New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
6848 GSK 2795039 Jun 2021
NADPH oxidase 2 (NOX2) inhibitor
7443 Pomalidomide 4'-alkylC6-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7442 Pomalidomide 4'-alkylC5-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7441 Pomalidomide 4'-alkylC4-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7414 DSRM-3716 Jun 2021
Potent and reversible SARM1 NAD hydrolase inhibitor
7401 tri-GalNAc COOH Jun 2021
Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
7452 FAM-DEALAHypYIPMDDDFQLRSF Jun 2021
Fluorescent HIF-1α peptide; can be used to evaluate the effect of VHL binding on degradation activity
7440 Pomalidomide 4'-alkylC3-azide Jun 2021
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7438 Pomalidomide 4'-PEG6-azide Jun 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7437 Pomalidomide 4'-PEG5-azide Jun 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7403 Thalidomide 4'-ether-alkylC8-amine May 2021
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6871 MO-I-500 May 2021
FTO inhibitor; anticonvuslant
7129 RA 2 May 2021
Potent negative modulator of KCa2.3 and KCa3.1 channels
7295 SMCy 5.5 May 2021
Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
7306 FC 11 May 2021
Highly potent focal adhesion kinase (FAK) Degrader (PROTAC®)
7342 Emetine dihydrochloride May 2021
RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
7314 Pepstatin A Janelia Fluor® 526 May 2021
Fluorogenic green-emitting lysosome probe
7315 Taxol Janelia Fluor® 526 May 2021
Green fluorescent taxol derivative; probe for microtubule staining
7240 ZNL 02-096 May 2021
Potent and selective Wee1 Degrader (PROTAC®)
7275 Laurdan May 2021
Polarity sensitive lipid membrane fluorescent probe
5985 AKT Inhibitor IV May 2021
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
7436 Pomalidomide 4'-PEG4-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7404 VH 032 amide-alkylC9-acid May 2021
VHL ligand with alkyl linker and terminal acid for onward chemistry
7307 Pomalidomide 4'-PEG2-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7435 Pomalidomide 4'-PEG3-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7434 Pomalidomide 4'-PEG1-azide May 2021
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7135 AKOS 022 May 2021
Voltage-dependent anion channel (VDAC) inhibitor
7055 WS 383 May 2021
Potent, selective and reversible DCN1-UBC12 interaction inhibitor
7387 Nile Red May 2021
Fluorogenic lipid membrane dye
6738 KT 182 May 2021
Potent, selective and irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor
7218 PZM21 Apr 2021
Selective μ receptor agonist
7229 Galidesivir dihydrochloride Apr 2021
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
7134 ARN 14494 Apr 2021
Potent serine palmitoyltransferase inhibitor
7271 Brivaracetam Apr 2021
SV2A ligand; antiepileptic
7390 Tissue Clearing Pro-Organoid Apr 2021
3D cell culture clearing reagent kit
7389 Tissue Clearing Pro Apr 2021
Tissue clearing reagent kit
7402 TAT-Gap19(I130A) Apr 2021
Control peptide for TAT-Gap19
7289 Nimbolide Apr 2021
RNF114 inhibitor
7316 Janelia Fluor 526®, SE Apr 2021
Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
6975 Teniposide Apr 2021
DNA topoisomerase II inhibitor; viral transduction enhancer
6973 NS 3728 Apr 2021
VRAC blocker
4687 ML 252 Apr 2021
Potent and selective KV7.2 inhibitor; brain penetrant
7396 MS 154N Mar 2021
Negative control for MS 154 (Cat No. 7395)
7398 MS 39N Mar 2021
Negative control for MS 39 (Cat. No. 7397)
7395 MS 154 Mar 2021
Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR
TB3742-RMU RepSox Mar 2021
RepSox synthesized to Ancillary Material Grade
TB4855-RMU WIKI4 Mar 2021
WIKI4 synthesized to Ancillary Material Grade
TB2634-RMU DAPT Mar 2021
DAPT synthesized to Ancillary Material Grade
7328 Photo-lenalidomide-acid Mar 2021
Functionalized photoswitchable cereblon ligand for Degraders
7003 NAI-N3 Mar 2021
Reagent for RNA icSHAPE experiments in vivo
7372 CDK8/19i Mar 2021
Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
7340 Tocriscreen Stem Cell Library Mar 2021
A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling
7397 MS 39 Mar 2021
Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR
7118 cis-22a Mar 2021
TRPV6 inhibitor
7120 SNIPER(ER)-87 Mar 2021
Potent and selective ERα Degrader (SNIPER)
6499 MLN 4924 Mar 2021
Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable
7388 ND1-YL2 Feb 2021
SRC-1 peptide-based PROTAC®; active in vivo
7319 BRD PHOTAC-I-3 Feb 2021
Photoswitchable BET bromodomain Degrader (PHOTAC)
7033 AY 77 Feb 2021
Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling
7195 MCU i4 Feb 2021
Negative modulator of mitochondrial Ca2+ uniporter (MCU)
7217 VH 032 amide-alkylC5-acid Feb 2021
VHL ligand with alkyl linker and terminal acid for onward chemistry
6741 GW 4869 Feb 2021
Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor
7366 WM 3835 Feb 2021
Lysine acetyltransferase HBO1 (KAT7) inhibitor
7034 AY 254 Feb 2021
Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling
7265 GMB 475 Feb 2021
BCR-ABL1 kinase PROTAC®
7256 ARV 771 Feb 2021
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
6693 WM 8014 Feb 2021
Potent and selective KAT6A and KAT6B inhibitor
7374 dTAGV-1 hydrochloride Jan 2021
Hydrochloride salt of dTAGV-1 (Cat. No. 6914); suitable for in vivo use
7273 C-Laurdan Jan 2021
Two-photon polarity-sensitive lipid membrane probe
7175 DOPE Jan 2021
Liposome/lipoplex transfection enhancer
7282 Bortezomib Jan 2021
High affinity proteasome inhibitor
7268 SJFα Jan 2021
Potent and selective p38α PROTAC®
7192 SMIP 004 Jan 2021
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
7352 YM 254890 Jan 2021
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling
6261 VCP 171 Jan 2021
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
7377 BIIE 0246 hydrochloride Dec 2020
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
7216 VH 032 amide-alkylC3-acid Dec 2020
VHL ligand with alkyl linker and terminal acid for onward chemistry
7267 SJFδ Dec 2020
Potent and selective p38δ PROTAC®
7266 SJF 8240 Dec 2020
c-MET PROTAC®; also degrades exon-14-deleted c-MET