You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Acetazolamide
Acetazolamide is a carbonic anhydrase inhibitor. Modulates epileptiform synchronization in rat brain slices. Increases speed of synaptic vesicle recycling and changes synaptic performance in ex vivo murine neuromuscular junction. Lowers intracranial pressure in healthy rats. Also potentiates the antitumor effects of the HDAC inhibitor MS 275 (Cat. No. 6208).
Compound Libraries for Acetazolamide
Technical Data for Acetazolamide
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Acetazolamide
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Acetazolamide
The following data is based on the product molecular weight 222.25. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.5 mL||22.5 mL||44.99 mL|
|5 mM||0.9 mL||4.5 mL||9 mL|
|10 mM||0.45 mL||2.25 mL||4.5 mL|
|50 mM||0.09 mL||0.45 mL||0.9 mL|
References for Acetazolamide
References are publications that support the biological activity of the product.
Bayat et al (2017) Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 17 156 PMID: 28235409
Uldall et al (2017) Acetazolamide lowers intracranial pressure and modulates the cerebrospinal fluid secretion pathway in healthy rats. Neurosci.Lett. 645 33 PMID: 28219789
Bertone et al (2017) Carbonic anhydrase inhibitor acetazol. shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction. Synapse. 71 PMID: 28873252
Hamidi (2015) Carbonic anhydrase inhibition by acetazol. reduces in vitro epileptiform synchronization. Neuropharmacology. 95 377 PMID: 25937211
If you know of a relevant reference for Acetazolamide, please let us know.
View Related Products by Product Action
Keywords: Acetazolamide, Acetazolamide supplier, Diamox, carbonic, anhydrase, inhibitors, inhibits, lowers, intracranial, pressure, Carbonic, anhydrases, 6742, Tocris Bioscience
Citations for Acetazolamide
Citations are publications that use Tocris products.
Currently there are no citations for Acetazolamide. Do you know of a great paper that uses Acetazolamide from Tocris? Please let us know.
Reviews for Acetazolamide
There are currently no reviews for this product. Be the first to review Acetazolamide and earn rewards!
Have you used Acetazolamide?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Metabolism Research Product GuideNew
This product guide reviews some of the main areas in cancer metabolism research and lists around 150 products that can be used to investigate metabolic pathways in cancer including:
- Tricarboxylic Acid Cycle
- 1C Metabolism and Nucleic Acid Synthesis
- Drivers of Metabolic Reprogramming
- pH and Redox Balance