All ProductsDisplaying Products by Catalog Number (4400 - 4499)
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| Cat. No. | Product Name / Activity |
|---|---|
| 4400 | (±)-CPSI 1306 |
| Reported macrophage migration inhibitory factor (MIF) inhibitor | |
| 4401 | SMIFH2 |
| FH2 domain inhibitor; prevents actin nucleation | |
| 4403 | Pyroxamide |
| Histone deacetylase inhibitor | |
| 4404 | VU 0365114 |
| Positive allosteric modulator of M5 receptors | |
| 4406 | 10058-F4 |
| Inhibits c-Myc-Max dimerization | |
| 4407 | TC-G 1004 |
| Potent and selective A2A antagonist | |
| 4408 | DMOG |
| Prolyl hydroxylase inhibitor | |
| 4409 | SR 1664 |
| High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation | |
| 4410 | Ocinaplon |
| GABAA modulator; anxiolytic | |
| 4414 | TP 003 |
| GABAA partial agonist; acts at benzodiazepine site | |
| 4415 | MK 0343 |
| GABAA partial agonist; displays subtype selectivity | |
| 4416 | ADX 10059 hydrochloride |
| Negative allosteric modulator of mGlu5 receptors | |
| 4417 | DBeQ |
| Selective and reversible p97 ATPase inhibitor | |
| 4418 | Saquinavir mesylate |
| HIV protease inhibitor | |
| 4419 | PF 945863 |
| Macrolide antibiotic | |
| 4420 | Carbazeran citrate |
| Aldehyde oxidase substrate; PDE inhibitor | |
| 4423 | CHIR 99021 |
| Highly selective GSK-3 inhibitor; acts as Wnt activator | |
| 4424 | SR 16584 |
| Selective α3β4 nAChR antagonist | |
| 4426 | Tanshinone IIA |
| Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties | |
| 4427 | Febuxostat |
| Xanthine oxidase inhibitor | |
| 4428 | MitoPY1 |
| Fluorescent mitochondrial hydrogen peroxide indicator | |
| 4429 | NQDI 1 |
| ASK1 inhibitor | |
| 4430 | BAY 41-2272 |
| Soluble guanylyl cyclase (sGC) activator | |
| 4431 | A 1070722 |
| Highly potent, selective GSK-3 inhibitor | |
| 4432 | TTP 22 |
| High affinity, selective CK2 inhibitor | |
| 4434 | Wiskostatin |
| N-WASP inhibitor; inhibits Arp2/3 activation | |
| 4435 | TC-N 1752 |
| NaV channel blocker | |
| 4436 | 8-Chloroadenosine |
| Cytotoxic nucleoside analog; inhibits RNA synthesis | |
| 4437 | VU 0357121 |
| Positive allosteric modulator of mGlu5 receptors | |
| 4438 | MFZ 10-7 |
| Negative allosteric modulator of mGlu5 receptors | |
| 4439 | ISX 9 |
| Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation | |
| 4440 | Rivastigmine tartrate |
| Dual AChE and BChE inhibitor | |
| 4444 | Fatostatin A |
| Cell permeable inhibitor of SREBP activation | |
| 4445 | PFI 1 |
| BET bromodomain inhibitor | |
| 4446 | CID 5951923 |
| Krüppel-like factor 5 (KLF5) inhibitor | |
| 4447 | Org 24598 |
| Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo | |
| 4448 | Ceranib 1 |
| Ceramidase inhibitor; antiproliferative | |
| 4451 | IOX 2 |
| Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor | |
| 4452 | GGsTop |
| Inhibitor of γ-glutamyl transpeptidase (GGT) | |
| 4453 | GDC 0879 |
| Potent B-Raf inhibitor | |
| 4454 | Diclofenac sodium salt |
| Cyclooxygenase inhibitor; NSAID | |
| 4456 | Amitriptyline hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist | |
| 4457 | YE 120 |
| GPR35 agonist | |
| 4459 | TC-S 7005 |
| Potent and selective PLK2 inhibitor | |
| 4460 | Trifluorothymidine |
| Thymidylate synthetase inhibitor | |
| 4462 | NS 3623 |
| KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic | |
| 4463 | SR 8278 |
| Rev-Erbα antagonist | |
| 4464 | IOX 1 |
| Histone demethylase inhibitor; cell permeable | |
| 4465 | TCS ERK 11e |
| Potent and selective ERK2 inhibitor | |
| 4466 | PHP 501 trifluoroacetate |
| Potent GABAA antagonist | |
| 4469 | VU 0364770 |
| Positive allosteric modulator of mGlu4 receptors | |
| 4470 | EMD 281014 hydrochloride |
| Selective 5-HT2A antagonist | |
| 4472 | BAY 60-6583 |
| Potent A2B agonist; cardioprotective | |
| 4473 | A 804598 |
| Potent and selective P2X7 antagonist | |
| 4474 | 20(S)-Hydroxycholesterol |
| Allosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation | |
| 4475 | Cardionogen 1 |
| Inhibitor of Wnt/β-catenin signaling | |
| 4477 | A 844606 |
| Selective α7 nAChR partial agonist | |
| 4478 | GPBAR-A |
| GPBA receptor (TGR5) agonist | |
| 4479 | 4μ8C |
| Inhibits IRE1α endoribonuclease activity | |
| 4481 | Ki 20227 |
| c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation | |
| 4482 | PR 619 |
| Broad spectrum DUB inhibitor | |
| 4483 | A 484954 |
| CaM kinase III (eEF-2 kinase) inhibitor | |
| 4484 | STF 31 |
| NAMPT inhibitor; also GLUT1 inhibitor | |
| 4485 | P 22077 |
| USP7 inhibitor | |
| 4486 | PMSF |
| Non-selective protease inhibitor; also blocks anandamide metabolism | |
| 4487 | (±)-AMG 487 |
| CXCR3 antagonist; inhibits cell migration and metastasis | |
| 4488 | 1-Deazaadenosine |
| Adenosine deaminase inhibitor | |
| 4489 | DBZ |
| γ-secretase inhibitor; inhibits Notch pathway | |
| 4490 | Alantolactone |
| Antiproliferative; induces activin/Smad3 signaling | |
| 4491 | DQP 1105 |
| GluN2C/GluN2D-selective NMDA antagonist | |
| 4492 | Cerestat |
| Potent and noncompetitive NMDA antagonist | |
| 4493 | Paliperidone |
| 5-HT2A antagonist; also D2 antagonist; atypical antipsychotic | |
| 4494 | (R)-DPN |
| Enantiomer of DPN (Cat. No. 1494) | |
| 4496 | BC 11-38 |
| Selective PDE11 inhibitor | |
| 4498 | Y 11 |
| Potent and selective FAK inhibitor | |
| 4499 | (+)-JQ1 |
| Potent and selective BET bromodomain inhibitor; cell permeable |