cAMPS-Sp, triethylammonium salt

Pricing Availability   Qty
Cat.No. 1333 - cAMPS-Sp, triethylammonium salt | C10H12N5O5PS.C6H15N | CAS No. 93602-66-5
Description: Cell-permeable cAMP analog
Chemical Name: (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews
Literature (1)

Biological Activity

Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor.

R-enantiomer also available.

Technical Data

M. Wt 446.46
Formula C10H12N5O5PS.C6H15N
Storage Desiccate at -20°C
Purity ≥98% (HPLC)
CAS Number 93602-66-5
PubChem ID 57369926
InChI Key OXIPZMKSNMRTIV-UHFFFAOYSA-N
Smiles [H][C@@]([C@@](O[C@@H](N3C=NC4=C3N=CN=C4N)[C@@H]2O)([H])CO1)2O[P@]1([S-])=O.CC[NH+](CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 44.65 100

Preparing Stock Solutions

The following data is based on the product molecular weight 446.46. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL
10 mM 0.22 mL 1.12 mL 2.24 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Dostmann et al (1990) Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem. 265 10484 PMID: 2162349

Kawasaki et al (1998) A family of cAMP-binding proteins that directly activate Rap1. Science 282 2275 PMID: 9856955

Lin et al (2006) Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology 51 747 PMID: 16806304

O'Brian et al (1982) A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 21 4371 PMID: 6289880


If you know of a relevant reference for cAMPS-Sp, triethylammonium salt, please let us know.

Keywords: cAMPS-Sp, triethylammonium salt, cAMPS-Sp, triethylammonium salt supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate, Protein, Kinase, A, 1333, Tocris Bioscience

1 Citation for cAMPS-Sp, triethylammonium salt

Citations are publications that use Tocris products. Selected citations for cAMPS-Sp, triethylammonium salt include:

Keng et al (2012) Dual regulation by ethanol of the inhibitory effects of KA on spinal NMDA-induced pressor responses in rats. J Biomed Sci 19 11 PMID: 22300389


Do you know of a great paper that uses cAMPS-Sp, triethylammonium salt from Tocris? Please let us know.

Reviews for cAMPS-Sp, triethylammonium salt

There are currently no reviews for this product. Be the first to review cAMPS-Sp, triethylammonium salt and earn rewards!

Have you used cAMPS-Sp, triethylammonium salt?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis