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Displaying Products Alphabetically by Name (T)

Cat. No. Product Name / Activity
2373 T 0901317
Potent liver X receptor (LXR) agonist; also CAR inverse agonist
7690 T 112
Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes
6106 T 3364366
Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable
7317 T 5224
Selective inhibitor of c-Fos/activator protein (AP)-1
2301 T 0070907
Highly potent and selective covalent PPARγ antagonist
6666 T3
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
7570 T3 CLK
Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B
TB6666-RMU T3
T3 synthesized to Ancillary Material Grade
7054 T4
Modulator of alternative polyadenylation; inhibits rod photoreceptor gene expression via Nr2e3
8825 TAC
TERT activator
3599 TAK 165
Potent and selective ErbB2 inhibitor
5209 TAK 21d
Potent FAAH inhibitor
6587 TAK 242
TLR4 signaling inhibitor
6777 TAK 375
Very high affinity and selective melatonin receptor agonist
4254 TAK 715
Potent p38 MAPK inhibitor; anti-inflammatory
4340 TAK 779
Potent and selective CCR5 and CCR2 chemokine receptor antagonist
5403 TAK 960 hydrochloride
Potent and selective PLK1 inhibitor
5523 TAPI 0
ADAM-17 (TACE) and MMP inhibitor
6162 TAPI 1
ADAM-17 (TACE) and MMP inhibitor
6013 TAPI 2
ADAM-17 (TACE) and MMP inhibitor
6498 TASP 0277308
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
5729 TASP 0390325
Potent and selective V1B receptor antagonist; orally bioavailable
5362 TASP 0433864
Selective positive allosteric modulator of mGlu2 receptors
6227 TAT-Gap19
Cx43 hemichannel blocker
7402 TAT-Gap19(I130A)
Control peptide for TAT-Gap19
7832 TAT-PDHPS1
YAP inhibitor
7962 TAT-SAMβA Peptide
Selective antagonist of Mfn1-βIIPKC association
2905 TB 21007
α5-selective GABAA inverse agonist
2275 TBB
Selective cell-permeable CK2 inhibitor
7660 TBI
Fluorogenic ligand for Broccoli RNA aptamer
7259 TBK1 PROTAC® 3i
Potent TANK-binding kinase 1 (TBK1) PROTAC®
7260 TBK1 control PROTAC® 4
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)
1223 DL-TBOA
Selective non-transportable inhibitor of EAATs
7862 TBTA
Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction
4300 TC 14012
CXCR4 antagonist; ACKR3 (CXCR7) agonist
2737 TC 2559 difumarate
Selective α4β2 nAChR partial agonist
5412 TC AQP1 1
Aquaporin 1 (AQP1) channel blocker
4825 TC ASK 10
Potent and selective ASK1 inhibitor; orally bioavailable
6125 TC JL 37
Potent TYK2 inhibitor
4708 TC LPA5 4
LPA5 receptor antagonist
5087 TC NTR1 17
Selective NTS1 partial agonist
4625 TC OT 39
Potent non-peptide oxytocin receptor partial agonist; also V1a receptor antagonist
6884 TC SL C5
Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
4066 TC-A 2317 hydrochloride
Potent, selective Aurora kinase A inhibitor
4301 TC-DAPK 6
Potent and selective inhibitor of DAPK1
5089 TC-E 5002
Selective KDM2/7 inhibitor
4355 TC-F 2
Potent, reversible and selective FAAH inhibitor
4624 TC-FPR 43
Potent FPR2 agonist
4879 TC-G 1001
GPR35 agonist; more potent than zaprinast (Cat. No. 0947)
4407 TC-G 1004
Potent and selective A2A antagonist
5129 TC-G 1005
Potent and selective GPBA receptor (TGR5) agonist
5355 TC-G 1008
Potent and selective GPR39 agonist
4353 TC-G 24
Potent and selective GSK-3β inhibitor
4527 TC-I 15
Potent α2β1 inhibitor; displays antithrombotic activity in vivo
4632 TC-I 2000
TRPM8 blocker
5410 TC-I 2014
Potent TRPM8 antagonist
4365 TC-MCH 7c
Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist
4435 TC-N 1752
NaV channel blocker
4961 TC-S 7001
Potent and highly selective ROCK inhibitor; orally active
3567 TC-S 7003
Potent Lck inhibitor
5088 TC-S 7004
Potent and selective DYRK1A/B inhibitor
4459 TC-S 7005
Potent and selective PLK2 inhibitor
5240 TC-S 7006
Potent and selective Tpl2 (Cot; MAP3K8) inhibitor
5243 TC-S 7009
High affinity and selective HIF-2α inhibitor
2592 TCB-2
High affinity and potent 5-HT2A agonist
7489 TCH-165
Enhancer of 20S proteasome assembly and 20S-mediated protein degradation
4154 TCN 201
GluN1/GluN2A-selective NMDA antagonist
3818 TCS 1102
Potent, dual orexin receptor antagonist
3869 TCS 2002
Potent GSK-3β inhibitor
3900 TCS 2314
α4β1 (VLA-4) antagonist
4069 TCS 2510
Selective EP4 agonist
2591 TCS 359
Potent FLT3 inhibitor
4465 TCS ERK 11e
Potent and selective ERK2 inhibitor
2827 TCS JNK 5a
Selective inhibitor of JNK2 and JNK3
3222 TCS JNK 6o
Selective JNK inhibitor
TB3222-RMU TCS JNK 6o
TCS JNK 6o synthesized to Ancillary Material Grade
3371 TCS OX2 29
Potent and selective OX2 antagonist
2979 TCS PIM-1 1
Selective, ATP-competitive Pim-1 kinase inhibitor
8036 TDI 11861
Soluble adenylyl cyclase inhibitor
6092 TDZD 8
Selective non-ATP competitive inhibitor of GSK 3β
7809 TEPP 46
Potent and selective pyruvate kinase M2 (PKM2) allosteric activator
2532 TFB-TBOA
Potent and selective EAAT1 and EAAT2 blocker
5108 TFC 007
Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
1464 TFLLR-NH2
PAR1-activating peptide
3813 TFM-4AS-1
Selective androgen receptor modulator (SARM)
7742 TFRGAP-NH2
PAR3 peptide agonist
4336 TG 003
Potent inhibitor of Clk-family kinases; also inhibits DYRK1A/B
5425 TGN 020
Aquaporin 4 (AQP4) channel blocker
7778 TH 10785
OGG1 activator
7422 TH 1760
Potent and selective NUDT15 hydrolase inhibitor
6534 TH 5427 hydrochloride
Potent NUDT5 inhibitor
7719 TH 9619 disodium salt
MTHFD2 inhibitor
6532 THAL SNS 032
Potent and selective Cdk9 Degrader (PROTAC®)
1990 (R,R)-THC
Potent subtype-selective ligand; ERα agonist/ERβ antagonist
6334 THDOC
Positive modulator of GABAA receptors; endogenous neurosteroid
0807 THIP hydrochloride
GABAA agonist
3032 THIQ
Potent and selective MC4 receptor agonist
7863 THPTA
Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
6981 TL 0259
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
6524 TL 12-186
Multikinase Degrader (PROTAC®)
6746 TL 13-110
Negative control for TL 13-112 (Cat. No. 6745)
6745 TL 13-112
Selective ALK Degrader (PROTAC®)
6744 TL 13-12
Selective ALK Degrader (PROTAC®)
6747 TL 13-22
Negative control for TL 13-12 (Cat. No. 6744)
6525 TL 13-27
Negative control for TL 12-186 (Cat. No. 6524)
5910 TL4-12
Potent MAP4K2 (GCK) inhibitor
3051 TLQP 21
VGF-derived peptide
7131 TM 38837
Highly potent CB1 inverse agonist; peripherally restricted
5769 TM 5275 sodium salt
Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable
6194 TM 5441
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
7917 TM2 TEAD inhibitor
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
5960 TMI 1
Adam 17 (TACE) and MMP inhibitor; orally bioavailable
4253 TMPyP4 tosylate
Inhibitor of human telomerase
6802 6 TMR Tre
Fluorescent trehalose; selectively labels mycobacterial cell envelope
2464 TNP-ATP triethylammonium salt
Potent and selective P2X antagonist
4414 TP 003
GABAA partial agonist; acts at benzodiazepine site
6008 TP 064
Potent and selective PRMT 4 inhibitor
6670 TP 238
CECR2 and BPTF/FALZ inhibitor
6000 TP 472
Potent BRD9/7 inhibitor
5999 TP 472N
Negative control for TP 472
7771 TP-040
Potent and selective O-GlcNAcase (OGA) inhibitor
2559 TPCA-1
Potent, selective inhibitor of IKKβ
4309 TPEN
Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28
1040 TPMPA
Selective GABAA-ρ antagonist
5343 TPPB
High affinity PKC activator; also APP modulator
6908 TR 14035
Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable
8121 TRAM 1
Chemical inducer of proximity for dTAG protein FKBPF36V and ecDHFR tags
2946 TRAM 34
Potent and highly selective KCa3.1 (IK) channel blocker
3497 TRAP-6
PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist
3163 TRIS base
Commonly used laboratory reagent; used to make TBS, TAE and TBE buffers
2906 TRO 19622
Binds voltage-dependent anion channel (VDAC)
6875 TRPC6-PAM-C20
Selective positive allosteric modulator (PAM) of TRPC6
6831 TRPV3 74a
Selective TRPV3 antagonist; brain penetrant
7523 TSA Vivid™ Fluorophore Kit 520
Signal amplification kit for use in ISH, ICC and IHC
7526 TSA Vivid™ Fluorophore Kit 570
Signal amplification kit for use in ISH, ICC and IHC
7527 TSA Vivid™ Fluorophore Kit 650
Signal amplification kit for use in ISH, ICC and IHC
0761 TTNPB
Retinoic acid analog; RAR agonist
4432 TTP 22
High affinity, selective CK2 inhibitor
4601 TUG 891
Potent and selective FFA4 (GPR120) agonist
7405 TWS 119
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
5328 TY 52156
S1P3 receptor antagonist
2308 Tabimorelin hemifumarate
Potent, orally active ghrelin receptor agonist
6311 Tadalafil
Potent and highly selective PDE5 inhibitor; orally bioavailable
6430 Takinib
Potent and selective TAK1/MAP3K7 kinase inhibitor
3719 Talabostat mesylate
Potent DPP IV inhibitor; activates NLRP1b inflammasome
5032 Talampanel
Non-competitive non-NMDA iGluR antagonist
6342 Tamoxifen
Estrogen receptor partial agonist/antagonist
0999 Tamoxifen citrate
Estrogen receptor partial agonist/antagonist
3050 Tamsulosin hydrochloride
Selective α1A antagonist
2854 Tandospirone hydrochloride
Selective 5-HT1A partial agonist
5757 Tariquidar dihydrochloride
Potent P-glycoprotein (P-gp) inhibitor
7493 Tasimelteon
Selective dual melatonin receptor (MT1/MT2) agonist
7051 Tasquinimod
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
1097 Taxol
Promotes assembly and inhibits disassembly of microtubules
7315 Taxol Janelia Fluor® 526
Green-fluorescent taxol derivative; binds microtubules. Used for: microtubules imaging. Application: confocal microscopy, super resolution microscopy. Suitable for live cell imaging
6267 Taxol Janelia Fluor® 549
Yellow-fluorescent taxol derivative. Used for: microtubule staining. Application: flow cytometry, confocal microscopy, super resolution microscopy
6266 Taxol Janelia Fluor® 646
Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available
8093 Tazemetostat
Potent and selective EZH2 inhibitor
1122 Telenzepine dihydrochloride
Potent, selective M1 antagonist
2706 Temozolomide
DNA-methylating antitumor agent
3082 Tempol
Superoxide scavenger; antioxidant
5264 Temsirolimus
mTOR inhibitor; antitumor
6975 Teniposide
DNA topoisomerase II inhibitor; viral transduction enhancer
3666 Tenofovir
Reverse transcriptase inhibitor
1506 Terazosin hydrochloride
α1 antagonist; PGK1 activator
6484 Terbinafine hydrochloride
Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase
3948 Terfenadine
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
5069 Teriflunomide
Inhibitor of DHODH; active metabolite of Leflunomide
1316 Tertiapin-Q
Selective blocker of inward-rectifier K+ channels
3965 Tesaglitazar
PPARα/γ agonist
2175 Tetrabenazine
Potent inhibitor of vesicular monoamine transport
3068 Tetraethylammonium chloride
Non-selective K+ channel blocker
0312 (RS)-(Tetrazol-5-yl)glycine
Highly potent NMDA agonist
1078 Tetrodotoxin
Na+ channel blocker
1069 Tetrodotoxin citrate
Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078)
0652 Thalidomide
Binds cereblon; also TNF-α synthesis inhibitor
7518 Thalidomide 4'-ether-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6686 Thalidomide 4'-ether-PEG2-alkyne
Cereblon ligand with PEG linker and terminal alkyne for onward chemistry
7519 Thalidomide 4'-ether-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6950 Thalidomide 4'-ether-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7520 Thalidomide 4'-ether-PEG3-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6951 Thalidomide 4'-ether-PEG5-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7329 Thalidomide 4'-ether-alkylC2-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6850 Thalidomide 4'-ether-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7330 Thalidomide 4'-ether-alkylC3-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7521 Thalidomide 4'-ether-alkylC3-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7331 Thalidomide 4'-ether-alkylC4-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6917 Thalidomide 4'-ether-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7332 Thalidomide 4'-ether-alkylC5-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7522 Thalidomide 4'-ether-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7333 Thalidomide 4'-ether-alkylC6-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6627 Thalidomide 4'-ether-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7829 Thalidomide 4'-ether-alkylC6-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7334 Thalidomide 4'-ether-alkylC7-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7335 Thalidomide 4'-ether-alkylC8-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7403 Thalidomide 4'-ether-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6966 Thalidomide 4'-oxyacetamide-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6967 Thalidomide 4'-oxyacetamide-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6467 Thalidomide 4'-oxyacetamide-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6913 Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine
Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry
6949 Thalidomide 4'-oxyacetamide-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6300 Thalidomide 4'-oxyacetamide-alkylC4-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
6968 Thalidomide 4'-oxyacetamide-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6946 Thalidomide 4'-oxyacetamide-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7735 Thalidomide 5'-amine-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7736 Thalidomide 5'-amine-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7737 Thalidomide 5'-amine-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7733 Thalidomide 5'-amine-alkylC10-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7988 Thalidomide 5'-amine-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7557 Thalidomide 5'-amine-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7456 Thalidomide, 5'-fluoro
Fluoro functionalized Thalidomide; cereblon ligand for PROTACs
6685 Thalidomide, propargyl
Alkyne-functionalized Thalidomide; 'click' cereblon ligand for PROTACs
6466 Thalidomide-4-hydroxyacetate
Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
7288 Thalidomide-Cyanine 5
High affinity cereblon fluorescent probe
1138 Thapsigargin
Potent inhibitor of SERCA ATPase
4390 Thiamet G
Potent O-GlcNAcase inhibitor
3845 Thiazovivin
ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs
3280 2-ThioUTP tetrasodium salt
Potent and selective P2Y2 agonist
7122 Thioflavin T
Cell-permeable fluorescent amyloid stain. Used for: in vitro Aβ staining in brain tissues.
0644 Thioperamide
H3 antagonist; also H4 inverse agonist
3070 Thioridazine hydrochloride
Dopamine receptor antagonist; antipsychotic
7005 4-Thiouridine
Photoreactive uridine analog for RNA sequencing
1185 Thrombin Receptor Agonist Peptide
Causes platelet aggregation and secretion
4256 Tiagabine hydrochloride
Selective GAT-1 inhibitor; anticonvulsant
5579 Tilfrinib
Potent and selective breast tumor kinase (Brk) inhibitor
0826 Tiotidine
Potent and selective H2 antagonist
5902 Tiotropium bromide
Potent muscarinic receptor antagonist
5565 Tiplaxtinin
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
7389 Tissue Clearing Pro
Tissue clearing reagent kit
7563 Tissue Clearing Pro Reagent 1
Tissue clearing reagent
7390 Tissue Clearing Pro-Organoid
3D cell culture clearing reagent kit
3609 Tizanidine hydrochloride
α2 agonist
2540 Tocrifluor T1117
Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)
7152 Tocriscreen 2.0 Micro
Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
8100 Tocriscreen GPCR Compound Library
A bioactive compound library of 240 GPCR compounds (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development
7340 Tocriscreen Stem Cell Library
A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling
6555 TokeOni
NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant
5864 Tolcapone
COMT inhibitor; also inhibits transthyretin aggregation
5181 Tolvaptan
Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active
2011 Tomoxetine hydrochloride
Potent and selective noradrenalin re-uptake inhibitor
3620 Topiramate
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
4247 Torin 1
Potent and selective mTOR inhibitor
4248 Torin 2
Potent and selective mTOR inhibitor
5270 Toyocamycin
Adenosine analog; antifungal antibiotic
7709 Trametinib
Potent and selective MEK inhibitor; orally bioavailable
1098 Tranilast
Antiallergic; inhibits inflammatory mediator release from mast cells
8829 TransMoDE 3 Biotin
Biotinylated angiopep-2, induces internalization and degradation of streptavidin in brain cell lines
3852 Tranylcypromine hydrochloride
Irreversible inhibitor of LSD1; also inhibits MAO
5349 Treprostinil
Potent prostacyclin (PGI2) analog
2337 Trequinsin hydrochloride
Highly potent PDE3 inhibitor
2472 Triacsin C
Inhibitor of acyl-CoA synthetase
1406 Trichostatin A
Potent histone deacetylase inhibitor
7814 Tricyclic cytosine tC
Fluorescent tricyclic cytosine analog for RNA imaging
3253 Triptolide
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
2191 S-Trityl-L-cysteine
Potent, selective inhibitor of mitotic kinesin Eg5
7937 Trofinetide
IGF-1 synthetic analogue
3114 Troglitazone
Selective PPARγ agonist; antidiabetic agent
6002 Trolox
Antifade reagent; antioxidant vitamin E derivative; cell permeable and water soluble
2459 Tropisetron hydrochloride
Potent 5-HT3 antagonist; also α7 nAChR partial agonist
3863 Trovafloxacin mesylate
Antibiotic; inhibits bacterial DNA synthesis
3402 Tubacin
HDAC6 inhibitor; inhibits α-tubulin deacetylation
2820 (+)-Tubocurarine chloride
nAChR antagonist
7640 Tucatinib
Potent and selective ErbB2 inhibitor
3516 Tunicamycin
Antibiotic; GlcNAc phosphotransferase inhibitor

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