Atrial natriuretic factor (1-28) (rat)

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Cat.No. 1912 - Atrial Natriuretic Factor (1-28) (rat) | Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge: 7 - 23) | CAS No. 88898-17-3
Description: Endogenous peptide regulating blood pressure
Alternative Names: Atrial Natriuretic Peptide (1-28) (rat)
Datasheet
Citations
Reviews (1)
Literature

Biological Activity

Endogenous peptide produced by the heart; involved in blood pressure regulation. Produces natriuresis, diuresis and vasorelaxation in vivo.

Technical Data

M. Wt 3062.43
Formula C128H205N45O39S2
Sequence SLRRSSCFGGRIDRIGAQSGLGCNSFRY

(Modifications: Disulfide bridge between 7 - 23)

Storage Desiccate at -20°C
CAS Number 88898-17-3
PubChem ID 16166338
InChI Key QGFSVPWZEPKNDV-BRTFOEFASA-N
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Atlas et al (1985) Atrial natriuretic factor (auriculin): structure and biological effects. J.Clin.Hypertens. 1 187 PMID: 2941526

de Bold et al (1985) Atrial natriuretic factor: a hormone produced by the heart. Science 230 767 PMID: 2932797

Rubattu and Volpe (2001) The atrial natriuretic peptide: a changing view. J.Hypertens. 19 1923 PMID: 11677356


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Keywords: Atrial Natriuretic Factor (1-28) (rat), Atrial Natriuretic Factor (1-28) (rat) supplier, Endogenous, peptide, regulating, blood, pressure, ANP, Receptors, Atrial, Natriuretic, Peptide, NPR, (1-28), (rat), Receptor, 1912, Tocris Bioscience

Citations for Atrial natriuretic factor (1-28) (rat)

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NP in vitro
By Anonymous on 08/05/2018
Assay Type: In Vitro
Species: Rat

Used in vitro to investigate different roles of NP family members.


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Cardiovascular

Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
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  • Arrhythmias
  • Heart Failure