New ProductsView all new products by date added
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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7736 | Thalidomide 5'-amine-PEG2-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7735 | Thalidomide 5'-amine-PEG1-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7737 | Thalidomide 5'-amine-PEG3-amine | Jul 2022 |
| Cereblon ligand with PEG linker and terminal amine for onward chemistry | ||
| 7712 | Semax | Jun 2022 |
| Reduces Aβ aggregation and fibrillogenesis; neuroprotective and neurotrophic peptide | ||
| 7196 | Indinavir sulfate | Jun 2022 |
| Potent and selective HIV-1 and HIV-2 protease inhibitor | ||
| 7733 | Thalidomide 5'-amine-alkylC10-amine | Jun 2022 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7629 | Panobinostat | Jun 2022 |
| Pan-histone deacetylase inhibitor | ||
| 7510 | Indocyanine green | Jun 2022 |
| Near-infrared fluorescent dye | ||
| 7670 | Phenyl-glutarimide 4'-oxyacetic acid | Jun 2022 |
| Functionalized cereblon ligand for PROTAC development | ||
| 7701 | RAGE 229 | Jun 2022 |
| ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice | ||
| 7675 | SJ 1008030 | Jun 2022 |
| Selective JAK2 Degrader (PROTAC®) | ||
| 6923 | AMZ 30 | Jun 2022 |
| Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor | ||
| 7684 | Rilpivirine | May 2022 |
| Non-nucleoside reverse transcriptase inhibitor | ||
| 7635 | tri-GalNAc biotin | May 2022 |
| Biotinylated ASGPR ligand for LYTAC research and development | ||
| 6878 | BMS 466442 | May 2022 |
| Potent and selective inhibitor of asc-1 | ||
| 7679 | RECTAS | May 2022 |
| IKBKAP pre-mRNA splicing modulator | ||
| 7588 | SK 575-NEG | May 2022 |
| Negative control for SK 575 (Cat. No. 7583) | ||
| 7557 | Thalidomide 5'-amine-alkylC8-amine | May 2022 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7723 | RGD peptide | May 2022 |
| Minimal recognition sequence for integrin binding; potent integrin inhibitor | ||
| 7650 | AZD 2858 | May 2022 |
| Highly potent GSK-3 inhibitor; inhibits tau phosphorylation | ||
| 6529 | SGC AAK1 1N | May 2022 |
| Negative control for SGC AAK1 1 (Cat.No. 6528) | ||
| 6604 | VER 246608 | May 2022 |
| Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 /4 inhibitor | ||
| 7640 | Tucatinib | May 2022 |
| Potent and selective ErbB2 inhibitor | ||
| 7530 | dTAG-47 | May 2022 |
| Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation | ||
| 7392 | 5-Ph-IAA | May 2022 |
| Selective and potent TAG Degrader for auxin-inducible degron 2 system | ||
| 7446 | SCOTfluor 510, fluoro | May 2022 |
| Amine-reactive fluorescent probe precursor | ||
| 7696 | Selpercatinib | May 2022 |
| Potent and selective RET inhibitor | ||
| 7531 | dTAG-47-NEG | May 2022 |
| Negative control for dTAG-47 (Cat. No. 7530) | ||
| 7714 | EDA-DA | May 2022 |
| Unnatural dipeptide building block with alkyne group for functionalizing peptidoglycan | ||
| 7278 | α1A-AR Degrader 9c | May 2022 |
| Selective α1A adrenergic receptor Degrader (PROTAC®) | ||
| 7680 | ABT 263 | May 2022 |
| High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor | ||
| 7663 | Ozanimod | May 2022 |
| Potent and selective S1P1 and S1P5 agonist | ||
| 7689 | (+)-JQ1 bump, acid functionalized | May 2022 |
| Functionalized BET bromodomain ligand; precursor for Tag Degraders | ||
| 7583 | SK 575 | May 2022 |
| Potent PARP1 Degrader (PROTAC®) | ||
| 7339 | RIPA 56 | May 2022 |
| Potent and metabolically stable RIP1 kinase inhibitor | ||
| 7137 | Cambinol | May 2022 |
| nSMase2 inhibitor | ||
| 7215 | VH 032 amide-PEG4-acid | May 2022 |
| VHL ligand with PEG linker and terminal acid for onward chemistry | ||
| TB6666-RMU | T3 | May 2022 |
| T3 synthesized to Ancillary Material Grade | ||
| TB2939-RMU | A 83-01 | May 2022 |
| A 83-01 synthesized to Ancillary Material Grade | ||
| 7641 | Mito-HE | May 2022 |
| Fluorescent mitochondrial superoxide indicator in live cells | ||
| 7492 | Lomitapide mesylate | May 2022 |
| Potent microsomal triglyceride transfer protein (MTP) inhibitor | ||
| 7494 | CIA 1 | Apr 2022 |
| COUP-TFII inhibitor | ||
| 7652 | Linsitinib | Apr 2022 |
| Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor | ||
| 7659 | Verubecestat | Apr 2022 |
| BACE1 and BACE2 inhibitor | ||
| 7122 | Thioflavin T | Apr 2022 |
| Fluorescent amyloid stain, binds to the stacked β sheets of amyloid fibrils | ||
| 7553 | Ac4ManNDAz | Apr 2022 |
| Photo-crosslinking probe for studying glycoproteins and glycolipids | ||
| 7485 | Covidcil-19 | Apr 2022 |
| Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency | ||
| 7726 | DMSO, Cell Cryopreserve Grade | Apr 2022 |
| Intracellular cryoprotective agent | ||
| 7532 | CSN5i-3-NEG | Apr 2022 |
| Negative control for CSN5i-3 (Cat. No. 7089) | ||
| 7089 | CSN5i-3 | Apr 2022 |
| Potent and selective CSN5 (COP9 signalosome) inhibitor | ||
| TB6053-GMP | LDN 193189 | Apr 2022 |
| LDN 193189 synthesized to cGMP guidelines | ||
| 7687 | BromoTag® cis-AGB1 | Apr 2022 |
| Negative control for BromoTag® AGB1 (Cat.No. 7686) | ||
| 7686 | BromoTag® AGB1 | Apr 2022 |
| Potent and selective Degrader of Brd4BD2 L387A fusion proteins (BromoTag®) | ||
| 7512 | 3-Bromopyruvate | Apr 2022 |
| MCT1 inhibitor; also inhibits hexokinase II | ||
| 7590 | Pexidartinib | Apr 2022 |
| Potent CSF-1R inhibitor | ||
| 7376 | 2A3 | Mar 2022 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable | ||
| TB1285-RMU | Staurosporine | Mar 2022 |
| Staurosporine synthesized to Ancillary Material Grade | ||
| 7498 | SPOP-i-6lc | Mar 2022 |
| SPOP E3 ubiquitin ligase inhibitor | ||
| 7542 | SJ 1008066 | Mar 2022 |
| MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction | ||
| 7483 | BDY FL VH032 | Mar 2022 |
| High-affinity VHL fluorescent probe for TR-FRET and FP assays | ||
| 7010 | EM 163 | Mar 2022 |
| TIR-TIR interaction inhibitor | ||
| 7201 | Phalloidin-Janelia Fluor® 646 | Mar 2022 |
| Red fluorescent F-actin probe | ||
| 7667 | Pimavanserin | Mar 2022 |
| Selective 5-HT2A inverse agonist | ||
| 7586 | Molnupiravir | Mar 2022 |
| Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection | ||
| 7362 | Phototrexate | Mar 2022 |
| Photoswitchable inhibitor of human dihydrofolate reductase | ||
| 7630 | Pridopidine | Mar 2022 |
| Highly selective σ1 agonist | ||
| 2395 | Sertraline hydrochloride | Mar 2022 |
| 5-HT reuptake inhibitor | ||
| TB4439-RMU | ISX 9 | Mar 2022 |
| ISX 9 synthesized to Ancillary Material Grade | ||
| 7682 | JQAD1 | Feb 2022 |
| Potent and selective EP300 Degrader | ||
| 7488 | MRTX 849 | Feb 2022 |
| Mutation-selective inhibitor of KRASG12C | ||
| 7584 | iP300v | Feb 2022 |
| Negative control for iP300w (Cat. No. 7270) | ||
| 7589 | Adavosertib | Feb 2022 |
| Potent and selective Wee1 inhibitor | ||
| 7631 | Idelalisib | Feb 2022 |
| Potent PI 3-Kinase δ isoform inhibitor | ||
| 7018 | CBR-470-1 | Feb 2022 |
| PGK1 inhibitior; activates Nrf2 | ||
| 7507 | Evofosfamide | Feb 2022 |
| Hypoxia-activated DNA alkylating agent prodrug | ||
| 7591 | CB 839 | Jan 2022 |
| Potent glutaminase GLS1 inhibitor | ||
| 7457 | CAM 833 | Jan 2022 |
| Selective orthosteric inhibitor of the BRCA2-RAD51 interaction | ||
| 7578 | Tocriscreen Epigenetics 3.0 | Jan 2022 |
| A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening and chemical biology applications | ||
| 7579 | Olaparib | Jan 2022 |
| Potent PARP inhibitor | ||
| 7466 | BI dihydrochloride | Jan 2022 |
| DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers | ||
| 7541 | Helianorphin-19 | Jan 2022 |
| Opioid receptor (KOR) agonist | ||
| 6955 | Ceapin A7 | Jan 2022 |
| Selective inhibitor of ATF6α; sensitizes cells to ER stress | ||
| 7206 | 5-Ethynyluridine | Jan 2022 |
| Uridine analog, used for labeling RNA synthesis | ||
| 7497 | Vandetanib | Jan 2022 |
| Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity | ||
| 7549 | BAY 1816032 | Jan 2022 |
| Potent and selective BUB1 kinase inhibitor |