| Cat. No. |
Product Name / Activity |
| 6530 |
R 121919 hydrochloride |
| High affinity CRF1 antagonist; orally bioavailable |
| 4964 |
R 1485 dihydrochloride |
| Selective and high affinity 5-HT6 antagonist |
| 4885 |
R 1530 |
| Multi-RTK inhibitor; inhibits angiogenesis |
| 5288 |
R 268712 |
| Potent and selective inhibitor of TGF-βRI |
| 5494 |
R 547 |
| Potent and selective cdk inhibitor; orally bioavailable |
| 3815 |
R 568 hydrochloride |
| Positive allosteric modulator of human calcium-sensing receptor (CaSR) |
| 2194 |
R 59-022 |
| Diacylglycerol kinase inhibitor; increases PKC activity |
| 5432 |
R 7050 |
| Inhibitor of TNF-α receptor 1 signaling |
| 3407 |
R 715 |
| Potent and selective B1 antagonist |
| 3226 |
R 892 |
| Potent and selective B1 antagonist |
| 1742 |
R-96544 hydrochloride |
| Potent, selective 5-HT2A antagonist |
| 6048 |
R-BC154 |
| High affinity fluorescent a4 beta 1/a9 beta 1 inhibitor; mobilizes HSCs |
| 6054 |
R162 |
| Glutamate dehydrogenase (GDH1) inhibitor |
| 2144 |
R18 |
| Inhibitor of 14.3.3 proteins |
| 1577 |
L-R4W2 |
| TRPV1 antagonist peptide |
| 4592 |
R8-T198wt |
| Pim-1 kinase inhibitor |
| 5707 |
RA 839 |
| Nrf2 activator; inhibits Nrf2/Keap1 interaction |
| 6649 |
RADA New |
| Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria |
| 6015 |
RAF 265 |
| Raf kinase and VEGFR-2 inhibitor |
| 6259 |
RAGE antagonist peptide |
| RAGE antagonist |
| 5411 |
RBC8 |
| RalA and RalB inhibitor |
| 3139 |
RC 160 |
| sst analog |
| 7066 |
RCGD 423 |
| gp130 modulator; activates JAK/STAT signaling |
| 6845 |
RCM 1 |
| FOXM1 inhibitor |
| 3841 |
RETF-4NA |
| Selective chymase substrate |
| 3214 |
RETRA hydrochloride |
| Antitumor agent; suppresses mutant p53-bearing cancer cells |
| 3672 |
RF 9 |
| Selective NPFF1 and NPFF2 antagonist |
| 4683 |
RFRP 3 (human) |
| NPFF1 agonist; GnIH homolog |
| 5677 |
RFRP-1 (human) |
| Potent NPFF receptor agonist |
| 5761 |
RG 102240 |
| Gene switch ligand for use in inducible gene expression systems |
| 3295 |
RG 108 |
| Non-nucleoside DNA methyltransferase inhibitor |
| 3498 |
RGDS peptide |
| Integrin binding sequence; inhibits integrin receptor function |
| 6728 |
RGFP 966 |
| Potent and selective HDAC3 inhibitor |
| 1842 |
RHC 80267 |
| Diacylglycerol lipase inhibitor |
| 5311 |
RHPS 4 methosulfate |
| Telomerase inhibitor |
| 6168 |
RI 1 |
| RAD51 recombinase inhibitor |
| 6567 |
RI-STAD 2 |
| AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable |
| 6892 |
RIPGBM New |
| RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant |
| 2443 |
RITA |
| MDM2-p53 interaction inhibitor |
| 1053 |
RJR 2403 oxalate |
| Selective α4β2 nAChR agonist |
| 1271 |
RJR 2429 dihydrochloride |
| nAChR agonist; displays selectivity for α4β2, α1βγδ and α3β4 subtypes |
| 5061 |
RKI 1447 dihydrochloride |
| Potent and selective ROCK inhibitor; antitumor |
| 3393 |
RLLFT-NH2 |
| Control peptide for TFLLR-NH2 (Cat. No. 1464) |
| 5909 |
RMM 46 |
| MSK/RSK family kinase inhibitor |
| 4977 |
RN 1 dihydrochloride |
| LSD1 inhibitor |
| 3746 |
RN 1734 |
| Selective TRPV4 antagonist |
| 3745 |
RN 1747 |
| Selective TRPV4 agonist |
| 5678 |
RN 9893 hydrochloride |
| Potent and selective TRPV4 antagonist |
| 6833 |
RO 5263397 hydrochloride New |
| Potent TA1 receptor agonist |
| 3052 |
RO-3 |
| Selective P2X3 and P2X2/3 antagonist |
| 2034 |
ROS 234 dioxalate |
| Potent H3 antagonist |
| 4289 |
RP 001 hydrochloride |
| Potent S1P1 agonist |
| 1635 |
RP 67580 |
| Potent and selective NK1 antagonist |
| 5388 |
RQ 00203078 |
| Potent and selective TRPM8 antagonist; orally active |
| 5928 |
RS 09 |
| TLR4 peptide agonist; acts as an adjuvant in vivo |
| 5810 |
RS 1 |
| High affinity RAD51 activator; also CRISPR enhancer |
| 1325 |
RS 100329 hydrochloride |
| Potent, subtype-selective α1A antagonist |
| 1050 |
RS 102221 hydrochloride |
| Selective 5-HT2C antagonist |
| 2089 |
RS 102895 hydrochloride |
| CCR2b chemokine receptor antagonist |
| 2993 |
RS 127445 hydrochloride |
| High affinity and selective 5-HT2B antagonist |
| 1015 |
RS 16566 dihydrochloride |
| 5-HT3 ligand; shows affinity for zacopride binding site |
| 0985 |
RS 17053 hydrochloride |
| α1A antagonist |
| 0728 |
RS 23597-190 hydrochloride |
| 5-HT4 antagonist |
| 3315 |
RS 25344 hydrochloride |
| Potent PDE4 inhibitor |
| 0991 |
RS 39604 hydrochloride |
| 5-HT4 antagonist |
| 0889 |
RS 45041-190 hydrochloride |
| High affinity I2 ligand. Highly selective |
| 2517 |
RS 504393 |
| Highly selective CCR2 chemokine receptor antagonist |
| 0988 |
RS 56812 hydrochloride |
| 5-HT3 partial agonist |
| 0989 |
RS 67333 hydrochloride |
| 5-HT4 partial agonist |
| 0990 |
RS 67506 hydrochloride |
| 5-HT4 partial agonist |
| 0987 |
RS 79948 hydrochloride |
| Potent and selective α2 antagonist |
| 6118 |
1S,3R-RSL3 |
| Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4) |
| 5138 |
RSVA 405 |
| AMPK activator; also STAT3 inhibitor |
| 0912 |
RU 24969 hemisuccinate |
| 5-HT1A and 5-HT1B agonist |
| 1672 |
RU 28318, potassium salt |
| Potent, selective mineralocorticoid receptor antagonist |
| 4886 |
RU-SKI 43 hydrochloride |
| Hedgehog acyltransferase (Hhat) inhibitor; cell permeable |
| 3744 |
RVD-Hpα |
| Selective CB1 agonist; also CB2 PAM |
| 2719 |
RWJ 21757 |
| Toll-like receptor 7 (TLR7) agonist |
| 4227 |
RWJ 50271 |
| Inhibitor of LFA-1/ICAM mediated cell adhesion |
| 3935 |
RWJ 52353 |
| α2D agonist |
| 2614 |
RWJ 56110 |
| Selective PAR1 antagonist |
| 2999 |
RWJ 67657 |
| Potent, selective p38α and p38β inhibitor |
| 1324 |
RX 821002 hydrochloride |
| Potent, selective α2D antagonist |
| 1239 |
Ac-RYYRIK-NH2 |
| High affinity NOP ligand |
| 1387 |
Ac-RYYRWK-NH2 |
| Potent, selective NOP partial agonist peptide |
| 2222 |
Rac1 Inhibitor F56, control peptide |
| Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221) |
| 2221 |
Rac1 Inhibitor W56 |
| Selective inhibitor of Rac1-GEF interaction |
| 1810 |
Raclopride |
| Potent and selective D2 and D3 antagonist |
| 1589 |
Radicicol |
| Hsp90 inhibitor. Antifungal antibiotic |
| 4029 |
Ralfinamide mesylate |
| Na+ channel blocker |
| 2280 |
Raloxifene hydrochloride |
| Selective estrogen receptor modulator (SERM) |
| 5250 |
Ramipril |
| Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor |
| 1967 |
Ranitidine hydrochloride |
| Selective H2 antagonist |
| 3118 |
Ranolazine dihydrochloride |
| Antianginal, activates pyruvate dehydrogenase |
| 1292 |
Rapamycin |
| mTOR inhibitor; immunosuppressant |
| 6760 |
Raphin 1 |
| Inhibitor of the regulatory subunit PPP1R15B of protein phosphatase 1; orally bioavailable and brain penetrant |
| 4308 |
Rasagiline mesylate |
| Selective and irreversible MAO-B inhibitor |
| 0891 |
Rauwolscine hydrochloride |
| α2 antagonist |
| 6640 |
ReZolve-ER™ |
| Fluorescent ER and plasma membrane stain |
| 1982 |
Reboxetine mesylate |
| Potent and selective noradrenalin uptake inhibitor; orally active |
| 3284 |
Rec 15/2615 dihydrochloride |
| Selective α1B antagonist |
| 1622 |
Remacemide hydrochloride |
| NMDA antagonist; blocks ion channel and allosteric modulatory site |
| 5193 |
Remodelin |
| N-acetyltransferase 10 (NAT10) inhibitor |
| 0916 |
Remoxipride hydrochloride |
| Selective D2-like antagonist |
| 3742 |
RepSox |
| Potent and selective inhibitor of TGF-βRI |
| 3805 |
Repaglinide |
| Kir6 (KATP) channel blocker |
| 6957 |
Reparixin L-lysine salt |
| Potent CXCR1 and CXCR2 allosteric antagonist |
| 2742 |
Reserpine |
| Inhibitor of vesicular monoamine transport |
| 4536 |
Resiquimod |
| Toll-like receptor 7 (TLR7) agonist |
| 1418 |
Resveratrol |
| Cyclooxygenase inhibitor |
| 6233 |
Retigabine |
| KV7 channel activator |
| 0695 |
Retinoic acid |
| Endogenous retinoic acid receptor agonist |
| 3722 |
Reversan |
| Selective MRP1 and P-gp inhibitor |
| 6867 |
Rhein |
| FTO (mRNA N6-methyladenine demethylase) inhibitor; also inhibits ALKBH2 and ALKBH3 |
| 5003 |
Rhosin hydrochloride |
| Rho inhibitor |
| 4501 |
Ribavirin |
| Blocks eIF4E activity; antiviral guanosine analog |
| 7050 |
Ribociclib |
| Dual cdk4/cdk6 inhibitor; orally bioavailable |
| 4121 |
Rifampicin |
| Pregnane X receptor agonist; antibiotic |
| 5359 |
Rifaximin |
| Pregnane X receptor agonist; antibiotic |
| 0790 |
Rilmenidine hemifumarate |
| α2 agonist. Also I1 ligand |
| 0768 |
Riluzole hydrochloride |
| GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels |
| 1497 |
Rimcazole dihydrochloride |
| σ2 antagonist. Also DAT inhibitor |
| 3504 |
Risedronate |
| Farnesyl diphosphate (FPP) synthase inhibitor |
| 2865 |
Risperidone |
| 5-HT2A antagonist; also D2 antagonist; atypical antipsychotic |
| 1955 |
Ritanserin |
| Potent 5-HT2 antagonist |
| 5856 |
Ritonavir |
| HIV-1 and HIV-2 protease inhibitor |
| 4440 |
Rivastigmine tartrate |
| Dual AChE and BChE inhibitor |
| 5136 |
Rizatriptan benzoate |
| Potent 5-HT1B and 5-HT1D agonist |
| 4348 |
Ro 01-6128 |
| Positive allosteric modulator of mGlu1 receptors |
| 2005 |
Ro 04-5595 hydrochloride |
| GluN2B-selective NMDA antagonist |
| 2911 |
Ro 04-6790 |
| Potent and selective 5-HT6 antagonist |
| 2188 |
Ro 0437626 |
| Selective P2X1 antagonist |
| 2272 |
Ro 08-2750 |
| Inhibits NGF binding to p75NTR and TrkA |
| 2329 |
Ro 10-5824 dihydrochloride |
| Selective D4 partial agonist |
| 1778 |
Ro 106-9920 |
| Inhibitor of NF-κB activation |
| 4268 |
Ro 1138452 hydrochloride |
| Selective prostacyclin IP receptor antagonist |
| 1997 |
Ro 15-4513 |
| Benzodiazepine partial inverse agonist |
| 1995 |
Ro 19-4603 |
| Benzodiazepine inverse agonist |
| 0415 |
Ro 20-1724 |
| PDE4 inhibitor |
| 1594 |
Ro 25-6981 maleate |
| GluN2B-selective NMDA antagonist |
| 1794 |
Ro 26-4550 trifluoroacetate |
| Competitive inhibitor of IL-2/ IL-2Rα receptor interaction |
| 2002 |
Ro 31-8220 mesylate |
| Protein kinase inhibitor |
| 1587 |
Ro 32-0432 hydrochloride |
| Potent, orally active PKC inhibitor |
| 5968 |
Ro 3280 |
| Potent and selective PLK1 inhibitor |
| 4181 |
Ro 3306 |
| Cdk1 inhibitor |
| 5389 |
Ro 48-8071 fumarate |
| 2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis |
| 4694 |
Ro 5-3335 |
| Core binding factor inhibitor; attenuates hematopoiesis |
| 4391 |
Ro 51 |
| Potent P2X3, P2X2/3 antagonist |
| 1854 |
Ro 60-0175 fumarate |
| Potent, selective 5-HT2C agonist |
| 3254 |
Ro 61-8048 |
| Potent kynurenine 3-monooxygenase (KMO) inhibitor |
| 2913 |
Ro 64-5229 |
| Selective, non-competitive mGlu2 antagonist |
| 4347 |
Ro 67-4853 |
| Positive allosteric modulator of group I mGlu receptors |
| 4346 |
Ro 67-7476 |
| Positive allosteric modulator of mGlu1 receptors |
| 5913 |
Ro 6842262 |
| Potent LPA1 antagonist |
| 3343 |
Ro 8-4304 hydrochloride |
| GluN2B-selective NMDA antagonist |
| 2408 |
Ro 90-7501 |
| Inhibitor of Aβ42 fibril formation |
| 6641 |
Roflumilast |
| Potent and selective PDE4 inhibitor |
| 0905 |
Rolipram |
| PDE4 inhibitor |
| 1349 |
(R)-(-)-Rolipram |
| PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905) |
| 1350 |
(S)-(+)-Rolipram |
| PDE4 inhibitor. Less active enantiomer of rolipram (Cat. No. 0905) |
| 3680 |
Ropinirole |
| Selective D2-like agonist |
| 5543 |
Ropinirole - d7 |
| Deuterated ropinirole (Cat. No. 3680) |
| 1332 |
Roscovitine |
| Cdk inhibitor |
| 5168 |
Rose Bengal |
| Stains exposed epithelium in eye. Also VGlut and VMAT inhibitor |
| 5325 |
Rosiglitazone |
| Potent and selective PPARγ agonist; antidiabetic agent |
| 0630 |
Rosmarinic acid |
| Anti-inflammatory, cytostatic and antiviral; GPR35 agonist |
| 5315 |
Rostafuroxin |
| Na+/K+ ATPase modulator; antihypertensive agent |
| 6343 |
Rosuvastatin calcium |
| Potent HMG-CoA reductase inhibitor |
| 3616 |
Rotenone |
| Inhibits complex I of the mitochondrial electron transport chain |
| 3896 |
Rotigotine hydrochloride |
| D2 and D3 agonist |
| 1610 |
Rottlerin |
| Reported PKCδ inhibitor |
| 1559 |
Roxindole hydrochloride |
| Dopamine D2 autoreceptor agonist. Also has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter |
| 5524 |
Rp-8-pCPT-cGMPS sodium |
| PKG inhibitor |
| 3400 |
RuBi-GABA |
| Caged GABA; excitable at visible wavelengths |
| 3574 |
RuBi-Glutamate |
| Caged glutamate; excited by visible wavelengths |
| 3855 |
RuBi-Nicotine |
| Caged nicotine; rapidly excitable by visible light |
| 4709 |
RuBi GABA trimethylphosphine |
| Caged GABA; inhibits neural activity |
| 6230 |
Rucaparib camsylate |
| PARP inhibitor |
| 3828 |
Rufinamide |
| Prolongs inactivation of sodium channels; anticonvulsant |
| 6414 |
Rupintrivir |
| Potent and selective irreversible human rhinovirus 3C protease inhibitor |
| 1439 |
Ruthenium Red |
| Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels |
| 7064 |
Ruxolitinib New |
| Potent and selective JAK1/JAK2 inhibitor; orally bioavailable |
| 7048 |
Ruxolitinib phosphate New |
| Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor |
| 1329 |
Ryanodine |
| Ca2+ release inhibitor |
| 2609 |
Ryuvidine |
| SETD8 inhibitor; also CDK4 inhibitor |