All Products

Displaying Products by Catalog Number (4400 - 4499)

Cat. No. Product Name / Activity
4400 (±)-CPSI 1306
Reported macrophage migration inhibitory factor (MIF) inhibitor
4401 SMIFH2
FH2 domain inhibitor; prevents actin nucleation
4402 26RFa
Ligand of GPR103; orexigenic neuropeptide
4403 Pyroxamide
Histone deacetylase inhibitor
4404 VU 0365114
Positive allosteric modulator of M5 receptors
4406 10058-F4
Inhibits c-Myc-Max dimerization
4407 TC-G 1004
Potent and selective A2A antagonist
4408 DMOG
Prolyl hydroxylase inhibitor
4409 SR 1664
High affinity PPARγ ligand; blocks Cdk5-dependent PPARγ phosphorylation
4410 Ocinaplon
GABAA modulator; anxiolytic
4414 TP 003
GABAA partial agonist; acts at benzodiazepine site
4415 MK 0343
GABAA partial agonist; displays subtype selectivity
4416 ADX 10059 hydrochloride
Negative allosteric modulator of mGlu5 receptors
4417 DBeQ
Selective and reversible p97 ATPase inhibitor
4418 Saquinavir mesylate
HIV protease inhibitor
4419 PF 945863
Macrolide antibiotic
4420 Carbazeran citrate
Aldehyde oxidase substrate; PDE inhibitor
4421 LF 11
Antibiotic; neutralizes LPS
4422 Lauryl-LF 11
Analog of LF 11 (Cat. No. 4421); antibiotic
4423 CHIR 99021
Highly selective GSK-3 inhibitor
4424 SR 16584
Selective α3β4 nAChR antagonist
4426 Tanshinone IIA
Inhibits NF-κB and AP-1 DNA binding. Displays antioxidant properties
4427 Febuxostat
Xanthine oxidase inhibitor
4428 MitoPY1
Fluorescent mitochondrial hydrogen peroxide indicator
4429 NQDI 1
ASK1 inhibitor
4430 BAY 41-2272
Soluble guanylyl cyclase (sGC) activator
4431 A 1070722
Highly potent, selective GSK-3 inhibitor
4432 TTP 22
High affinity, selective CK2 inhibitor
4433 Pluripotin
Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
4434 Wiskostatin
N-WASP inhibitor; inhibits Arp2/3 activation
4435 TC-N 1752
NaV channel blocker
4436 8-Chloroadenosine
Cytotoxic nucleoside analog; inhibits RNA synthesis
4437 VU 0357121
Positive allosteric modulator of mGlu5 receptors
4438 MFZ 10-7
Negative allosteric modulator of mGlu5 receptors
4439 ISX 9
Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation
4440 Rivastigmine tartrate
Dual AChE and BChE inhibitor
4441 SEN 12333
α7 nAChR agonist; also histamine H3 antagonist
4444 Fatostatin A
Cell permeable inhibitor of SREBP activation
4445 PFI 1
BET bromodomain inhibitor
4446 CID 5951923
Krüppel-like factor 5 (KLF5) inhibitor
4447 Org 24598
Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo
4448 Ceranib 1
Ceramidase inhibitor; antiproliferative
4451 IOX 2
Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor
4452 GGsTop
Inhibitor of γ-glutamyl transpeptidase (GGT)
4453 GDC 0879
Potent B-Raf inhibitor
4454 Diclofenac sodium salt
Cyclooxygenase inhibitor; NSAID
4455 Captopril
ACE inhibitor; also inhibits LTA4 hydrolase
4456 Amitriptyline hydrochloride
5-HT and NA reuptake inhibitor (SNRI); also TrkA/B agonist
4457 YE 120
GPR35 agonist
4458 VU 29
Potent positive allosteric modulator of mGlu5 receptors
4459 TC-S 7005
Potent and selective PLK2 inhibitor
4460 Trifluorothymidine
Thymidylate synthetase inhibitor
4462 NS 3623
KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic
4463 SR 8278
Rev-Erbα antagonist
4464 IOX 1
Histone demethylase inhibitor; cell permeable
4465 TCS ERK 11e
Potent and selective ERK2 inhibitor
4466 PHP 501 trifluoroacetate
Potent GABAA antagonist
4468 AT 1015
Long-acting 5-HT2A antagonist
4469 VU 0364770
Positive allosteric modulator of mGlu4 receptors
4470 EMD 281014 hydrochloride
Selective 5-HT2A antagonist
4471 DMH4
Selective VEGFR-2 inhibitor
4472 BAY 60-6583
Potent A2B agonist; cardioprotective
4473 A 804598
Potent and selective P2X7 antagonist
4474 20(S)-Hydroxycholesterol
Allosteric activator of Hedgehog (Hh) signaling; induces Smo accumulation
4475 Cardionogen 1
Inhibitor of Wnt/β-catenin signaling
4477 A 844606
Selective α7 nAChR partial agonist
4478 GPBAR-A
GPBA receptor (TGR5) agonist
4479 4μ8C
Inhibits IRE1α endoribonuclease activity
4480 DV 7028 hydrochloride
Selective 5-HT2A antagonist; antithrombotic
4481 Ki 20227
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
4482 PR 619
Broad spectrum DUB inhibitor
4483 A 484954
CaM kinase III (eEF-2 kinase) inhibitor
4484 STF 31
NAMPT inhibitor; also GLUT1 inhibitor
4485 P 22077
USP7 inhibitor
4486 PMSF
Non-selective protease inhibitor; also blocks anandamide metabolism
4487 (±)-AMG 487
CXCR3 antagonist; inhibits cell migration and metastasis
4488 1-Deazaadenosine
Adenosine deaminase inhibitor
4489 DBZ
γ-secretase inhibitor; inhibits Notch pathway
4490 Alantolactone
Antiproliferative; induces activin/Smad3 signaling
4491 DQP 1105
GluN2C/GluN2D-selective NMDA antagonist
4492 Cerestat
Potent and noncompetitive NMDA antagonist
4493 Paliperidone
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
4494 (R)-DPN
Enantiomer of DPN (Cat. No. 1494)
4496 BC 11-38
Selective PDE11 inhibitor
4498 Y 11
Potent and selective FAK inhibitor
4499 (+)-JQ1
Potent and selective BET bromodomain inhibitor; cell permeable

Tocris Products Alphabetically by Name