New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7578 | Tocriscreen Epigenetics 3.0 | Jan 2022 |
| A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening and chemical biology applications | ||
| 7457 | CAM 833 | Jan 2022 |
| Selective orthosteric inhibitor of the BRCA2-RAD51 interaction | ||
| 7579 | Olaparib | Jan 2022 |
| Potent PARP inhibitor | ||
| 7206 | 5-Ethynyluridine | Jan 2022 |
| Uridine analog, used for labeling RNA synthesis | ||
| 7497 | Vandetanib | Jan 2022 |
| Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity | ||
| 7541 | Helianorphin-19 | Jan 2022 |
| Opioid receptor (KOR) agonist | ||
| 7549 | BAY 1816032 | Jan 2022 |
| Potent and selective BUB1 kinase inhibitor | ||
| 7466 | BI dihydrochloride | Jan 2022 |
| DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers | ||
| 6955 | Ceapin A7 | Jan 2022 |
| Selective inhibitor of ATF6α; sensitizes cells to ER stress | ||
| 7551 | NCT 02 | Dec 2021 |
| Molecular glue; induces degradation of CCNK and CDK12 | ||
| 7504 | MD15 | Dec 2021 |
| Negative control for MD13 (Cat. No. 7503) | ||
| 7575 | aTAG 2139-NEG | Dec 2021 |
| Negative control for aTAG 2139 (Cat. no. 6970) | ||
| 7566 | VH 032 amide-alkylC9-amine | Dec 2021 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7477 | Lyophilized qPCR Master Mix | Dec 2021 |
| Lyophilized qPCR Master Mix | ||
| 7568 | VH 032 amide-PEG6-amine | Dec 2021 |
| VHL ligand with PEG linker and terminal amine for onward chemistry | ||
| 7478 | Lyophilized OneStep RT-qPCR Master Mix | Dec 2021 |
| Lyophilized OneStep RT-qPCR Master Mix | ||
| 7405 | TWS 119 | Dec 2021 |
| Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation | ||
| 4340 | TAK 779 | Nov 2021 |
| Potent and selective CCR5 and CCR2 chemokine receptor antagonist | ||
| 7527 | TSA Vivid Fluorophore Kit 650 | Nov 2021 |
| Signal amplification kit for use in ISH, ICC and IHC | ||
| 7526 | TSA Vivid Fluorophore Kit 570 | Nov 2021 |
| Signal amplification kit for use in ISH, ICC and IHC | ||
| 7523 | TSA Vivid Fluorophore Kit 520 | Nov 2021 |
| Signal amplification kit for use in ISH, ICC and IHC | ||
| 7503 | MD13 | Nov 2021 |
| Potent MIF Degrader (PROTAC®) | ||
| TB4703-RMU | DZNep HCl | Nov 2021 |
| 3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade | ||
| 6965 | CGI 1746 | Nov 2021 |
| Potent, reversible BTK inhibitor | ||
| 7474 | EN6 | Nov 2021 |
| H+ ATPase activator; activates autophagy; inactivates mTORC1 signaling | ||
| 6718 | ±-MF 094 | Nov 2021 |
| Selective USP30 inhibitor | ||
| TB4489-RMU | DBZ | Nov 2021 |
| DBZ synthesized to Ancillary Material Grade | ||
| 7515 | Lenalidomide 4'-PEG3-azide | Nov 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7509 | NR12S | Nov 2021 |
| Fluorogenic lipid membrane dye | ||
| 7310 | Emricasan | Nov 2021 |
| Potent pan-caspase inhibitor | ||
| 6979 | SEN 177 | Nov 2021 |
| Potent glutaminyl cyclase inhibitor; disrupts binding of SIRP-α to CD47 | ||
| 7433 | cis-SIM1 | Nov 2021 |
| Negative control for SIM1 (Cat. No. 7432) | ||
| 3786 | Celecoxib | Oct 2021 |
| Selective cyclooxygenase-2 (COX-2) inhibitor | ||
| 3784 | Sildenafil citrate | Oct 2021 |
| Potent PDE5 inhibitor; orally active | ||
| 7508 | EMD 527040 hydrochloride | Oct 2021 |
| ανβ6 integrin inhibitor | ||
| 7454 | Cediranib | Oct 2021 |
| Potent inhibitor of VEGFR, PDGFR and FGFR | ||
| 7337 | Cysmethynil | Oct 2021 |
| ICMT inhibitor; arrests cell-cycle at G1 phase | ||
| 7516 | Lenalidomide 4'-alkylC3-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7410 | PARPYnD | Oct 2021 |
| PARP inhibitor; photoaffinity probe | ||
| 7379 | CB 5083 | Oct 2021 |
| Potent p97 ATPase inhibitor | ||
| 7521 | Thalidomide 4'-ether-alkylC3-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7520 | Thalidomide 4'-ether-PEG3-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7424 | EMI 48 | Oct 2021 |
| Inhibitor of EGFR mutants | ||
| 7513 | Lenalidomide 4'-PEG1-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7522 | Thalidomide 4'-ether-alkylC5-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7519 | Thalidomide 4'-ether-PEG2-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7518 | Thalidomide 4'-ether-PEG1-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7473 | Lenalidomide 5'-piperazine-4-methylpiperidine | Oct 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 7472 | Lenalidomide 5'-piperazine | Oct 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7445 | GPR52 Comp-43 | Oct 2021 |
| GPR52 receptor antagonist | ||
| 7517 | Lenalidomide 4'-alkylC5-azide | Oct 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7514 | Lenalidomide 4'-PEG2-azide | Oct 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7341 | STX 64 | Oct 2021 |
| Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II | ||
| 7431 | Cyanine 5.5, SE | Oct 2021 |
| Far red fluorescent dye for the labeling of amines; supplied as NHS ester | ||
| 7305 | Defactinib | Sep 2021 |
| Potent and selective FAK and Pyk2 inhibitor | ||
| 7458 | iBET-BD2 | Sep 2021 |
| Potent and selective pan-BD2 inhibitor; orally bioavailable | ||
| 7242 | Ac-FLTD-CMK | Sep 2021 |
| Potent and selective inhibitor of caspases 1, 5 and 4 | ||
| 7086 | StemRegenin 1 | Sep 2021 |
| Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment | ||
| 7489 | TCH-165 | Sep 2021 |
| Enhancer of 20S proteasome assembly and 20S-mediated protein degradation | ||
| 6141 | BI-6901 | Sep 2021 |
| Potent and selective CCR10 antagonist | ||
| 7460 | SGC SMARCA-BRDVIII | Sep 2021 |
| Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor | ||
| 7450 | SGC CK2-1 | Sep 2021 |
| Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2 | ||
| 7321 | Pritelivir | Sep 2021 |
| Potent and selective herpes simplex virus (HSV) helicase primase inhibitor | ||
| 6498 | TASP 0277308 | Sep 2021 |
| Potent and selective S1P1 receptor antagonist; inhibits angiogenesis | ||
| 6687 | 1R,3R-RSL3 | Sep 2021 |
| Negative control for 1S,3R-RSL3 (Cat. No. 6118) | ||
| 7304 | JH-XI-10-02 | Sep 2021 |
| CDK8 Degrader (PROTAC®) | ||
| 6804 | Hoechst Janelia Fluor® 646 | Sep 2021 |
| Fluorogenic, red-emitting DNA probe | ||
| 7057 | VU 0071063 | Sep 2021 |
| Selective activator of SUR1 Kir6.2 channels | ||
| TB1099-RMU | Forskolin | Sep 2021 |
| Forskolin synthesized to Ancillary Material Grade | ||
| 5114 | K34c | Sep 2021 |
| Potent and selective α5β1 integrin inhibitor | ||
| 4894 | ML 299 | Sep 2021 |
| Potent inhibitor of PLD1 and PLD2; CNS penetrant | ||
| 7406 | Rf470DL | Sep 2021 |
| Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 7214 | VH 032 amide-PEG2-acid | Sep 2021 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7421 | LC 2 Epimer | Sep 2021 |
| Negative control for LC 2 (Cat. No. 7420) | ||
| 7432 | SIM1 | Sep 2021 |
| Potent and selective trivalent BET Bromodomain Degrader (PROTAC®) | ||
| 7157 | YKL 5-124 | Sep 2021 |
| Potent and selective CDK7 inhibitor; induces cell cycle arrest | ||
| 7373 | FNIR-Tag, NHS | Sep 2021 |
| Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester | ||
| 6862 | Psoralen-triethylene glycol azide | Sep 2021 |
| RNA conformation probe; reagent for COMRADES RNA platform | ||
| 7309 | Vemurafenib | Sep 2021 |
| Potent BRAF and CRAF inhibitor | ||
| 7139 | CeMMEC1 | Sep 2021 |
| TAF1 inhibitor | ||
| 7408 | OGDA | Sep 2021 |
| Green fluorescent D-amino acid; compatible with STED microscopy | ||
| TB0760-RMU | AM 580 | Aug 2021 |
| AM 580 synthesized to Ancillary Material Grade | ||
| TB5758-RMU | AGN 193109 | Aug 2021 |
| AGN 193109 synthesized to Ancillary Material Grade | ||
| TB6053-RMU | LDN 193189 | Aug 2021 |
| LDN 193189 synthesized to Ancillary Material Grade | ||
| TB3000-RMU | Gefitinib | Aug 2021 |
| Iressa synthesized to Ancillary Material Grade | ||
| 7486 | Roxadustat | Aug 2021 |
| HIF-PH inhibitor; erythropoietic | ||
| 7425 | CG 428 | Aug 2021 |
| Potent tropomyosin receptor kinase (TRK) degrader | ||
| 7371 | Neratinib | Aug 2021 |
| Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor | ||
| 6497 | GSK 2833503A | Aug 2021 |
| Potent and selective TRPC6 and TRPC3 antagonist | ||
| 7426 | CG 428-Neg | Aug 2021 |
| Negative control for CG 428 (Cat. No. 7425) | ||
| 7320 | Methoxyluteolin | Aug 2021 |
| Inhibitor of pro-inflammatory mediator release from mast cells | ||
| 7375 | RO 8191 | Aug 2021 |
| IFNα receptor 2 agonist | ||
| 7194 | Erlotinib Hydrochloride | Aug 2021 |
| Potent, reversible EGFR tyrosine kinase inhibitor | ||
| 7419 | Kyoto Probe-1 | Aug 2021 |
| Fluorescent probe that selectively identifies undifferentiated iPS/ES cells | ||
| 7420 | LC 2 | Aug 2021 |
| Selective KRAS PROTAC® | ||
| 3345 | MLN 4760 | Aug 2021 |
| Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor | ||
| 4327 | JW 480 | Jul 2021 |
| Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1) | ||
| 7462 | ET 18-OCH3 | Jul 2021 |
| Selective PI-PLC inhibitor, also PAF receptor agonist | ||
| 6977 | Bobcat339 | Jul 2021 |
| Ten-eleven translocation methylcytosine dioxygenase (TET) inhibitor | ||
| 7469 | Pomalidomide 5'-piperazine-4-methylpiperidine | Jul 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry |