New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7189 | Saracatinib | Aug 2020 |
| Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable | ||
| 7270 | iP300w | Jul 2020 |
| Potent p300/CBP inhibitor | ||
| 7212 | Pomalidomide 4'-PEG2-acid | Jul 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 6789 | K 03861 | Jul 2020 |
| Potent Cdk2 inhibitor | ||
| 7272 | dNTP solution mix | Jul 2020 |
| Mixture of deoxynucleotides for use in PCR | ||
| 7211 | Pomalidomide 4'-alkylC8-acid | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7108 | VH 032 amide-alkylC8-acid | Jul 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7107 | VH 032 amide-alkylC6-acid | Jul 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7094 | Pomalidomide 4'-PEG1-acid | Jul 2020 |
| Cereblon ligand with PEG linker and terminal acid for onward chemistry | ||
| 7230 | MPro N3 | Jul 2020 |
| Coronavirus Mpro inhibitor | ||
| 7097 | Pomalidomide 4'-alkylC7-acid | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7160 | DD 03-171 | Jul 2020 |
| Potent and selective BTK Degrader | ||
| 7087 | AGI 5198 | Jul 2020 |
| Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1) | ||
| 6316 | ASB 14780 | Jul 2020 |
| Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable | ||
| 7235 | Arbidol | Jul 2020 |
| Broad spectrum antiviral | ||
| 7210 | Pomalidomide 4'-alkylC6-acid | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7208 | Pomalidomide 4'-alkylC7-amine | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7204 | Pomalidomide 4'-PEG3-amine | Jul 2020 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7203 | Pomalidomide 4'-PEG1-amine | Jul 2020 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7096 | Pomalidomide 4'-alkylC3-acid | Jul 2020 |
| Cereblon ligand with alkyl linker and terminal acid for onward chemistry | ||
| 6873 | DC 271 | Jul 2020 |
| Fluorescent retinoic acid analog; solvochromatic probe | ||
| 7224 | Oseltamivir phosphate | Jul 2020 |
| Influenza virus neuraminidase inhibitor; antiviral prodrug | ||
| 6943 | dBRD9-A | Jul 2020 |
| Potent BRD9 Degrader | ||
| 7234 | Nitazoxanide | Jul 2020 |
| Pyruvate flavodoxin/ferredoxin oxidoreductase inhibitor; also inhibits Wnt signaling; broad spectrum anti-infective | ||
| 6130 | AP 1903 | Jul 2020 |
| Chemical inducer of protein dimerization; active in vivo | ||
| 6945 | dBET6 | Jun 2020 |
| Potent and selective (+)-JQ1 based PROTAC targeting BET bromodomains, active in vivo | ||
| 7220 | A 410099.1 amide-PEG4-amine | Jun 2020 |
| IAP ligand with PEG linker and terminal amine for onward chemistry | ||
| 7221 | A 410099.1 amide-PEG5-amine | Jun 2020 |
| IAP ligand with PEG linker and terminal amine for onward chemistry | ||
| 7001 | AT 7867 | Jun 2020 |
| Potent pan-Akt and PKA inhibitor | ||
| 7081 | LY 2886721 Hydrochloride | Jun 2020 |
| Potent and selective β-secretase (BACE) inhibitor | ||
| 7227 | GS 441524 | Jun 2020 |
| Viral RNA-dependent RNA polymerase inhibitor; broad spectrum antiviral nucelotide | ||
| 7226 | Remdesivir | Jun 2020 |
| Viral RNA-dependent RNA polymerase inhibitor; broad spectrum antiviral nucelotide prodrug | ||
| 7246 | Nucleic Acid Dye Green I | Jun 2020 |
| High affinity double-stranded DNA (dsDNA) probe; used in RT-LAMP and qPCR | ||
| 7232 | SBP1-FITC | Jun 2020 |
| Fluorescent ACE2-derived peptide; binds receptor binding domain of SARS-CoV-2 spike protein | ||
| 7052 | Lopinavir | Jun 2020 |
| Highly potent and selective HIV-1 protease inhibitor | ||
| 7056 | Conduritol B epoxide | Jun 2020 |
| Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models | ||
| 6391 | CD38 inhibitor 78c | Jun 2020 |
| Potent CD38 inhibitor; active in vivo | ||
| 6430 | Takinib | Jun 2020 |
| Potent and selective TAK1/MAP3K7 kinase inhibitor | ||
| 7205 | Pomalidomide 4'-alkylC3-amine | Jun 2020 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7222 | Baricitinib | Jun 2020 |
| Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2 | ||
| 7223 | Dabrafenib mesylate | Jun 2020 |
| Potent and selective B-Raf, CDK16 and NEK9 inhibitor; anticancer; also targets human proteins in the SARS-CoV-2 interactome | ||
| 7225 | Favipiravir | Jun 2020 |
| Viral RNA polymerase inhibitor | ||
| 6599 | Yhhu 3792 | Jun 2020 |
| Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo | ||
| 7177 | NR 7h | May 2020 |
| Potent and selective p38α and p38β degrader; active in vivo | ||
| 6807 | NNC 0640 | May 2020 |
| Negative allosteric modulator of glucagon and GLP-1 receptors | ||
| 7233 | SBP1 | May 2020 |
| ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain | ||
| 6896 | Dynapyrazole A | May 2020 |
| Hedgehog signaling inhibitor; dynein inhibitor | ||
| 6962 | JBJ-03-142-02 | May 2020 |
| Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors | ||
| 6831 | TRPV3 74a | May 2020 |
| Selective TRPV3 antagonist; brain penetrant | ||
| 6650 | YADA | May 2020 |
| Green-yellow lucifer yellow-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 6825 | SGC 3027 | May 2020 |
| Potent and selective PRMT7 inhibitor | ||
| 6838 | SGC 3027N | May 2020 |
| Negative control for SGC 3027 (Cat. No. 6825) | ||
| 6354 | CNV Dopamine | May 2020 |
| Caged dopamine; photolysed by UV light | ||
| 7004 | NAI | May 2020 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable | ||
| 6998 | SHIN 1 | May 2020 |
| Potent SHMT inhibitor | ||
| 7082 | DL 175 | Apr 2020 |
| Potent and selective GPR84 agonist | ||
| 5755 | PF 04479745 | Apr 2020 |
| Potent and selective 5-HT2C agonist | ||
| 6944 | Pomalidomide 4'-alkylC8-amine | Apr 2020 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7116 | Chemerin-9, Human | Apr 2020 |
| Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin | ||
| 7117 | Chemerin-9, Mouse | Apr 2020 |
| Potent CMKLR1 agonist; c-terminal peptide of full length mouse chemerin | ||
| 6779 | Davunetide | Apr 2020 |
| Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo | ||
| 6892 | RIPGBM | Apr 2020 |
| RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant | ||
| 5814 | GoSlo SR 5-69 | Apr 2020 |
| BK channel activator | ||
| 7200 | Tocriscreen FDA-Approved Drugs Library | Apr 2020 |
| Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA | ||
| 6722 | NBC 19 | Apr 2020 |
| Potent NLRP3 inflammasome inhibitor | ||
| 6649 | RADA | Apr 2020 |
| Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 7090 | Digoxigenin-11-dUTP | Mar 2020 |
| Hapten modified dUTP for ISH | ||
| 6826 | AZ 1729 | Mar 2020 |
| FFA2 allosteric agonist; displays bias for the Gi signaling pathway | ||
| 6939 | cis-VZ 185 | Mar 2020 |
| Negative control for VZ 185 (Cat. No. 6936) | ||
| 6739 | YNT 185 | Mar 2020 |
| Potent and selective OX2 agonist | ||
| 7163 | Chroman 1 | Mar 2020 |
| Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis | ||
| 7074 | VH 032 amide-alkylC7-amine | Mar 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6911 | VH 032, phenol | Mar 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 6758 | CLP 290 | Mar 2020 |
| K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242) | ||
| 6670 | TP 238 | Mar 2020 |
| CECR2 and BPTF/FALZ inhibitor | ||
| 6372 | PSB CB5 | Mar 2020 |
| Selective GPR18 antagonist | ||
| 6976 | JNJ 10198409 | Mar 2020 |
| Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases | ||
| 7048 | Ruxolitinib phosphate | Feb 2020 |
| Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor | ||
| 7162 | iFSP1 | Feb 2020 |
| Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer | ||
| 7064 | Ruxolitinib | Feb 2020 |
| Potent and selective JAK1/JAK2 inhibitor; orally bioavailable | ||
| 7121 | 7-Aminoactinomycin D | Feb 2020 |
| Fluorescent DNA stain | ||
| 6928 | VU 6001966 | Feb 2020 |
| Potent and selective negative allosteric modulator of mGlu2 receptors | ||
| 6833 | RO 5263397 hydrochloride | Feb 2020 |
| Potent TA1 receptor agonist | ||
| 7088 | Janelia Fluor® 646, Azide | Feb 2020 |
| Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging | ||
| 7038 | Palonosetron hydrochloride | Feb 2020 |
| Highly potent and high affinity 5-HT3 antagonist | ||
| 7039 | SK 609 | Feb 2020 |
| Dopamine D3 receptor biased agonist | ||
| 6791 | BC-LI-0186 | Feb 2020 |
| Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor | ||
| 6110 | HJC 0416 hydrochloride | Feb 2020 |
| STAT3 inhibitor |