DNA polymerase α, δ and ε inhibitor. Exhibits selectivity over DNA polymerase β and γ. Antimitotic, antibiotic and antiviral.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 338.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.25 mM||11.82 mL||59.09 mL||118.18 mL|
|1.25 mM||2.36 mL||11.82 mL||23.64 mL|
|2.5 mM||1.18 mL||5.91 mL||11.82 mL|
|12.5 mM||0.24 mL||1.18 mL||2.36 mL|
References are publications that support the biological activity of the product.
Spadari et al (1984) Control of DNA replication and cell proliferation in eukaryotes by aphidicolin. Toxicol.Pathol. 12 143 PMID: 11478315
Bucknall et al (1973) Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola. Antimicrob.Agents Chemother. 4 294 PMID: 4357181
Syväoja et al (1990) DNA polymerases α, δ, and ε: three distinct enzymes from HeLa cells. Proc.Natl.Acad.Sci.U.S.A. 87 6664 PMID: 1975694
If you know of a relevant reference for Aphidicolin, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Aphidicolin, Aphidicolin supplier, DNA, polymerase, alpha, α, delta, δ, epsilon, ε, inhibitors, inhibits, antimitotic, antibiotic, antiviral, RNA/DNA, Polymerase, DNA,, RNA, and, Protein, Synthesis, Antibiotics, Antivirals, Mitosis, 5736, Tocris Bioscience
Citations for Aphidicolin
Citations are publications that use Tocris products.
Currently there are no citations for Aphidicolin. Do you know of a great paper that uses Aphidicolin from Tocris? Please let us know.
Reviews for Aphidicolin
There are currently no reviews for this product. Be the first to review Aphidicolin and earn rewards!
Have you used Aphidicolin?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Epigenetics Scientific Review
Written by Susanne Müller-Knapp and Peter J. Brown, this review gives an overview of the development of chemical probes for epigenetic targets, as well as the impact of these tool compounds being made available to the scientific community. In addition, their biological effects are also discussed. Epigenetic compounds available from Tocris are listed.