New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 6848 | GSK 2795039 | Jun 2021 |
| NADPH oxidase 2 (NOX2) inhibitor | ||
| 7443 | Pomalidomide 4'-alkylC6-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7442 | Pomalidomide 4'-alkylC5-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7441 | Pomalidomide 4'-alkylC4-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7414 | DSRM-3716 | Jun 2021 |
| Potent and reversible SARM1 NAD hydrolase inhibitor | ||
| 7401 | tri-GalNAc COOH | Jun 2021 |
| Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry | ||
| 7452 | FAM-DEALAHypYIPMDDDFQLRSF | Jun 2021 |
| Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity | ||
| 7440 | Pomalidomide 4'-alkylC3-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7438 | Pomalidomide 4'-PEG6-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7437 | Pomalidomide 4'-PEG5-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7403 | Thalidomide 4'-ether-alkylC8-amine | May 2021 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6871 | MO-I-500 | May 2021 |
| FTO inhibitor; anticonvuslant | ||
| 7129 | RA 2 | May 2021 |
| Potent negative modulator of KCa2.3 and KCa3.1 channels | ||
| 7295 | SMCy 5.5 | May 2021 |
| Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy | ||
| 7306 | FC 11 | May 2021 |
| Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®) | ||
| 7342 | Emetine dihydrochloride | May 2021 |
| RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika | ||
| 7314 | Pepstatin A Janelia Fluor® 526 | May 2021 |
| Fluorogenic green-emitting lysosome probe | ||
| 7315 | Taxol Janelia Fluor® 526 | May 2021 |
| Green fluorescent taxol derivative; probe for microtubule staining | ||
| 7240 | ZNL 02-096 | May 2021 |
| Potent and selective Wee1 Degrader (PROTAC®) | ||
| 7275 | Laurdan | May 2021 |
| Polarity sensitive lipid membrane fluorescent probe | ||
| 5985 | AKT Inhibitor IV | May 2021 |
| Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates | ||
| 7436 | Pomalidomide 4'-PEG4-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7404 | VH 032 amide-alkylC9-acid | May 2021 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7307 | Pomalidomide 4'-PEG2-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7435 | Pomalidomide 4'-PEG3-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7434 | Pomalidomide 4'-PEG1-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7135 | AKOS 022 | May 2021 |
| Voltage-dependent anion channel (VDAC) inhibitor | ||
| 7055 | WS 383 | May 2021 |
| Potent, selective and reversible DCN1-UBC12 interaction inhibitor | ||
| 7387 | Nile Red | May 2021 |
| Fluorogenic lipid membrane dye | ||
| 6738 | KT 182 | May 2021 |
| Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor | ||
| 7218 | PZM21 | Apr 2021 |
| Selective μ receptor agonist | ||
| 7229 | Galidesivir dihydrochloride | Apr 2021 |
| Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral | ||
| 7134 | ARN 14494 | Apr 2021 |
| Potent serine palmitoyltransferase inhibitor | ||
| 7271 | Brivaracetam | Apr 2021 |
| SV2A ligand; antiepileptic | ||
| 7390 | Tissue Clearing Pro-Organoid | Apr 2021 |
| 3D cell culture clearing reagent kit | ||
| 7389 | Tissue Clearing Pro | Apr 2021 |
| Tissue clearing reagent kit | ||
| 7402 | TAT-Gap19(I130A) | Apr 2021 |
| Control peptide for TAT-Gap19 | ||
| 7289 | Nimbolide | Apr 2021 |
| RNF114 inhibitor | ||
| 7316 | Janelia Fluor 526®, SE | Apr 2021 |
| Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm | ||
| 6975 | Teniposide | Apr 2021 |
| DNA topoisomerase II inhibitor; viral transduction enhancer | ||
| 6973 | NS 3728 | Apr 2021 |
| VRAC blocker | ||
| 4687 | ML 252 | Apr 2021 |
| Potent and selective KV7.2 inhibitor; brain penetrant | ||
| 7396 | MS 154N | Mar 2021 |
| Negative control for MS 154 (Cat No. 7395) | ||
| 7398 | MS 39N | Mar 2021 |
| Negative control for MS 39 (Cat. No. 7397) | ||
| 7395 | MS 154 | Mar 2021 |
| Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR | ||
| TB3742-RMU | RepSox | Mar 2021 |
| RepSox synthesized to Ancillary Material Grade | ||
| TB4855-RMU | WIKI4 | Mar 2021 |
| WIKI4 synthesized to Ancillary Material Grade | ||
| TB2634-RMU | DAPT | Mar 2021 |
| DAPT synthesized to Ancillary Material Grade | ||
| 7328 | Photo-lenalidomide-acid | Mar 2021 |
| Functionalized photoswitchable cereblon ligand for Degraders | ||
| 7003 | NAI-N3 | Mar 2021 |
| Reagent for RNA icSHAPE experiments in vivo | ||
| 7372 | CDK8/19i | Mar 2021 |
| Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture | ||
| 7340 | Tocriscreen Stem Cell Library | Mar 2021 |
| A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling | ||
| 7397 | MS 39 | Mar 2021 |
| Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR | ||
| 7118 | cis-22a | Mar 2021 |
| TRPV6 inhibitor | ||
| 7120 | SNIPER(ER)-87 | Mar 2021 |
| Potent and selective ERα Degrader (SNIPER) | ||
| 6499 | MLN 4924 | Mar 2021 |
| Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable | ||
| 7388 | ND1-YL2 | Feb 2021 |
| SRC-1 peptide-based PROTAC®; active in vivo | ||
| 7319 | BRD PHOTAC-I-3 | Feb 2021 |
| Photoswitchable BET bromodomain Degrader (PHOTAC) | ||
| 7033 | AY 77 | Feb 2021 |
| Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling | ||
| 7195 | MCU i4 | Feb 2021 |
| Negative modulator of mitochondrial Ca2+ uniporter (MCU) | ||
| 7217 | VH 032 amide-alkylC5-acid | Feb 2021 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 6741 | GW 4869 | Feb 2021 |
| Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor | ||
| 7366 | WM 3835 | Feb 2021 |
| Lysine acetyltransferase HBO1 (KAT7) inhibitor | ||
| 7034 | AY 254 | Feb 2021 |
| Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling | ||
| 7265 | GMB 475 | Feb 2021 |
| BCR-ABL1 kinase PROTAC® | ||
| 7256 | ARV 771 | Feb 2021 |
| Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells | ||
| 6693 | WM 8014 | Feb 2021 |
| Potent and selective KAT6A and KAT6B inhibitor | ||
| 7374 | dTAGV-1 hydrochloride | Jan 2021 |
| Hydrochloride salt of dTAGV-1 (Cat. No. 6914); suitable for in vivo use | ||
| 7273 | C-Laurdan | Jan 2021 |
| Two-photon polarity-sensitive lipid membrane probe | ||
| 7175 | DOPE | Jan 2021 |
| Liposome/lipoplex transfection enhancer | ||
| 7282 | Bortezomib | Jan 2021 |
| High affinity proteasome inhibitor | ||
| 7268 | SJFα | Jan 2021 |
| Potent and selective p38α PROTAC® | ||
| 7192 | SMIP 004 | Jan 2021 |
| SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase | ||
| 7352 | YM 254890 | Jan 2021 |
| Gα-protein inhibitor; potent inhibitor of Gq/11 signaling | ||
| 6261 | VCP 171 | Jan 2021 |
| Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist | ||
| 7377 | BIIE 0246 hydrochloride | Dec 2020 |
| Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo | ||
| 7216 | VH 032 amide-alkylC3-acid | Dec 2020 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7267 | SJFδ | Dec 2020 |
| Potent and selective p38δ PROTAC® | ||
| 7266 | SJF 8240 | Dec 2020 |
| c-MET PROTAC®; also degrades exon-14-deleted c-MET |