FFA3 agonist (pEC50 = 5.74). Inhibits nicotine and serotonin induced changes in motility of isolated muscle strips from rat colon. Also suppresses serotonin-induced fecal output in rats.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 417.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.4 mL||11.98 mL||23.96 mL|
|5 mM||0.48 mL||2.4 mL||4.79 mL|
|10 mM||0.24 mL||1.2 mL||2.4 mL|
|50 mM||0.05 mL||0.24 mL||0.48 mL|
References are publications that support the products' biological activity.
Hudson et al (2014) Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands. Mol Pharmacol. 86 200 PMID: 24870406
Kaji et al (2017) Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon. Neurogastroenterol.Motil. 30 PMID: 28714277
If you know of a relevant reference for AR 420626, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: AR 420626, supplier, AR420626, free, fatty, acid, FFAR, FFA3, agonist, agonism, short, chain, SCFA, Free, Fatty, Acid, Receptors, Free, Fatty, Acid, Receptors, Tocris Bioscience
Citations for AR 420626
Citations are publications that use Tocris products.
Currently there are no citations for AR 420626. Do you know of a great paper that uses AR 420626 from Tocris? If so please let us know.
Reviews for AR 420626
There are currently no reviews for this product. Be the first to review AR 420626 and earn rewards!
Have you used AR 420626?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.