A 410099.1 amide-PEG5-amine

Pricing Availability   Qty
Cat.No. 7221 - A 410099.1 amide-PEG5-amine | C44H72N6O11 | CAS No. 2446474-11-7
Description: IAP ligand with PEG linker and terminal amine for onward chemistry
Chemical Name: tert-Butyl ((S)-1-(((S)-2-((2S,4S)-4-(17-amino-3,6,9,12,15-pentaoxaheptadecanamido)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
Purity: ≥95% (HPLC)

Biological Activity

Functionalized IAP ligand for PROTAC® research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M. Wt 861.09
Formula C44H72N6O11
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 2446474-11-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.


References are publications that support the biological activity of the product.

Tinworth et al (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chem.Biol. 14 342 PMID: 30807093

If you know of a relevant reference for A 410099.1 amide-PEG5-amine, please let us know.

Keywords: A 410099.1 amide-PEG5-amine, A 410099.1 amide-PEG5-amine supplier, A410099.1, -, amide-PEG5-amine, PROTACs, components, IAP, PEG5, linker, amine, conjugate, building, blocks, ligands, targeted, protein, degradation, TPD, degraders, inhibitor, of, apoptosis, E3, ligase, Ligands, Plus, Linkers, 7221, Tocris Bioscience

Citations for A 410099.1 amide-PEG5-amine

Citations are publications that use Tocris products.

Currently there are no citations for A 410099.1 amide-PEG5-amine. Do you know of a great paper that uses A 410099.1 amide-PEG5-amine from Tocris? Please let us know.

Reviews for A 410099.1 amide-PEG5-amine

There are currently no reviews for this product. Be the first to review A 410099.1 amide-PEG5-amine and earn rewards!

Have you used A 410099.1 amide-PEG5-amine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review