Amyloid β-peptide (25-35) (human)

Pricing Availability Delivery Time Qty
Cat.No. 1429 - Amyloid b-peptide (25-35) (human) | Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met | CAS No. 131602-53-4
Description: Human amyloid β-protein fragment functionally required for neurotoxicity
Citations (1)

Biological Activity

Fragment of human amyloid β-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.

Technical Data

M. Wt 1060.27
Formula C45H81N13O14S
Storage Desiccate at -20°C
CAS Number 131602-53-4
PubChem ID 10843733
Smiles [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 0.50 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1060.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.94 mL 4.72 mL 9.43 mL
5 mM 0.19 mL 0.94 mL 1.89 mL
10 mM 0.09 mL 0.47 mL 0.94 mL
50 mM 0.02 mL 0.09 mL 0.19 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:
Safety Datasheet


References are publications that support the biological activity of the product.

Rush et al (1992) Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol.Aging 13 591 PMID: 1281289

Schenk et al (1995) Therapeutic approaches related to amyloid-β peptide and Alzheimer's Disease J.Med.Chem. 38 4141 PMID: 7473539

Yankner et al (1990) Neurotrophic and neurotoxic effects of amyoid β protein: reversal by tachykinin neuropeptides. Science 250 279 PMID: 2218531

If you know of a relevant reference for Amyloid β-peptide (25-35) (human), please let us know.

View Related Products by Target

Keywords: Amyloid b-peptide (25-35) (human), Amyloid b-peptide (25-35) (human) supplier, Human, amyloid, β-protein, beta-protein, fragment, functionally, neurotoxicity, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, Peptides, Amyloid, β-peptide, beta-peptide, (25-35), (human), amyloidbeta, amyloidb, Beta, 1429, Tocris Bioscience

1 Citation for Amyloid β-peptide (25-35) (human)

Citations are publications that use Tocris products. Selected citations for Amyloid β-peptide (25-35) (human) include:

Ostrovskaya et al (2014) Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J.Biomed.Sci. 21 74 PMID: 25096780

Do you know of a great paper that uses Amyloid β-peptide (25-35) (human) from Tocris? Please let us know.

Reviews for Amyloid β-peptide (25-35) (human)

There are currently no reviews for this product. Be the first to review Amyloid β-peptide (25-35) (human) and earn rewards!

Have you used Amyloid β-peptide (25-35) (human)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Neurodegeneration Product Guide

A collection of over 275 products for neurodegeneration research, the guide includes research tools for the study of:

  • Alzheimer's disease
  • Parkinson's disease
  • Huntington's disease

Alzheimer's Poster

Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.