Amyloid β-peptide (25-35) (human)
Fragment of human amyloid β-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 0.50 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1060.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.94 mL||4.72 mL||9.43 mL|
|5 mM||0.19 mL||0.94 mL||1.89 mL|
|10 mM||0.09 mL||0.47 mL||0.94 mL|
|50 mM||0.02 mL||0.09 mL||0.19 mL|
References are publications that support the biological activity of the product.
Rush et al (1992) Intracerebral β-amyloid(25-35) produces tissue damage: is it neurotoxic? Neurobiol.Aging 13 591 PMID: 1281289
Schenk et al (1995) Therapeutic approaches related to amyloid-β peptide and Alzheimer's Disease J.Med.Chem. 38 4141 PMID: 7473539
Yankner et al (1990) Neurotrophic and neurotoxic effects of amyoid β protein: reversal by tachykinin neuropeptides. Science 250 279 PMID: 2218531
If you know of a relevant reference for Amyloid β-peptide (25-35) (human), please let us know.
View Related Products by Target
Keywords: Amyloid b-peptide (25-35) (human), Amyloid b-peptide (25-35) (human) supplier, Human, amyloid, β-protein, beta-protein, fragment, functionally, neurotoxicity, β-Amyloid, beta-Amyloid, b-amyloid, Precursor, Protein, APP, Secretase, Peptides, Amyloid, β-peptide, beta-peptide, (25-35), (human), amyloidbeta, amyloidb, Beta, 1429, Tocris Bioscience
1 Citation for Amyloid β-peptide (25-35) (human)
Citations are publications that use Tocris products. Selected citations for Amyloid β-peptide (25-35) (human) include:
Ostrovskaya et al (2014) Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J.Biomed.Sci. 21 74 PMID: 25096780
Do you know of a great paper that uses Amyloid β-peptide (25-35) (human) from Tocris? Please let us know.
Reviews for Amyloid β-peptide (25-35) (human)
There are currently no reviews for this product. Be the first to review Amyloid β-peptide (25-35) (human) and earn rewards!
Have you used Amyloid β-peptide (25-35) (human)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.