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Endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Lemos et al (2002) Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 135 1743 PMID: 11934815
Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45 PMID: 10967201
Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 100 8258 PMID: 12829792
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Keywords: Angiotensin (1-7), Angiotensin (1-7) supplier, Vasorelaxant, peptide, AT, Receptors, Non-Selective, Angiotensin, agonists, Mas, [Ile5]Angiotensin, I, (1-7), Ang-(1-7), Non-selective, 1562, Tocris Bioscience
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Peptide Hormone Receptors Product ListingUpdated
A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:
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