Cat. No. | Product Name / Activity |
---|---|
6530 | R 121919 hydrochloride |
High affinity CRF1 antagonist; orally bioavailable | |
4964 | R 1485 dihydrochloride |
Selective and high affinity 5-HT6 antagonist | |
4885 | R 1530 |
Multi-RTK inhibitor; inhibits angiogenesis | |
5288 | R 268712 |
Potent and selective inhibitor of TGF-βRI | |
5494 | R 547 |
Potent and selective cdk inhibitor; orally bioavailable | |
3815 | R 568 hydrochloride |
Positive allosteric modulator of human calcium-sensing receptor (CaSR) | |
2194 | R 59-022 |
Diacylglycerol kinase inhibitor; increases PKC activity | |
5432 | R 7050 |
Inhibitor of TNF-α receptor 1 signaling | |
3407 | R 715 |
Potent and selective B1 antagonist | |
3226 | R 892 |
Potent and selective B1 antagonist | |
1742 | R-96544 hydrochloride |
Potent, selective 5-HT2A antagonist | |
6048 | R-BC154 |
High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs | |
6054 | R162 |
Glutamate dehydrogenase (GDH1) inhibitor | |
2144 | R18 |
Inhibitor of 14.3.3 proteins | |
1577 | L-R4W2 |
TRPV1 antagonist peptide | |
4592 | R8-T198wt |
Pim-1 kinase inhibitor | |
5707 | RA 839 |
Nrf2 activator; inhibits Nrf2/Keap1 interaction | |
6649 | RADA |
Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria | |
6015 | RAF 265 |
Raf kinase and VEGFR-2 inhibitor | |
6259 | RAGE antagonist peptide |
RAGE antagonist | |
5411 | RBC8 |
RalA and RalB inhibitor | |
3139 | RC 160 |
sst analog | |
7066 | RCGD 423 |
gp130 modulator; activates JAK/STAT signaling | |
6845 | RCM 1 |
FOXM1 inhibitor | |
3841 | RETF-4NA |
Selective chymase substrate | |
3214 | RETRA hydrochloride |
Antitumor agent; suppresses mutant p53-bearing cancer cells | |
3672 | RF 9 |
Selective NPFF1 and NPFF2 antagonist | |
4683 | RFRP 3 (human) |
NPFF1 agonist; GnIH homolog | |
5677 | RFRP-1 (human) |
Potent NPFF receptor agonist | |
5761 | RG 102240 |
Gene switch ligand for use in inducible gene expression systems | |
3295 | RG 108 |
Non-nucleoside DNA methyltransferase inhibitor | |
3498 | RGDS peptide |
Integrin binding sequence; inhibits integrin receptor function | |
6728 | RGFP 966 |
Potent and selective HDAC3 inhibitor | |
1842 | RHC 80267 |
Diacylglycerol lipase inhibitor | |
5311 | RHPS 4 methosulfate |
Telomerase inhibitor | |
6168 | RI 1 |
RAD51 recombinase inhibitor | |
6567 | RI-STAD 2 |
AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable | |
6892 | RIPGBM |
RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant | |
2443 | RITA |
MDM2-p53 interaction inhibitor | |
1053 | RJR 2403 oxalate |
Selective α4β2 nAChR agonist | |
1271 | RJR 2429 dihydrochloride |
nAChR agonist; displays selectivity for α4β2, α1βγδ and α3β4 subtypes | |
5061 | RKI 1447 dihydrochloride |
Potent and selective ROCK inhibitor; antitumor | |
3393 | RLLFT-NH2 |
Control peptide for TFLLR-NH2 (Cat. No. 1464) | |
5909 | RMM 46 |
MSK/RSK family kinase inhibitor | |
4977 | RN 1 dihydrochloride |
LSD1 inhibitor | |
3746 | RN 1734 |
Selective TRPV4 antagonist | |
3745 | RN 1747 |
Selective TRPV4 agonist | |
5678 | RN 9893 hydrochloride |
Potent and selective TRPV4 antagonist | |
6833 | RO 5263397 hydrochloride |
Potent TA1 receptor agonist | |
3052 | RO-3 |
Selective P2X3 and P2X2/3 antagonist | |
2034 | ROS 234 dioxalate |
Potent H3 antagonist | |
4289 | RP 001 hydrochloride |
Potent S1P1 agonist | |
1635 | RP 67580 |
Potent and selective NK1 antagonist | |
5388 | RQ 00203078 |
Potent and selective TRPM8 antagonist; orally active | |
5928 | RS 09 |
TLR4 peptide agonist; acts as an adjuvant in vivo | |
5810 | RS 1 |
High affinity RAD51 activator; also CRISPR enhancer | |
1325 | RS 100329 hydrochloride |
Potent, subtype-selective α1A antagonist | |
1050 | RS 102221 hydrochloride |
Selective 5-HT2C antagonist | |
2089 | RS 102895 hydrochloride |
CCR2b chemokine receptor antagonist | |
2993 | RS 127445 hydrochloride |
High affinity and selective 5-HT2B antagonist | |
1015 | RS 16566 dihydrochloride |
5-HT3 ligand; shows affinity for zacopride binding site | |
0985 | RS 17053 hydrochloride |
α1A antagonist | |
0728 | RS 23597-190 hydrochloride |
5-HT4 antagonist | |
0991 | RS 39604 hydrochloride |
5-HT4 antagonist | |
0889 | RS 45041-190 hydrochloride |
High affinity I2 ligand. Highly selective | |
2517 | RS 504393 |
Highly selective CCR2 chemokine receptor antagonist | |
0988 | RS 56812 hydrochloride |
5-HT3 partial agonist | |
0989 | RS 67333 hydrochloride |
5-HT4 partial agonist | |
0990 | RS 67506 hydrochloride |
5-HT4 partial agonist | |
0987 | RS 79948 hydrochloride |
Potent and selective α2 antagonist | |
6118 | 1S,3R-RSL3 |
Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4) | |
5138 | RSVA 405 |
AMPK activator; also STAT3 inhibitor | |
0912 | RU 24969 hemisuccinate |
5-HT1A and 5-HT1B agonist | |
1672 | RU 28318, potassium salt |
Potent, selective mineralocorticoid receptor antagonist | |
4886 | RU-SKI 43 hydrochloride |
Hedgehog acyltransferase (Hhat) inhibitor; cell permeable | |
3744 | RVD-Hpα |
Selective CB1 agonist; also CB2 PAM | |
4227 | RWJ 50271 |
Inhibitor of LFA-1/ICAM mediated cell adhesion | |
3935 | RWJ 52353 |
α2D agonist | |
2614 | RWJ 56110 |
Selective PAR1 antagonist | |
2999 | RWJ 67657 |
Potent, selective p38α and p38β inhibitor | |
1324 | RX 821002 hydrochloride |
Potent, selective α2D antagonist | |
1239 | Ac-RYYRIK-NH2 |
High affinity NOP ligand | |
1387 | Ac-RYYRWK-NH2 |
Potent, selective NOP partial agonist peptide | |
2222 | Rac1 Inhibitor F56, control peptide |
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221) | |
2221 | Rac1 Inhibitor W56 |
Selective inhibitor of Rac1-GEF interaction | |
1810 | Raclopride |
Potent and selective D2 and D3 antagonist | |
1589 | Radicicol |
Hsp90 inhibitor. Antifungal antibiotic | |
4029 | Ralfinamide mesylate |
Na+ channel blocker | |
2280 | Raloxifene hydrochloride |
Selective estrogen receptor modulator (SERM) | |
5250 | Ramipril |
Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor | |
1967 | Ranitidine hydrochloride |
Selective H2 antagonist | |
3118 | Ranolazine dihydrochloride |
Antianginal, activates pyruvate dehydrogenase | |
1292 | Rapamycin |
mTOR inhibitor; immunosuppressant | |
6760 | Raphin 1 |
Inhibitor of the regulatory subunit PPP1R15B of protein phosphatase 1; orally bioavailable and brain penetrant | |
4308 | Rasagiline mesylate |
Selective and irreversible MAO-B inhibitor | |
0891 | Rauwolscine hydrochloride |
α2 antagonist | |
6640 | ReZolve-ER™ |
Fluorescent ER and plasma membrane stain | |
1982 | Reboxetine mesylate |
Potent and selective noradrenalin uptake inhibitor; orally active | |
3284 | Rec 15/2615 dihydrochloride |
Selective α1B antagonist | |
1622 | Remacemide hydrochloride |
NMDA antagonist; blocks ion channel and allosteric modulatory site | |
7226 | Remdesivir |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucelotide prodrug | |
5193 | Remodelin |
N-acetyltransferase 10 (NAT10) inhibitor | |
0916 | Remoxipride hydrochloride |
Selective D2-like antagonist | |
3742 | RepSox |
Potent and selective inhibitor of TGF-βRI | |
3805 | Repaglinide |
Kir6 (KATP) channel blocker | |
6957 | Reparixin L-lysine salt |
Potent CXCR1 and CXCR2 allosteric antagonist | |
2742 | Reserpine |
Inhibitor of vesicular monoamine transport | |
4536 | Resiquimod |
Toll-like receptor 7 (TLR7) agonist | |
1418 | Resveratrol |
Cyclooxygenase inhibitor | |
6233 | Retigabine |
KV7 channel activator | |
0695 | Retinoic acid |
Endogenous retinoic acid receptor agonist | |
3722 | Reversan |
Selective MRP1 and P-gp inhibitor | |
6867 | Rhein |
FTO (mRNA N6-methyladenine demethylase) inhibitor; also inhibits ALKBH2 and ALKBH3 | |
5003 | Rhosin hydrochloride |
Rho inhibitor | |
4501 | Ribavirin |
Blocks eIF4E activity; antiviral guanosine analog | |
7050 | Ribociclib |
Dual cdk4/cdk6 inhibitor; orally bioavailable | |
4121 | Rifampicin |
Pregnane X receptor agonist; antibiotic | |
5359 | Rifaximin |
Pregnane X receptor agonist; antibiotic | |
0790 | Rilmenidine hemifumarate |
α2 agonist. Also I1 ligand | |
0768 | Riluzole hydrochloride |
GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels | |
1497 | Rimcazole dihydrochloride |
σ2 antagonist. Also DAT inhibitor | |
3504 | Risedronate |
Farnesyl diphosphate (FPP) synthase inhibitor | |
2865 | Risperidone |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic | |
1955 | Ritanserin |
Potent 5-HT2 antagonist | |
5856 | Ritonavir |
HIV-1 and HIV-2 protease inhibitor | |
4440 | Rivastigmine tartrate |
Dual AChE and BChE inhibitor | |
5136 | Rizatriptan benzoate |
Potent 5-HT1B and 5-HT1D agonist | |
4348 | Ro 01-6128 |
Positive allosteric modulator of mGlu1 receptors | |
2005 | Ro 04-5595 hydrochloride |
GluN2B-selective NMDA antagonist | |
2911 | Ro 04-6790 |
Potent and selective 5-HT6 antagonist | |
2188 | Ro 0437626 |
Selective P2X1 antagonist | |
2272 | Ro 08-2750 |
Inhibits NGF binding to p75NTR and TrkA | |
2329 | Ro 10-5824 dihydrochloride |
Selective D4 partial agonist | |
1778 | Ro 106-9920 |
Inhibitor of NF-κB activation | |
4268 | Ro 1138452 hydrochloride |
Selective prostacyclin IP receptor antagonist | |
1997 | Ro 15-4513 |
Benzodiazepine partial inverse agonist | |
0415 | Ro 20-1724 |
PDE4 inhibitor | |
1594 | Ro 25-6981 maleate |
GluN2B-selective NMDA antagonist | |
2002 | Ro 31-8220 mesylate |
Protein kinase inhibitor | |
1587 | Ro 32-0432 hydrochloride |
Potent, orally active PKC inhibitor | |
5968 | Ro 3280 |
Potent and selective PLK1 inhibitor | |
4181 | Ro 3306 |
Cdk1 inhibitor | |
5389 | Ro 48-8071 fumarate |
2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis | |
4694 | Ro 5-3335 |
Core binding factor inhibitor; attenuates hematopoiesis | |
4391 | Ro 51 |
Potent P2X3 and P2X2/3 antagonist | |
1854 | Ro 60-0175 fumarate |
Potent, selective 5-HT2C agonist | |
3254 | Ro 61-8048 |
Potent kynurenine 3-monooxygenase (KMO) inhibitor | |
2913 | Ro 64-5229 |
Selective, non-competitive mGlu2 antagonist | |
4347 | Ro 67-4853 |
Positive allosteric modulator of group I mGlu receptors | |
4346 | Ro 67-7476 |
Positive allosteric modulator of mGlu1 receptors | |
5913 | Ro 6842262 |
Potent LPA1 antagonist | |
2408 | Ro 90-7501 |
Inhibitor of Aβ42 fibril formation | |
6641 | Roflumilast |
Potent and selective PDE4 inhibitor | |
0905 | Rolipram |
PDE4 inhibitor | |
1349 | (R)-(-)-Rolipram |
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905) | |
3680 | Ropinirole |
Selective D2-like agonist | |
5543 | Ropinirole - d7 |
Deuterated ropinirole (Cat. No. 3680) | |
1332 | Roscovitine |
Cdk inhibitor | |
5168 | Rose Bengal |
Stains exposed epithelium in eye. Also VGlut and VMAT inhibitor | |
5325 | Rosiglitazone |
Potent and selective PPARγ agonist; antidiabetic agent | |
0630 | Rosmarinic acid |
GPR35 agonist; anti-inflammatory, cytostatic and antiviral | |
5315 | Rostafuroxin |
Na+/K+ ATPase modulator; antihypertensive agent | |
6343 | Rosuvastatin calcium |
Potent HMG-CoA reductase inhibitor | |
3616 | Rotenone |
Inhibits complex I of the mitochondrial electron transport chain | |
3896 | Rotigotine hydrochloride |
D2 and D3 agonist | |
1610 | Rottlerin |
Reported PKCδ inhibitor | |
1559 | Roxindole hydrochloride |
Dopamine D2 autoreceptor agonist. Also has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter | |
5524 | Rp-8-pCPT-cGMPS sodium |
PKG inhibitor | |
3400 | RuBi-GABA |
Caged GABA; excitable at visible wavelengths | |
3574 | RuBi-Glutamate |
Caged glutamate; excited by visible wavelengths | |
3855 | RuBi-Nicotine |
Caged nicotine; rapidly excitable by visible light | |
4709 | RuBi GABA trimethylphosphine |
Caged GABA; inhibits neural activity | |
6230 | Rucaparib camsylate |
PARP inhibitor | |
3828 | Rufinamide |
Prolongs inactivation of sodium channels; anticonvulsant | |
6414 | Rupintrivir |
Potent and selective irreversible human rhinovirus 3Cpro inhibitor | |
1439 | Ruthenium Red |
Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels | |
7064 | Ruxolitinib |
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable | |
7048 | Ruxolitinib phosphate |
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor | |
1329 | Ryanodine |
Ca2+ release inhibitor | |
2609 | Ryuvidine |
SETD8 inhibitor; also CDK4 inhibitor |