New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7450 | SGC CK2-1 | Sep 2021 |
| Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2 | ||
| TB1099-RMU | Forskolin | Sep 2021 |
| Forskolin synthesised to Ancillary Material Grade | ||
| 7057 | VU 0071063 | Sep 2021 |
| Selective activator of SUR1 Kir6.2 channels | ||
| 7304 | JH-XI-10-02 | Sep 2021 |
| CDK8 Degrader (PROTAC®) | ||
| 6141 | BI-6901 | Sep 2021 |
| Potent and selective CCR10 antagonist | ||
| 6804 | Hoechst Janelia Fluor® 646 | Sep 2021 |
| Fluorogenic, red-emitting DNA probe | ||
| 7460 | SGC SMARCA-BRDVIII | Sep 2021 |
| Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor | ||
| 7321 | Pritelivir | Sep 2021 |
| Potent and selective herpes simplex virus (HSV) helicase primase inhibitor | ||
| 6687 | 1R,3R-RSL3 | Sep 2021 |
| Negative control for 1S,3R-RSL3 (Cat. No. 6118) | ||
| 6498 | TASP 0277308 | Sep 2021 |
| Potent and selective S1P1 receptor antagonist; inhibits angiogenesis | ||
| 7214 | VH 032 amide-PEG2-acid | Sep 2021 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| 7406 | Rf470DL | Sep 2021 |
| Blue rotor-fluorogenic fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 4894 | ML 299 | Sep 2021 |
| Potent inhibitor of PLD1 and PLD2; CNS penetrant | ||
| 5114 | K34c | Sep 2021 |
| Potent and selective α5β1 integrin inhibitor | ||
| 7421 | LC 2 Epimer | Sep 2021 |
| Negative control for LC 2 (Cat. No. 7420) | ||
| 7432 | SIM1 | Sep 2021 |
| Potent and selective trivalent BET Bromodomain Degrader (PROTAC®) | ||
| 7157 | YKL 5-124 | Sep 2021 |
| Potent and selective CDK7 inhibitor; induces cell cycle arrest | ||
| 7408 | OGDA | Sep 2021 |
| Green fluorescent D-amino acid; compatible with STED microscopy | ||
| 7373 | FNIR-Tag, NHS | Sep 2021 |
| Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester | ||
| 7139 | CeMMEC1 | Sep 2021 |
| TAF1 inhibitor | ||
| 6862 | Psoralen-triethylene glycol azide | Sep 2021 |
| RNA conformation probe; reagent for COMRADES RNA platform | ||
| 7309 | Vemurafenib | Sep 2021 |
| Potent BRAF and CRAF inhibitor | ||
| TB5758-RMU | AGN 193109 | Aug 2021 |
| AGN 193109 synthesized to Ancillary Material Grade | ||
| TB6053-RMU | LDN 193189 | Aug 2021 |
| LDN 193189 synthesized to Ancillary Material Grade | ||
| TB3000-RMU | Gefitinib | Aug 2021 |
| Iressa synthesized to Ancillary Material Grade | ||
| TB0760-RMU | AM 580 | Aug 2021 |
| AM 580 synthesized to Ancillary Material Grade | ||
| 7486 | Roxadustat | Aug 2021 |
| HIF-PH inhibitor; erythropoietic | ||
| 7426 | CG 428-Neg | Aug 2021 |
| Negative control for CG 428 (Cat. No. 7425) | ||
| 7425 | CG 428 | Aug 2021 |
| Potent tropomyosin receptor kinase (TRK) degrader | ||
| 7371 | Neratinib | Aug 2021 |
| Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor | ||
| 6497 | GSK 2833503A | Aug 2021 |
| Potent and selective TRPC6 and TRPC3 antagonist | ||
| 7320 | Methoxyluteolin | Aug 2021 |
| Inhibitor of pro-inflammatory mediator release from mast cells | ||
| 7375 | RO 8191 | Aug 2021 |
| IFNα receptor 2 agonist | ||
| 7194 | Erlotinib Hydrochloride | Aug 2021 |
| Potent, reversible EGFR tyrosine kinase inhibitor | ||
| 7420 | LC 2 | Aug 2021 |
| Selective KRAS PROTAC® | ||
| 7419 | Kyoto Probe-1 | Aug 2021 |
| Fluorescent probe that selectively identifies undifferentiated iPS/ES cells | ||
| 3345 | MLN 4760 | Aug 2021 |
| Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor | ||
| 4327 | JW 480 | Jul 2021 |
| Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1) | ||
| 7462 | ET 18-OCH3 | Jul 2021 |
| Selective PI-PLC inhibitor, also PAF receptor agonist | ||
| 7469 | Pomalidomide 5'-piperazine-4-methylpiperidine | Jul 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 6977 | Bobcat339 | Jul 2021 |
| Ten-eleven translocation methylcytosine dioxygenase (TET) inhibitor | ||
| 7471 | Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine | Jul 2021 |
| Cereblon ligand with terminal piperidine for onward chemistry | ||
| 7470 | Pomalidomide 5'-fluoro-6'-piperazine | Jul 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7464 | SJF 0661 | Jul 2021 |
| Negative control for SJF 0628 (Cat. No. 7463) | ||
| 7463 | SJF 0628 | Jul 2021 |
| Potent BRAF PROTAC® | ||
| 7428 | CG 858-Neg | Jul 2021 |
| Negative control for CG 858 (Cat. No. 7427) | ||
| 7427 | CG 858 | Jul 2021 |
| Selective BRAF-V600E protein Degrader (uSMITE™) | ||
| 7468 | Pomalidomide 5'-piperazine | Jul 2021 |
| Cereblon ligand with terminal piperazine for onward chemistry | ||
| 7313 | Hoechst Janelia Fluor® 526 | Jul 2021 |
| Fluorogenic, green-emitting DNA probe | ||
| 7030 | GW 280264X | Jul 2021 |
| Potent ADAM10 and ADAM17 inhibitor | ||
| 7054 | T4 | Jul 2021 |
| Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3 | ||
| 7153 | BRD 0539 | Jul 2021 |
| Cell permeable and reversible Cas9 inhibitor | ||
| 6018 | Nicotinamide Riboside | Jul 2021 |
| NAD+ precursor; substrate for nicotinamide riboside kinases | ||
| 7324 | Di 4 ANEPPS | Jun 2021 |
| Voltage-sensitive probe; used to detect changes in membrane potential in electrophysiology protocols | ||
| 7336 | Dinaciclib | Jun 2021 |
| Potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9 | ||
| 7391 | O-Propargyl-puromycin | Jun 2021 |
| Puromycin analog for labeling newly synthesized proteins; is incorporated into nascent polypeptides | ||
| 7439 | Pomalidomide 4'-alkylC2-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7407 | LEI 401 | Jun 2021 |
| High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor | ||
| 6941 | Pyr 10 | Jun 2021 |
| Selective TRPC3 inhibitor | ||
| 6848 | GSK 2795039 | Jun 2021 |
| NADPH oxidase 2 (NOX2) inhibitor | ||
| 7443 | Pomalidomide 4'-alkylC6-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7442 | Pomalidomide 4'-alkylC5-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7441 | Pomalidomide 4'-alkylC4-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7452 | FAM-DEALAHypYIPMDDDFQLRSF | Jun 2021 |
| Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity | ||
| 7440 | Pomalidomide 4'-alkylC3-azide | Jun 2021 |
| Cereblon ligand with alkyl linker and terminal azide for onward chemistry | ||
| 7438 | Pomalidomide 4'-PEG6-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7401 | tri-GalNAc COOH | Jun 2021 |
| Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry | ||
| 7437 | Pomalidomide 4'-PEG5-azide | Jun 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7414 | DSRM-3716 | Jun 2021 |
| Potent and reversible SARM1 NAD hydrolase inhibitor | ||
| 7403 | Thalidomide 4'-ether-alkylC8-amine | May 2021 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6871 | MO-I-500 | May 2021 |
| FTO inhibitor; anticonvulsant | ||
| 7129 | RA 2 | May 2021 |
| Potent negative modulator of KCa2.3 and KCa3.1 channels | ||
| 7295 | SMCy 5.5 | May 2021 |
| Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy | ||
| 7314 | Pepstatin A Janelia Fluor® 526 | May 2021 |
| Fluorogenic green-emitting lysosome tracker and stain | ||
| 7315 | Taxol Janelia Fluor® 526 | May 2021 |
| Green fluorescent taxol derivative; probe for microtubule staining | ||
| 7240 | ZNL 02-096 | May 2021 |
| Potent and selective Wee1 Degrader (PROTAC®) | ||
| 7342 | Emetine dihydrochloride | May 2021 |
| RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika | ||
| 7306 | FC 11 | May 2021 |
| Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®) | ||
| 7275 | Laurdan | May 2021 |
| Polarity sensitive lipid membrane fluorescent probe; used to imaging lipid rafts | ||
| 5985 | AKT Inhibitor IV | May 2021 |
| Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates | ||
| 7436 | Pomalidomide 4'-PEG4-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7435 | Pomalidomide 4'-PEG3-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7434 | Pomalidomide 4'-PEG1-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7307 | Pomalidomide 4'-PEG2-azide | May 2021 |
| Cereblon ligand with PEG linker and terminal azide for onward chemistry | ||
| 7404 | VH 032 amide-alkylC9-acid | May 2021 |
| VHL ligand with alkyl linker and terminal acid for onward chemistry | ||
| 7135 | AKOS 022 | May 2021 |
| Voltage-dependent anion channel (VDAC) inhibitor | ||
| 7055 | WS 383 | May 2021 |
| Potent, selective and reversible DCN1-UBC12 interaction inhibitor | ||
| 7387 | Nile Red | May 2021 |
| Fluorogenic lipid membrane dye | ||
| 6738 | KT 182 | May 2021 |
| Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor | ||
| 7229 | Galidesivir dihydrochloride | Apr 2021 |
| Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral | ||
| 7218 | PZM21 | Apr 2021 |
| Selective μ receptor agonist | ||
| 7134 | ARN 14494 | Apr 2021 |
| Potent serine palmitoyltransferase inhibitor | ||
| 7271 | Brivaracetam | Apr 2021 |
| SV2A ligand; antiepileptic | ||
| 7390 | Tissue Clearing Pro-Organoid | Apr 2021 |
| 3D cell culture clearing reagent kit | ||
| 7389 | Tissue Clearing Pro | Apr 2021 |
| Tissue clearing reagent kit | ||
| 6975 | Teniposide | Apr 2021 |
| DNA topoisomerase II inhibitor; viral transduction enhancer | ||
| 7402 | TAT-Gap19(I130A) | Apr 2021 |
| Control peptide for TAT-Gap19 | ||
| 7289 | Nimbolide | Apr 2021 |
| RNF114 inhibitor | ||
| 7316 | Janelia Fluor 526®, SE | Apr 2021 |
| Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm | ||
| 6973 | NS 3728 | Apr 2021 |
| VRAC blocker | ||
| 4687 | ML 252 | Apr 2021 |
| Potent and selective KV7.2 inhibitor; brain penetrant | ||
| 7396 | MS 154N | Mar 2021 |
| Negative control for MS 154 (Cat No. 7395) | ||
| 7398 | MS 39N | Mar 2021 |
| Negative control for MS 39 (Cat. No. 7397) | ||
| 7395 | MS 154 | Mar 2021 |
| Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR |