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Displaying Products by Catalog Number (6700 - 6799)

Cat. No. Product Name / Activity
6700 PA Nic
Caged nicotine; photoactivated by one-photon and two-photon excitation
6701 1A-116
Rac1 inhibitor; blocks Rac1-P-Rex1 interaction
6703 BGP 15
PARP inhibitor; cytoprotectant
6704 Indo 1AM
Fluorescent Ca2+ indicator
6709 GSK 2018682
S1P1 and S1P5 agonist
6710 Darunavir
Highly potent HIV protease inhibitor
6712 A 77-01
Potent inhibitor of TGF-βRI
6715 A 71915
Highly potent and competitive NPRA antagonist
6716 Pomalidomide 4'-alkylC5-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6717 FFN 270
Fluorescent substrate for NET and VMAT2
6718 ±-MF 094
Selective USP30 inhibitor
6722 NBC 19
Potent NLRP3 inflammasome inhibitor
6724 CBA
Selective TRPM4 blocker
6725 CHDI 00390576
Potent and selective class IIa HDAC inhibitor; brain penetrant
6728 RGFP 966
Potent and selective HDAC3 inhibitor
6738 KT 182
Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
6739 YNT 185
Potent and selective OX2 agonist
6741 GW 4869
Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor
6742 Acetazolamide
Carbonic anhydrase inhibitor
6744 TL 13-12
Selective ALK Degrader (PROTAC®)
6745 TL 13-112
Selective ALK Degrader (PROTAC®)
6746 TL 13-110
Negative control for TL 13-112 (Cat. No. 6745)
6747 TL 13-22
Negative control for TL 13-12 (Cat. No. 6744)
6748 PRX 07034
Potent and selective 5-HT6 antagonist
6749 TH 5487
Selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor
6751 (R)-(-)-Ketamine hydrochloride
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine
6753 CHS 828
NAMPT inhibitor; active in vivo and cytotoxic
6754 LJI308
Potent pan-RSK inhibitor
6755 Darapladib
Potent lp-PLA2 inhibitor
6757 t-TUCB
Potent soluble epoxide hydrolase (sEH) Inhibitor; anti-inflammatory and antinociceptive
6758 CLP 290
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
6759 AA 147
ER proteostasis regulator
6760 Raphin 1
Inhibitor of the regulatory subunit PPP1R15B of protein phosphatase 1; orally bioavailable and brain penetrant
6762 Urolithin A
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
6764 B 973B
Positive allosteric modulator of α7 nAChRs; analgesic
6765 JTP 103237
Potent and selective monoacyglycerol acyltransferase 2 (MOGAT2) inhibitor
6766 AC 1903
Selective TRPC5 inhibitor
6770 ABT 639
CaV3.2 and CaV3.1 channel blocker; orally bioavailable
6771 PHPS1 sodium salt
Shp2 (PTPN11) inhibitor
6774 16673-34-0 NLRP3i
NLRP3 inflammasome inhibitor
6775 ST 045849
O-GlcNAc transferase (OGT) inhibitor
6776 G5
Ubiquitin isopeptidase inhibitor; induces apoptosis
6777 TAK 375
Very high affinity and selective melatonin receptor agonist
6779 Davunetide
Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo
6781 Capzimin dimer
Selective proteasome inhibitor
6782 Indisulam
Molecular glue; pre-mRNA splicing modulator
6784 FTBMT
Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
6785 E 7820
α2 integrin inhibitor; anti-angiogenic
6787 KI-7
Positive allosteric modulator of A2B receptors
6788 Quizartinib
Highly potent FLT3 inhibitor
6789 K 03861
Potent CDK2 inhibitor
6790 GSK 126
Very high affinity and selective EZH2 inhibitor
6791 BC-LI-0186
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
6792 Omipalisib
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
6793 Dasatinib
Highly potent pan-Src/Bcr-Abl inhibitor
6795 GeA-69
Selective allosteric PARP14 inhibitor
6798 Click N-Acetylmuramic acid - alkyne
Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes
6799 MB 0223
Dynamin-related GTPase DRP1 partial inhibitor

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