L-Azidonorleucine hydrochloride

Pricing Availability   Qty
Description: Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins
Chemical Name: (S)-2-Amino-6-azidohexanoic acid hydrochloride
Literature (1)

Biological Activity for L-Azidonorleucine hydrochloride

L-Azidonorleucine hydrochloride is an unnatural amino acid; methionine surrogate. Can be incorporated into proteins by a mutant methionyl tRNA synthetase to enable cell-type specific analysis of protein synthesis. For use with bio-orthogonal non-canonical amino-acid tagging (BONCAT) or fluorescent non-canonical amino acid tagging (FUNCAT). Labeling does not affect the normal localization of the labeled proteins.

Technical Data for L-Azidonorleucine hydrochloride

M. Wt 208.65
Formula C6H12N4O2.HCl
Storage Store at -20°C
CAS Number 1454334-76-9
PubChem ID 121235322
Smiles N[C@H](C(O)=O)CCCCN=[N+]=[N-].Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for L-Azidonorleucine hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
water 20.86 100

Preparing Stock Solutions for L-Azidonorleucine hydrochloride

The following data is based on the product molecular weight 208.65. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.79 mL 23.96 mL 47.93 mL
5 mM 0.96 mL 4.79 mL 9.59 mL
10 mM 0.48 mL 2.4 mL 4.79 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets for L-Azidonorleucine hydrochloride

Certificate of Analysis / Product Datasheet
Select another batch:

References for L-Azidonorleucine hydrochloride

References are publications that support the biological activity of the product.

Alvarez-Castelao et al (2017) Cell-type-specific metabolic labeling of nascent proteomes in vivo. Nat.Biotechnol. 35 1196 PMID: 29106408

Mahdavi et al (2016) Engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis. J.Am.Chem.Soc. 138 4278 PMID: 26991063

If you know of a relevant reference for L-Azidonorleucine hydrochloride, please let us know.

Keywords: L-Azidonorleucine hydrochloride, L-Azidonorleucine hydrochloride supplier, unnatural, amino, acid, UAA, ANL, methionine, surrogate, BONCAT, FUNCAT, bio-orthogonal, fluorescent, non-canonical, tagging, methionyl, tRNA, synthetase, metRS, Biochemicals, and, Molecular, Biology, Unnatural, Amino, Acids, 6585, Tocris Bioscience

Citations for L-Azidonorleucine hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for L-Azidonorleucine hydrochloride. Do you know of a great paper that uses L-Azidonorleucine hydrochloride from Tocris? Please let us know.

Reviews for L-Azidonorleucine hydrochloride

There are currently no reviews for this product. Be the first to review L-Azidonorleucine hydrochloride and earn rewards!

Have you used L-Azidonorleucine hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals