New Products

View all new products by date added

Search for new products by date added, alphabetically, or by pharmacological action.

New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules and peptides being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can. New products can be identified throughout the Tocris website by the symbol.

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Cat. No. Product Name / Activity Date Added
7177 NR 7h May 2020
Potent and selective p38α and p38β degrader; active in vivo
6807 NNC 0640 May 2020
Negative allosteric modulator of glucagon and GLP-1 receptors
6962 JBJ-03-142-02 May 2020
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
6650 YADA May 2020
Green-yellow lucifer yellow-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria
7233 SBP1 May 2020
ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
6896 Dynapyrazole A May 2020
Hedgehog signaling inhibitor; dynein inhibitor
6831 TRPV3 74a May 2020
Selective TRPV3 antagonist; brain penetrant
6825 SGC 3027 May 2020
Potent and selective PRMT7 inhibitor
6838 SGC 3027N May 2020
Negative control for SGC 3027 (Cat. No. 6825)
6354 CNV Dopamine May 2020
Caged dopamine; photolysed by UV light
7004 NAI May 2020
Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
6998 SHIN 1 May 2020
Potent SHMT inhibitor
7082 DL 175 Apr 2020
Potent and selective GPR84 agonist
5755 PF 04479745 Apr 2020
Potent and selective 5-HT2C agonist
6944 Pomalidomide 4'-alkylC8-amine Apr 2020
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7117 Chemerin-9, Mouse Apr 2020
Potent CMKLR1 agonist; c-terminal peptide of full length mouse chemerin
7116 Chemerin-9, Human Apr 2020
Potent CMKLR1 agonist; c-terminal peptide of full length human chemerin
6779 Davunetide Apr 2020
Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo
6892 RIPGBM Apr 2020
RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
5814 GoSlo SR 5-69 Apr 2020
BK channel activator
6722 NBC 19 Apr 2020
Potent NLRP3 inflammasome inhibitor
6649 RADA Apr 2020
Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria
7200 Tocriscreen FDA-Approved Drugs Library Apr 2020
Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA
7090 Digoxigenin-11-dUTP Mar 2020
Hapten modified dUTP for ISH
6739 YNT 185 Mar 2020
Potent and selective OX2 agonist
6939 cis-VZ 185 Mar 2020
Negative control for VZ 185 (Cat. No. 6936)
6826 AZ 1729 Mar 2020
FFA2 allosteric agonist; displays bias for the Gi signaling pathway
6911 VH 032, phenol Mar 2020
Hydroxyl functionalized VHL ligand
7163 Chroman 1 Mar 2020
Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogeneisis
7074 VH 032 amide-alkylC7-amine Mar 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
6670 TP 238 Mar 2020
CECR2 and BPTF/FALZ inhibitor
6758 CLP 290 Mar 2020
K+/Cl- cotransporter 2 (KCC2) activator; orally bioavailable prodrug of CLP 257 (Cat. No.5242)
6372 PSB CB5 Mar 2020
Selective GPR18 antagonist
6976 JNJ 10198409 Mar 2020
Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
7048 Ruxolitinib phosphate Feb 2020
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
7121 7-Aminoactinomycin D Feb 2020
Fluorescent DNA stain
7162 iFSP1 Feb 2020
Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer
7064 Ruxolitinib Feb 2020
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
6928 VU 6001966 Feb 2020
Potent and selective negative allosteric modulator of mGlu2 receptors
6833 RO 5263397 hydrochloride Feb 2020
Potent TA1 receptor agonist
7038 Palonosetron hydrochloride Feb 2020
Highly potent and high affinity 5-HT3 antagonist
6791 BC-LI-0186 Feb 2020
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
7088 Janelia Fluor® 646, Azide Feb 2020
Red dye (Reactive group: azide). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, and live cell imaging
7039 SK 609 Feb 2020
Dopamine D3 receptor biased agonist
6110 HJC 0416 hydrochloride Feb 2020
STAT3 inhibitor
7040 C 176 Feb 2020
mSTING antagonist
6993 Janelia Fluor® 646, free acid Feb 2020
Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging
5746 NESS 0327 Feb 2020
Ultra-high affinity and selective CB1 antagonist
6457 Cyanine 3 Tyramide Jan 2020
Orange fluorescent reagent widely used for signal amplification in IHC and ISH
7150 Tocriscreen 2.0 Max Jan 2020
A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions)
7015 IA-Alkyne Jan 2020
Broad spectrum cysteine reactive probe
6458 Cyanine 5 Tyramide Jan 2020
Red fluorescent reagent widely used for signal amplification in IHC and ISH
6456 Fluorescein Tyramide Jan 2020
Green fluorescent reagent widely used for signal amplification in IHC and ISH
6398 SKA 121 Jan 2020
Positive allosteric modulator of KCa3.1 channels
6220 PM 226 Jan 2020
Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective
6858 MMG 11 Jan 2020
TLR2 antagonist
6925 NBC 6 Jan 2020
NLRP3 inflammasome inhibitor
TB3748-GMP XAV 939 Jan 2020
XAV 939 synthesized to cGMP guidelines
7051 Tasquinimod Jan 2020
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
6985 VH 032 amide-alkylC5-amine Jan 2020
VHL ligand with alkyl linker and terminal amine for onward chemistry
7152 Tocriscreen 2.0 Micro Jan 2020
A library of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
6952 VH 101, phenol Jan 2020
Hydroxyl functionalized VHL ligand
7151 Tocriscreen 2.0 Mini Jan 2020
A library of 1280 biologically active compounds (50 μL 10 mM DMSO solutions)
6964 LY 2119620 Jan 2020
Positive allosteric modulator of M2 and M4 receptors
7009 PDD 00031705 Dec 2019
Negative control for PDD 00017238 (Cat. No. 7007)
7007 PDD 00017238 Dec 2019
High affinity and potent PARG inhibitor
6725 CHDI 00390576 Dec 2019
Potent and selective class IIa HDAC inhibitor; brain penetrant
6991 Poly Vinyl Alcohol Dec 2019
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
6586 Targapremir 210 Dec 2019
Inhibits formation of miR-210
6931 AF 64394 Dec 2019
Potent and selective GPR3 inverse agonist
7049 Nintedanib Dec 2019
Potent VEGFR, PDGFR and FGFR inhibitor
7002 KYA 1797K Dec 2019
Wnt/β-catenin signaling inhibitor
7071 GSK 2239633A Dec 2019
Potent CCR4 antagonist
7026 Veliparib dihydrochloride Dec 2019
High affinity PARP-1 and -2 inhibitor; orally bioavailable
6860 SB 290157 trifluoroacetate Dec 2019
Potent C3a receptor antagonist
7050 Ribociclib Dec 2019
Dual cdk4/cdk6 inhibitor; orally bioavailable
6961 FzM1.8 Dec 2019
Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness
6912 dTAG-7 Dec 2019
First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
6775 ST 045849 Dec 2019
O-GlcNAc transferase (OGT) inhibitor
6875 TRPC6-PAM-C20 Dec 2019
Selective TRPC6 positive allosteric modulator
6900 NNMTi Dec 2019
Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
6981 TL 0259 Dec 2019
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
7053 MM 07 Dec 2019
Apelin receptor biased agonist; exhibits bias for the G protein pathway
6799 MB 0223 Dec 2019
Dynamin-related GTPase DRP1 partial inhibitor
6729 TAN 452 Dec 2019
Potent and selective peripherally acting δ opioid antagonist; antianalgesic.
5860 7rh Dec 2019
Potent and selective DDR1 inhibitor; orally bioavailable