New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat. No. Product Name / Activity Date Added
7064 Ruxolitinib Feb 2020
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
7121 7-Aminoactinomycin D Feb 2020
Fluorescent DNA stain
7162 iFSP1 Feb 2020
Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer
7038 Palonosetron hydrochloride Feb 2020
Highly potent and high affinity 5-HT3 antagonist
6928 VU 6001966 Feb 2020
Potent and selective mGlu2 negative allosteric modulator
7088 Janelia Fluor® 646, Azide Feb 2020
Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging
6833 RO 5263397 hydrochloride Feb 2020
Potent TA1 receptor agonist
7039 SK 609 Feb 2020
Dopamine D3 receptor biased agonist
6791 BC-LI-0186 Feb 2020
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
6110 HJC 0416 hydrochloride Feb 2020
STAT3 inhibitor
6993 Janelia Fluor® 646, free acid Feb 2020
Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging
5746 NESS 0327 Feb 2020
Ultra-high affinity and selective CB1 antagonist
7040 C 176 Feb 2020
mSTING antagonist
7150 Tocriscreen 2.0 Max Jan 2020
A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions)
6457 Cyanine 3 Tyramide Jan 2020
Orange fluorescent reagent widely used for signal amplification in IHC and ISH
6220 PM 226 Jan 2020
Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective
6456 Fluorescein Tyramide Jan 2020
Green fluorescent reagent widely used for signal amplification in IHC and ISH
7015 IA-Alkyne Jan 2020
Broad spectrum cysteine reactive probe
6458 Cyanine 5 Tyramide Jan 2020
Red fluorescent reagent widely used for signal amplification in IHC and ISH
6398 SKA 121 Jan 2020
Positive allosteric modulator of KCa3.1 channels
TB3748-GMP XAV 939 Jan 2020
XAV 939 synthesized to cGMP guidelines
6858 MMG 11 Jan 2020
TLR2 antagonist
6925 NBC 6 Jan 2020
NLRP3 inflammasome inhibitor
7152 Tocriscreen 2.0 Micro Jan 2020
A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
7151 Tocriscreen 2.0 Mini Jan 2020
A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions)
6985 VH 032 amide-alkylC5-amine Jan 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7051 Tasquinimod Jan 2020
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
6964 LY 2119620 Jan 2020
Positive allosteric modulator of M2 and M4 receptors
6952 VH 101, phenol Jan 2020
Hydroxyl functionalized VHL ligand
6725 CHDI 00390576 Dec 2019
Potent and selective class IIa HDAC inhibitor; brain penetrant
7007 PDD 00017238 Dec 2019
High affinity and potent PARG inhibitor
7009 PDD 00031705 Dec 2019
Negative control for PDD 00017238 (Cat. No. 7007).
6586 Targapremir 210 Dec 2019
Inhibits formation of miR-210
6991 Poly Vinyl Alcohol Dec 2019
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
6931 AF 64394 Dec 2019
Potent and selective GPR3 inverse agonist
7049 Nintedanib Dec 2019
Potent VEGFR, PDGFR and FGFR inhibitor
6860 SB 290157 trifluoroacetate Dec 2019
Potent C3a receptor antagonist
7071 GSK 2239633A Dec 2019
Potent CCR4 antagonist
7026 Veliparib dihydrochloride Dec 2019
High affinity PARP-1 and -2 inhibitor; orally bioavailable
7002 KYA 1797K Dec 2019
Wnt/β-catenin signaling inhibitor
6961 FzM1.8 Dec 2019
Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness
7053 MM 07 Dec 2019
Apelin receptor biased agonist; exhibits bias for the G protein pathway
6912 dTAG-7 Dec 2019
First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
5860 7rh Dec 2019
Potent and selective DDR1 inhibitor; orally bioavailable
6729 TAN 452 Dec 2019
Potent and selective peripherally acting δ opioid antagonist; antianalgesic.
6875 TRPC6-PAM-C20 Dec 2019
Selective TRPC6 positive allosteric modulator
6900 NNMTi Dec 2019
Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
6981 TL 0259 Dec 2019
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
6799 MB 0223 Dec 2019
Dynamin-related GTPase DRP1 partial inhibitor
6775 ST 045849 Dec 2019
O-GlcNAc transferase (OGT) inhibitor
7050 Ribociclib Dec 2019
Dual cdk4/cdk6 inhibitor; orally bioavailable
7031 Amyloid β-Peptide (1-37) (human) Nov 2019
Amyloid β-protein fragment
7119 Sorbic acid Nov 2019
Activator of hFFA2-DREADDs
6472 A 410099.1 amide-PEG3-amine Nov 2019
A 410099.1 amide-PEG3-amine
6946 Thalidomide 4'-oxyacetamide-alkylC8-amine Nov 2019
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7070 Mirabegron Nov 2019
Potent and selective β3 agonist
6473 A 410099.1 amide-PEG2-amine Nov 2019
A 410099.1 amide-PEG2-amine
6474 A 410099.1 amide-alkylC4-amine Nov 2019
A 410099.1 amide-alkylC4-amine
6471 A 410099.1, amine Nov 2019
Functionalized IAP ligand for PROTACs
6971 aTAG 4531 Nov 2019
Degrader of MTH1 fusion proteins for use within the aTAG system
6863 N6-Cyclohexyladenosine Nov 2019
High affinity A1 receptor agonist
6870 AZ 12799734 Nov 2019
Potent TGF-βRI inhibitor
7013 OptoBI-1 Nov 2019
Photoswitchable TRPC3/6/7 agonist
7066 RCGD 423 Nov 2019
gp130 modulator; activates JAK/STAT signaling
7044 (±)-α-Lipoic acid Nov 2019
Liquid-liquid phase separated condensate modifier; reduces stress granule formation
4265 AS 1842856 Nov 2019
Potent and selective Foxo1 inhibitor; orally bioavailable
6481 AP 14145 hydrochloride Nov 2019
KCa2 channel negative allosteric modulator
6895 VU 0424465 Oct 2019
Potent mGlu5 positive allosteric modulator and agonist; binds allosteric site with high affinity
7065 Kainic acid (synthetic) Oct 2019
Kainate agonist; excitant and neurotoxin
6936 VZ 185 Oct 2019
Potent and selective BRD7/9 Degrader
6932 VU 0467485 Oct 2019
Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant
6897 P110 Oct 2019
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
6847 TAT-GluA2 3Y Oct 2019
Inhibitor of AMPA receptor endocytosis
6982 Cyclosporin H Oct 2019
Enhances lentiviral transduction
7045 (±)-α-Lipoamide Oct 2019
Phase-separated condensate modifier; orally bioavailable
6691 LP 922056 Oct 2019
Notum inhibitor; activates Wnt signaling
6574 Fluorescein-NAD+ Oct 2019
Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays
6974 BMS 986094 Oct 2019
Prodrug of HCV RNA polymerase inhibitor 2'-C-methyl guanosine triphosphate; potent HCV replication inhibitor
6940 BTD Oct 2019
Selective TRPC5 activator
6573 Biotin-NAD+ Oct 2019
Biotinylated-NAD+; substrate for ADP-ribosylation
7027 LY 2033298 Sep 2019
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
7046 1,6-Hexanediol Sep 2019
Tool for probing liquid-liquid phase separation
7006 PDD 00017272 Sep 2019
Potent PARG inhibitor
6427 Tafluprost Sep 2019
Very high affinity FP receptor agonist
7005 4-Thiouridine Sep 2019
Photoreactive uridine analog for RNA sequencing
6821 ZAP 180013 Sep 2019
Zap70 inhibitor; inhibits interaction with ITAMs
5847 ZLD 1039 Sep 2019
Potent and selective EZH2 inhibitor; orally bioavailable
6950 Thalidomide 4'-ether-PEG3-amine Sep 2019
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6889 ML 418 Sep 2019
Kir 7.1 inhibitor; also inhibits Kir 6.2
6764 B 973B Sep 2019
Positive allosteric modulator of α7 nAChRs; analgesic
6970 aTAG 2139 Sep 2019
Degrader of MTH1 fusion proteins for use within the aTAG system
6972 A 1899 Sep 2019
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
6797 KLD 12 Sep 2019
Self-assembling peptide; forms hydrogel to support cell growth
6893 VU 6005649 Sep 2019
Positive allosteric modulators of mGlu7 and mGlu8 receptors; also NK1 antagonist; brain penetrant
6906 BAY 293 Negative Control Sep 2019
Negative control for BAY 293 (Cat. No. 6857)
6937 BSJ-04-132 Sep 2019
Selective Cdk4 degrader
6857 BAY 293 Sep 2019
Potent KRas/SOS1 interaction inhibitor
6803 MRK 740 Sep 2019
Potent PRDM9 inhibitor
6899 TH 257 Sep 2019
Potent and selective allosteric LIMK 1/2 inhibitor
6980 BAY 87-2243 Sep 2019
Mitochondrial complex I inhibitor
7020 LDV Sep 2019
α4β1 (VLA-4) ligand
6888 ML 402 Sep 2019
Selective TREK channel activator