New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7991 CEPT Cocktail Kit Sep 2023
Cell culture supplement for improving stem cell survival
TB4055-RMU L-Ascorbic acid Sep 2023
L-Ascorbic acid synthesized to Ancillary Material Grade
7924 Pomalidomide 4'-PEG5-amine Sep 2023
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7799 CCT 369260 Sep 2023
Molecular glue; induces degradation of BCL6
7734 proTAME Sep 2023
Cell-permeable APC/C inhibitor
7897 Sakura 6 Sep 2023
Promoter of SERT and nNOS interaction
7729 Phenyl-glutarimide 4'-piperazine Sep 2023
Piperazine-functionalized cereblon ligand for PROTAC development
TB3532-RMU endo-IWR 1 Sep 2023
endo-IWR 1 synthesized to Ancillary Material Grade
7800 CPS2 Sep 2023
Potent and selective CDK2 degrader (PROTAC®)
7953 CELT-211 Sep 2023
Fluorescent serotonin 5HT2B receptor ligand for HTS
7928 KRpep-2d Sep 2023
Potent and selective KRASG12D inhibitor
7894 Auxinole Aug 2023
Auxin antagonist of TIR1/AFB receptors; also OsTIR1 inhibitor in auxin-inducible degron (AID) system
7868 PE 22-28 Aug 2023
Potent inhibitor of TREK-1 channels
7907 DC 432 Aug 2023
Potent peptidomimetic inhibitor of N-terminal methyltransferase 1/2
7856 MQAE Aug 2023
Fluorescent Cl- indicator; membrane permeable
7952 CELT-133 Aug 2023
Selective hα1A adrenergic receptor fluorescent antagonist
7866 IDR 1002 Aug 2023
Innate defence regulator peptide
7774 VH 032 Aug 2023
Inhibitor of VHL; blocks interaction of VHL and HIF-α
7955 CELT-426 Aug 2023
Potent and partially selective hD2 dopamine receptor fluorescent antagonist
7954 CELT-327 Aug 2023
Potent and selective hA2B/A3 adenosine receptor fluorescent antagonist
8007 C 101248 Jul 2023
Selective and potent inhibitor of both mouse and human THIK-1
TB4106-RMU Nicotinamide Jul 2023
Nicotinamide synthesized to Ancillary Material Grade
7917 TM2 TEAD inhibitor Jul 2023
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
7816 UNC 6852 Jul 2023
Polycomb repressive complex 2 (PRC2) Degrader PROTAC®
8015 tri-GalNAc-PEG3-Azide Jul 2023
Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry
7945 Cholesterol Jul 2023
Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity
7925 VH 032 amide-alkylC7-acid Jul 2023
VHL ligand with alkyl linker and terminal acid for onward chemistry
7921 DBCO-NHS Jul 2023
Amine reactive and azide reactive building block
7923 Pomalidomide 4'-alkylC6-amine Jul 2023
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7909 ARN 11391 Jul 2023
Potentiator of the IP3-gated calcium channel ITPR1
7944 DMG-PEG 2000 Jul 2023
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
7943 DSPC Jul 2023
Neutral phospholipid; component of lipid nanoparticles (LNPs)
7745 CST 905 Jul 2023
Potent and selective BRAFV600E Degrader (PROTAC®)
7722 JQ1-FITC Jul 2023
Fluorescent BET bromodomain probe; suitable for use in TR-FRET
7810 eIF4A i28 Jul 2023
eIF4A inhibitor
7648 AS 99 Jul 2023
Selective ASH1L histone methyltransferase inhibitor
7444 DA ZP1 Jul 2023
Fluorogenic Zn(II) sensor for isolation of stem cell derived β cells
7633 BDY FL Thalidomide Jul 2023
High affinity fluorescent probe for TR-FRET cereblon binding assay
7864 LY 2109761 Jul 2023
Selective TGF-β kinase inhibitor
7916 Risdiplam Jul 2023
Selective SMN2 gene splicing modifier
7882 HDAC4 CHDI Degrader 11 Jul 2023
Potent and selective HDAC4 Degrader (PROTAC®)
7845 AZ1 USP25/28 inhibitor Jul 2023
Selective USP25 and USP28 inhibitor
8009 Z-DEVD-FMK Caspase-3 Inhibitor Jun 2023
Caspase-3 Inhibitor
7975 AzP3S Jun 2023
Reagent for modifying RNA via 2'-OH sulfonylation; for SHAPE MaP experiments
7920 CoraFluor™ 1, amine reactive Jun 2023
Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation
7904 RU.521 Jun 2023
Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)
7870 ING-2 AM Jun 2023
Fluorescent sodium ion (Na+) indicator, membrane permeable
7879 CHDI 00484077 Jun 2023
Potent and selective HDAC class IIa inhibitor
7871 IPG-4 AM Jun 2023
Fluorescent potassium ion (K+) indicator, membrane permeable
7946 DLin-MC3-DMA Jun 2023
Component of lipid nanoparticles (LNPs); ionizable cationic lipid
7673 BAY 091 Jun 2023
Potent and selective PIP4K2A inhibitor
7855 Mag-Fura-2 AM Jun 2023
Magnesium (Mg2+) indicator, membrane permeable
7317 T 5224 Jun 2023
Selective inhibitor of c-Fos/activator protein (AP)-1
7873 Phen Green SK diacetate Jun 2023
Heavy metal ion indicator, membrane permeable
7820 CU-76 Jun 2023
Selective inhibitor of cyclic GMP-AMP synthase (cGAS)
7422 TH 1760 Jun 2023
Potent and selective NUDT15 hydrolase inhibitor
7878 XIE62-1004 Jun 2023
Inducer of autophagy via interaction of p62 and LC3
7481 BCI May 2023
DUSP6 and DUSP1 inhibitor
7926 MOMBA May 2023
Selective orthostatic agonist of hFFA2-DREADDs
7511 ARN 3236 May 2023
Potent inhibitor of salt-inducible kinases
7818 GSK 215 May 2023
Potent and selective focal adhesion kinase (FAK) degrader
7813 LL-K9-3 May 2023
Selective HyT-based degrader of the CDK9-cyclin T1 complex
7863 THPTA May 2023
Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
7721 SJ 11646 May 2023
Potent and selective LCK Degrader (PROTAC®)
7576 (+)-JQ1 maleimide May 2023
JQ1-maleimide functionalized probe; induces proteasomal degradation of BRD4
7524 Biotin-PEG3-Azide May 2023
Biotin with PEG linker and reactive click handle
7974 P3S May 2023
Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments
7962 TAT-SAMβA Peptide May 2023
Selective antagonist of Mfn1-βIIPKC association
7699 AUTAC4 Apr 2023
Mitochondrial targeting AUTAC Degrader
7791 WS 6 Apr 2023
Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons
7809 TEPP 46 Apr 2023
Potent and selective pyruvate kinase M2 (PKM2) allosteric activator
7833 preQ1-azide Apr 2023
preQ1 with azide handle for click chemistry
7892 dTAG-Fluorescein Apr 2023
Fluorescent probe for labeling mutant FKBP12F36V proteins
7898 ZZL 7 Mar 2023
Inhibitor of SERT and nNOS interaction
7176 DC-Cholesterol hydrochloride Mar 2023
Cationic cholesterol derivative
7645 FHT 2344 Mar 2023
Potent SMARCA2/4 inhibitor
7902 PIK 90 Mar 2023
Potent PI3K inhibitor, also used in hPSCs mesendoderm differentiation
7842 NAMPT PROTAC® A7 Mar 2023
Potent and selective nicotinamide phosphoribosyl transferase (NAMPT) Degrader (PROTAC®)