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Displaying Products Alphabetically by Name (D)

Cat. No. Product Name / Activity
6582 D-3
Selective PSC eliminating agent
1643 D-64131
Tubulin polymerization inhibitor. Antitumor in vivo
2902 D 4476
Selective CK1 inhibitor. Also inhibits TGF-βRI
1437 D609
Selective PC-PLC inhibitor
5921 D9
Potent thioredoxin reductase (TrxR) inhibitor
3790 DADLE
Prototypical δ agonist
1171 DAMGO
Selective μ agonist
0482 4-DAMP
Muscarinic M3 antagonist
5748 DAPI
Fluorescent DNA stain
1458 DAPK Substrate Peptide
Death associated protein kinase substrate (synthetic)
2634 DAPT
γ-secretase inhibitor; induces neuronal differentiation
2423 DAPTA
Chemokine receptor 5 (CCR5) antagonist
2096 DAU 5884 hydrochloride
M3 receptor antagonist
6175 DBHDA
Reagent for synthetic biology; converts cysteine to dehydroalanine
5095 DBM 1285 dihydrochloride
p38 MAPK inhibitor; anti-inflammatory
4489 DBZ
γ-secretase inhibitor; inhibits Notch pathway
4417 DBeQ
Selective and reversible p97 ATPase inhibitor
5357 DC 260126
FFA1 (GPR40) antagonist
6873 DC 271
Fluorescent retinoic acid analog; solvochromatic probe
2755 DCA
Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor
1952 DCB
Allosteric modulator of mGlu5 receptors
1422 DCEBIO
Activates Cl- conductance and hKCa3.1 channels
0975 DCG IV
Highly potent group II mGlu agonist; also NMDA agonist
2137 2,3-DCPE hydrochloride
Selectively induces cancer cell apoptosis
1395 (R)-3,4-DCPG
AMPA antagonist/weak NMDA antagonist
1394 (RS)-3,4-DCPG
Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
1302 (S)-3,4-DCPG
Potent and selective mGlu8a agonist
1540 DCPIB
Blocker of VRAC/ICl, swell
7160 DD 03-171
Potent and selective BTK Degrader
5077 DDR1-IN-1 dihydrochloride
Selective DDR1 inhibitor
1485 DEA
Endogenous CB1 agonist
2558 10-DEBC hydrochloride
Selective Akt/PKB inhibitor
5774 DEL 22379
ERK dimerization inhibitor
6077 DETA NONOate
Nitric oxide donor
2166 Z-DEVD-FMK
Cell-permeable, irreversible caspase-3 inhibitor
1625 DFB
Positive allosteric modulator of mGlu5 receptors
5609 DFHBI
GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers
5610 DFHBI 1T
GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers
6434 DFHO
RFP fluorophore mimic for imaging RNA in living cells; activated by binding Corn aptamers
2761 DFMO
Ornithine decarboxylase inhibitor
6240 DG 041
Potent and selective EP3 antagonist; antiplatelet and antithrombotic
5566 DG 172 dihydrochloride
Potent PPARβ/δ inverse agonist; promotes BMC differentiation
0112 γDGG
Broad spectrum glutamatergic antagonist
1218 DH 97
MT2 receptor antagonist
4599 3,5-DHBA
Selective HCA1 agonist
0839 DHBP dibromide
Ca2+ release inhibitor
0342 (RS)-3,5-DHPG
Selective group I mGlu agonist
0805 (S)-3,5-DHPG
Selective group I mGlu agonist; active enantiomer of 3,5-DHPG (Cat. No. 0342)
4523 DIDS
Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor
4502 DIM
Inhibits EGFR activation; also induces apoptosis
6376 DIM-C-pPhOCH3
Nur77 agonist
6377 DIM-C-pPhOH
Nur77 antagonist
0794 DIPPA hydrochloride
Selective and irreversible κ antagonist
5884 DIPSO
Buffering agents
6645 DJ-V 159
GPRC6A agonist
7082 DL 175
Potent and selective GPR84 agonist
3154 DL-Dithiothreitol
Maintains SH groups in the reduced state
2241 DMAB-anabaseine dihydrochloride
Partial agonist at α7 nAChR; also α4β2 antagonist
2610 17-DMAG hydrochloride
Water-soluble Hsp90 inhibitor
3083 DMCM hydrochloride
Benzodiazepine inverse agonist
4512 DMF
Nrf2 pathway activator; neuroprotective
4126 DMH-1
Selective ALK2 inhibitor
5580 DMH2
Type I BMP receptor inhibitor
4471 DMH4
Selective VEGFR-2 inhibitor
1481 (-)-5'-DMH-CBD
Metabolically stable anandamide transport inhibitor
2088 DMNB
DNA-PK inhibitor
6315 DMNB-caged-Serine
Caged serine; excited by visible blue light
5948 DMNPE-4 AM-caged-calcium
Caged calcium; cell permeable
5157 DMNPE-caged ATP diammonium salt
Caged ATP
4408 DMOG
Prolyl hydroxylase inhibitor
2330 DMP 543
Potent, orally active ACh release enhancer
3415 DMPO
Nitric oxide spin trap; measure oxygen-centered free radicals
1222 DMPQ dihydrochloride
Potent, selective inhibitor of PDGFRβ
3176 DMSO, sterile filtered
Solvent
5601 DMXAA
mSTING agonist; induces antitumor immunological responses
1953 DMeOB
Negative allosteric modulator of mGlu5 receptors
0189 DNQX
Selective non-NMDA iGluR antagonist
2312 DNQX disodium salt
Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)
2643 DOI hydrochloride
5-HT2A and 5-HT2C agonist
5487 DPC AJ1951
Potent parathyroid hormone (PTH) receptor agonist
0439 DPCPX
Selective A1 antagonist
1431 DPDPE
Selective δ agonist
1494 DPN
Highly potent ERβ agonist
4494 (R)-DPN
Enantiomer of DPN (Cat. No. 1494)
6706 DPNB-ABT 594
Caged ABT 594; suitable for one- or two-photon photolysis
2533 DPO-1
Blocker of KV1.5 channel and IKur current
0743 DPPE fumarate
Inhibitor of histamine binding at the intracellular binding site
2783 DPPI 1c hydrochloride
Dipeptidyl peptidase IV (DPP-IV) inhibitor
6903 DPTIP
Potent and selective N-SMase2 inhibitor; brain penetrant
4491 DQP 1105
GluN2C/GluN2D-selective NMDA antagonist
2496 DR 2313
PARP-1 and PARP-2 inhibitor
5005 DR 4485 hydrochloride
High affinity and selective 5-HT7 antagonist; orally bioavailable
5548 DREADD agonist 21
Potent muscarinic DREADD agonist
6422 DREADD agonist 21 dihydrochloride
Potent muscarinic DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
3610 (R)-DRF053 dihydrochloride
Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
3679 DS2
Positive allosteric modulator of GABAA receptors; displays subunit selectivity
2958 DSP-4
Adrenergic neurotoxin
4809 DSR 6434
Potent TLR7 agonist
0841 DTG
High affinity ligand (σ1 = σ2)
4480 DV 7028 hydrochloride
Selective 5-HT2A antagonist; antithrombotic
5656 DY 268
Potent FXR antagonist
2266 DY131
Agonist selective for estrogen-related receptors ERRβ and ERRγ
7223 Dabrafenib mesylate
Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome
6231 Dacomitinib
Potent irreversible pan ErbB inhibitor
1417 Daidzein
Arrests cell cycle in G1 phase
4684 Daminozide
Selective KDM2/7 inhibitor
1936 Damnacanthal
Potent, selective p56lck inhibitor; also LIMK1/2 inhibitor
5122 Dansyl-NECA
Potent and selective fluorescent adenosine A1 agonist
0507 Dantrolene, sodium salt
Ca2+ release inhibitor
6902 Dapansutrile
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
4358 Dapoxetine hydrochloride
Selective serotonin reuptake inhibitor (SSRI)
3917 Daptomycin
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
6755 Darapladib
Potent lp-PLA2 inhibitor
6710 Darunavir
Highly potent HIV protease inhibitor
6793 Dasatinib
Highly potent pan-Src/Bcr-Abl inhibitor
1467 Daunorubicin hydrochloride
DNA topoisomerase II inhibitor
6779 Davunetide
Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo
4488 1-Deazaadenosine
Adenosine deaminase inhibitor
4703 3-Deazaneplanocin A hydrochloride
EZH2 histone methyltransferase inhibitor
3501 Decanoyl-RVKR-CMK
Subtilisin/Kex2p-like proprotein convertase inhibitor
0477 (±)-Decanoylcarnitine chloride
Intermediate in lipid metabolism
2624 Decitabine
DNA methyltransferase inhibitor
4722 Decynium 22
PMAT inhibitor
5764 Deferoxamine mesylate
Iron chelator; also hypoxia mimetic and neuroprotectant
1770 Deguelin
Anticancer and antiviral agent; chemopreventive and pro-apoptotic
5734 L-Dehydroascorbic acid
GLUT1 substrate; oxidized form of L-Ascorbic acid
4149 Delavirdine mesylate
Non-nucleoside reverse transcriptase inhibitor
5424 Deltarasin
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ
4591 Deltorphin I
Potent δ agonist
1180 [D-Ala2]-Deltorphin II
Selective δ agonist peptide
1819 Demethylasterriquinone B1
Selective insulin RTK activator
4515 2-Deoxy-D-glucose
Non-metabolizable glucose analog; hexokinase substrate
1259 1-Deoxymannojirimycin hydrochloride
α-Mannosidase I inhibitor
3976 Deoxynivalenol
Mycotoxin; potent protein synthesis inhibitor
1258 1-Deoxynojirimycin
Glucosidase I and II inhibitor
1095 (R)-(-)-Deprenyl hydrochloride
MAO-B inhibitor
3328 Desformylflustrabromine hydrochloride
Positive allosteric modulator of α4β2 nAChRs; also muscle-type nAChR inhibitor
3067 Desipramine hydrochloride
Selective inhibitor of noradrenalin transporters
5958 Desloratadine
High affinity H1 antagonist; anti-inflammatory
1007 N-Desmethylclozapine
5-HT2C antagonist
3396 Desmopressin
Synthetic vasopressin analog; V1B and V2 agonist
2304 Devazepide
Selective, orally active CCK1 receptor antagonist
1126 Dexamethasone
Anti-inflammatory glucocorticoid
2695 Dexfenfluramine hydrochloride
5-HT reuptake inhibitor; also stimulates 5-HT release
2749 Dexmedetomidine hydrochloride
Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)
3857 Dexrazoxane hydrochloride
Topoisomerase II inhibitor
5702 DiD perchlorate
Lipophilic fluorescent dye; shown to stain HSCs
6882 DiFMUP
Fluorescent phosphatase substrate
4628 DiMNF
Selective aryl hydrocarbon receptor modulator (SAhRM)
0476 2,4-Diamino-6-hydroxypyrimidine
Inhibits tetrahydrobiopterin synthesis and thus NOS activity
5557 Dianicline
Selective α4β2 nAChR partial agonist
2805 Diazepam
Acts at the benzodiazepine modulatory site
0964 Diazoxide
Inhibits AMPA desensitization
3416 Tris DBA
N-myristoyltransferase-1 inhibitor; antiproliferative
1141 Dibutyryl-cAMP, sodium salt
Cell-permeable cAMP analog
0286 5,7-Dichlorokynurenic acid
Potent NMDA antagonist; acts at glycine site
3698 5,7-Dichlorokynurenic acid sodium salt
Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid
4454 Diclofenac sodium salt
Cyclooxygenase inhibitor; NSAID
0468 N1,N11-Diethylnorspermine tetrahydrochloride
Spermine and spermidine acetyltransferase potentiator
0500 N1,N12-Diethylspermine tetrahydrochloride
Polyamine synthase inhibitor
7090 Digoxigenin-11-dUTP
Hapten modified dUTP for ISH
4583 Digoxin
Na+/K+ ATPase inhibitor
0884 Dihydrexidine hydrochloride
Selective D1-like agonist
2349 Dihydro-β-erythroidine hydrobromide
α4β2, muscle type and Torpedo nAChR antagonist
0474 Dihydroergocristine mesylate
α partial agonist
0475 Dihydroergotamine mesylate
α partial agonist; also D2-like partial agonist and 5-HT antagonist
0505 Dihydroergotoxine mesylate
Binds to GABAA receptor Cl- channel; allosteric modulator of benzodiazepine site
0111 Dihydrokainic acid
EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
6277 7α,25-Dihydroxycholesterol
Highly potent GPR183 (EBI2) agonist
3826 7,8-Dihydroxyflavone
TrkB agonist
0481 Dilazep dihydrochloride
Adenosine uptake inhibitor
0685 Diltiazem hydrochloride
CaV1.x blocker
0506 Dimaprit dihydrochloride
Standard H2 selective agonist
3201 Dimebon dihydrochloride
Neuroprotectant; protects against β-amyloid neurotoxicity
1425 (S)-(+)-Dimethindene maleate
Selective M2 antagonist
4027 16,16-Dimethyl Prostaglandin E2
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
5261 Dimethylenastron
Inhibitor of mitotic motor kinesin Eg5
4640 N,N-Dimethylsphingosine
Sphingosine kinase inhibitor
6705 Diminazene aceturate
ASIC blocker; antihyperalgesic
0484 Dioctanoylglycol
Diacylglycerol kinase inhibitor
3072 Diphenhydramine hydrochloride
H1 antagonist
0504 Diphenyleneiodonium chloride
GPR3 agonist; also inhibits NOS and NADPH oxidases
2965 Diprenorphine
Non-selective opioid antagonist
0486 1,3-Dipropyl-8-phenylxanthine
A1 selective antagonist
6019 Diprotin A
Dipeptidyl peptidase IV (DPP-IV) inhibitor
0691 Dipyridamole
Adenosine transport inhibitor
3807 Disulfiram
Reversibly stimulates SERCA Ca2+-ATPase; displays a range of other activities
0515 Dobutamine hydrochloride
α1, β1 and β2 agonist
4056 Docetaxel
Microtubule stabilizer
3687 Docosahexaenoic acid
RXR agonist
3757 Dofetilide
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
3375 Dolastatin 10 trifluoroacetate
Tubulin polymerization inhibitor
0269 Domoic acid
Potent and selective kainate agonist
2536 Domperidone
Peripheral D2-like antagonist
4385 Donepezil hydrochloride
Potent AChE inhibitor
6568 Dooku 1
Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity
3548 Dopamine hydrochloride
Endogenous agonist at dopamine D1-5 receptors
3093 Dorsomorphin dihydrochloride
Potent AMPK inhibitor; also BMP type I receptor inhibitor
2964 Doxazosin mesylate
α1 antagonist
3206 Doxercalciferol
Vitamin D2 analog, VDR agonist
2252 Doxorubicin hydrochloride
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
4090 Doxycycline hyclate
Broad-spectrum MMP inhibitor; tetracycline derivative
5858 Droperidol
D2 antagonist
1430 DuP 697
Cyclooxygenase-2 (COX-2) inhibitor
4798 (S)-Duloxetine hydrochloride
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
1774 Dynamin inhibitory peptide
Dynamin inhibitor
1775 Dynamin inhibitory peptide, myristoylated
Cell-permeable dynamin inhibitor
1776 Dynamin inhibitory peptide, myristoylated (control)
Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)
6896 Dynapyrazole A
Hedgehog signaling inhibitor; dynein inhibitor
6526 Dynarrestin
Inhibitor of Hedgehog (Hh) signaling; inhibits cytoplasmic dynein
2897 Dynasore
Non-competitive dynamin inhibitor
4222 Dynole 34-2
Dynamin I inhibitor
3195 Dynorphin A
Endogenous κ agonist
3196 Dynorphin B
Endogenous κ agonist

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