New ProductsView all new products by date added
Search for new products by date added, alphabetically, or by pharmacological action.
New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the New symbol.
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| Cat. No. | Product Name / Activity | Date Added |
|---|---|---|
| 7177 | NR 7h | May 2020 |
| Potent and selective p38α and p38β degrader; active in vivo | ||
| 6807 | NNC 0640 | May 2020 |
| Negative allosteric modulator of glucagon and GLP-1 receptors | ||
| 6962 | JBJ-03-142-02 | May 2020 |
| Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors | ||
| 6650 | YADA | May 2020 |
| Green-yellow lucifer yellow-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 7233 | SBP1 | May 2020 |
| ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain | ||
| 6896 | Dynapyrazole A | May 2020 |
| Hedgehog signaling inhibitor; dynein inhibitor | ||
| 6831 | TRPV3 74a | May 2020 |
| Selective TRPV3 antagonist; brain penetrant | ||
| 6825 | SGC 3027 | May 2020 |
| Potent and selective PRMT7 inhibitor | ||
| 6838 | SGC 3027N | May 2020 |
| Negative control for SGC 3027 (Cat. No. 6825) | ||
| 6354 | CNV Dopamine | May 2020 |
| Caged dopamine; photolysed by UV light | ||
| 7004 | NAI | May 2020 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable | ||
| 6998 | SHIN 1 | May 2020 |
| Potent SHMT inhibitor | ||
| 7082 | DL 175 | Apr 2020 |
| Potent and selective GPR84 agonist | ||
| 5755 | PF 04479745 | Apr 2020 |
| Potent and selective 5-HT2C agonist | ||
| 6944 | Pomalidomide 4'-alkylC8-amine | Apr 2020 |
| Cereblon ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7117 | Chemerin-9, Mouse | Apr 2020 |
| Potent CMKLR1 agonist; c-terminal peptide of full length mouse chemerin | ||
| 7116 | Chemerin-9, Human | Apr 2020 |
| Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin | ||
| 6779 | Davunetide | Apr 2020 |
| Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo | ||
| 6892 | RIPGBM | Apr 2020 |
| RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant | ||
| 5814 | GoSlo SR 5-69 | Apr 2020 |
| BK channel activator | ||
| 6722 | NBC 19 | Apr 2020 |
| Potent NLRP3 inflammasome inhibitor | ||
| 6649 | RADA | Apr 2020 |
| Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria | ||
| 7200 | Tocriscreen FDA-Approved Drugs Library | Apr 2020 |
| Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA | ||
| 7090 | Digoxigenin-11-dUTP | Mar 2020 |
| Hapten modified dUTP for ISH | ||
| 6739 | YNT 185 | Mar 2020 |
| Potent and selective OX2 agonist | ||
| 6939 | cis-VZ 185 | Mar 2020 |
| Negative control for VZ 185 (Cat. No. 6936) | ||
| 6826 | AZ 1729 | Mar 2020 |
| FFA2 allosteric agonist; displays bias for the Gi signaling pathway | ||
| 6911 | VH 032, phenol | Mar 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 7163 | Chroman 1 | Mar 2020 |
| Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis | ||
| 7074 | VH 032 amide-alkylC7-amine | Mar 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 6670 | TP 238 | Mar 2020 |
| CECR2 and BPTF/FALZ inhibitor | ||
| 6758 | CLP 290 | Mar 2020 |
| K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242) | ||
| 6372 | PSB CB5 | Mar 2020 |
| Selective GPR18 antagonist | ||
| 6976 | JNJ 10198409 | Mar 2020 |
| Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases | ||
| 7048 | Ruxolitinib phosphate | Feb 2020 |
| Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor | ||
| 7121 | 7-Aminoactinomycin D | Feb 2020 |
| Fluorescent DNA stain | ||
| 7162 | iFSP1 | Feb 2020 |
| Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer | ||
| 7064 | Ruxolitinib | Feb 2020 |
| Potent and selective JAK1/JAK2 inhibitor; orally bioavailable | ||
| 6928 | VU 6001966 | Feb 2020 |
| Potent and selective negative allosteric modulator of mGlu2 receptors | ||
| 6833 | RO 5263397 hydrochloride | Feb 2020 |
| Potent TA1 receptor agonist | ||
| 7038 | Palonosetron hydrochloride | Feb 2020 |
| Highly potent and high affinity 5-HT3 antagonist | ||
| 6791 | BC-LI-0186 | Feb 2020 |
| Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor | ||
| 7088 | Janelia Fluor® 646, Azide | Feb 2020 |
| Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging | ||
| 7039 | SK 609 | Feb 2020 |
| Dopamine D3 receptor biased agonist | ||
| 6110 | HJC 0416 hydrochloride | Feb 2020 |
| STAT3 inhibitor | ||
| 7040 | C 176 | Feb 2020 |
| mSTING antagonist | ||
| 6993 | Janelia Fluor® 646, free acid | Feb 2020 |
| Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging | ||
| 5746 | NESS 0327 | Feb 2020 |
| Ultra-high affinity and selective CB1 antagonist | ||
| 6457 | Cyanine 3 Tyramide | Jan 2020 |
| Orange fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 7150 | Tocriscreen 2.0 Max | Jan 2020 |
| A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions) | ||
| 7015 | IA-Alkyne | Jan 2020 |
| Broad spectrum cysteine reactive probe | ||
| 6458 | Cyanine 5 Tyramide | Jan 2020 |
| Red fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6456 | Fluorescein Tyramide | Jan 2020 |
| Green fluorescent reagent widely used for signal amplification in IHC and ISH | ||
| 6398 | SKA 121 | Jan 2020 |
| Positive allosteric modulator of KCa3.1 channels | ||
| 6220 | PM 226 | Jan 2020 |
| Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective | ||
| 6858 | MMG 11 | Jan 2020 |
| TLR2 antagonist | ||
| 6925 | NBC 6 | Jan 2020 |
| NLRP3 inflammasome inhibitor | ||
| TB3748-GMP | XAV 939 | Jan 2020 |
| XAV 939 synthesized to cGMP guidelines | ||
| 7051 | Tasquinimod | Jan 2020 |
| High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic | ||
| 6985 | VH 032 amide-alkylC5-amine | Jan 2020 |
| VHL ligand with alkyl linker and terminal amine for onward chemistry | ||
| 7152 | Tocriscreen 2.0 Micro | Jan 2020 |
| A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions) | ||
| 6952 | VH 101, phenol | Jan 2020 |
| Hydroxyl functionalized VHL ligand | ||
| 7151 | Tocriscreen 2.0 Mini | Jan 2020 |
| A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions) | ||
| 6964 | LY 2119620 | Jan 2020 |
| Positive allosteric modulator of M2 and M4 receptors | ||
| 7009 | PDD 00031705 | Dec 2019 |
| Negative control for PDD 00017238 (Cat. No. 7007) | ||
| 7007 | PDD 00017238 | Dec 2019 |
| High affinity and potent PARG inhibitor | ||
| 6725 | CHDI 00390576 | Dec 2019 |
| Potent and selective class IIa HDAC inhibitor; brain penetrant | ||
| 6991 | Poly Vinyl Alcohol | Dec 2019 |
| Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion | ||
| 6586 | Targapremir 210 | Dec 2019 |
| Inhibits formation of miR-210 | ||
| 6931 | AF 64394 | Dec 2019 |
| Potent and selective GPR3 inverse agonist | ||
| 7049 | Nintedanib | Dec 2019 |
| Potent VEGFR, PDGFR and FGFR inhibitor | ||
| 7002 | KYA 1797K | Dec 2019 |
| Wnt/β-catenin signaling inhibitor | ||
| 7071 | GSK 2239633A | Dec 2019 |
| Potent CCR4 antagonist | ||
| 7026 | Veliparib dihydrochloride | Dec 2019 |
| High affinity PARP-1 and -2 inhibitor; orally bioavailable | ||
| 6860 | SB 290157 trifluoroacetate | Dec 2019 |
| Potent C3a receptor antagonist | ||
| 7050 | Ribociclib | Dec 2019 |
| Dual cdk4/cdk6 inhibitor; orally bioavailable | ||
| 6961 | FzM1.8 | Dec 2019 |
| Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness | ||
| 6912 | dTAG-7 | Dec 2019 |
| First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation | ||
| 6775 | ST 045849 | Dec 2019 |
| O-GlcNAc transferase (OGT) inhibitor | ||
| 6875 | TRPC6-PAM-C20 | Dec 2019 |
| Selective TRPC6 positive allosteric modulator | ||
| 6900 | NNMTi | Dec 2019 |
| Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation | ||
| 6981 | TL 0259 | Dec 2019 |
| Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable | ||
| 7053 | MM 07 | Dec 2019 |
| Apelin receptor biased agonist; exhibits bias for the G protein pathway | ||
| 6799 | MB 0223 | Dec 2019 |
| Dynamin-related GTPase DRP1 partial inhibitor | ||
| 6729 | TAN 452 | Dec 2019 |
| Potent and selective peripherally acting δ opioid antagonist; antianalgesic. | ||
| 5860 | 7rh | Dec 2019 |
| Potent and selective DDR1 inhibitor; orally bioavailable |