New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7216 | VH 032 amide-alkylC3-acid | Dec 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7267 | SJFδ | Dec 2020 |
| Potent and selective p38δ degrader | ||
| 7377 | BIIE 0246 hydrochloride | Dec 2020 |
| Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo | ||
| 7266 | SJF 8240 | Dec 2020 |
| c-MET Degrader; also degrades exon-14-deleted c-MET | ||
| 7228 | MPro 13b | Dec 2020 |
| Coronavirus Mpro inhibitor | ||
| 7184 | SGC 6870N | Dec 2020 |
| Negative control for SGC 6870 (Cat. No. 7182) | ||
| 7182 | SGC 6870 | Dec 2020 |
| Potent and selective PRMT6 inhibitor | ||
| 7370 | 3-Aminotyrosine | Dec 2020 |
| Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors | ||
| 7353 | MSA 2 | Dec 2020 |
| Non-nucleotide STING agonist; orally bioavailable | ||
| 7312 | HM Janelia Fluor® 526, SE | Dec 2020 |
| Spontaneously blinking green-emitting dye for SMLSM; λabsλem 526/550 nm | ||
| 7322 | SP 10 | Dec 2020 |
| Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction | ||
| 6990 | SET 2 | Dec 2020 |
| Selective TRPV2 antagonist | ||
| 7131 | TM 38837 | Dec 2020 |
| Highly potent CB1 inverse agonist; peripherally restricted | ||
| 7338 | K 22 | Dec 2020 |
| Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation | ||
| 7156 | WQ 1 | Dec 2020 |
| Potent and selective σ1 receptor antagonist; active in vivo | ||
| 7073 | VH 032 amide-alkylC3-amine | Dec 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6562 | BAY 707 | Dec 2020 |
| Potent and selective MTH1 inhibitor | ||
| 7105 | VH 032 amide-PEG5-acid | Nov 2020 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7258 | Gefitinib-based PROTAC® 3 | Nov 2020 |
| Potent EGFR Degrader | ||
| 7303 | iHAP1 | Nov 2020 |
| Allosteric activator of protein phosphatase 2A (PP2A) | ||
| 7255 | ARCC 4 negative control | Nov 2020 |
| Negative control for ARCC 4 (Cat. No. 7254) | ||
| 7197 | JHU 37152 | Nov 2020 |
| High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant | ||
| 7254 | ARCC 4 | Nov 2020 |
| Potent and selective androgen receptor degrader | ||
| 7213 | Pomalidomide 4'-PEG4-acid | Nov 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 7260 | TBK1 control PROTAC® 4 | Nov 2020 |
| Negative control for TBK1 PROTAC® 3i (Cat. No. 7259) | ||
| 7302 | Sulfo-NHS-LC-Biotin | Nov 2020 |
| Amine reactive biotinylation reagent, cell impermeable | ||
| 7259 | TBK1 PROTAC® 3i | Nov 2020 |
| Potent TANK-binding kinase 1 (TBK1) Degrader | ||
| 7198 | JHU 37160 | Nov 2020 |
| High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant | ||
| 5927 | NS 383 | Nov 2020 |
| ASIC blocker; active in vivo | ||
| 6322 | LW 6 | Nov 2020 |
| Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α | ||
| 7357 | PLpro inhibitor 6 | Oct 2020 |
| SARS-CoV and SARS-CoV-2 PLpro inhibitor | ||
| 7199 | (±)-Eriodictyol | Oct 2020 |
| Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling | ||
| 7294 | VH 101 phenol-alkylC6-amine | Oct 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7059 | GLPG 0187 | Oct 2020 |
| Potent αv integrin inhibitor | ||
| 7193 | Deschloroclozapine | Oct 2020 |
| High affinity and highly potent activator of hM3Dq and hM4Di DREADDs; rapidly blood brain barrier penetrant | ||
| 7329 | Thalidomide 4'-ether-alkylC2-acid | Oct 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7219 | CRBN PROTAC® 14a | Oct 2020 |
| Cereblon Degrader | ||
| 7188 | Carfilzomib | Oct 2020 |
| Potent irreversible proteasome inhibitor; active in vivo | ||
| 7106 | VH 032 amide-alkylC2-acid | Oct 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7350 | Tocriscreen Antiviral Library | Oct 2020 |
| Antiviral compound library for high throughput screening, chemical biology applications and drug repurposing; contains 240 bioactive compounds (100 μL 10 mM DMSO solutions) | ||
| 7331 | Thalidomide 4'-ether-alkylC4-acid | Oct 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7285 | DCLK1-IN-1 | Oct 2020 |
| Potent and selective doublecortin like kinase 1/2 (DCLK1/2) inhibitor; orally bioavailable | ||
| 7293 | VH 101 phenol-alkylC4-amine | Oct 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7143 | VX 765 | Oct 2020 |
| High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable | ||
| 7335 | Thalidomide 4'-ether-alkylC8-acid | Oct 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 5950 | Ethyl LipotF | Oct 2020 |
| Selective FTO inhibitor | ||
| 7287 | FAM-DEALA-Hyp-YIPD | Sep 2020 |
| Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity | ||
| 7330 | Thalidomide 4'-ether-alkylC3-acid | Sep 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 6996 | BOP-JF549 | Sep 2020 |
| Yellow fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 549; fluorogenic; photostable | ||
| 7191 | Santacruzamate A | Sep 2020 |
| Highly potent and selective HDAC2 inhibitor | ||
| 7334 | Thalidomide 4'-ether-alkylC7-acid | Sep 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7333 | Thalidomide 4'-ether-alkylC6-acid | Sep 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7332 | Thalidomide 4'-ether-alkylC5-acid | Sep 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7104 | VH 032 amide-PEG1-acid | Sep 2020 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7279 | Janelia Fluor® 646, Tetrazine | Sep 2020 |
| Red dye (Reactive group: tetrazine). Applications: super-resolution microscopy e.g. dSTORM & STED, confocal and live cell imaging | ||
| 7277 | HBC 530 | Sep 2020 |
| GFP fluorophore mimic for imaging RNA in live cells; activated by binding to Pepper aptamers; suitable for confocal and two-photon microscopy | ||
| 7298 | xStAx-VHLL | Sep 2020 |
| Selective peptide-based β-catenin degrader | ||
| 7095 | Pomalidomide 4'-PEG5-acid | Sep 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 6238 | PKRA 7 | Sep 2020 |
| Potent prokineticin (PK) 1 and 2 receptor antagonist; antitumor; BBB penetrant | ||
| 7178 | LCL 161, phenol | Sep 2020 |
| Functionalized IAP ligand for PROTACs | ||
| 7262 | SJF 1528 | Sep 2020 |
| Potent EGFR Degrader; also degrades HER2 | ||
| 7159 | FMF-04-159-R | Sep 2020 |
| Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14 | ||
| 7158 | FMF-04-159-2 | Sep 2020 |
| Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members | ||
| 6913 | Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine | Sep 2020 |
| Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry | ||
| 7288 | Thalidomide-Cyanine 5 | Sep 2020 |
| Fluorescent cereblon probe | ||
| 7076 | Lenalidomide 4'-PEG3-amine | Sep 2020 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7075 | Lenalidomide 4'-PEG1-amine | Sep 2020 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7261 | SJF 1521 | Sep 2020 |
| Selective EGFR Degrader | ||
| 7170 | D-GsMTx4 | Aug 2020 |
| TRPC1/6 and Piezo2 inhibitor; resistant to proteolytic digestion | ||
| 7283 | Apilimod dimesylate | Aug 2020 |
| Potent and selective PIKfyve inhibitor | ||
| 7187 | Zanamivir | Aug 2020 |
| Potent influenza virus neuraminidase inhibitor | ||
| 7091 | Miro1 Reducer | Aug 2020 |
| Promotes mitochondrial Rho GTPase 1 (Miro1) degradation | ||
| 7093 | Lenalidomide 4'-PEG2-amine | Aug 2020 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7231 | EIDD 1931 | Aug 2020 |
| Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide | ||
| 6267 | Taxol Janelia Fluor ® 549 | Aug 2020 |
| Yellow fluorescent taxol derivative; probe for microtubule staining | ||
| 6916 | dTAG-13-NEG | Aug 2020 |
| Negative control for dTAG-13 (Cat. No. 6605) | ||
| 6915 | dTAGV-1-NEG | Aug 2020 |
| Negative control for dTAGV-1 (Cat. No. 6914) | ||
| 6914 | dTAGV-1 | Aug 2020 |
| Potent and selective degrader of mutant FKBP12F36V fusion proteins | ||
| 7209 | Pomalidomide 4'-alkylC4-acid | Aug 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7029 | GX 201 | Aug 2020 |
| Potent and selective Nav1.7 blocker; analgesic | ||
| 6997 | BOP-JF646 | Aug 2020 |
| Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable | ||
| 7280 | GRL 0617 | Aug 2020 |
| Coronavirus PLpro inhibitor | ||
| 7290 | Famotidine | Aug 2020 |
| Potent and high affinity H2 biased inverse agonist | ||
| 6297 | AP 20187 | Aug 2020 |
| Chemical inducer of protein dimerization; active in vivo | ||
| 7189 | Saracatinib | Aug 2020 |
| Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable | ||
| 7212 | Pomalidomide 4'-PEG2-acid | Jul 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 7270 | iP300w | Jul 2020 |
| Potent p300/CBP inhibitor | ||
| 6789 | K 03861 | Jul 2020 |
| Potent Cdk2 inhibitor | ||
| 7272 | dNTP solution mix | Jul 2020 |
| Mixture of deoxynucleotides for use in PCR | ||
| 7211 | Pomalidomide 4'-alkylC8-acid | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7108 | VH 032 amide-alkylC8-acid | Jul 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7107 | VH 032 amide-alkylC6-acid | Jul 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7094 | Pomalidomide 4'-PEG1-acid | Jul 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry |