New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7450 SGC CK2-1 Sep 2021
Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
TB1099-RMU Forskolin Sep 2021
Forskolin synthesised to Ancillary Material Grade
7057 VU 0071063 Sep 2021
Selective activator of SUR1 Kir6.2 channels
7304 JH-XI-10-02 Sep 2021
CDK8 Degrader (PROTAC®)
6141 BI-6901 Sep 2021
Potent and selective CCR10 antagonist
6804 Hoechst Janelia Fluor® 646 Sep 2021
Fluorogenic, red-emitting DNA probe
7460 SGC SMARCA-BRDVIII Sep 2021
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
7321 Pritelivir Sep 2021
Potent and selective herpes simplex virus (HSV) helicase primase inhibitor
6687 1R,3R-RSL3 Sep 2021
Negative control for 1S,3R-RSL3 (Cat. No. 6118)
6498 TASP 0277308 Sep 2021
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
7214 VH 032 amide-PEG2-acid Sep 2021
VHL ligand with PEG linker and terminal acid for onward chemistry
7406 Rf470DL Sep 2021
Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria
4894 ML 299 Sep 2021
Potent inhibitor of PLD1 and PLD2; CNS penetrant
5114 K34c Sep 2021
Potent and selective α5β1 integrin inhibitor
7421 LC 2 Epimer Sep 2021
Negative control for LC 2 (Cat. No. 7420)
7432 SIM1 Sep 2021
Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)
7157 YKL 5-124 Sep 2021
Potent and selective CDK7 inhibitor; induces cell cycle arrest
7408 OGDA Sep 2021
Green fluorescent D-amino acid; compatible with STED microscopy
7373 FNIR-Tag, NHS Sep 2021
Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester
7139 CeMMEC1 Sep 2021
TAF1 inhibitor
6862 Psoralen-triethylene glycol azide Sep 2021
RNA conformation probe; reagent for COMRADES RNA platform
7309 Vemurafenib Sep 2021
Potent BRAF and CRAF inhibitor
TB5758-RMU AGN 193109 Aug 2021
AGN 193109 synthesized to Ancillary Material Grade
TB6053-RMU LDN 193189 Aug 2021
LDN 193189 synthesized to Ancillary Material Grade
TB3000-RMU Gefitinib Aug 2021
Iressa synthesized to Ancillary Material Grade
TB0760-RMU AM 580 Aug 2021
AM 580 synthesized to Ancillary Material Grade
7486 Roxadustat Aug 2021
HIF-PH inhibitor; erythropoietic
7426 CG 428-Neg Aug 2021
Negative control for CG 428 (Cat. No. 7425)
7425 CG 428 Aug 2021
Potent tropomyosin receptor kinase (TRK) degrader
7371 Neratinib Aug 2021
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
6497 GSK 2833503A Aug 2021
Potent and selective TRPC6 and TRPC3 antagonist
7320 Methoxyluteolin Aug 2021
Inhibitor of pro-inflammatory mediator release from mast cells
7375 RO 8191 Aug 2021
IFNα receptor 2 agonist
7194 Erlotinib Hydrochloride Aug 2021
Potent, reversible EGFR tyrosine kinase inhibitor
7420 LC 2 Aug 2021
Selective KRAS PROTAC®
7419 Kyoto Probe-1 Aug 2021
Fluorescent probe that selectively identifies undifferentiated iPS/ES cells
3345 MLN 4760 Aug 2021
Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor
4327 JW 480 Jul 2021
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
7462 ET 18-OCH3 Jul 2021
Selective PI-PLC inhibitor, also PAF receptor agonist
7469 Pomalidomide 5'-piperazine-4-methylpiperidine Jul 2021
Cereblon ligand with terminal piperidine for onward chemistry
6977 Bobcat339 Jul 2021
Ten-eleven translocation methylcytosine dioxygenase (TET) inhibitor
7471 Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine Jul 2021
Cereblon ligand with terminal piperidine for onward chemistry
7470 Pomalidomide 5'-fluoro-6'-piperazine Jul 2021
Cereblon ligand with terminal piperazine for onward chemistry
7464 SJF 0661 Jul 2021
Negative control for SJF 0628 (Cat. No. 7463)
7463 SJF 0628 Jul 2021
Potent BRAF PROTAC®
7428 CG 858-Neg Jul 2021
Negative control for CG 858 (Cat. No. 7427)
7427 CG 858 Jul 2021
Selective BRAF-V600E protein Degrader (uSMITE™)
7468 Pomalidomide 5'-piperazine Jul 2021
Cereblon ligand with terminal piperazine for onward chemistry
7313 Hoechst Janelia Fluor® 526 Jul 2021
Fluorogenic, green-emitting DNA probe
7030 GW 280264X Jul 2021
Potent ADAM10 and ADAM17 inhibitor
7054 T4 Jul 2021
Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
7153 BRD 0539 Jul 2021
Cell permeable and reversible Cas9 inhibitor
6018 Nicotinamide Riboside Jul 2021
NAD+ precursor; substrate for nicotinamide riboside kinases
7324 Di 4 ANEPPS Jun 2021
Voltage-sensitive probe; used to detect changes in membrane potential in electrophysiology protocols
7336 Dinaciclib Jun 2021
Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
7391 O-Propargyl-puromycin Jun 2021
Puromycin analog for labeling newly synthesized proteins; is incorporated into nascent polypeptides
7439 Pomalidomide 4'-alkylC2-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7407 LEI 401 Jun 2021
High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
6941 Pyr 10 Jun 2021
Selective TRPC3 inhibitor
6848 GSK 2795039 Jun 2021
NADPH oxidase 2 (NOX2) inhibitor
7443 Pomalidomide 4'-alkylC6-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7442 Pomalidomide 4'-alkylC5-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7441 Pomalidomide 4'-alkylC4-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7452 FAM-DEALAHypYIPMDDDFQLRSF Jun 2021
Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity
7440 Pomalidomide 4'-alkylC3-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7438 Pomalidomide 4'-PEG6-azide Jun 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7401 tri-GalNAc COOH Jun 2021
Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
7437 Pomalidomide 4'-PEG5-azide Jun 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7414 DSRM-3716 Jun 2021
Potent and reversible SARM1 NAD hydrolase inhibitor
7403 Thalidomide 4'-ether-alkylC8-amine May 2021
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6871 MO-I-500 May 2021
FTO inhibitor; anticonvulsant
7129 RA 2 May 2021
Potent negative modulator of KCa2.3 and KCa3.1 channels
7295 SMCy 5.5 May 2021
Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
7314 Pepstatin A Janelia Fluor® 526 May 2021
Fluorogenic green-emitting lysosome tracker and stain
7315 Taxol Janelia Fluor® 526 May 2021
Green fluorescent taxol derivative; probe for microtubule staining
7240 ZNL 02-096 May 2021
Potent and selective Wee1 Degrader (PROTAC®)
7342 Emetine dihydrochloride May 2021
RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
7306 FC 11 May 2021
Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®)
7275 Laurdan May 2021
Polarity sensitive lipid membrane fluorescent probe; used to imaging lipid rafts
5985 AKT Inhibitor IV May 2021
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
7436 Pomalidomide 4'-PEG4-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7435 Pomalidomide 4'-PEG3-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7434 Pomalidomide 4'-PEG1-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7307 Pomalidomide 4'-PEG2-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7404 VH 032 amide-alkylC9-acid May 2021
VHL ligand with alkyl linker and terminal acid for onward chemistry
7135 AKOS 022 May 2021
Voltage-dependent anion channel (VDAC) inhibitor
7055 WS 383 May 2021
Potent, selective and reversible DCN1-UBC12 interaction inhibitor
7387 Nile Red May 2021
Fluorogenic lipid membrane dye
6738 KT 182 May 2021
Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
7229 Galidesivir dihydrochloride Apr 2021
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
7218 PZM21 Apr 2021
Selective μ receptor agonist
7134 ARN 14494 Apr 2021
Potent serine palmitoyltransferase inhibitor
7271 Brivaracetam Apr 2021
SV2A ligand; antiepileptic
7390 Tissue Clearing Pro-Organoid Apr 2021
3D cell culture clearing reagent kit
7389 Tissue Clearing Pro Apr 2021
Tissue clearing reagent kit
6975 Teniposide Apr 2021
DNA topoisomerase II inhibitor; viral transduction enhancer
7402 TAT-Gap19(I130A) Apr 2021
Control peptide for TAT-Gap19
7289 Nimbolide Apr 2021
RNF114 inhibitor
7316 Janelia Fluor 526®, SE Apr 2021
Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
6973 NS 3728 Apr 2021
VRAC blocker
4687 ML 252 Apr 2021
Potent and selective KV7.2 inhibitor; brain penetrant
7396 MS 154N Mar 2021
Negative control for MS 154 (Cat No. 7395)
7398 MS 39N Mar 2021
Negative control for MS 39 (Cat. No. 7397)
7395 MS 154 Mar 2021
Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR