All Products

Displaying Products Alphabetically by Name (S)

Cat. No. Product Name / Activity
5188 S 07662
Constitutive androstane receptor (CAR) inverse agonist
1771 S 14506 hydrochloride
Highly potent 5-HT1A agonist; displays unique binding mechanism
5568 S 18886
Potent thromboxane A2 (TP) antagonist
3911 S 18986
Positive allosteric modulator of AMPA receptors
5714 S 2101
LSD1 inhibitor
3518 S 24795
α7 nAChR partial agonist
3432 S 25585
Potent and selective NPY Y5 receptor antagonist
4508 S 32212 hydrochloride
5-HT2C inverse agonist; α2-adrenoceptor antagonist
3404 S 32826
Potent autotaxin inhibitor
6778 S 38093
Selective H3 antagonist and inverse agonist; also σ1 receptor antagonist; antinociceptive
3690 S26948
Selective PPARγ agonist; antidiabetic agent
5735 S3QEL 2
Suppressor of complex III superoxide production
5577 S4
High affinity and selective CA IX and CA XII inhibitor
4951 SA 4503 dihydrochloride
Selective σ1 receptor agonist
4785 SA 47
Selective FAAH inhibitor
4752 SA 57
Potent FAAH inhibitor
4366 SAG
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
5282 SAG 21k
Hedgehog signaling activator; brain penetrant and orally bioavailable
6390 SAG dihydrochloride
Dihydrochloride salt of SAG; Smo receptor agonist
6708 SAH-EZH2
EZH2/EDD interaction inhibitor; suppresses PCR2 complex function
6920 SAH-SOS1A
KRas/SOS1 interaction inhibitor
4652 SAHA
Class I and II HDAC inhibitor
6477 SAHM1
Notch pathway inhibitor; prevents Notch complex assembly
6239 SAK 3
Potent CaV3.1 and 3.3 activator; orally bioavailable
1344 SAMS Peptide
AMP-activated protein kinase substrate
1974 SANT-1
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
3617 SANT-2
Inhibitor of Hedgehog (Hh) signaling; antagonizes smoothened activity
5650 SAR 216471 hydrochloride
Potent P2Y12 antagonist; orally available
5831 SAR 7334
Potent TRPC6 inhibitor
1371 SB 200646 hydrochloride
5-HT2C/2B antagonist
1264 SB 202190
Potent, selective inhibitor of p38 MAPK
0785 SB 203186 hydrochloride
5-HT4 antagonist
1202 SB 203580
Selective inhibitor of p38 MAPK
1402 SB 203580 hydrochloride
Selective inhibitor of p38 MAPK; water-soluble
1373 SB 204070
Potent and selective 5-HT4 antagonist
1372 SB 204741
Potent, selective 5-HT2B antagonist
4962 SB 204990
ATP citrate lyase (ACLY) inhibitor
1512 SB 205384
GABAA modulator; slows current decay
0921 SB 205607 dihydrobromide
Selective, high affinity non-peptide δ1 agonist
1661 SB 206553 hydrochloride
Potent and selective 5-HT2B and 5-HT2C antagonist; orally active
1242 SB 216641 hydrochloride
Selective h5-HT1B antagonist
1616 SB 216763
Potent, selective GSK-3 inhibitor
2560 SB 218078
Chk1 inhibitor
1376 SB 218795
Potent, selective non-peptide NK3 antagonist
1379 SB 221284
Potent and selective 5-HT2B and 5-HT2C antagonist
1393 SB 222200
Potent, selective non-peptide NK3 antagonist. Brain penetrant
4672 SB 223412
Potent, selective non-peptide NK3 antagonist. Brain penetrant
1221 SB 224289 hydrochloride
Selective 5-HT1B antagonist
2725 SB 225002
Potent and selective CXCR2 antagonist
1375 SB 228357
5-HT2C/2B antagonist/inverse agonist
1962 SB 239063
Potent, selective p38 MAPK inhibitor; orally active
2901 SB 242084
Selective 5-HT2C antagonist; brain penetrant
3527 SB 243213 dihydrochloride
Selective 5-HT2C inverse agonist
1961 SB 258585 hydrochloride
Potent, selective 5-HT6 antagonist
2726 SB 258719 hydrochloride
Selective 5-HT7 antagonist
2724 SB 265610
Potent CXCR2 antagonist
4314 SB 268262
Selective non-peptide CGRP antagonist
1612 SB 269970 hydrochloride
Potent and selective 5-HT7 antagonist; brain penetrant
3368 SB 271046 hydrochloride
Selective 5-HT6 antagonist; orally active
4207 SB 277011A dihydrochloride
Selective D3 antagonist
6860 SB 290157 trifluoroacetate
Potent C3a receptor antagonist
4213 SB 297006
Potent and selective CCR3 antagonist
3650 SB 328437
Potent and selective CCR3 antagonist
5671 SB 332235
Potent CXCR2 antagonist
1960 SB 334867
Selective non-peptide OX1 antagonist
1615 SB 366791
Potent, selective, competitive TRPV1 antagonist
3189 SB 399885 hydrochloride
Potent and selective 5-HT6 antagonist
6088 SB 3CT
High affinity and selective MMP2 inhibitor
6881 SB 4
Potent BMP4 agonist
1963 SB 408124
Selective non-peptide OX1 antagonist
1617 SB 415286
Potent, selective GSK-3 inhibitor
TB1614-GMP SB 431542
SB 431542 synthesized to cGMP guidelines
3265 SB 452533
Potent TRPV1 receptor antagonist
3263 SB 505124
Selective inhibitor of TGF-βRI, ALK4 and ALK7
3211 SB 525334
Selective inhibitor of TGF-βRI
2650 SB 590885
Potent B-Raf inhibitor
4670 SB 611812
Urotensin-II (UT) antagonist; attenuates cardiac dysfunction
3573 SB 612111 hydrochloride
Selective NOP antagonist
3571 SB 657510
Selective urotensin-II (UT) receptor antagonist
4673 SB 674042
Potent and selective non-peptide OX1 antagonist
3188 SB 699551
Selective 5-ht5a antagonist
4667 SB 706375
High affinity, non-peptide UT receptor antagonist
5040 SB 706504
p38 MAPK inhibitor
5109 SB 743921 hydrochloride
Potent kinesin spindle protein (KSP) inhibitor
4630 SB 747651A dihydrochloride
Potent MSK1 inhibitor; also inhibits other AGC group kinases
4118 SB 772077B dihydrochloride
Potent Rho-kinase inhibitor; vasodilator
3810 SBHA
HDAC1/3 inhibitor
7233 SBP1
ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
7232 SBP1-FITC
Fluorescent ACE2-derived peptide; binds receptor binding domain of SARS-CoV-2 spike protein
4963 SC 144 hydrochloride
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
1206 SC 19220
Selective EP1 receptor antagonist
4189 SC 26196
Selective fatty acid desaturase 2 inhibitor
3758 SC 51089
Selective EP1 receptor antagonist
2791 SC 51322
Potent EP1 receptor antagonist
3318 SC 514
IKKβ inhibitor; attenuates NF-κB-induced gene expression
1550 SC 560
Cyclooxygenase-1 (COX-1) inhibitor
3107 SC 57461A
Selective inhibitor of LTA4 hydrolase
2895 SC 58125
Selective cyclooxygenase-2 (COX-2) inhibitor
3919 SC 236
Selective cyclooxygenase-2 (COX-2) inhibitor
4398 SC 66
Allosteric Akt inhibitor
4635 SC 79
Akt activator
0433 SC-9
Protein kinase C activator
1400 SCH 202676 hydrobromide
Inhibitor of ligand binding to G-protein-coupled receptors
3240 SCH 221510
Potent and selective NOP agonist
0925 SCH 23390 hydrochloride
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker
1690 SCH 28080
H+,K+-ATPase inhibitor
5815 SCH 336
Highly potent and selective CB2 inverse agonist
2299 SCH 39166 hydrobromide
High affinity D1-like antagonist
2463 SCH 442416
Very selective, high affinity A2A antagonist
0984 SCH 50911
Selective and competitive GABAB antagonist; orally bioavailable
5280 SCH 51344
Potent MTH1 inhibitor
4240 SCH 529074
Restores mutant p53 activity
2270 SCH 58261
Potent, highly selective A2A antagonist
1592 SCH 79797 dihydrochloride
Potent, selective non-peptide PAR1 antagonist
3528 SCIO 469 hydrochloride
Selective p38 MAPK inhibitor
5342 SCR7 pyrazine
Enhances HDR efficiency
2143 SCS
Potent GABAA antagonist; β1-subunit selective
3035 SD 1008
JAK2/STAT3 signaling pathway inhibitor
3269 SD 208
Potent ATP-competitive TGF-βRI inhibitor
4775 SD 2590 hydrochloride
Potent MMP inhibitor
1410 SDM25N hydrochloride
Potent, selective non-peptide δ antagonist; also inhibits dengue virus replication
2037 SDZ 205-557 hydrochloride
5-HT3 and 5-HT4 antagonist
1516 SDZ 21009
β-adrenoceptor antagonist; also 5-HT1A and 5-HT1B antagonist
1251 SDZ 220-040
Potent competitive NMDA antagonist
1250 SDZ 220-581
Competitive NMDA antagonist
2394 SDZ NKT 343
Highly selective human NK1 antagonist
1255 SDZ SER 082 fumarate
Selective 5-HT2B/2C antagonist
2465 SDZ WAG 994
Potent, selective A1 agonist
6164 SEA 0400
Potent Na+/Ca2+ exchanger (NCX) inhibitor
4441 SEN 12333
α7 nAChR agonist; also histamine H3 antagonist
3556 SER 601
Potent, selective CB2 agonist
2284 SEW 2871
Cell-permeable, selective S1P1 receptor agonist
3898 SF 11
NPY Y2 receptor antagonist
5020 SF 1670
PTPN2 and PTEN inhibitor
6488 5(6)-SFX (Fluorescein), SE
Green fluorescent dye for the labeling of primary amines
4541 SGC 0946
Highly potent and selective DOT1L inhibitor; cell permeable
6825 SGC 3027
Potent and selective PRMT7 inhibitor
6838 SGC 3027N
Negative control for SGC 3027 (Cat. No. 6825)
5367 SGC 707
Potent and selective allosteric inhibitor of PRMT3
6528 SGC AAK1 1
AAK1 and BMP2K inhibitor; activates Wnt signaling
6564 SGC GAK 1
High affinity cyclin G associated kinase (GAK) inhibitor
4889 SGC-CBP30
Potent CBP/p300 BRD inhibitor
5155 SGI 1027
DNA methyltransferase inhibitor
3688 SGS 518 oxalate
Selective 5-HT6 antagonist
5356 SGX 523
Selective and potent c-MET kinase inhibitor
4510 SHA 68
Selective Neuropeptide S receptor antagonist
6998 SHIN 1
Potent SHMT inhibitor
6101 SHIP 2a
Cystathione γ lyase (CSE) inhibitor
3420 SHU 9119
MC3 and MC4 antagonist; MC5 partial agonist
5964 SI-2 hydrochloride
Steroid receptor coactivator 3 (SRC-3) inhibitor
4766 SIB 1508Y maleate
Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors
4764 SIB 1553A hydrochloride
nAChR agonist; displays selectivity for β4 subunit-containing receptors
1215 SIB 1757
Highly selective mGlu5 antagonist
1214 SIB 1893
mGlu5 antagonist; also positive allosteric modulator at mGlu4 receptors
3625 SID 26681509
Cathepsin L inhibitor
3440 SID 7969543
Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor
0756 SIN-1 chloride
Water-soluble NO donor
5291 SIS3
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
3929 SJ 172550
MDMX inhibitor. Disrupts MDMX-p53 interaction
6187 SK 216
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
7039 SK 609
Dopamine D3 receptor biased agonist
1079 (+)-SK&F 10047 hydrochloride
σ1 selective agonist
6398 SKA 121
Positive allosteric modulator of KCa3.1 channels
3670 SKA 31
Activator of KCa3.1 and KCa2 channels
0922 SKF 38393 hydrobromide
Selective D1-like agonist
1662 SKF 77434 hydrobromide
Selective D1-like partial agonist
1447 SKF 81297 hydrobromide
D1 agonist
5719 SKF 82958 hydrobromide
D1 agonist
1586 SKF 83566 hydrobromide
Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2
2075 SKF 83822 hydrobromide
Selective D1-like agonist
2074 SKF 83959 hydrobromide
D1-like partial agonist
2008 SKF 86002 dihydrochloride
p38 MAPK inhibitor; anti-inflammatory agent
3866 SKF 86466 hydrochloride
Potent and selective α2 antagonist
1081 SKF 89976A hydrochloride
Potent GAT-1 inhibitor; brain penetrant
0512 SKF 91488 dihydrochloride
Histamine N-methyltransferase inhibitor
1147 SKF 96365 hydrochloride
TRPC channel blocker; also inhibits store-operated Ca2+ entry
0379 SKF 97541
Highly potent GABAB agonist; also GABAA-ρ antagonist
5452 SKI 178
Non-lipid sphingosine kinase 1 (SphK1) inhibitor
2097 SKI II
Selective non-lipid inhibitor of sphingosine kinase
4817 SKPin C1
Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest
2250 SL 0101-1
Selective ribosomal S6 kinase (RSK) inhibitor
1969 SL 327
Selective inhibitor of MEK1 and MEK2; brain penetrant
3010 SLIGKV-NH2
PAR2 receptor agonist
1468 SLIGRL-NH2
PAR2-activating peptide
6281 SLM 6031434 hydrochloride
Selective sphingosine kinase 2 (Sphk2) inhibitor
4605 (±)-SLV 319
High affinity and selective CB1 antagonist
3344 SLV 320
Potent and selective A1 antagonist
6245 SM 16
Potent TGF-βRI inhibitor; orally bioavailable
5445 SM 324405
Potent TLR7 agonist
0751 SM-21 maleate
Presynaptic cholinergic modulator
4662 SMANT hydrochloride
Inhibits Smoothened (Smo) accumulation
5314 SMBA 1
High affinity and selective activator of Bax
4297 SMER 28
Positive regulator of autophagy
4375 SMER 3
Selective inhibitor of E3 ubiquitin ligase
4401 SMIFH2
FH2 domain inhibitor; prevents actin nucleation
4907 SN 2
Selective TRPML3 channel activator
2684 SN 38
DNA topoisomerase I inhibitor; antitumor
2184 SN-6
Selective Na+/Ca2+ exchange inhibitor (reverse mode)
0598 SNAP
A stable analog of endogenous S-nitroso compounds
2398 SNAP 5089
Subtype-selective α1A antagonist
1561 (S)-SNAP 5114
GABA uptake inhibitor
3347 SNAP 94847 hydrochloride
Potent and selective MCH1 antagonist
1529 SNC 162
Potent, selective non-peptide δ agonist
0764 SNC 80
Highly selective non-peptide δ agonist
0603 SNOG
NO carrier. Breaks down to release NO
4075 SNS 032
Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9
4584 SNS 314 mesylate
Potent pan-Aurora kinase inhibitor
2945 SNX 482
Potent and selective CaV2.3 blocker
5309 SP 100030
NF-κB and AP-1 dual inhibitor
5332 SP 141
High affinity MDM2 inhibitor
1496 SP 600125
Selective JNK inhibitor
5809 SPL 334
S-Nitrosoglutathione reductase inhibitor
5391 SPP 86
Potent RET inhibitor
6597 SPRi 3
Potent sepiapterin reductase (SPR) inhibitor; attenuates proliferation of CD4+ T cells
6055 SPT Imidazopyridine 1
Potent serine palmitoyl transferase inhibitor
1435 SQ 22536
Adenylyl cyclase inhibitor
5868 SR 0987
T cell-specific RORγ (RORγt) agonist
4868 SR 1001
RORα/γ inverse agonist
6038 SR 10067
Selective Rev-Erbα/β agonist; anxiolytic
4874 SR 1078
RORα/γ agonist
3411 SR 11237
Pan RXR agonist
2476 SR 11302
AP-1 inhibitor; antitumor agent
2969 SR 12813
Pregnane X receptor agonist
5431 SR 13800
Potent MCT1 inhibitor
4012 SR 140333
Potent NK1 antagonist
0923 SR 141716A
Selective CB1 inverse agonist
2309 SR 142948
Highly potent NTS receptor antagonist
5039 SR 144528
High affinity and selective CB2 inverse agonist
4424 SR 16584
Selective α3β4 nAChR antagonist
4409 SR 1664
High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation
6383 SR 16832
Dual site PPARγ inhibitor
2022 SR 202
Selective PPARγ antagonist; antidiabetic and antiobesity agent
4869 SR 2211
Selective RORγ inverse agonist
1804 SR 2640 hydrochloride
Potent, selective LTD4 /LTE4 receptor antagonist
2190 SR 27897
Potent and selective CCK1 antagonist
5767 SR 3029
Potent and selective CK1δ and CK1ε inhibitor
1806 SR 33805 oxalate
CaV1.x blocker; binds allosterically to distinct site
5044 SR 3576
Highly potent and selective JNK3 inhibitor
3667 SR 3677 dihydrochloride
Potent, selective Rho-kinase (ROCK) inhibitor
3721 SR 48692
Selective non-peptide NTS1 antagonist
2310 SR 49059
Selective, orally active vasopressin V1A receptor antagonist
1205 SR 57227 hydrochloride
Potent and selective 5-HT3 agonist
3986 SR 58611A hydrochloride
β3 agonist; displays anxiolytic and antidepressant effects
1511 SR 59230A hydrochloride
Potent and selective β3 antagonist
5626 SR 7826
Potent and selective LIMK inhibitor; antitumor
4463 SR 8278
Rev-Erbα antagonist
5855 SR 9009
Rev-Erbα/β agonist
5854 SR 9238
Potent and selective LXR inverse agonist
6138 SR 9243
Selective LXR inverse agonist
1262 SR 95531 hydrobromide
Competitive and selective GABAA antagonist
5063 SRPIN340
Selective SRPK1 inhibitor
5253 SSM 3 trifluoroacetate
Potent furin inhibitor
3297 SSR 146977 hydrochloride
Potent and selective NK3 antagonist
6195 SSR 149415
Potent and selective vasopressin V1B antagonist
5559 SSR 180711 hydrochloride
Selective α7 nAChR partial agonist
2506 SSR 69071
Potent, orally active human leukocyte elastase inhibitor
6271 ST 034307
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
6775 ST 045849
O-GlcNAc transferase (OGT) inhibitor
4337 ST 1936 oxalate
Selective, high affinity 5-HT6 agonist
2638 ST 91
α2 agonist, putative α2C agonist
6566 STAD 2
AKAP disruptor; selectively binds PKA-RII and blocks its interaction with AKAP; cell permeable
2204 STEARDA
Endogenous lipid, active in vivo. Enhances effects of endovanilloids at TRPV1 receptors
4509 STF 083010
Inhibits IRE1α endonuclease activity
5207 STF 118804
NAMPT inhibitor; depletes leukemia stem cells
4484 STF 31
NAMPT inhibitor; also GLUT1 inhibitor
6036 STK16-IN-1
Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases
1551 STO-609 acetate
Selective CaM kinase kinase inhibitor
5570 STOCK2S 26016
Lysine deficient protein kinase (WNK) signaling inhibitor
3304 SU 16f
Potent and selective PDGFRβ inhibitor
3607 SU 3327
Selective JNK inhibitor
1459 SU 4312
Potent inhibitor of VEGFR tyrosine kinase
3300 SU 5402
Potent FGFR and VEGFR inhibitor
3037 SU 5416
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
6475 SU 6656
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
3335 SU 6668
PDGFR, VEGFR and FGFR inhibitor
2907 SU 9516
Cdk inhibitor; potently inhibits cdk1 and cdk2
4826 SUN 11602
Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
2550 SUN-B 8155
Non-peptide calcitonin agonist
5759 SW 033291
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
3639 SX 011
p38 MAPK inhibitor
0903 SYM 2081
Highly selective kainate agonist
0961 SYM 2206
Non-competitive AMPA antagonist
5076 SZL P1-41
Selective Skp2 inhibitor; suppresses E3 ligase activity
0246 Saclofen
Selective GABAB antagonist
5772 Sacubitril calcium
Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
3657 Sal 003
Cell-permeable inhibitor of eIF2α dephosphorylation
0634 Salbutamol hemisulfate
β agonist (β2 > β1)
4127 Salermide
SIRT1 and SIRT2 inhibitor
3637 Salinomycin sodium salt
Antibiotic; also selectively inhibits cancer stem cells
4989 Salirasib
Ras inhibitor; also induces autophagy
4712 Salmeterol xinafoate
Long-acting β2 agonist; bronchodilator
0636 Salsolinol-1-carboxylic acid
Endogenous amino acid
2347 Salubrinal
Selective inhibitor of eIF2α dephosphorylation
2134 Salvinorin A
Highly potent and selective κ agonist
5611 Salvinorin B
Activates the κ-opioid DREADD (KORD)
2302 Sanguinarine chloride
Inhibitor of protein phosphatase 2C (PP2C)
4418 Saquinavir mesylate
HIV protease inhibitor
7189 Saracatinib
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
1899 Sarafotoxin S6a
Endothelin receptor agonist
1175 Sarafotoxin S6c
Selective ETB agonist
2975 Sarcosine
GlyT1 inhibitor
3739 Sarpogrelate hydrochloride
Selective 5-HT2A antagonist
1609 Sauvagine
CRF agonist
6507 Saxagliptin hydrochloride
High affinity DPP-IV inhibitor; active in vivo
2736 Sazetidine A dihydrochloride
α4β2 nAChR ligand; may act as an agonist or a desensitizer
1414 Scopolamine hydrobromide
Non-selective muscarinic antagonist
2421 Scriptaid
Histone deacetylase inhibitor
2849 SecinH3
Sec7-specific GEF inhibitor; selective for cytohesin family
1918 Secretin (human)
Gastrointestinal peptide
1919 Secretin (rat)
Gastrointestinal peptide
1836 Seglitide
sst2 and sst5 agonist
3351 Selexipag
Selective prostacyclin IP1 receptor agonist
6815 Selumetinib
Potent and selective MEK inhibitor; orally bioavailable
4875 Senexin A
Cdk8 inhibitor
1068 Senktide
Tachykinin NK3 agonist
5553 Sephin 1
Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
0226 D-Serine
Potentiator of NMDA recepors; acts at glycine site
0227 L-Serine
Weak endogenous glycine receptor agonist
3547 Serotonin hydrochloride
Endogenous 5-HT receptor agonist
2395 Sertraline hydrochloride
5-HT reuptake inhibitor
3220 ShK-Dap22
Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro
6829 (R)-Shikonin
PTEN inhibitor; induces necroptosis; anti-inflammatory
4923 Shz 1
Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs
2290 Sibutramine hydrochloride
5-HT and NA reuptake inhibitor (SNRI)
1148 Siguazodan
PDE3 inhibitor
3784 Sildenafil citrate
Potent PDE5 inhibitor; orally active
6663 Silodosin
Selective α1A antagonist
1965 Simvastatin
HMG-CoA reductase inhibitor
3848 Sinomenine hydrochloride
Anti-inflammatory; causes mast cell degranulation and histamine release
4044 Sipatrigine
NaV blocker; neuroprotective
5457 SirReal 2
Selective inhibitor of SIRT2
6740 Siramesine hydrochloride
High affinity σ agonist (σ2 > σ1)
3521 Sirtinol
Selective sirtuin family deacetylase inhibitor
6816 Sitagliptin phosphate
Potent and selective DPP IV inhibitor
3535 Sivelestat sodium salt
Selective leukocyte elastase inhibitor
6424 Sodium Cromoglicate
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
3159 Sodium acetate
Commonly used laboratory reagent
3152 Sodium bicarbonate
Commonly used laboratory reagent
3850 Sodium butyrate
Histone deacetylase inhibitor
3146 Sodium chloride
Commonly used laboratory reagent
3161 Sodium citrate
Commonly used laboratory reagent
3166 Sodium dodecyl sulphate solution
Detergent used in electrophoresis of proteins
2821 Sodium orthovanadate
Protein tyrosine phosphatase inhibitor
3153 Sodium phosphate dibasic
Commonly used in biological assay buffers
5226 Sodium phosphate monobasic
Commonly used in biological assay buffers
1157 Somatostatin
Influences growth hormone release
1165 Somatostatin 1-28
sst agonist
4185 Sonepiprazole
Selective D4 antagonist
6814 Sorafenib
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
7119 Sorbic acid
Activator of hFFA2-DREADDs
0952 Sotalol hydrochloride
β antagonist
5594 Spadin
Potent K2P2.1 (TREK-1) channel blocker
0391 Spaglumic acid
Selective mGlu3 agonist
1784 Spantide I
Selective NK1 antagonist
5197 Spautin 1
USP10 and USP13 inhibitor; inhibits autophagy
0958 Spermine tetrahydrochloride
Modulator at polyamine site
6090 Spexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivo
0633 D-erythro-Sphingosine (synthetic)
Protein kinase C inhibitor
1370 Sphingosine-1-phosphate
Endogenous agonist at S1P1-5
4729 α-Spinasterol
TRPV1 antagonist; active in vivo
2931 Spinorphin
Enkephalin-degrading and ACE inhibitor
0995 Spiperone hydrochloride
5-HT2A antagonist; also D2-like antagonist
2968 Spironolactone
Mineralocorticoid receptor antagonist
0631 Spiroxatrine
Potent α2C antagonist
1542 Splitomicin
Sir2p inhibitor
6364 Squarunkin A hydrochloride
UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation
3642 Src I1
Dual site Src kinase inhibitor
6575 StRIP16
Rab8a GTPase-binding stapled peptide
2798 Stattic
Selective STAT3 inhibitor
3741 Stauprimide
Inhibits NME2 nuclear translocation; primes ESCs for differentiation
1285 Staurosporine
Non-selective protein kinase inhibitor
4990 Stavudine
Nucleoside analog; antiviral
1621 Streptozocin
DNA alkylator; antitumor and induces diabetes
1608 Stressin I
CRF1 agonist
4749 Strontium chloride
Calcium sensing receptor (CaSR) agonist
1156 Substance P
Sensory neuropeptide; inflammatory mediator
1946 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
Potent ghrelin receptor inverse agonist; Antagonist at other neuropeptide receptors
1884 [D-Trp7,9,10]-Substance P
Inhibits M1 ACh receptor activation of Gq/11
1178 [Sar9,Met(O2)11]-Substance P
Potent and selective NK1 agonist
4935 Sulfasalazine
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
4943 Sulfidefluor 7 AM
H2S fluorescent probe
0731 Sulfisoxazole
Endothelin ETA antagonist
0162 S-Sulfo-L-cysteine sodium salt
Group I mGlu agonist
5146 Sulforhodamine 101
Red fluorescent dye; selective astrocyte marker
5442 Sulforhodamine 101 acid chloride
Red fluorescent dye; amine reactive
0894 (RS)-(±)-Sulpiride
Standard selective D2-like antagonist
0895 (S)-(-)-Sulpiride
Standard selective D2-like antagonist
3049 Sulprostone
EP3 and EP1 receptor agonist
2773 Sumanirole maleate
Selective D2 agonist
3586 Sumatriptan succinate
5-HT1A, 5-HT1B and 5-HT1D agonist
3768 Sunitinib malate
Potent VEGFR, PDGFRβ and KIT inhibitor
3543 Suplatast tosylate
Th2 cytokine synthesis inhibitor; antiasthmatic
6634 Surfen
Heparin sulfate antagonist
3208 Swainsonine
Inhibitor of α-mannosidase II
5118 SynaptoRedTM C2
Fluorescent dye; stains synaptic vesicles

Tocris Products by Catalog Number