cAMPS-Sp, triethylammonium salt

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Cat.No. 1333 - cAMPS-Sp, triethylammonium salt | C10H12N5O5PS.C6H15N | CAS No. 93602-66-5
Description: Cell-permeable cAMP analog
Chemical Name: (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
Purity: ≥98% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (1)

Biological Activity

Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor.

R-enantiomer also available.

Technical Data

M. Wt 446.46
Formula C10H12N5O5PS.C6H15N
Storage Desiccate at -20°C
Purity ≥98% (HPLC)
CAS Number 93602-66-5
PubChem ID 57369926
InChI Key OXIPZMKSNMRTIV-UHFFFAOYSA-N
Smiles [H][C@@]([C@@](O[C@@H](N3C=NC4=C3N=CN=C4N)[C@@H]2O)([H])CO1)2O[P@]1([S-])=O.CC[NH+](CC)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 44.65 100

Preparing Stock Solutions

The following data is based on the product molecular weight 446.46. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL
10 mM 0.22 mL 1.12 mL 2.24 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Keywords: cAMPS-Sp, triethylammonium salt, cAMPS-Sp, triethylammonium salt supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate, Protein, Kinase, A, 1333, Tocris Bioscience

2 Citations for cAMPS-Sp, triethylammonium salt

Citations are publications that use Tocris products. Selected citations for cAMPS-Sp, triethylammonium salt include:

Mishra et al (2018) Reactivation of cAMP Pathway by PDE4D Inhibition Represents a Novel Druggable Axis for Overcoming TAX Resistance in ER-positive Breast Cancer. Clin Cancer Res 24 1987 PMID: 29386221

Keng et al (2012) Dual regulation by ethanol of the inhibitory effects of KA on spinal NMDA-induced pressor responses in rats. J Biomed Sci 19 11 PMID: 22300389


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Literature in this Area

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