Acetylcholine chloride

Pricing Availability   Qty
Cat.No. 2809 - Acetylcholine chloride | C7H16ClNO2 | CAS No. 60-31-1
Description: Endogenous neurotransmitter
Chemical Name: 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
Datasheet
Citations (3)
Reviews (2)
Literature

Biological Activity

Endogenous neurotransmitter. Acts at nicotinic and muscarinic acetylcholine receptors.

Technical Data

M. Wt 181.66
Formula C7H16ClNO2
Storage Desiccate at RT
CAS Number 60-31-1
PubChem ID 6060
InChI Key JUGOREOARAHOCO-UHFFFAOYSA-M
Smiles CC(OCC[N+](C)(C)C)=O.[Cl-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 18.17 100
DMSO 18.17 100

Preparing Stock Solutions

The following data is based on the product molecular weight 181.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.5 mL 27.52 mL 55.05 mL
5 mM 1.1 mL 5.5 mL 11.01 mL
10 mM 0.55 mL 2.75 mL 5.5 mL
50 mM 0.11 mL 0.55 mL 1.1 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Wessler et al (1999) The cholinergic 'pitfall': acetylcholine, a universal cell molecule in biological systems, including humans. Clin.Exp.Pharmacol.Physiol. 26 198 PMID: 10081614


If you know of a relevant reference for Acetylcholine chloride, please let us know.

View Related Products by Product Action

View all Nicotinic Receptor (Non-selective) Agonists

Keywords: Acetylcholine chloride, Acetylcholine chloride supplier, Endogenous, neurotransmitter, Acetylcholine, Nicotinic, Receptors, Non-Selective, Subtypes, nAChR, Muscarinic, (Non-selective), Non-selective, Muscarinics, 2809, Tocris Bioscience

3 Citations for Acetylcholine chloride

Citations are publications that use Tocris products. Selected citations for Acetylcholine chloride include:

Halum et al (2014) Stem cell-derived tissue-engineered constructs for hemilaryngeal reconstruction. Ann Otol Rhinol Laryngol 123 124 PMID: 24574468

Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114

Fairless et al (2013) Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS One 8 e58260 PMID: 23516458


Do you know of a great paper that uses Acetylcholine chloride from Tocris? Please let us know.

Reviews for Acetylcholine chloride

Average Rating: 5 (Based on 2 Reviews.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Acetylcholine chloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Acetylcholine chloride induces aortic ring relaxation
By Chintan Koyani on 10/22/2018
Assay Type: In Vivo
Species: Mouse
Cell Line/Tissue: Aortic ring

C57BL6 mice were administered with LPS (5 mg/kg) alone or in combination with Empagliflozin (1 µM) for 16 h. Afterwards mice were sacrificed and aortic rings were isolated. Norepinephrine pre-contracted rings were incubated with indicated (in Image) concentrations of Acetylcholine chloride (ACh) to follow endothelial relaxation.

review image

Quantification of acetylcholine in tissue by LC-MS/MS.
By Olga Malysheva on 01/04/2018
Assay Type: In Vitro
Species: Mouse

We used it as an analytical standard for quantification of acetylcholine in brain tissue.

Even 10mM solution does degrades in the -80C freezer. We keep our stock as 100mM and make new every 6 months.


Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Nicotinic ACh Receptors

Nicotinic ACh Receptors Scientific Review

Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.

Pain

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.