Cat. No. | Product Name / Activity |
---|---|
4400 | (±)-CPSI 1306 |
Reported macrophage migration inhibitory factor (MIF) inhibitor | |
4401 | SMIFH2 |
FH2 domain inhibitor; prevents actin nucleation | |
4402 | 26RFa |
Ligand of GPR103; orexigenic neuropeptide | |
4403 | Pyroxamide |
Histone deacetylase inhibitor | |
4404 | VU 0365114 |
Positive allosteric modulator of M5 receptors | |
4406 | 10058-F4 |
Inhibits c-Myc-Max dimerization | |
4407 | TC-G 1004 |
Potent and selective A2A antagonist | |
4408 | DMOG |
Prolyl hydroxylase inhibitor | |
4409 | SR 1664 |
High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation | |
4410 | Ocinaplon |
GABAA modulator; anxiolytic | |
4414 | TP 003 |
GABAA partial agonist; acts at benzodiazepine site | |
4415 | MK 0343 |
GABAA partial agonist; displays subtype selectivity | |
4416 | ADX 10059 hydrochloride |
Negative allosteric modulator of mGlu5 receptors | |
4417 | DBeQ |
Selective and reversible p97 ATPase inhibitor | |
4418 | Saquinavir mesylate |
HIV protease inhibitor | |
4419 | PF 945863 |
Macrolide antibiotic | |
4420 | Carbazeran citrate |
Aldehyde oxidase substrate; PDE inhibitor | |
4421 | LF 11 |
Antibiotic; neutralizes LPS | |
4422 | Lauryl-LF 11 |
Analog of LF 11 (Cat. No. 4421); antibiotic | |
4423 | CHIR 99021 |
Highly selective GSK-3 inhibitor; acts as Wnt activator | |
4424 | SR 16584 |
Selective α3β4 nAChR antagonist | |
4426 | Tanshinone IIA |
Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties | |
4427 | Febuxostat |
Xanthine oxidase inhibitor | |
4428 | MitoPY1 |
Fluorescent mitochondrial hydrogen peroxide indicator | |
4429 | NQDI 1 |
ASK1 inhibitor | |
4430 | BAY 41-2272 |
Soluble guanylyl cyclase (sGC) activator | |
4431 | A 1070722 |
Highly potent, selective GSK-3 inhibitor | |
4432 | TTP 22 |
High affinity, selective CK2 inhibitor | |
4433 | Pluripotin |
Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal | |
4434 | Wiskostatin |
N-WASP inhibitor; inhibits Arp2/3 activation | |
4435 | TC-N 1752 |
NaV channel blocker | |
4436 | 8-Chloroadenosine |
Cytotoxic nucleoside analog; inhibits RNA synthesis | |
4437 | VU 0357121 |
Positive allosteric modulator of mGlu5 receptors | |
4438 | MFZ 10-7 |
Negative allosteric modulator of mGlu5 receptors | |
4439 | ISX 9 |
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation | |
4440 | Rivastigmine tartrate |
Dual AChE and BChE inhibitor | |
4441 | SEN 12333 |
α7 nAChR agonist; also histamine H3 antagonist | |
4444 | Fatostatin A |
Cell permeable inhibitor of SREBP activation | |
4445 | PFI 1 |
BET bromodomain inhibitor | |
4446 | CID 5951923 |
Krüppel-like factor 5 (KLF5) inhibitor | |
4447 | Org 24598 |
Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo | |
4448 | Ceranib 1 |
Ceramidase inhibitor; antiproliferative | |
4451 | IOX 2 |
Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor | |
4452 | GGsTop |
Inhibitor of γ-glutamyl transpeptidase (GGT) | |
4453 | GDC 0879 |
Potent B-Raf inhibitor | |
4454 | Diclofenac sodium salt |
Cyclooxygenase inhibitor; NSAID | |
4455 | Captopril |
ACE inhibitor; also inhibits LTA4 hydrolase | |
4456 | Amitriptyline hydrochloride |
5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist | |
4457 | YE 120 |
GPR35 agonist | |
4458 | VU 29 |
Potent positive allosteric modulator of mGlu5 receptors | |
4459 | TC-S 7005 |
Potent and selective PLK2 inhibitor | |
4460 | Trifluorothymidine |
Thymidylate synthetase inhibitor | |
4462 | NS 3623 |
KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic | |
4463 | SR 8278 |
Rev-Erbα antagonist | |
4464 | IOX 1 |
Histone demethylase inhibitor; cell permeable | |
4465 | TCS ERK 11e |
Potent and selective ERK2 inhibitor | |
4466 | PHP 501 trifluoroacetate |
Potent GABAA antagonist | |
4468 | AT 1015 |
Long-acting 5-HT2A antagonist | |
4469 | VU 0364770 |
Positive allosteric modulator of mGlu4 receptors | |
4470 | EMD 281014 hydrochloride |
Selective 5-HT2A antagonist | |
4471 | DMH4 |
Selective VEGFR-2 inhibitor | |
4472 | BAY 60-6583 |
Potent A2B agonist; cardioprotective | |
4473 | A 804598 |
Potent and selective P2X7 antagonist | |
4474 | 20(S)-Hydroxycholesterol |
Allosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation | |
4475 | Cardionogen 1 |
Inhibitor of Wnt/β-catenin signaling | |
4477 | A 844606 |
Selective α7 nAChR partial agonist | |
4478 | GPBAR-A |
GPBA receptor (TGR5) agonist | |
4479 | 4μ8C |
Inhibits IRE1α endoribonuclease activity | |
4480 | DV 7028 hydrochloride |
Selective 5-HT2A antagonist; antithrombotic | |
4481 | Ki 20227 |
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation | |
4482 | PR 619 |
Broad spectrum DUB inhibitor | |
4483 | A 484954 |
CaM kinase III (eEF-2 kinase) inhibitor | |
4484 | STF 31 |
NAMPT inhibitor; also GLUT1 inhibitor | |
4485 | P 22077 |
USP7 inhibitor | |
4486 | PMSF |
Non-selective protease inhibitor; also blocks anandamide metabolism | |
4487 | (±)-AMG 487 |
CXCR3 antagonist; inhibits cell migration and metastasis | |
4488 | 1-Deazaadenosine |
Adenosine deaminase inhibitor | |
4489 | DBZ |
γ-secretase inhibitor; inhibits Notch pathway | |
4490 | Alantolactone |
Antiproliferative; induces activin/Smad3 signaling | |
4491 | DQP 1105 |
GluN2C/GluN2D-selective NMDA antagonist | |
4492 | Cerestat |
Potent and noncompetitive NMDA antagonist | |
4493 | Paliperidone |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic | |
4494 | (R)-DPN |
Enantiomer of DPN (Cat. No. 1494) | |
4496 | BC 11-38 |
Selective PDE11 inhibitor | |
4498 | Y 11 |
Potent and selective FAK inhibitor | |
4499 | (+)-JQ1 |
Potent and selective BET bromodomain inhibitor; cell permeable |