Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.
| Cat No | Product Name / Activity | Date Added |
|---|---|---|
| 5914 | AM 0902 | Oct 2017 |
| Potent and selective TRPA1 antagonist | ||
| 6102 | Ep23, 5'-DY647 | Oct 2017 |
| High affinity fluorescently tagged aptamer for EpCam | ||
| 6310 | AZD 1208 | Oct 2017 |
| Potent pan Pim kinase inhibitor | ||
| 6163 | AR 420626 | Oct 2017 |
| FFA3 agonist | ||
| 6103 | CD133-A15, 5'-DY647 | Oct 2017 |
| High affinity fluorescently tagged aptamer for CD133 (AC133 epitope) | ||
| 6104 | CD133-B19, 5'-DY647 | Oct 2017 |
| High affinity fluorescently tagged aptamer for CD133 (extracellular domain epitope) | ||
| 6329 | Clozapine N-oxide dihydrochloride | Sep 2017 |
| Activator of muscarinic DREADDs | ||
| 5831 | SAR 7334 | Sep 2017 |
| Potent TRPC6 inhibitor | ||
| 6099 | Lalistat 2 | Sep 2017 |
| Selective lysosomal acid lipase inhibitor | ||
| 6370 | Nor NOHA monoacetate | Sep 2017 |
| Arginase inhibitor | ||
| 6308 | PEN (mouse) | Sep 2017 |
| GPR83 agonist | ||
| 6347 | PF 04628935 | Sep 2017 |
| Potent ghrelin receptor inverse agonist | ||
| 6346 | PF 5006739 | Sep 2017 |
| Potent CK1δ/ε inhibitor | ||
| 6309 | PEN (rat) | Sep 2017 |
| GPR83 agonist | ||
| 6307 | PEN (human) | Sep 2017 |
| GPR83 agonist | ||
| 5924 | ER 819762 | Sep 2017 |
| Potent EP4 receptor antagonist; orally bioavailable | ||
| 6084 | ASP 9521 | Sep 2017 |
| Potent 17β-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable | ||
| 6051 | G 5555 | Sep 2017 |
| High affinity group 1 PAK inhibitor | ||
| 6075 | Nutlin 3a | Sep 2017 |
| MDM2 antagonist; active enantiomer of Nutlin-3 (Cat. No. 3984) | ||
| 5863 | PF 04620110 | Sep 2017 |
| Potent and selective DGAT-1 inhibitor; orally bioavailable | ||
| 6345 | PF 04991532 | Sep 2017 |
| Potent hepatoselective glucokinase activator | ||
| 6342 | Tamoxifen | Sep 2017 |
| Estrogen receptor partial agonist/antagonist | ||
| 6336 | Trazodone hydrochloride | Sep 2017 |
| 5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant | ||
| 6192 | PZ-II-029 | Sep 2017 |
| α6β3γ2-selective GABAA channel modulator | ||
| 6142 | CL 075 | Sep 2017 |
| TLR8 agonist | ||
| 5523 | TAPI 0 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 6013 | TAPI 2 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 6162 | TAPI 1 | Sep 2017 |
| ADAM-17 (TACE) and MMP inhibitor | ||
| 6237 | FPS ZM1 | Aug 2017 |
| High affinity antagonist of RAGE | ||
| 6143 | WZB 117 | Aug 2017 |
| GLUT inhibitor | ||
| 5956 | NF 1819 | Aug 2017 |
| Potent and selective irreversible MAGL inhibitor; membrane permeable and brain penetrant | ||
| 5401 | GSK 2250665A | Aug 2017 |
| Itk inhibitor | ||
| 6083 | PSB 12379 | Aug 2017 |
| Ecto-5'-nucleotidase (CD73) inhibitor | ||
| 6327 | dBET1 | Aug 2017 |
| (+)-JQ1 based PROTAC that selectively degrades BRD4 in cells | ||
| 6240 | DG 041 | Aug 2017 |
| Potent and selective EP3 antagonist; antiplatelet and antithrombotic | ||
| 6049 | PF 04937319 | Aug 2017 |
| Glucokinase partial activator | ||
| 6048 | R-BC154 | Aug 2017 |
| High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs | ||
| 6196 | Brequinar sodium | Aug 2017 |
| Potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor | ||
| 6119 | OB 24 hydrochloride | Aug 2017 |
| Potent and selective heme oxygenase 1 (HO-1) inhibitor | ||
| 6230 | Rucaparib camsylate | Aug 2017 |
| PARP inhibitor | ||
| 6098 | Lalistat 1 | Aug 2017 |
| Potent and selective lysosomal acid lipase (LAL) inhibitor | ||
| 6289 | JH-II-127 | Aug 2017 |
| Potent and selective LRRK2 inhibitor | ||
| 5818 | NVP BSK 805 | Aug 2017 |
| Potent JAK2 inhibitor; orally bioavailable | ||
| 5705 | M62812 | Aug 2017 |
| TLR-4 inhibitor | ||
| 6038 | SR 10067 | Aug 2017 |
| Selective Rev-Erbα/β agonist; anxiolytic | ||
| 6193 | AM 4113 | Aug 2017 |
| Selective, high affinity CB1 antagonist | ||
| 6278 | JNJ 55511118 | Aug 2017 |
| Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8 | ||
| 6299 | MS 15203 | Aug 2017 |
| Potent and selective GPR171 partial agonist | ||
| 6116 | BHPI | Aug 2017 |
| ERα antagonist; also activates unfolded protein response; active in vivo | ||
| 6231 | Dacomitinib | Jul 2017 |
| Potent irreversible pan ErbB inhibitor | ||
| 6167 | A 196 | Jul 2017 |
| Potent and selective SUV420H1/H2 inhibitor | ||
| 6265 | Lonafarnib | Jul 2017 |
| Potent farnesyl transferase inhibitor | ||
| 5768 | HS 38 | Jul 2017 |
| ATP-competitive inhibitor of DAPK and ZIPK | ||
| 6016 | IN 1130 | Jul 2017 |
| Potent and selective inhibitor of TGF-βRI | ||
| 6078 | BPTU | Jul 2017 |
| P2Y1 allosteric antagonist | ||
| 6045 | NITD 008 | Jul 2017 |
| Antiviral; selective flavivirus inhibitor | ||
| 6291 | ELA-32 (human) | Jul 2017 |
| Potent, high affinity apelin receptor agonist; stimulates angiogenesis | ||
| 6306 | BigLEN (rat) | Jul 2017 |
| Potent GPR171 agonist | ||
| 6304 | BigLEN (mouse) | Jul 2017 |
| GPR171 agonist | ||
| 6292 | ELARR>GG | Jul 2017 |
| Negative control for ELA-32 (Cat.No.6291). | ||
| 6317 | Prasugrel | Jul 2017 |
| Irreversible P2Y12 antagonist; antiplatelet and orally active | ||
| 6287 | st-Ht31 P | Jul 2017 |
| Negative control for st-Ht31 (Cat. No. 6286) | ||
| 6191 | TH 1020 | Jul 2017 |
| Toll-like receptor (TLR) 5/Flagellin complex antagonist | ||
| 6286 | st-Ht31 | Jul 2017 |
| Inhibits PKA/AKAP interactions; cell permeable | ||
| 6165 | AC 265347 | Jul 2017 |
| CaSR biased allosteric modulator | ||
| 5658 | AR-C 141990 hydrochloride | Jul 2017 |
| MCT1 inhibitor | ||
| 6301 | Parathyroid hormone (1-34) (rat) | Jun 2017 |
| Parathyroid hormone (PTH) receptor agonist | ||
| 6284 | BRD 73954 | Jun 2017 |
| Dual histone deacetylase (HDAC) 6/8 inhibitor | ||
| 6288 | Peptide YY (3-36) human | Jun 2017 |
| NPY Y2 receptor agonist | ||
| 6270 | Tubastatin A hydrochloride | Jun 2017 |
| Potent HDAC6 inhibitor | ||
| 6128 | GSK 343 | Jun 2017 |
| Potent and selective SAM-competitive EZH2 inhibitor | ||
| 6303 | Parathyroid hormone (1-34) (bovine) | Jun 2017 |
| Parathyroid hormone (PTH) receptor agonist. | ||
| 6073 | P21d hydrochloride | Jun 2017 |
| Potent and selective Brk inhibitor | ||
| 6208 | MS 275 | Jun 2017 |
| HDAC (Class I) inhibitor | ||
| 6189 | Myricetin | Jun 2017 |
| Irreversible TrxR inhibitor | ||
| 6293 | ELA-14 (human) | Jun 2017 |
| Potent apelin (APJ) receptor agonist | ||
| 6302 | Pomalidomide | Jun 2017 |
| Cereblon ubiquitination inhibitor; also TNF-α inhibitor and antiangiogenic | ||
| 6294 | ELA-14 negative control | Jun 2017 |
| Negative control for ELA-14 (Cat.No.6293). | ||
| 6282 | BRD 4770 | Jun 2017 |
| G9a inhibitor and S-adenosyl methionine mimetic; cell permeable | ||
| 4930 | UNC 2399 | Jun 2017 |
| Biotinylated UNC 1999 (Cat.No. 4904) | ||
| 5103 | Lys-CoA | Jun 2017 |
| Selective p300 inhibitor | ||
| 6185 | Pemetrexed | Jun 2017 |
| High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART | ||
| 6174 | CVT 313 | Jun 2017 |
| cdk2 inhibitor | ||
| 6277 | 7α,25-Dihydroxycholesterol | Jun 2017 |
| Highly potent GPR183 (EBI2) agonist | ||
| 6194 | TM 5441 | Jun 2017 |
| Plasminogen activator inhibitor-1 (PAI-1) inhibitor | ||
| 6305 | Lenalidomide | Jun 2017 |
| Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase | ||
| 4322 | JH 295 | May 2017 |
| Irreversible Nek2 inhibitor | ||
| 5343 | TPPB | May 2017 |
| High affinity PKC activator; also APP modulator | ||
| 6311 | Tadalafil | May 2017 |
| Potent and highly selective PDE5 inhibitor; orally bioavailable | ||
| 6271 | ST 034307 | May 2017 |
| Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo | ||
| 6258 | CC 401 dihydrochloride | May 2017 |
| High affinity JNK inhibitor; also inhibits HCMV replication | ||
| 6181 | OTX 015 | May 2017 |
| BET bromodomain inhibitor; orally bioavailable | ||
| 6012 | OXSI 2 | May 2017 |
| Potent Syk kinase inhibitor; also inhibits assembly of NLRP3 inflammasomes | ||
| 5675 | AZ PFKFB3 26 | May 2017 |
| Potent and selective PFKFB3 inhibitor | ||
| 5821 | C-DIM 12 | May 2017 |
| Nurr1 activator; inhibits NF-κB-dependent gene expression | ||
| 6060 | AZD 2461 | May 2017 |
| Potent PARP inhibitor; orally bioavailable | ||
| 5921 | D9 | May 2017 |
| Potent thioredoxin reductase (TrxR) inhibitor | ||
| 6121 | NB-caged Tyrosine hydrochloride | May 2017 |
| ortho-nitrobenzyl caged L- tyrosine | ||
| 5150 | NCL 00017509 | May 2017 |
| Potent and reversible NIMA related kinase 2 (Nek2) inhibitor | ||
| 6036 | STK16-IN-1 | May 2017 |
| Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases. | ||
| 6285 | Megestrol Acetate | May 2017 |
| Synthetic progesterone analog | ||
| 5826 | LEI 101 hydrochloride | May 2017 |
| Potent and selective CB2 partial agonist; orally biovailable | ||
| 5842 | MK 386 | May 2017 |
| Potent, selective human type 1 5α-reductase inhibitor | ||
| 5888 | MOPSO, free acid | May 2017 |
| Buffer; working pH range in aqueous solution: 6.2-7.6 | ||
| 6061 | XMD 8-87 | May 2017 |
| Potent Ack1/TNK2 inhibitor | ||
| 5372 | Bioymifi | May 2017 |
| DR5 (TRAIL receptor) agonist; induces apoptosis | ||
| 5963 | CMPI hydrochloride | May 2017 |
| Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs | ||
| 6215 | H3K4(Me2) (1-20) | May 2017 |
| Histone H3 peptide | ||
| 5452 | SKI 178 | May 2017 |
| Non-lipid sphingosine kinase 1 (SphK1) inhibitor | ||
| 3974 | Latrunculin B | May 2017 |
| Inhibitor of actin polymerization | ||
| 6259 | RAGE antagonist peptide | May 2017 |
| RAGE antagonist | ||
| 6183 | Nanchangmycin | May 2017 |
| Antiviral; active against Zika, West Nile and dengue viruses | ||
| 6100 | Fasentin | May 2017 |
| GLUT1/GLUT4 inhibitor; also Fas-sensitizer | ||
| 6158 | (S)-Equol | May 2017 |
| Potent estrogen receptor β (ERβ) agonist; dihydrotestosterone antagonist | ||
| 6164 | SEA 0400 | Apr 2017 |
| Potent Na+/Ca2+ exchanger (NCX) inhibitor. | ||
| 6152 | LDN 214117 | Apr 2017 |
| Potent and selective ALK2 inhibitor |