |
Alsterpaullone |
| Potent cdk1 and cdk2 inhibitor; also inhibits GSK-3β and Lck |
| 1809 |
Altanserin hydrochloride |
| 5-HT2A receptor antagonist |
| 1893 |
Alytesin |
| Amphibian bombesin-like peptide |
| 4025 |
α-Amanitin |
| Inhibitor of RNA polymerase II |
| 0388 |
Ambenonium dichloride |
| Cholinesterase inhibitor |
| 5828 |
Ambrisentan |
| Selective ETA antagonist |
| 2404 |
Ambroxol hydrochloride |
| Na+ channel blocker |
| 6655 |
Amifostine |
| Cytoprotectant |
| 0890 |
Amiloride hydrochloride |
| Na+ channel blocker; also I2 imidazoline ligand |
| 7121 |
7-Aminoactinomycin D New |
| Fluorescent DNA stain |
| 4050 |
8-Aminoadenine |
| Adenine receptor agonist |
| 0788 |
3-Aminobenzamide |
| PARP inhibitor |
| 0787 |
Aminoguanidine hydrochloride |
| Irreversible iNOS inhibitor |
| 0721 |
Aminopotentidine |
| H2 antagonist |
| 2072 |
Aminopurvalanol A |
| Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5 |
| 0940 |
4-Aminopyridine |
| Non-selective KV channel blocker |
| 4095 |
Amiodarone hydrochloride |
| Broad spectrum ion channel blocker; antiarrhythmic |
| 2132 |
Amisulpride |
| Selective D2 and D3 antagonist; atypical antipsychotic |
| 4456 |
Amitriptyline hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist |
| 4857 |
Amlexanox |
| Selective inhibitor of TBK |
| 2571 |
Amlodipine besylate |
| CaV1.x blocker |
| 5659 |
AmmTX3 |
| KV4 channel blocker |
| 2813 |
D-Amphetamine sulfate |
| Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist |
| 6930 |
Amphotericin B |
| Forms monovalent ion channels in lipid bilyers; antifungal |
| 0668 |
Amthamine dihydrobromide |
| Highly selective standard H2 agonist |
| 3418 |
Amylin |
| Endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors |
| 6030 |
Amylin (rat) |
| Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors |
| 3391 |
Amyloid β-peptide (42-1) (human) |
| Inactive control peptide for amyloid β-peptide (1-42) (Cat. No. 1428) |
| 7031 |
Amyloid β-Peptide (1-37) (human) |
| Amyloid β-protein fragment |
| 1191 |
Amyloid β-Peptide (1-40) (human) |
| Amyloid β-protein fragment |
| 2424 |
Amyloid β-peptide (1-40) (rat) |
| Amyloid β-protein fragment |
| 1428 |
Amyloid β-Peptide (1-42) (human) |
| Predominant amyloid β-protein fragment |
| 2425 |
Amyloid β-peptide (1-42) (rat) |
| Predominant amyloid β-protein fragment |
| 1938 |
Amyloid β-Peptide (1-43) (human) |
| Amyloid β-protein fragment |
| 1894 |
Amyloid β-Peptide (12-28) (human) |
| Amyloid β-peptide; minimum required for binding to brain proteins |
| 1429 |
Amyloid β-peptide (25-35) (human) |
| Human amyloid β-protein fragment functionally required for neurotoxicity |
| 1971 |
(+)-Anabasine hydrochloride |
| High affinity nAChR partial agonist |
| 3084 |
Anacardic acid |
| Noncompetitive PCAF/p300 inhibitor |
| 2432 |
Anagrelide hydrochloride |
| Potent PDE3 inhibitor |
| 1339 |
Anandamide |
| Endogenous and non-selective CB agonist |
| 3717 |
Anandamide - d4 |
| Deuterated anandamide |
| 3388 |
Anastrozole |
| Potent aromatase (CYP19) inhibitor |
| 0789 |
(±)-Anatoxin A fumarate |
| nAChR agonist |
| 4626 |
Andrographolide |
| Inhibits NFκB; blocks androgen receptor (AR) expression |
| 1562 |
Angiotensin (1-7) |
| Vasorelaxant peptide |
| 5335 |
Angiotensin A |
| Potent endogenous vasoconstrictor peptide - derivative of angiotensin II (Cat. No. 1158) |
| 1563 |
Angiotensin I (human, mouse, rat) |
| Endogenous precursor to angiotensin II (Cat. No. 1158) |
| 1158 |
Angiotensin II |
| Potent vasoconstrictor peptide |
| 6159 |
4,9-Anhydrotetrodotoxin |
| Potent and selective Nav1.6 channel blocker |
| 6076 |
Ani 9 |
| Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker |
| 0867 |
Aniracetam |
| Inhibits desensitization; AMPA > kainate |
| 1290 |
Anisomycin |
| JNK, SAPK and p38 activator |
| 6861 |
Anle138b |
| Oligomeric aggregation inhibitor; inhibits prion protein and α-synuclein aggregate formation |
| 0703 |
Anpirtoline hydrochloride |
| Highly potent 5-HT1B agonist; also 5-HT3 antagonist |
| 1954 |
Antagonist G |
| Broad spectrum neuropeptide receptor antagonist |
| 2778 |
Antalarmin hydrochloride |
| CRF1 antagonist |
| 0791 |
Antazoline hydrochloride |
| Imidazoline ligand |
| 6556 |
Anti-human EGFR aptamer, Janelia Fluor® 646 conjugate |
| High affinity anti-human EGFR aptamer conjugated to Janelia Fluor® 646 |
| 6557 |
Anti-human ErbB2 aptamer, Janelia Fluor® 646 conjugate |
| High affinity anti-human ErbB2 aptamer conjugated to Janelia Fluor® 646 |
| 2071 |
Antisauvagine-30 |
| Potent, selective and competitive CRF2 antagonist |
| 1652 |
Apamin |
| KCa2 channel blocker (small conductance) |
| 5747 |
Apcin |
| Cdc20 inhibitor; inhibits Cdc20-substrate interaction |
| 2420 |
[Pyr1]-Apelin-13 |
| Potent peptide apelin agonist |
| 3007 |
Apelin-17 (human, bovine) |
| Endogenous apelin agonist |
| 2426 |
Apelin-36 (human) |
| Endogenous apelin agonist |
| 2427 |
Apelin-36 (rat, mouse) |
| Endogenous apelin agonist |
| 5736 |
Aphidicolin |
| DNA polymerase α, δ and ε inhibitor |
| 1227 |
Apigenin |
| Protein kinase inhibitor |
| 4663 |
Apocynin |
| NADPH-oxidase inhibitor |
| 2073 |
(R)-(-)-Apomorphine hydrochloride |
| Dopamine agonist; non-subtype-selective |
| 2098 |
Apoptosis Activator 2 |
| Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis |
| 6486 |
Aprepitant |
| Potent long-acting hNK1 antagonist |
| 4139 |
Aprotinin |
| Competitive serine protease inhibitor |
| 2756 |
Arachidonic acid (in Tocrisolve™100) |
| Endogenous free fatty acid (in water-soluble emulsion) |
| 2836 |
Arachidonyl serotonin |
| Dual FAAH inhibitor/TRPV1 antagonist |
| 1814 |
N-ArachidonylGABA |
| Inhibits pain in vivo |
| 1298 |
2-Arachidonylglycerol |
| Endogenous and non-selective CB agonist; potent GPR55 agonist |
| 1445 |
N-Arachidonylglycine |
| GPR18 agonist; endocannabinoid |
| 7235 |
Arbidol New |
| Broad spectrum antiviral |
| 0389 |
Arcaine sulfate |
| Competitive NMDA antagonist |
| 1777 |
Arctigenin |
| Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation |
| 2457 |
Arcyriaflavin A |
| Potent cdk4 inhibitor; also potently inhibits CaM kinase II; antiviral |
| 0383 |
Arecaidine propargyl ester tosylate |
| Muscarinic agonist |
| 6219 |
Arformoterol tartrate |
| Long-acting β2 agonist (LABA) |
| 1637 |
Argatroban |
| Potent thrombin inhibitor |
| 0663 |
L-Arginine |
| Endogenous substrate for NOS |
| 5584 |
Aripiprazole |
| High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist |
| 6818 |
Artemether |
| Antimalarial; also inhibits neuroinflammation |
| 2668 |
Artemisinin |
| Antimalarial; inhibits P-type ATPase (PfATP6) of P.falciparum |
| 6827 |
Artesunate |
| Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial |
| 1354 |
Arvanil |
| Potent CB1 agonist; also anandamide transport inhibitor and TRPV1 agonist |
| 4210 |
Ascomycin |
| Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631) |
| 4055 |
L-Ascorbic acid |
| Enhances the generation of iPSCs; increases reprogramming efficiency |
| 3737 |
Asenapine maleate |
| Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent |
| 0213 |
D-Aspartic acid |
| NMDA agonist |
| 0214 |
L-Aspartic acid |
| NMDA agonist |
| 4092 |
Aspirin |
| Cyclooxygenase inhibitor; NSAID |
| 3489 |
Astemizole |
| Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker |
| 1606 |
Astressin |
| Potent CRF antagonist |
| 2391 |
Astressin 2B |
| Selective CRF2 antagonist |
| 0387 |
(RS)-Atenolol |
| β1 antagonist |
| 2937 |
Atipamezole hydrochloride |
| Selective α2 antagonist |
| 4580 |
Atiprimod dihydrochloride |
| JAK2 inhibitor |
| 3776 |
Atorvastatin hemicalcium salt |
| Potent HMG-CoA reductase inhibitor |
| 6332 |
Atosiban |
| Potent oxytocin receptor antagonist |
| 6358 |
Atovaquone |
| Inhibits complex III of mitochondrial electron transport chain in parasites |
| 1912 |
Atrial natriuretic factor (1-28) (rat) |
| Endogenous peptide regulating blood pressure |
| 1906 |
Atrial natriuretic factor (1-28) (human, porcine) |
| Endogenous peptide regulating blood pressure |
| 4600 |
Auranofin |
| Thioredoxin reductase inhibitor; induces MPT |
| 1688 |
Autocamtide-2-related inhibitory peptide |
| Selective CaM kinase II inhibitor |
| 5959 |
Autocamtide-2-related inhibitory peptide, myristoylated |
| CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide |
| 6324 |
Autophinib |
| Potent VPS34 inhibitor |
| 6834 |
Auxin |
| Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone |
| 6363 |
Avagacestat |
| Highly potent γ-secretase inhibitor; orally bioavailable |
| 6505 |
Avasimibe |
| ACAT inhibitor |
| 4350 |
Axitinib |
| Potent VEGFR-1, -2 and -3 inhibitor |
| 6868 |
8-Azaadenosine |
| ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor; inhibits leukemia stem cell self-renewal |
| 3842 |
5-Azacytidine |
| DNA methyltransferase inhibitor |
| 4099 |
Azathioprine |
| Purine analog; prodrug of 6-mercaptopurine (Cat. No. 4103) |
| 6584 |
L-Azidohomoalanine hydrochloride |
| Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins |
| 6585 |
L-Azidonorleucine hydrochloride |
| Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins |
| 4150 |
Azidothymidine |
| Selective reverse transcriptase inhibitor; antiretroviral |
| 4553 |
Azilsartan |
| Potent AT1 inverse agonist; antihypertensive |
| 6318 |
Azimilide dihydrochloride |
| Kv11.1 (hERG) channel blocker |
| 3771 |
Azithromycin |
| Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation |
| 5796 |
Azoramide |
| Unfolded protein response (UPR) modulator |