You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
ADAR1 (adenosine deaminases acting on double-stranded RNA) inhibitor. Reduces A-to-I editing activity in a leukemia cell line, restores let-7 and inhibits leukemia stem cells self-renewal in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 268.23. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.73 mL||18.64 mL||37.28 mL|
|5 mM||0.75 mL||3.73 mL||7.46 mL|
|10 mM||0.37 mL||1.86 mL||3.73 mL|
|50 mM||0.07 mL||0.37 mL||0.75 mL|
References are publications that support the biological activity of the product.
Zipeto et al (2016) ADAR1 activation drives leukemia stem cell self-renewal by impairing let-7 biogenesis. Cell Stem Cell 19 177 PMID: 27292188
Zhang and Slack et al (2016) ADARs edit microRNAs to promote leukemic stem cell activity. Cell Stem Cell 19 141 PMID: 27494666
If you know of a relevant reference for 8-Azaadenosine, please let us know.
View Related Products by Product Action
Keywords: 8-Azaadenosine, 8-Azaadenosine supplier, ADAR1, adenosine, deaminases, acting, on, double-stranded, RNA, dsRNA, leukemia, stem, cells, LSC, self-renewal, inhibitors, inhibits, Deaminases, Cancer, Stem, Cells, 6868, Tocris Bioscience
Citations for 8-Azaadenosine
Citations are publications that use Tocris products.
Currently there are no citations for 8-Azaadenosine. Do you know of a great paper that uses 8-Azaadenosine from Tocris? Please let us know.
Reviews for 8-Azaadenosine
There are currently no reviews for this product. Be the first to review 8-Azaadenosine and earn rewards!
Have you used 8-Azaadenosine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.