New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7064 | Ruxolitinib | Feb 2020 |
| Potent and selective JAK1/JAK2 inhibitor; orally bioavailable | ||
| 7121 | 7-Aminoactinomycin D | Feb 2020 |
| Fluorescent DNA stain | ||
| 7162 | iFSP1 | Feb 2020 |
| Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer | ||
| 7038 | Palonosetron hydrochloride | Feb 2020 |
| Highly potent and high affinity 5-HT3 antagonist | ||
| 6928 | VU 6001966 | Feb 2020 |
| Potent and selective mGlu2 negative allosteric modulator | ||
| 7088 | Janelia Fluor® 646, Azide | Feb 2020 |
| Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging | ||
| 6833 | RO 5263397 hydrochloride | Feb 2020 |
| Potent TA1 receptor agonist | ||
| 7039 | SK 609 | Feb 2020 |
| Dopamine D3 receptor biased agonist | ||
| 6791 | BC-LI-0186 | Feb 2020 |
| Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor | ||
| 6110 | HJC 0416 hydrochloride | Feb 2020 |
| STAT3 inhibitor | ||
| 6993 | Janelia Fluor® 646, free acid | Feb 2020 |
| Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging | ||
| 5746 | NESS 0327 | Feb 2020 |
| Ultra-high affinity and selective CB1 antagonist | ||
| 7040 | C 176 | Feb 2020 |
| mSTING antagonist | ||
| 7150 | Tocriscreen 2.0 Max | Jan 2020 |
| A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions) | ||
| 6457 | Cyanine 3 Tyramide | Jan 2020 |
| Orange fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6220 | PM 226 | Jan 2020 |
| Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective | ||
| 6456 | Fluorescein Tyramide | Jan 2020 |
| Green fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 7015 | IA-Alkyne | Jan 2020 |
| Broad spectrum cysteine reactive probe | ||
| 6458 | Cyanine 5 Tyramide | Jan 2020 |
| Red fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6398 | SKA 121 | Jan 2020 |
| Positive allosteric modulator of KCa3.1 channels | ||
| TB3748-GMP | XAV 939 | Jan 2020 |
| XAV 939 synthesized to cGMP guidelines | ||
| 6858 | MMG 11 | Jan 2020 |
| TLR2 antagonist | ||
| 6925 | NBC 6 | Jan 2020 |
| NLRP3 inflammasome inhibitor | ||
| 7152 | Tocriscreen 2.0 Micro | Jan 2020 |
| A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions) | ||
| 7151 | Tocriscreen 2.0 Mini | Jan 2020 |
| A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions) | ||
| 6985 | VH 032 amide-alkylC5-amine | Jan 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7051 | Tasquinimod | Jan 2020 |
| High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic | ||
| 6964 | LY 2119620 | Jan 2020 |
| Positive allosteric modulator of M2 and M4 receptors | ||
| 6952 | VH 101, phenol | Jan 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 6725 | CHDI 00390576 | Dec 2019 |
| Potent and selective class IIa HDAC inhibitor; brain penetrant | ||
| 7007 | PDD 00017238 | Dec 2019 |
| High affinity and potent PARG inhibitor | ||
| 7009 | PDD 00031705 | Dec 2019 |
| Negative control for PDD 00017238 (Cat. No. 7007). | ||
| 6586 | Targapremir 210 | Dec 2019 |
| Inhibits formation of miR-210 | ||
| 6991 | Poly Vinyl Alcohol | Dec 2019 |
| Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion | ||
| 6931 | AF 64394 | Dec 2019 |
| Potent and selective GPR3 inverse agonist | ||
| 7049 | Nintedanib | Dec 2019 |
| Potent VEGFR, PDGFR and FGFR inhibitor | ||
| 6860 | SB 290157 trifluoroacetate | Dec 2019 |
| Potent C3a receptor antagonist | ||
| 7071 | GSK 2239633A | Dec 2019 |
| Potent CCR4 antagonist | ||
| 7026 | Veliparib dihydrochloride | Dec 2019 |
| High affinity PARP-1 and -2 inhibitor; orally bioavailable | ||
| 7002 | KYA 1797K | Dec 2019 |
| Wnt/β-catenin signaling inhibitor | ||
| 6961 | FzM1.8 | Dec 2019 |
| Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness | ||
| 7053 | MM 07 | Dec 2019 |
| Apelin receptor biased agonist; exhibits bias for the G protein pathway | ||
| 6912 | dTAG-7 | Dec 2019 |
| First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation | ||
| 5860 | 7rh | Dec 2019 |
| Potent and selective DDR1 inhibitor; orally bioavailable | ||
| 6729 | TAN 452 | Dec 2019 |
| Potent and selective peripherally acting δ opioid antagonist; antianalgesic. | ||
| 6875 | TRPC6-PAM-C20 | Dec 2019 |
| Selective TRPC6 positive allosteric modulator | ||
| 6900 | NNMTi | Dec 2019 |
| Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation | ||
| 6981 | TL 0259 | Dec 2019 |
| Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable | ||
| 6799 | MB 0223 | Dec 2019 |
| Dynamin-related GTPase DRP1 partial inhibitor | ||
| 6775 | ST 045849 | Dec 2019 |
| O-GlcNAc transferase (OGT) inhibitor | ||
| 7050 | Ribociclib | Dec 2019 |
| Dual cdk4/cdk6 inhibitor; orally bioavailable | ||
| 7031 | Amyloid β-Peptide (1-37) (human) | Nov 2019 |
| Amyloid β-protein fragment | ||
| 7119 | Sorbic acid | Nov 2019 |
| Activator of hFFA2-DREADDs | ||
| 6472 | A 410099.1 amide-PEG3-amine | Nov 2019 |
| A 410099.1 amide-PEG3-amine | ||
| 6946 | Thalidomide 4'-oxyacetamide-alkylC8-amine | Nov 2019 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7070 | Mirabegron | Nov 2019 |
| Potent and selective β3 agonist | ||
| 6473 | A 410099.1 amide-PEG2-amine | Nov 2019 |
| A 410099.1 amide-PEG2-amine | ||
| 6474 | A 410099.1 amide-alkylC4-amine | Nov 2019 |
| A 410099.1 amide-alkylC4-amine | ||
| 6471 | A 410099.1, amine | Nov 2019 |
| Functionalized IAP ligand for PROTACs | ||
| 6971 | aTAG 4531 | Nov 2019 |
| Degrader of MTH1 fusion proteins for use within the aTAG system | ||
| 6863 | N6-Cyclohexyladenosine | Nov 2019 |
| High affinity A1 receptor agonist | ||
| 6870 | AZ 12799734 | Nov 2019 |
| Potent TGF-βRI inhibitor | ||
| 7013 | OptoBI-1 | Nov 2019 |
| Photoswitchable TRPC3/6/7 agonist | ||
| 7066 | RCGD 423 | Nov 2019 |
| gp130 modulator; activates JAK/STAT signaling | ||
| 7044 | (±)-α-Lipoic acid | Nov 2019 |
| Liquid-liquid phase separated condensate modifier; reduces stress granule formation | ||
| 4265 | AS 1842856 | Nov 2019 |
| Potent and selective Foxo1 inhibitor; orally bioavailable | ||
| 6481 | AP 14145 hydrochloride | Nov 2019 |
| KCa2 channel negative allosteric modulator | ||
| 6895 | VU 0424465 | Oct 2019 |
| Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity | ||
| 7065 | Kainic acid (synthetic) | Oct 2019 |
| Kainate agonist; excitant and neurotoxin | ||
| 6936 | VZ 185 | Oct 2019 |
| Potent and selective BRD7/9 Degrader | ||
| 6932 | VU 0467485 | Oct 2019 |
| Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant | ||
| 6897 | P110 | Oct 2019 |
| Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable | ||
| 6847 | TAT-GluA2 3Y | Oct 2019 |
| Inhibitor of AMPA receptor endocytosis | ||
| 6982 | Cyclosporin H | Oct 2019 |
| Enhances lentiviral transduction | ||
| 7045 | (±)-α-Lipoamide | Oct 2019 |
| Phase-separated condensate modifier; orally bioavailable | ||
| 6691 | LP 922056 | Oct 2019 |
| Notum inhibitor; activates Wnt signaling | ||
| 6574 | Fluorescein-NAD+ | Oct 2019 |
| Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays | ||
| 6974 | BMS 986094 | Oct 2019 |
| Prodrug of HCV RNA polymerase inhibitor 2'-C-methyl guanosine triphosphate; potent HCV replication inhibitor | ||
| 6940 | BTD | Oct 2019 |
| Selective TRPC5 activator | ||
| 6573 | Biotin-NAD+ | Oct 2019 |
| Biotinylated-NAD+; substrate for ADP-ribosylation | ||
| 7027 | LY 2033298 | Sep 2019 |
| Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic | ||
| 7046 | 1,6-Hexanediol | Sep 2019 |
| Tool for probing liquid-liquid phase separation | ||
| 7006 | PDD 00017272 | Sep 2019 |
| Potent PARG inhibitor | ||
| 6427 | Tafluprost | Sep 2019 |
| Very high affinity FP receptor agonist | ||
| 7005 | 4-Thiouridine | Sep 2019 |
| Photoreactive uridine analog for RNA sequencing | ||
| 6821 | ZAP 180013 | Sep 2019 |
| Zap70 inhibitor; inhibits interaction with ITAMs | ||
| 5847 | ZLD 1039 | Sep 2019 |
| Potent and selective EZH2 inhibitor; orally bioavailable | ||
| 6950 | Thalidomide 4'-ether-PEG3-amine | Sep 2019 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 6889 | ML 418 | Sep 2019 |
| Kir 7.1 inhibitor; also inhibits Kir 6.2 | ||
| 6764 | B 973B | Sep 2019 |
| Positive allosteric modulator of α7 nAChRs; analgesic | ||
| 6970 | aTAG 2139 | Sep 2019 |
| Degrader of MTH1 fusion proteins for use within the aTAG system | ||
| 6972 | A 1899 | Sep 2019 |
| Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker | ||
| 6797 | KLD 12 | Sep 2019 |
| Self-assembling peptide; forms hydrogel to support cell growth | ||
| 6893 | VU 6005649 | Sep 2019 |
| Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant | ||
| 6906 | BAY 293 Negative Control | Sep 2019 |
| Negative control for BAY 293 (Cat. No. 6857) | ||
| 6937 | BSJ-04-132 | Sep 2019 |
| Selective Cdk4 degrader | ||
| 6857 | BAY 293 | Sep 2019 |
| Potent KRas/SOS1 interaction inhibitor | ||
| 6803 | MRK 740 | Sep 2019 |
| Potent PRDM9 inhibitor | ||
| 6899 | TH 257 | Sep 2019 |
| Potent and selective allosteric LIMK 1/2 inhibitor | ||
| 6980 | BAY 87-2243 | Sep 2019 |
| Mitochondrial complex I inhibitor | ||
| 7020 | LDV | Sep 2019 |
| α4β1 (VLA-4) ligand | ||
| 6888 | ML 402 | Sep 2019 |
| Selective TREK channel activator |