You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Highly potent PAK1 and PAK2 inhibitor (IC50 values are 0.33 and 6 nM for PAK1 and PAK2, respectively). Displays >7500-fold selectivity for PAK1 over PAK4 (IC50 = 2.6 μM).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|ethanol||12.6||20 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 629.75. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.59 mL||7.94 mL||15.88 mL|
|5 mM||0.32 mL||1.59 mL||3.18 mL|
|10 mM||0.16 mL||0.79 mL||1.59 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
References are publications that support the biological activity of the product.
McCoull et al (2016) Optimization of highly kinase selective bis-anilino pyrimidine PAK1 inhibitors. ACS Med.Chem.Lett. 7 1118 PMID: 27994749
If you know of a relevant reference for AZ 13705339, please let us know.
View Related Products by Product Action
Keywords: AZ 13705339, AZ 13705339 supplier, AZ13705339, PAK1, PAK2, Group, I, inhibitors, inhibits, P21, activated, kinase, highly, potent, P21-activated, Kinases, 6177, Tocris Bioscience
Citations for AZ 13705339
Citations are publications that use Tocris products.
Currently there are no citations for AZ 13705339. Do you know of a great paper that uses AZ 13705339 from Tocris? Please let us know.
Reviews for AZ 13705339
Average Rating: (Based on 1 Review.)
Have you used AZ 13705339?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.