New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

If you can't find what you are looking for we welcome new product suggestions. If you would like to be kept informed about new products by email, please sign up for our monthly e-alert service.

Cat. No. Product Name / Activity Date Added
7316 Janelia Fluor 526®, SE Apr 2021
Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
6975 Teniposide Apr 2021
DNA topoisomerase II inhibitor; viral transduction enhancer
7402 TAT-Gap19(I130A) Apr 2021
Control peptide for TAT-Gap19
7289 Nimbolide Apr 2021
RNF114 inhibitor
6973 NS 3728 Apr 2021
VRAC blocker
4687 ML 252 Apr 2021
Potent and selective KV7.2 inhibitor; brain penetrant
7396 MS 154N Mar 2021
Negative control for MS 154 (Cat No. 7395)
7398 MS 39N Mar 2021
Negative control for MS 39 (Cat. No. 7397)
7395 MS 154 Mar 2021
Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR
TB3742-RMU RepSox Mar 2021
RepSox synthesized to Ancillary Material Grade
TB4855-RMU WIKI4 Mar 2021
WIKI4 synthesized to Ancillary Material Grade
TB2634-RMU DAPT Mar 2021
DAPT synthesized to Ancillary Material Grade
7003 NAI-N3 Mar 2021
Reagent for RNA icSHAPE experiments in vivo
7328 Photo-lenalidomide-acid Mar 2021
Functionalized photoswitchable cereblon ligand for Degraders
7325 Human LAMP primers (18S rRNA) Mar 2021
LAMP primer set for use as positive control in RT-LAMP assays for SARS-CoV-2 detection
7327 SARS-CoV-2 LAMP primers (ORF1a) Mar 2021
LAMP primer set for SARS CoV-2, which targets ORF1a
7326 SARS-CoV-2 LAMP primers (N gene) Mar 2021
LAMP primer set for SARS CoV-2, which targets N gene
7397 MS 39 Mar 2021
Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR
7118 cis-22a Mar 2021
TRPV6 inhibitor
7372 CDK8/19i Mar 2021
Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
7340 Tocriscreen Stem Cell Library Mar 2021
A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling
7120 SNIPER(ER)-87 Mar 2021
Potent and selective ERα Degrader (SNIPER)
6499 MLN 4924 Mar 2021
Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable
7388 ND1-YL2 Feb 2021
SRC-1 peptide-based PROTAC®; active in vivo
7319 BRD PHOTAC-I-3 Feb 2021
Photoswitchable BET bromodomain Degrader (PHOTAC)
7033 AY 77 Feb 2021
Potent PAR2 biased agonist; exhibits bias for Ca2+ signaling
7217 VH 032 amide-alkylC5-acid Feb 2021
VHL ligand with alkyl linker and terminal acid for onward chemistry
7195 MCU i4 Feb 2021
Negative modulator of mitochondrial Ca2+ uniporter (MCU)
6741 GW 4869 Feb 2021
Selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor
7034 AY 254 Feb 2021
Potent PAR2 biased agonist; exhibits bias for ERK1/2 signaling
7265 GMB 475 Feb 2021
BCR-ABL1 kinase PROTAC®
7366 WM 3835 Feb 2021
Lysine acetyltransferase HBO1 (KAT7) inhibitor
7256 ARV 771 Feb 2021
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
6693 WM 8014 Feb 2021
Potent and selective KAT6A and KAT6B inhibitor
7273 C-Laurdan Jan 2021
Two-photon polarity-sensitive lipid membrane probe
7175 DOPE Jan 2021
Liposome/lipoplex transfection enhancer
7374 dTAGV-1 hydrochloride Jan 2021
Hydrochloride salt of dTAGV-1 (Cat. No. 6914); suitable for in vivo use
7282 Bortezomib Jan 2021
High affinity proteasome inhibitor
7268 SJFα Jan 2021
Potent and selective p38α PROTAC®
7192 SMIP 004 Jan 2021
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
7352 YM 254890 Jan 2021
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling
6261 VCP 171 Jan 2021
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
7216 VH 032 amide-alkylC3-acid Dec 2020
VHL ligand with alkyl linker and terminal acid for onward chemistry
7267 SJFδ Dec 2020
Potent and selective p38δ PROTAC®
7377 BIIE 0246 hydrochloride Dec 2020
Potent, selective and competitive non-peptide NPY Y2 receptor antagonist; active in vivo
7266 SJF 8240 Dec 2020
c-MET PROTAC®; also degrades exon-14-deleted c-MET
7228 MPro 13b Dec 2020
Coronavirus Mpro inhibitor
7312 HM Janelia Fluor® 526, SE Dec 2020
Fluorogenic spontaneously blinking green-emitting dye; for SMLSM; λabsλem 526/550 nm
7184 SGC 6870N Dec 2020
Negative control for SGC 6870 (Cat. No. 7182)
7182 SGC 6870 Dec 2020
Potent and selective PRMT6 inhibitor
7370 3-Aminotyrosine Dec 2020
Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors
7353 MSA 2 Dec 2020
Non-nucleotide STING agonist; orally bioavailable
7322 SP 10 Dec 2020
Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
6990 SET 2 Dec 2020
Selective TRPV2 antagonist
7338 K 22 Dec 2020
Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation
7156 WQ 1 Dec 2020
Potent and selective σ1 receptor antagonist; active in vivo
7073 VH 032 amide-alkylC3-amine Dec 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7131 TM 38837 Dec 2020
Highly potent CB1 inverse agonist; peripherally restricted
6562 BAY 707 Dec 2020
Potent and selective MTH1 inhibitor
7105 VH 032 amide-PEG5-acid Nov 2020
VHL ligand with PEG linker and terminal acid for onward chemistry
7258 Gefitinib-based PROTAC® 3 Nov 2020
Potent EGFR PROTAC®
7255 ARCC 4 negative control Nov 2020
Negative control for ARCC 4 (Cat. No. 7254)
7197 JHU 37152 Nov 2020
High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
7303 iHAP1 Nov 2020
Allosteric activator of protein phosphatase 2A (PP2A)
7254 ARCC 4 Nov 2020
Potent and selective androgen receptor PROTAC®
7213 Pomalidomide 4'-PEG4-acid Nov 2020
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7260 TBK1 control PROTAC® 4 Nov 2020
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)
7302 Sulfo-NHS-LC-Biotin Nov 2020
Amine reactive biotinylation reagent, cell impermeable
5927 NS 383 Nov 2020
ASIC blocker; active in vivo
6322 LW 6 Nov 2020
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
7259 TBK1 PROTAC® 3i Nov 2020
Potent TANK-binding kinase 1 (TBK1) PROTAC®
7198 JHU 37160 Nov 2020
High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
7357 PLpro inhibitor 6 Oct 2020
SARS-CoV and SARS-CoV-2 PLpro inhibitor
7199 (±)-Eriodictyol Oct 2020
Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling
7294 VH 101 phenol-alkylC6-amine Oct 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7059 GLPG 0187 Oct 2020
Potent αv integrin inhibitor
7193 Deschloroclozapine Oct 2020
High affinity and highly potent activator of hM3Dq and hM4Di DREADDs; rapidly blood brain barrier penetrant
7329 Thalidomide 4'-ether-alkylC2-acid Oct 2020
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7106 VH 032 amide-alkylC2-acid Oct 2020
VHL ligand with alkyl linker and terminal acid for onward chemistry
7350 Tocriscreen Antiviral Library Oct 2020
Antiviral compound library for high throughput screening, chemical biology applications and drug repurposing; contains 240 bioactive compounds (100 μL 10 mM DMSO solutions)
7219 CRBN PROTAC® 14a Oct 2020
Cereblon Degrader (PROTAC®)
7188 Carfilzomib Oct 2020
Potent irreversible proteasome inhibitor; active in vivo