Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 529.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.89 mL||9.44 mL||18.87 mL|
|5 mM||0.38 mL||1.89 mL||3.77 mL|
|10 mM||0.19 mL||0.94 mL||1.89 mL|
|50 mM||0.04 mL||0.19 mL||0.38 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID: 2412134
Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID: 4326768
Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231 PMID: 7805625
If you know of a relevant reference for AMP PNP, please let us know.
View Related Products by Product Action
Keywords: AMP PNP, supplier, AMPPNP, non-hydrolyzable, non-hydrolysable, AMP, analog, adenylyl-imidodiphosphate, tetralithium, salt, Kir6, channel, blockers, blocks, KATP, inward, rectifier, potassium, current, Inward, rectifier, Potassium, Channels, Tocris Bioscience
Citations for AMP PNP
Citations are publications that use Tocris products.
Currently there are no citations for AMP PNP. Do you know of a great paper that uses AMP PNP from Tocris? If so please let us know.