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AZ PFKFB3 67
Biological Activity for AZ PFKFB3 67
AZ PFKFB3 67 is a potent and selective PFKFB3 inhibitor (IC50 values are 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively).
Compound Libraries for AZ PFKFB3 67
Technical Data for AZ PFKFB3 67
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for AZ PFKFB3 67
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for AZ PFKFB3 67
The following data is based on the product molecular weight 455.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.2 mL||10.98 mL||21.95 mL|
|5 mM||0.44 mL||2.2 mL||4.39 mL|
|10 mM||0.22 mL||1.1 mL||2.2 mL|
|50 mM||0.04 mL||0.22 mL||0.44 mL|
References for AZ PFKFB3 67
References are publications that support the biological activity of the product.
Boyd et al (2015) Structure-based design of potent and selective inhibitors of the metabolic kinase PFKFB3. J.Med.Chem. 58 3611 PMID: 25849762
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Keywords: AZ PFKFB3 67, AZ PFKFB3 67 supplier, AZPFKFB367, PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, inhibitors, inhibits, glycolysis, 5742, Tocris Bioscience
1 Citation for AZ PFKFB3 67
Citations are publications that use Tocris products. Selected citations for AZ PFKFB3 67 include:
Zheng et al (2017) LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. EMBO J 36 3325 PMID: 28963395
Do you know of a great paper that uses AZ PFKFB3 67 from Tocris? Please let us know.
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