New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7316 | Janelia Fluor 526®, SE | Apr 2021 |
| Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm | ||
| 6975 | Teniposide | Apr 2021 |
| DNA topoisomerase II inhibitor; viral transduction enhancer | ||
| 7402 | TAT-Gap19(I130A) | Apr 2021 |
| Control peptide for TAT-Gap19 | ||
| 7289 | Nimbolide | Apr 2021 |
| RNF114 inhibitor | ||
| 6973 | NS 3728 | Apr 2021 |
| VRAC blocker | ||
| 4687 | ML 252 | Apr 2021 |
| Potent and selective KV7.2 inhibitor; brain penetrant | ||
| 7396 | MS 154N | Mar 2021 |
| Negative control for MS 154 (Cat No. 7395) | ||
| 7398 | MS 39N | Mar 2021 |
| Negative control for MS 39 (Cat. No. 7397) | ||
| 7395 | MS 154 | Mar 2021 |
| Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR | ||
| TB3742-RMU | RepSox | Mar 2021 |
| RepSox synthesized to Ancillary Material Grade | ||
| TB4855-RMU | WIKI4 | Mar 2021 |
| WIKI4 synthesized to Ancillary Material Grade | ||
| TB2634-RMU | DAPT | Mar 2021 |
| DAPT synthesized to Ancillary Material Grade | ||
| 7003 | NAI-N3 | Mar 2021 |
| Reagent for RNA icSHAPE experiments in vivo | ||
| 7328 | Photo-lenalidomide-acid | Mar 2021 |
| Functionalized photoswitchable cereblon ligand for Degraders | ||
| 7325 | Human LAMP primers (18S rRNA) | Mar 2021 |
| LAMP primer set for use as positive control in RT-LAMP assays for SARS-CoV-2 detection | ||
| 7327 | SARS-CoV-2 LAMP primers (ORF1a) | Mar 2021 |
| LAMP primer set for SARS CoV-2, which targets ORF1a | ||
| 7326 | SARS-CoV-2 LAMP primers (N gene) | Mar 2021 |
| LAMP primer set for SARS CoV-2, which targets N gene | ||
| 7397 | MS 39 | Mar 2021 |
| Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR | ||
| 7118 | cis-22a | Mar 2021 |
| TRPV6 inhibitor | ||
| 7372 | CDK8/19i | Mar 2021 |
| Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture | ||
| 7340 | Tocriscreen Stem Cell Library | Mar 2021 |
| A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling | ||
| 7120 | SNIPER(ER)-87 | Mar 2021 |
| Potent and selective ERα Degrader (SNIPER) | ||
| 6499 | MLN 4924 | Mar 2021 |
| Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable | ||
| 7388 | ND1-YL2 | Feb 2021 |
| SRC-1 peptide-based PROTAC®; active in vivo | ||
| 7319 | BRD PHOTAC-I-3 | Feb 2021 |
| Photoswitchable BET bromodomain Degrader (PHOTAC) | ||
| 7033 | AY 77 | Feb 2021 |
| Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling | ||
| 7217 | VH 032 amide-alkylC5-acid | Feb 2021 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7195 | MCU i4 | Feb 2021 |
| Negative modulator of mitochondrial Ca2+ uniporter (MCU) | ||
| 6741 | GW 4869 | Feb 2021 |
| Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor | ||
| 7034 | AY 254 | Feb 2021 |
| Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling | ||
| 7265 | GMB 475 | Feb 2021 |
| BCR-ABL1 kinase PROTAC® | ||
| 7366 | WM 3835 | Feb 2021 |
| Lysine acetyltransferase HBO1 (KAT7) inhibitor | ||
| 7256 | ARV 771 | Feb 2021 |
| Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells | ||
| 6693 | WM 8014 | Feb 2021 |
| Potent and selective KAT6A and KAT6B inhibitor | ||
| 7273 | C-Laurdan | Jan 2021 |
| Two-photon polarity-sensitive lipid membrane probe | ||
| 7175 | DOPE | Jan 2021 |
| Liposome/lipoplex transfection enhancer | ||
| 7374 | dTAGV-1 hydrochloride | Jan 2021 |
| Hydrochloride salt of dTAGV-1 (Cat. No. 6914); suitable for in vivo use | ||
| 7282 | Bortezomib | Jan 2021 |
| High affinity proteasome inhibitor | ||
| 7268 | SJFα | Jan 2021 |
| Potent and selective p38α PROTAC® | ||
| 7192 | SMIP 004 | Jan 2021 |
| SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase | ||
| 7352 | YM 254890 | Jan 2021 |
| Gα-protein inhibitor; potent inhibitor of Gq/11 signaling | ||
| 6261 | VCP 171 | Jan 2021 |
| Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist | ||
| 7216 | VH 032 amide-alkylC3-acid | Dec 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7267 | SJFδ | Dec 2020 |
| Potent and selective p38δ PROTAC® | ||
| 7377 | BIIE 0246 hydrochloride | Dec 2020 |
| Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo | ||
| 7266 | SJF 8240 | Dec 2020 |
| c-MET PROTAC®; also degrades exon-14-deleted c-MET | ||
| 7228 | MPro 13b | Dec 2020 |
| Coronavirus Mpro inhibitor | ||
| 7312 | HM Janelia Fluor® 526, SE | Dec 2020 |
| Fluorogenic spontaneously blinking green-emitting dye; for SMLSM; λabsλem 526/550 nm | ||
| 7184 | SGC 6870N | Dec 2020 |
| Negative control for SGC 6870 (Cat. No. 7182) | ||
| 7182 | SGC 6870 | Dec 2020 |
| Potent and selective PRMT6 inhibitor | ||
| 7370 | 3-Aminotyrosine | Dec 2020 |
| Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors | ||
| 7353 | MSA 2 | Dec 2020 |
| Non-nucleotide STING agonist; orally bioavailable | ||
| 7322 | SP 10 | Dec 2020 |
| Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction | ||
| 6990 | SET 2 | Dec 2020 |
| Selective TRPV2 antagonist | ||
| 7338 | K 22 | Dec 2020 |
| Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation | ||
| 7156 | WQ 1 | Dec 2020 |
| Potent and selective σ1 receptor antagonist; active in vivo | ||
| 7073 | VH 032 amide-alkylC3-amine | Dec 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7131 | TM 38837 | Dec 2020 |
| Highly potent CB1 inverse agonist; peripherally restricted | ||
| 6562 | BAY 707 | Dec 2020 |
| Potent and selective MTH1 inhibitor | ||
| 7105 | VH 032 amide-PEG5-acid | Nov 2020 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7258 | Gefitinib-based PROTAC® 3 | Nov 2020 |
| Potent EGFR PROTAC® | ||
| 7255 | ARCC 4 negative control | Nov 2020 |
| Negative control for ARCC 4 (Cat. No. 7254) | ||
| 7197 | JHU 37152 | Nov 2020 |
| High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant | ||
| 7303 | iHAP1 | Nov 2020 |
| Allosteric activator of protein phosphatase 2A (PP2A) | ||
| 7254 | ARCC 4 | Nov 2020 |
| Potent and selective androgen receptor PROTAC® | ||
| 7213 | Pomalidomide 4'-PEG4-acid | Nov 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 7260 | TBK1 control PROTAC® 4 | Nov 2020 |
| Negative control for TBK1 PROTAC® 3i (Cat. No. 7259) | ||
| 7302 | Sulfo-NHS-LC-Biotin | Nov 2020 |
| Amine reactive biotinylation reagent, cell impermeable | ||
| 5927 | NS 383 | Nov 2020 |
| ASIC blocker; active in vivo | ||
| 6322 | LW 6 | Nov 2020 |
| Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α | ||
| 7259 | TBK1 PROTAC® 3i | Nov 2020 |
| Potent TANK-binding kinase 1 (TBK1) PROTAC® | ||
| 7198 | JHU 37160 | Nov 2020 |
| High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant | ||
| 7357 | PLpro inhibitor 6 | Oct 2020 |
| SARS-CoV and SARS-CoV-2 PLpro inhibitor | ||
| 7199 | (±)-Eriodictyol | Oct 2020 |
| Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling | ||
| 7294 | VH 101 phenol-alkylC6-amine | Oct 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7059 | GLPG 0187 | Oct 2020 |
| Potent αv integrin inhibitor | ||
| 7193 | Deschloroclozapine | Oct 2020 |
| High affinity and highly potent activator of hM3Dq and hM4Di DREADDs; rapidly blood brain barrier penetrant | ||
| 7329 | Thalidomide 4'-ether-alkylC2-acid | Oct 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7106 | VH 032 amide-alkylC2-acid | Oct 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7350 | Tocriscreen Antiviral Library | Oct 2020 |
| Antiviral compound library for high throughput screening, chemical biology applications and drug repurposing; contains 240 bioactive compounds (100 μL 10 mM DMSO solutions) | ||
| 7219 | CRBN PROTAC® 14a | Oct 2020 |
| Cereblon Degrader (PROTAC®) | ||
| 7188 | Carfilzomib | Oct 2020 |
| Potent irreversible proteasome inhibitor; active in vivo |