New Products

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7736 Thalidomide 5'-amine-PEG2-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7735 Thalidomide 5'-amine-PEG1-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7737 Thalidomide 5'-amine-PEG3-amine Jul 2022
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7712 Semax Jun 2022
Reduces Aβ aggregation and fibrillogenesis; neuroprotective and neurotrophic peptide
7196 Indinavir sulfate Jun 2022
Potent and selective HIV-1 and HIV-2 protease inhibitor
7733 Thalidomide 5'-amine-alkylC10-amine Jun 2022
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7629 Panobinostat Jun 2022
Pan-histone deacetylase inhibitor
7510 Indocyanine green Jun 2022
Near-infrared fluorescent dye
7670 Phenyl-glutarimide 4'-oxyacetic acid Jun 2022
Functionalized cereblon ligand for PROTAC development
7701 RAGE 229 Jun 2022
ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice
7675 SJ 1008030 Jun 2022
Selective JAK2 Degrader (PROTAC®)
6923 AMZ 30 Jun 2022
Potent, selective and irreversible protein phosphatase methylesterase-1 (PME-1) inhibitor
7684 Rilpivirine May 2022
Non-nucleoside reverse transcriptase inhibitor
7635 tri-GalNAc biotin May 2022
Biotinylated ASGPR ligand for LYTAC research and development
6878 BMS 466442 May 2022
Potent and selective inhibitor of asc-1
7679 RECTAS May 2022
IKBKAP pre-mRNA splicing modulator
7588 SK 575-NEG May 2022
Negative control for SK 575 (Cat. No. 7583)
7557 Thalidomide 5'-amine-alkylC8-amine May 2022
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7723 RGD peptide May 2022
Minimal recognition sequence for integrin binding; potent integrin inhibitor
7650 AZD 2858 May 2022
Highly potent GSK-3 inhibitor; inhibits tau phosphorylation
6529 SGC AAK1 1N May 2022
Negative control for SGC AAK1 1 (Cat.No. 6528)
6604 VER 246608 May 2022
Potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 /4 inhibitor
7640 Tucatinib May 2022
Potent and selective ErbB2 inhibitor
7530 dTAG-47 May 2022
Degrades mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
7392 5-Ph-IAA May 2022
Selective and potent TAG Degrader for auxin-inducible degron 2 system
7446 SCOTfluor 510, fluoro May 2022
Amine-reactive fluorescent probe precursor
7696 Selpercatinib May 2022
Potent and selective RET inhibitor
7531 dTAG-47-NEG May 2022
Negative control for dTAG-47 (Cat. No. 7530)
7714 EDA-DA May 2022
Unnatural dipeptide building block with alkyne group for functionalizing peptidoglycan
7278 α1A-AR Degrader 9c May 2022
Selective α1A adrenergic receptor Degrader (PROTAC®)
7680 ABT 263 May 2022
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
7663 Ozanimod May 2022
Potent and selective S1P1 and S1P5 agonist
7689 (+)-JQ1 bump, acid functionalized May 2022
Functionalized BET bromodomain ligand; precursor for Tag Degraders
7583 SK 575 May 2022
Potent PARP1 Degrader (PROTAC®)
7339 RIPA 56 May 2022
Potent and metabolically stable RIP1 kinase inhibitor
7137 Cambinol May 2022
nSMase2 inhibitor
7215 VH 032 amide-PEG4-acid May 2022
VHL ligand with PEG linker and terminal acid for onward chemistry
TB6666-RMU T3 May 2022
T3 synthesized to Ancillary Material Grade
TB2939-RMU A 83-01 May 2022
A 83-01 synthesized to Ancillary Material Grade
7641 Mito-HE May 2022
Fluorescent mitochondrial superoxide indicator in live cells
7492 Lomitapide mesylate May 2022
Potent microsomal triglyceride transfer protein (MTP) inhibitor
7494 CIA 1 Apr 2022
COUP-TFII inhibitor
7652 Linsitinib Apr 2022
Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor
7659 Verubecestat Apr 2022
BACE1 and BACE2 inhibitor
7122 Thioflavin T Apr 2022
Fluorescent amyloid stain, binds to the stacked β sheets of amyloid fibrils
7553 Ac4ManNDAz Apr 2022
Photo-crosslinking probe for studying glycoproteins and glycolipids
7485 Covidcil-19 Apr 2022
Binds to SARS-CoV-2 frameshifting element and reduces frameshifting efficiency
7726 DMSO, Cell Cryopreserve Grade Apr 2022
Intracellular cryoprotective agent
7532 CSN5i-3-NEG Apr 2022
Negative control for CSN5i-3 (Cat. No. 7089)
7089 CSN5i-3 Apr 2022
Potent and selective CSN5 (COP9 signalosome) inhibitor
TB6053-GMP LDN 193189 Apr 2022
LDN 193189 synthesized to cGMP guidelines
7687 BromoTag® cis-AGB1 Apr 2022
Negative control for BromoTag® AGB1 (Cat.No. 7686)
7686 BromoTag® AGB1 Apr 2022
Potent and selective Degrader of Brd4BD2 L387A fusion proteins (BromoTag®)
7512 3-Bromopyruvate Apr 2022
MCT1 inhibitor; also inhibits hexokinase II
7590 Pexidartinib Apr 2022
Potent CSF-1R inhibitor
7376 2A3 Mar 2022
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
TB1285-RMU Staurosporine Mar 2022
Staurosporine synthesized to Ancillary Material Grade
7498 SPOP-i-6lc Mar 2022
SPOP E3 ubiquitin ligase inhibitor
7542 SJ 1008066 Mar 2022
MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction
7483 BDY FL VH032 Mar 2022
High-affinity VHL fluorescent probe for TR-FRET and FP assays
7010 EM 163 Mar 2022
TIR-TIR interaction inhibitor
7201 Phalloidin-Janelia Fluor® 646 Mar 2022
Red fluorescent F-actin probe
7667 Pimavanserin Mar 2022
Selective 5-HT2A inverse agonist
7586 Molnupiravir Mar 2022
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
7362 Phototrexate Mar 2022
Photoswitchable inhibitor of human dihydrofolate reductase
7630 Pridopidine Mar 2022
Highly selective σ1 agonist
2395 Sertraline hydrochloride Mar 2022
5-HT reuptake inhibitor
TB4439-RMU ISX 9 Mar 2022
ISX 9 synthesized to Ancillary Material Grade
7682 JQAD1 Feb 2022
Potent and selective EP300 Degrader
7488 MRTX 849 Feb 2022
Mutation-selective inhibitor of KRASG12C
7584 iP300v Feb 2022
Negative control for iP300w (Cat. No. 7270)
7589 Adavosertib Feb 2022
Potent and selective Wee1 inhibitor
7631 Idelalisib Feb 2022
Potent PI 3-Kinase δ isoform inhibitor
7018 CBR-470-1 Feb 2022
PGK1 inhibitior; activates Nrf2
7507 Evofosfamide Feb 2022
Hypoxia-activated DNA alkylating agent prodrug
7591 CB 839 Jan 2022
Potent glutaminase GLS1 inhibitor
7457 CAM 833 Jan 2022
Selective orthosteric inhibitor of the BRCA2-RAD51 interaction
7578 Tocriscreen Epigenetics 3.0 Jan 2022
A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening and chemical biology applications
7579 Olaparib Jan 2022
Potent PARP inhibitor
7466 BI dihydrochloride Jan 2022
DFHBI derivative for imaging of RNA in living cells that bind Broccoli aptamers
7541 Helianorphin-19 Jan 2022
Opioid receptor (KOR) agonist
6955 Ceapin A7 Jan 2022
Selective inhibitor of ATF6α; sensitizes cells to ER stress
7206 5-Ethynyluridine Jan 2022
Uridine analog, used for labeling RNA synthesis
7497 Vandetanib Jan 2022
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
7549 BAY 1816032 Jan 2022
Potent and selective BUB1 kinase inhibitor