Unnatural amino acid. Incorporated into proteins during de novo protein synthesis, with no effect on protein degradation. Requires methionine-free medium for efficient incorporation. Substrate for wild-type methionyl-tRNA synthetase (MetRS) in vivo. Can be used in BONCAT (bio-orthogonal non-canonical amino acid tagging) for the identification of newly synthesized proteins.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 180.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.54 mL||27.69 mL||55.37 mL|
|5 mM||1.11 mL||5.54 mL||11.07 mL|
|10 mM||0.55 mL||2.77 mL||5.54 mL|
|50 mM||0.11 mL||0.55 mL||1.11 mL|
References are publications that support the biological activity of the product.
Dieterich et al (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc.Natl.Acad.Sci.U.S.A. 103 9482 PMID: 16769897
Lang & Chin et al (2014) Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins. Chem.Rev. 114 4764 PMID: 24655057
Wang et al (2017) Nonradioactive quantification of autophagic protein degradation with L-azidohomoalanine labeling. Nat.Protoc. 12 279 PMID: 28079880
If you know of a relevant reference for L-Azidohomoalanine hydrochloride, please let us know.
Keywords: L-Azidohomoalanine hydrochloride, L-Azidohomoalanine hydrochloride supplier, unnatural, amino, acid, BONCAT, protein, synthesis, bio-othogonal, non-canonical, tagging, labeling, de, novo, UAA, MetRS, methionyl-tRNA, synthetase, Amino, Acids, Biochemicals, and, Molecular, Biology, 6584, Tocris Bioscience
Citations for L-Azidohomoalanine hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for L-Azidohomoalanine hydrochloride. Do you know of a great paper that uses L-Azidohomoalanine hydrochloride from Tocris? Please let us know.
Reviews for L-Azidohomoalanine hydrochloride
There are currently no reviews for this product. Be the first to review L-Azidohomoalanine hydrochloride and earn rewards!
Have you used L-Azidohomoalanine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Spring/Summer 2018)
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Cell Metabolism
- Fluorescent Imaging
- Signal Transduction
- Stem Cells