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Displaying Products Alphabetically by Name (R)

Cat. No. Product Name / Activity
6530 R 121919 hydrochloride
High affinity CRF1 antagonist; orally bioavailable
4964 R 1485 dihydrochloride
Selective and high affinity 5-HT6 antagonist
4885 R 1530
Multi-RTK inhibitor; inhibits angiogenesis
5288 R 268712
Potent and selective inhibitor of TGF-βRI
5494 R 547
Potent and selective cdk inhibitor; orally bioavailable
3815 R 568 hydrochloride
Positive allosteric modulator of human calcium-sensing receptor (CaSR)
2194 R 59-022
Diacylglycerol kinase inhibitor; increases PKC activity
5432 R 7050
Inhibitor of TNF-α receptor 1 signaling
3407 R 715
Potent and selective B1 antagonist
3226 R 892
Potent and selective B1 antagonist
1742 R-96544 hydrochloride
Potent, selective 5-HT2A antagonist
6048 R-BC154
High affinity fluorescent a4 beta 1/a9 beta 1 inhibitor; mobilizes HSCs
6054 R162
Glutamate dehydrogenase (GDH1) inhibitor
2144 R18
Inhibitor of 14.3.3 proteins
1577 L-R4W2
TRPV1 antagonist peptide
4592 R8-T198wt
Pim-1 kinase inhibitor
5707 RA 839
Nrf2 activator; inhibits Nrf2/Keap1 interaction
6649 RADA
Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria
6015 RAF 265
Raf kinase and VEGFR-2 inhibitor
6259 RAGE antagonist peptide
RAGE antagonist
5411 RBC8
RalA and RalB inhibitor
3139 RC 160
sst analog
7066 RCGD 423
gp130 modulator; activates JAK/STAT signaling
6845 RCM 1
FOXM1 inhibitor
3841 RETF-4NA
Selective chymase substrate
3214 RETRA hydrochloride
Antitumor agent; suppresses mutant p53-bearing cancer cells
3672 RF 9
Selective NPFF1 and NPFF2 antagonist
4683 RFRP 3 (human)
NPFF1 agonist; GnIH homolog
5677 RFRP-1 (human)
Potent NPFF receptor agonist
5761 RG 102240
Gene switch ligand for use in inducible gene expression systems
3295 RG 108
Non-nucleoside DNA methyltransferase inhibitor
3498 RGDS peptide
Integrin binding sequence; inhibits integrin receptor function
6728 RGFP 966
Potent and selective HDAC3 inhibitor
1842 RHC 80267
Diacylglycerol lipase inhibitor
5311 RHPS 4 methosulfate
Telomerase inhibitor
6168 RI 1
RAD51 recombinase inhibitor
6567 RI-STAD 2
AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable
6892 RIPGBM
RIPK2 modulator; pro-drug of cRIPGM; orally bioavailable and brain penetrant
2443 RITA
MDM2-p53 interaction inhibitor
1053 RJR 2403 oxalate
Selective α4β2 nAChR agonist
1271 RJR 2429 dihydrochloride
nAChR agonist; displays selectivity for α4β2, α1βγδ and α3β4 subtypes
5061 RKI 1447 dihydrochloride
Potent and selective ROCK inhibitor; antitumor
3393 RLLFT-NH2
Control peptide for TFLLR-NH2 (Cat. No. 1464)
5909 RMM 46
MSK/RSK family kinase inhibitor
4977 RN 1 dihydrochloride
LSD1 inhibitor
3746 RN 1734
Selective TRPV4 antagonist
3745 RN 1747
Selective TRPV4 agonist
5678 RN 9893 hydrochloride
Potent and selective TRPV4 antagonist
6833 RO 5263397 hydrochloride
Potent TA1 receptor agonist
3052 RO-3
Selective P2X3 and P2X2/3 antagonist
2034 ROS 234 dioxalate
Potent H3 antagonist
4289 RP 001 hydrochloride
Potent S1P1 agonist
1635 RP 67580
Potent and selective NK1 antagonist
5388 RQ 00203078
Potent and selective TRPM8 antagonist; orally active
5928 RS 09
TLR4 peptide agonist; acts as an adjuvant in vivo
5810 RS 1
High affinity RAD51 activator; also CRISPR enhancer
1325 RS 100329 hydrochloride
Potent, subtype-selective α1A antagonist
1050 RS 102221 hydrochloride
Selective 5-HT2C antagonist
2089 RS 102895 hydrochloride
CCR2b chemokine receptor antagonist
2993 RS 127445 hydrochloride
High affinity and selective 5-HT2B antagonist
1015 RS 16566 dihydrochloride
5-HT3 ligand; shows affinity for zacopride binding site
0985 RS 17053 hydrochloride
α1A antagonist
0728 RS 23597-190 hydrochloride
5-HT4 antagonist
3315 RS 25344 hydrochloride
Potent PDE4 inhibitor
0991 RS 39604 hydrochloride
5-HT4 antagonist
0889 RS 45041-190 hydrochloride
High affinity I2 ligand. Highly selective
2517 RS 504393
Highly selective CCR2 chemokine receptor antagonist
0988 RS 56812 hydrochloride
5-HT3 partial agonist
0989 RS 67333 hydrochloride
5-HT4 partial agonist
0990 RS 67506 hydrochloride
5-HT4 partial agonist
0987 RS 79948 hydrochloride
Potent and selective α2 antagonist
6118 1S,3R-RSL3
Induces ferroptosis; inhibits glutathione peroxidase 4 (GPX4)
5138 RSVA 405
AMPK activator; also STAT3 inhibitor
0912 RU 24969 hemisuccinate
5-HT1A and 5-HT1B agonist
1672 RU 28318, potassium salt
Potent, selective mineralocorticoid receptor antagonist
4886 RU-SKI 43 hydrochloride
Hedgehog acyltransferase (Hhat) inhibitor; cell permeable
3744 RVD-Hpα
Selective CB1 agonist; also CB2 PAM
2719 RWJ 21757
Toll-like receptor 7 (TLR7) agonist
4227 RWJ 50271
Inhibitor of LFA-1/ICAM mediated cell adhesion
3935 RWJ 52353
α2D agonist
2614 RWJ 56110
Selective PAR1 antagonist
2999 RWJ 67657
Potent, selective p38α and p38β inhibitor
1324 RX 821002 hydrochloride
Potent, selective α2D antagonist
1239 Ac-RYYRIK-NH2
High affinity NOP ligand
1387 Ac-RYYRWK-NH2
Potent, selective NOP partial agonist peptide
2222 Rac1 Inhibitor F56, control peptide
Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221 Rac1 Inhibitor W56
Selective inhibitor of Rac1-GEF interaction
1810 Raclopride
Potent and selective D2 and D3 antagonist
1589 Radicicol
Hsp90 inhibitor. Antifungal antibiotic
4029 Ralfinamide mesylate
Na+ channel blocker
2280 Raloxifene hydrochloride
Selective estrogen receptor modulator (SERM)
5250 Ramipril
Non-peptide, competitive angiotensin-converting enzyme (ACE) inhibitor
1967 Ranitidine hydrochloride
Selective H2 antagonist
3118 Ranolazine dihydrochloride
Antianginal, activates pyruvate dehydrogenase
1292 Rapamycin
mTOR inhibitor; immunosuppressant
6760 Raphin 1
Inhibitor of the regulatory subunit PPP1R15B of protein phosphatase 1; orally bioavailable and brain penetrant
4308 Rasagiline mesylate
Selective and irreversible MAO-B inhibitor
0891 Rauwolscine hydrochloride
α2 antagonist
6640 ReZolve-ER™
Fluorescent ER and plasma membrane stain
1982 Reboxetine mesylate
Potent and selective noradrenalin uptake inhibitor; orally active
3284 Rec 15/2615 dihydrochloride
Selective α1B antagonist
1622 Remacemide hydrochloride
NMDA antagonist; blocks ion channel and allosteric modulatory site
5193 Remodelin
N-acetyltransferase 10 (NAT10) inhibitor
0916 Remoxipride hydrochloride
Selective D2-like antagonist
3742 RepSox
Potent and selective inhibitor of TGF-βRI
3805 Repaglinide
Kir6 (KATP) channel blocker
6957 Reparixin L-lysine salt
Potent CXCR1 and CXCR2 allosteric antagonist
2742 Reserpine
Inhibitor of vesicular monoamine transport
4536 Resiquimod
Toll-like receptor 7 (TLR7) agonist
1418 Resveratrol
Cyclooxygenase inhibitor
6233 Retigabine
KV7 channel activator
0695 Retinoic acid
Endogenous retinoic acid receptor agonist
3722 Reversan
Selective MRP1 and P-gp inhibitor
6867 Rhein
FTO (mRNA N6-methyladenine demethylase) inhibitor; also inhibits ALKBH2 and ALKBH3
5003 Rhosin hydrochloride
Rho inhibitor
4501 Ribavirin
Blocks eIF4E activity; antiviral guanosine analog
7050 Ribociclib
Dual cdk4/cdk6 inhibitor; orally bioavailable
4121 Rifampicin
Pregnane X receptor agonist; antibiotic
5359 Rifaximin
Pregnane X receptor agonist; antibiotic
0790 Rilmenidine hemifumarate
α2 agonist. Also I1 ligand
0768 Riluzole hydrochloride
GABA uptake inhibitor; also inhibits glutamate release and blocks NaV channels
1497 Rimcazole dihydrochloride
σ2 antagonist. Also DAT inhibitor
3504 Risedronate
Farnesyl diphosphate (FPP) synthase inhibitor
2865 Risperidone
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
1955 Ritanserin
Potent 5-HT2 antagonist
5856 Ritonavir
HIV-1 and HIV-2 protease inhibitor
4440 Rivastigmine tartrate
Dual AChE and BChE inhibitor
5136 Rizatriptan benzoate
Potent 5-HT1B and 5-HT1D agonist
4348 Ro 01-6128
Positive allosteric modulator of mGlu1 receptors
2005 Ro 04-5595 hydrochloride
GluN2B-selective NMDA antagonist
2911 Ro 04-6790
Potent and selective 5-HT6 antagonist
2188 Ro 0437626
Selective P2X1 antagonist
2272 Ro 08-2750
Inhibits NGF binding to p75NTR and TrkA
2329 Ro 10-5824 dihydrochloride
Selective D4 partial agonist
1778 Ro 106-9920
Inhibitor of NF-κB activation
4268 Ro 1138452 hydrochloride
Selective prostacyclin IP receptor antagonist
1997 Ro 15-4513
Benzodiazepine partial inverse agonist
1995 Ro 19-4603
Benzodiazepine inverse agonist
0415 Ro 20-1724
PDE4 inhibitor
1594 Ro 25-6981 maleate
GluN2B-selective NMDA antagonist
1794 Ro 26-4550 trifluoroacetate
Competitive inhibitor of IL-2/ IL-2Rα receptor interaction
2002 Ro 31-8220 mesylate
Protein kinase inhibitor
1587 Ro 32-0432 hydrochloride
Potent, orally active PKC inhibitor
5968 Ro 3280
Potent and selective PLK1 inhibitor
4181 Ro 3306
Cdk1 inhibitor
5389 Ro 48-8071 fumarate
2,3-Oxidosqualene cyclase (OSC) inhibitor; blocks cholesterol synthesis
4694 Ro 5-3335
Core binding factor inhibitor; attenuates hematopoiesis
4391 Ro 51
Potent P2X3, P2X2/3 antagonist
1854 Ro 60-0175 fumarate
Potent, selective 5-HT2C agonist
3254 Ro 61-8048
Potent kynurenine 3-monooxygenase (KMO) inhibitor
2913 Ro 64-5229
Selective, non-competitive mGlu2 antagonist
4347 Ro 67-4853
Positive allosteric modulator of group I mGlu receptors
4346 Ro 67-7476
Positive allosteric modulator of mGlu1 receptors
5913 Ro 6842262
Potent LPA1 antagonist
3343 Ro 8-4304 hydrochloride
GluN2B-selective NMDA antagonist
2408 Ro 90-7501
Inhibitor of Aβ42 fibril formation
6641 Roflumilast
Potent and selective PDE4 inhibitor
0905 Rolipram
PDE4 inhibitor
1349 (R)-(-)-Rolipram
PDE4 inhibitor. More active enantiomer of rolipram (Cat. No. 0905)
1350 (S)-(+)-Rolipram
PDE4 inhibitor. Less active enantiomer of rolipram (Cat. No. 0905)
3680 Ropinirole
Selective D2-like agonist
5543 Ropinirole - d7
Deuterated ropinirole (Cat. No. 3680)
1332 Roscovitine
Cdk inhibitor
5168 Rose Bengal
Stains exposed epithelium in eye. Also VGlut and VMAT inhibitor
5325 Rosiglitazone
Potent and selective PPARγ agonist; antidiabetic agent
0630 Rosmarinic acid
Anti-inflammatory, cytostatic and antiviral; GPR35 agonist
5315 Rostafuroxin
Na+/K+ ATPase modulator; antihypertensive agent
6343 Rosuvastatin calcium
Potent HMG-CoA reductase inhibitor
3616 Rotenone
Inhibits complex I of the mitochondrial electron transport chain
3896 Rotigotine hydrochloride
D2 and D3 agonist
1610 Rottlerin
Reported PKCδ inhibitor
1559 Roxindole hydrochloride
Dopamine D2 autoreceptor agonist. Also has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter
5524 Rp-8-pCPT-cGMPS sodium
PKG inhibitor
3400 RuBi-GABA
Caged GABA; excitable at visible wavelengths
3574 RuBi-Glutamate
Caged glutamate; excited by visible wavelengths
3855 RuBi-Nicotine
Caged nicotine; rapidly excitable by visible light
4709 RuBi GABA trimethylphosphine
Caged GABA; inhibits neural activity
6230 Rucaparib camsylate
PARP inhibitor
3828 Rufinamide
Prolongs inactivation of sodium channels; anticonvulsant
6414 Rupintrivir
Potent and selective irreversible human rhinovirus 3C protease inhibitor
1439 Ruthenium Red
Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels
7064 Ruxolitinib
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
7048 Ruxolitinib phosphate
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
1329 Ryanodine
Ca2+ release inhibitor
2609 Ryuvidine
SETD8 inhibitor; also CDK4 inhibitor

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