Endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
References are publications that support the biological activity of the product.
Lemos et al (2002) Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats. Br.J.Pharmacol. 135 1743 PMID: 11934815
Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45 PMID: 10967201
Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. 100 8258 PMID: 12829792
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Keywords: Angiotensin (1-7), Angiotensin (1-7) supplier, Vasorelaxant, peptide, AT, Receptors, Non-Selective, Angiotensin, agonists, Mas, [Ile5]Angiotensin, I, (1-7), Ang-(1-7), Non-selective, 1562, Tocris Bioscience
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