Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
ATPγS tetralithium salt is a P2 purinergic receptor agonist. Nonhydrolyzable analog of ATP (Cat. No. 3245).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 546.98. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||3.66 mL||18.28 mL||36.56 mL|
|2.5 mM||0.73 mL||3.66 mL||7.31 mL|
|5 mM||0.37 mL||1.83 mL||3.66 mL|
|25 mM||0.07 mL||0.37 mL||0.73 mL|
References are publications that support the biological activity of the product.
Evans et al (1995) Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors). Mol.Pharmacol. 48 178 PMID: 7544432
Peck and Herschlag (2003) Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor elF4A. RNA 9 1180 PMID: 13130132
Chrysogelos et al (1983) The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate). J.Biol.Chem. 258 12624 PMID: 6313668
If you know of a relevant reference for ATPγS tetralithium salt, please let us know.
Keywords: ATPgammaS tetralithium salt, ATPgammaS tetralithium salt supplier, ATPgammaS, ATPγ, ATPgS, ATP, analogs, purinergic, receptors, p2x, p2y, purinoceptors, agonists, ATP-gS, ATP-yS, P2X, Receptors, Purinergic, P2Y, 4080, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for ATPγS tetralithium salt include:
Miguel Cruz & Beall et al (2020) Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P2 Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance Front Physiol 11 PMID: 33101053
Aho et al (2016) Extracellular ATP protects endothelial cells against DNA damage. Purinergic Signal 12 575 PMID: 27030122
Gault et al (2014) Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol 207 767 PMID: 25533845
Handly & Wollman (2017) Wound-induced Ca2+ wave propagates through a simple release and diffusion mechanism. Mol Biol Cell 28 1457 PMID: 28404746
Do you know of a great paper that uses ATPγS tetralithium salt from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review ATPγS tetralithium salt and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.