All ProductsDisplaying Products Alphabetically by Name (M)
| Cat. No. | Product Name / Activity |
|---|---|
| 5807 | M 084 hydrochloride |
| TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic | |
| 6067 | M 30 dihydrochloride |
| Potent and non-selective MAO inhibitor; also an iron chelator and antioxidant | |
| 1941 | m-3M3FBS |
| Phospholipase C activator | |
| 1942 | o-3M3FBS |
| Inactive analog of m-3M3FBS (Cat. No. 1941) | |
| 3425 | M40 |
| Potent, non-selective galanin receptor antagonist | |
| 7754 | M4K2163 dihydrochloride New |
| Potent and selective ALK2 inhibitor | |
| 2697 | M617 |
| Selective GAL1 agonist | |
| 5705 | M62812 |
| TLR-4 inhibitor | |
| 5324 | M8 B hydrochloride |
| Potent and selective TRPM8 channel blocker | |
| 2698 | M871 |
| Selective GAL2 antagonist | |
| 6799 | MB 0223 |
| Dynamin-related GTPase DRP1 partial inhibitor | |
| 6618 | MB 05032 |
| Potent FBPase inhibitor; promotes HSC expansion | |
| 4077 | MC 1568 |
| Selective HDAC class IIa inhibitor | |
| 5727 | MC 1742 |
| Potent class I and IIb HDAC inhibitor | |
| 3806 | MCH (human, mouse, rat) |
| Potent endogenous MCH agonist | |
| 0336 | (RS)-MCPG |
| Non-selective mGlu antagonist | |
| 3696 | (RS)-MCPG disodium salt |
| Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336) | |
| 0337 | (S)-MCPG |
| Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336) | |
| 7195 | MCU i4 |
| Negative modulator of mitochondrial Ca2+ uniporter (MCU) | |
| 7503 | MD13 |
| Potent MIF Degrader (PROTAC®) | |
| 7504 | MD15 |
| Negative control for MD13 (Cat. No. 7503) | |
| 4173 | MDL 100907 |
| Potent and selective 5-HT2A antagonist | |
| 0870 | MDL 11,939 |
| 5-HT2A antagonist | |
| 0640 | MDL 72222 |
| 5-HT3 antagonist | |
| 5887 | MES, free acid |
| Commonly used buffer | |
| 6718 | ±-MF 094 |
| Selective USP30 inhibitor | |
| 1748 | MG 132 |
| Proteasome and calpain inhibitor. Inhibits NF-κB activation | |
| 6033 | (R)-MG 132 |
| Potent 20S proteasome inhibitor | |
| 1356 | MG 624 |
| α7 neuronal nAChR antagonist | |
| 5604 | MI 14 |
| Potent and selective PI 4-kinase IIIβ inhibitor | |
| 4848 | MI 2 (MALT1 inhibitor) |
| MALT1 inhibitor | |
| 3362 | MIRA-1 |
| Restores mutant p53 activity; proapoptotic | |
| 4415 | MK 0343 |
| GABAA partial agonist; displays subtype selectivity | |
| 5272 | MK 0677 |
| High affinity ghrelin receptor agonist | |
| 4622 | MK 1903 |
| Potent and selective GPR109A (HCA2) agonist | |
| 0941 | MK 212 hydrochloride |
| 5-HT2C agonist | |
| 5842 | MK 386 |
| Potent, selective human type 1 5α-reductase inhibitor | |
| 2338 | MK 571 |
| Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor | |
| 0924 | (+)-MK 801 maleate |
| Non-competitive NMDA antagonist; acts at ion channel site | |
| 0955 | (-)-MK 801 maleate |
| NMDA antagonist; less active enantiomer of (+)-MK 801 | |
| 1311 | MK 886 |
| Inhibitor of 5-lipoxygenase-activating protein (FLAP) | |
| 5547 | MK6-83 |
| TRPML channel activator | |
| 4621 | MKT 077 |
| Binds mot-2; selectively cytotoxic in cancer cells | |
| 4854 | ML 00253764 hydrochloride |
| Melanocortin MC4 receptor antagonist; brain penetrant | |
| 4899 | ML 120B dihydrochloride |
| Novel IKK2-selective inhibitor | |
| 4354 | ML 130 |
| Inhibits NOD1-induced NF-κB activation | |
| 4549 | ML 133 hydrochloride |
| Kir2 channel blocker | |
| 4266 | ML 141 |
| Selective Cdc42 Rho family inhibitor | |
| 4172 | ML 145 |
| GPR35 antagonist | |
| 5161 | ML 154 |
| Potent Neuropeptide S receptor antagonist | |
| 4570 | ML 161 |
| Inhibits PAR1-mediated platelet activation | |
| 4957 | ML 179 |
| Selective liver receptor homolog 1 (LRH1) inverse agonist | |
| 6668 | ML 184 |
| Selective GPR55 agonist; also promotes NSC proliferation and differentiation | |
| 4866 | ML 190 |
| Selective κ opioid receptor antagonist | |
| 4860 | ML 193 |
| Potent, selective GPR55 antagonist | |
| 4732 | ML 204 |
| Selective TRPC4 inhibitor | |
| 5987 | (±)-ML 209 |
| RORγt inverse agonist; suppresses Th17 cell differentiation | |
| 6429 | ML 210 |
| Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis | |
| 4519 | ML 213 |
| KV7.2 and KV7.4 channel opener | |
| 4507 | ML 218 hydrochloride |
| CaV3.x blocker | |
| 4748 | ML 221 |
| Apelin antagonist | |
| 5966 | ML 233 |
| Non-peptide apelin agonist | |
| 4829 | ML 239 |
| Breast cancer stem cell inhibitor | |
| 5153 | ML 240 |
| ATP-competitive inhibitor of p97 ATPase | |
| 4687 | ML 252 |
| Potent and selective KV7.2 inhibitor; brain penetrant | |
| 4777 | ML 277 |
| Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current | |
| 4880 | ML 281 |
| STK33 inhibitor | |
| 5380 | ML 297 |
| Selective Kir3.1/3.2 (GIRK1/2) channel activator | |
| 4894 | ML 299 |
| Potent inhibitor of PLD1 and PLD2; CNS penetrant | |
| 5733 | ML 311 |
| Inhibits Mcl-1-BIM interaction | |
| 5700 | ML 315 hydrochloride |
| Inhibitor of Clk and DYRK kinases | |
| 6435 | ML 323 |
| Potent and selective USP1-UAF1 allosteric inhibitor | |
| 5625 | ML 334 |
| Inhibitor of Keap1- Nrf2 interaction | |
| 6887 | ML 335 |
| Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator | |
| 4982 | ML 337 |
| Selective negative allosteric modulator of mGlu3 receptors | |
| 5943 | ML 339 |
| Potent and selective hCXCR6 antagonist | |
| 4586 | ML 3403 |
| p38 inhibitor | |
| 4945 | ML 347 |
| Potent and selective ALK1 and ALK2 inhibitor | |
| 5345 | ML 348 |
| Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor | |
| 5344 | ML 349 |
| Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor | |
| 6448 | ML 351 |
| Selective 12/15 LOX inhibitor; active in vivo | |
| 5387 | ML 354 |
| Selective PAR4 antagonist | |
| 5337 | ML 365 |
| Potent and selective K2P3.1 (TASK-1) channel blocker | |
| 5738 | ML 382 |
| MRGPRX1 positive allosteric modulator | |
| 6243 | ML 385 |
| Nrf2 inhibitor; phenotypically lethal | |
| 6888 | ML 402 |
| Selective TREK channel activator | |
| 6889 | ML 418 |
| Kir 7.1 inhibitor; also inhibits Kir 6.2 | |
| 6886 | ML 67-33 |
| K2P2.1 (TREK-1), K2P10.1 (TREK-2) and K2P4.1 (TRAAK) channel activator | |
| 4310 | ML 7 hydrochloride |
| Selective inhibitor of myosin light chain kinase | |
| 0431 | ML 9 hydrochloride |
| Myosin light chain kinase inhibitor | |
| 4746 | ML SA1 |
| Activator of TRPML channels | |
| 1885 | MLCK inhibitor peptide 18 |
| Selective inhibitor of myosin light chain kinase | |
| 3345 | MLN 4760 |
| Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor | |
| 6499 | MLN 4924 |
| Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable | |
| 4582 | MLR 1023 |
| Selective allosteric activator of Lyn kinase | |
| 6171 | MLS 1547 |
| G protein-biased D2 partial agonist | |
| 5756 | MLi-2 |
| Potent and selective LRRK2 inhibitor | |
| 5307 | MM 102 |
| Potent WDR5/MLL interaction inhibitor | |
| 3822 | MM 11253 |
| RARγ-selective antagonist | |
| 5992 | MM 54 |
| Potent apelin antagonist | |
| 6858 | MMG 11 |
| TLR2 antagonist | |
| 3537 | MMK 1 |
| Potent and selective FPR2 agonist | |
| 4388 | MNI 137 |
| Selective negative allosteric modulator of group II mGlu receptors | |
| 1490 | MNI-caged-L-glutamate |
| Stable photoreleaser of L-glutamate | |
| 6871 | MO-I-500 |
| FTO inhibitor; anticonvulsant | |
| 2568 | MOG (35-55) |
| Encephalitogenic myelin oligodendrocyte glycoprotein fragment | |
| 5770 | MONNA |
| Potent TMEM16A (Anoctamin-1) blocker | |
| 5803 | MP A08 |
| Selective ATP competitive SphK1 and 2 inhibitor; cell permeable | |
| 5231 | MPC 6827 hydrochloride |
| Inhibitor of microtubule polymerization; antimitotic and antitumor | |
| 1212 | MPEP hydrochloride |
| Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors | |
| 1991 | MPP dihydrochloride |
| Highly selective ERα antagonist | |
| 7695 | Mpro 61 |
| Potent non-covalent inhibitor of SARS-CoV-2 main protease | |
| 7230 | MPro N3 |
| Coronavirus Mpro inhibitor | |
| 3817 | MRK 016 |
| α5-selective GABAA inverse agonist | |
| 4000 | MRK 560 |
| γ-secretase inhibitor; attenuates amyloid plaque deposition | |
| 6803 | MRK 740 |
| Potent PRDM9 inhibitor | |
| 1217 | MRS 1220 |
| Highly potent and selective hA3 antagonist | |
| 1385 | MRS 1334 |
| Potent, highly selective hA3 antagonist | |
| 1584 | MRS 1706 |
| Potent and selective A2B inverse agonist | |
| 2752 | MRS 1754 |
| Selective A2B antagonist | |
| 0900 | MRS 2179 tetrasodium salt |
| Selective P2Y1 antagonist | |
| 2402 | MRS 2211 |
| Competitive P2Y13 antagonist | |
| 2158 | MRS 2279 |
| Selective, high affinity P2Y1 antagonist | |
| 2157 | MRS 2365 |
| Highly potent and selective P2Y1 agonist | |
| 2159 | MRS 2500 tetraammonium salt |
| Highly potent and selective P2Y1 antagonist | |
| 2146 | MRS 2578 |
| Selective P2Y6 antagonist | |
| 2915 | MRS 2690 |
| Potent P2Y14 agonist | |
| 2502 | MRS 2693 trisodium salt |
| Selective P2Y6 agonist | |
| 3884 | MRS 2768 tetrasodium salt |
| Selective P2Y2 agonist | |
| 5633 | MRS 2905 |
| Potent and selective P2Y14 receptor agonist | |
| 4260 | MRS 2957 triethylammonium salt |
| Potent and selective P2Y6 agonist | |
| 4261 | MRS 4062 triethylammonium salt |
| Selective P2Y4 receptor agonist | |
| 5428 | MRS 5698 |
| High affinity and selective A3 agonist | |
| 5134 | MRT 67307 dihydrochloride |
| Salt inducible kinase (SIK) inhibitor | |
| 5067 | MRT 68601 hydrochloride |
| Potent TBK inhibitor | |
| 5780 | MRT 68921 dihydrochloride |
| ULK inhibitor | |
| 7488 | MRTX 849 |
| Mutation-selective inhibitor of KRASG12C | |
| 5713 | MS 023 dihydrochloride |
| Potent and selective type I PRMT inhibitor | |
| 6299 | MS 15203 |
| Potent and selective GPR171 partial agonist | |
| 7395 | MS 154 |
| Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR | |
| 7396 | MS 154N |
| Negative control for MS 154 (Cat No. 7395) | |
| 6298 | MS 21570 |
| GPR171 antagonist | |
| 6208 | MS 275 |
| HDAC (Class I) inhibitor | |
| 7397 | MS 39 |
| Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR | |
| 7398 | MS 39N |
| Negative control for MS 39 (Cat. No. 7397) | |
| 5173 | MS 436 |
| Potent and selective BRD4(1) inhibitor | |
| 7353 | MSA 2 |
| Non-nucleotide STING agonist; orally bioavailable | |
| 5641 | MSC 2032964A |
| Potent and selective ASK1 inhibitor; orally bioavailable | |
| 5954 | MSG 606 |
| Potent human MC1 receptor antagonist; also MC3 and MC5 partial agonist | |
| 3013 | [Nle4,D-Phe7]-α-MSH |
| Melanocortin receptor agonist | |
| 2584 | α-MSH |
| Endogenous melanocortin receptor agonist | |
| 0803 | MSOP |
| Specific group III mGlu antagonist | |
| 2921 | MTEP hydrochloride |
| Potent and selective mGlu5 antagonist | |
| 5224 | MTT |
| Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry | |
| 6154 | MZ 1 |
| (+)-JQ1 based Degrader (PROTAC®) that selectively degrades BRD4 | |
| 7681 | Mandi |
| Highly efficient chemical inducer of proximity (CIP) | |
| 6856 | α-Mangostin |
| Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines | |
| 3756 | Maraviroc |
| Selective CCR5 antagonist | |
| 3563 | Margatoxin |
| Potent KV1.3 channel blocker | |
| 2631 | Marimastat |
| Broad spectrum MMP inhibitor | |
| 7705 | Masitinib New |
| Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor | |
| 1192 | Mastoparan |
| Activates Gi and Go | |
| 4949 | MaxiPost |
| Potassium channel modulator; exerts subtype-specific effects | |
| 1384 | McN-A 343 |
| Selective M1 muscarinic agonist | |
| 3982 | Mdivi 1 |
| Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis | |
| 3873 | MeBIO |
| Inactive analog of BIO (Cat. No. 3194) | |
| 2281 | 2'-MeCCPA |
| Highly selective and potent A1 receptor agonist | |
| 2843 | Mecamylamine hydrochloride |
| Non-competitive nAChR antagonist | |
| 4245 | Meclizine dihydrochloride |
| Human pregnane X receptor agonist; H1 antagonist | |
| 5160 | Medetomidine hydrochloride |
| Potent and highly selective α2 agonist | |
| 6819 | Mefloquine hydrochloride |
| Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal | |
| 6285 | Megestrol Acetate |
| Synthetic progesterone analog | |
| 2566 | Melanotan II |
| High affinity melanocortin receptor agonist | |
| 3550 | Melatonin |
| Endogenous hormone; agonist at MT1 and MT2 | |
| 1193 | Melittin |
| Inhibits Gs and stimulates Gi activity | |
| 4619 | Melphalan |
| DNA alkylating agent; cytotoxic and antineoplastic | |
| 0773 | Memantine hydrochloride |
| NMDA antagonist; acts at ion channel site | |
| 0660 | Mepyramine maleate |
| Selective H1 inverse agonist | |
| 7577 | 3-Mercaptopicolinic acid hydrochloride New |
| Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis | |
| 4103 | 6-Mercaptopurine |
| Purine analog; inhibits DNA and RNA synthesis | |
| 3053 | Mesopram |
| Orally active PDE4 inhibitor | |
| 1644 | Mesulergine hydrochloride |
| 5-HT2A and 5-HT2C antagonist; also D2-like partial agonist | |
| 1443 | Metastin (human) |
| Potent, endogenous ligand for kisspeptin receptor | |
| 0590 | Metergoline |
| 5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7 | |
| 2864 | Metformin hydrochloride |
| Activator of LKB1/AMPK; antidiabetic agent | |
| 1230 | Methotrexate |
| Cytotoxic agent | |
| 4920 | Methoxy-X04 |
| Fluorescent amyloid β detector; brain penetrant | |
| 7320 | Methoxyluteolin |
| Inhibitor of pro-inflammatory mediator release from mast cells | |
| 3513 | N2-Methyl-L-arginine |
| Lysosomal system c L-arginine uptake inhibitor | |
| 5698 | 1-Methyl-D-tryptophan |
| Indoleamine 2,3-dioxygenase (IDO) inhibitor | |
| 3977 | 3-Methyladenine |
| Class III PI 3-kinase inhibitor; also inhibits autophagy | |
| 3213 | Methylene Blue |
| Biological stain; also neuroprotective and antimalarial | |
| 3209 | α,β-Methyleneadenosine 5'-triphosphate trisodium salt |
| Non-selective P2 agonist | |
| 0549 | Methylergometrine maleate |
| Active metabolite of methysergide (Cat. No. 1064) | |
| 0569 | (R)-(-)-α-Methylhistamine dihydrobromide |
| Potent, standard H3 agonist | |
| 2342 | 4-Methylhistamine dihydrochloride |
| Selective, high affinity H4 agonist | |
| 1029 | Methyllycaconitine citrate |
| Selective α7 neuronal nAChR antagonist | |
| 4979 | Methylmalonate |
| Succinate dehydrogenase inhibitor | |
| 6109 | Methylnaltrexone bromide |
| μ antagonist; peripherally restricted | |
| 1812 | Threo-methylphenidate hydrochloride |
| Inhibitor of dopamine and noradrenalin transporters. Psychomotor stimulant | |
| 4819 | Methylprednisolone |
| Glucocorticoid receptor agonist | |
| 3017 | 1-Methylpsilocin |
| Potent and selective 5-HT2C agonist | |
| 1624 | 2-Methylthioadenosine diphosphate trisodium salt |
| Potent agonist at P2Y1, P2Y12 and P2Y13 | |
| 1062 | 2-Methylthioadenosine triphosphate tetrasodium salt |
| Non-selective P2 agonist | |
| 1064 | Methysergide maleate |
| 5-HT1/5-HT2 antagonist | |
| 3256 | Metoprolol tartrate |
| Selective β1 antagonist | |
| 3292 | Metyrapone |
| 11-β hydroxylase inhibitor | |
| 1526 | Mevastatin |
| HMG-CoA reductase inhibitor | |
| 2596 | Mexiletine hydrochloride |
| Na+ channel blocker; antiarrhythmic agent | |
| 0997 | Mianserin hydrochloride |
| 5-HT2 antagonist. Has moderate affinity for 5-HT6 | |
| 2198 | Mibefradil dihydrochloride |
| CaV3.x blocker | |
| 3016 | Miconazole nitrate |
| Azole antifungal agent | |
| 2832 | Midazolam hydrochloride |
| Benzodiazepine agonist | |
| 1479 | Mifepristone |
| Progesterone and glucocorticoid receptor antagonist | |
| 4985 | Miglitol |
| α-glucosidase inhibitor | |
| 3117 | Miglustat hydrochloride |
| α-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity | |
| 3286 | Milnacipran hydrochloride |
| 5-HT and NA reuptake inhibitor (SNRI) | |
| 1504 | Milrinone |
| PDE3 inhibitor | |
| 3268 | Minocycline hydrochloride |
| Antibiotic. Displays neuroprotective effects | |
| 0583 | Minoxidil |
| Kir6 channel (KATP) opener | |
| 7070 | Mirabegron |
| Potent and selective β3 agonist | |
| 3190 | Mirin |
| MRN-ATM pathway inhibitor | |
| 7091 | Miro1 Reducer |
| Promotes mitochondrial Rho GTPase 1 (Miro1) degradation | |
| 2018 | Mirtazapine |
| Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant | |
| 2297 | Misoprostol |
| Cytoprotective PGE1 analog | |
| 1489 | Mithramycin A |
| Inhibitor of DNA and RNA polymerase | |
| 7641 | Mito-HE |
| Fluorescent mitochondrial superoxide indicator in live cells | |
| 7700 | MitoBrilliant™ 646 New |
| Universal red fluorescent mitochondrial stain for both live and fixed cells | |
| 7693 | MitoBrilliant™ Live 549 New |
| Orange fluorescent mitochondrial stain for live cells, Δψm dependent | |
| 7417 | MitoBrilliant™ Live 646 New |
| Red fluorescent mitochondrial stain for live cells, Δψm dependent | |
| 6444 | MitoMark Green I |
| Green fluorescent mitochondrial stain; cell permeable | |
| 6445 | MitoMark Red I |
| Red fluorescent mitochondrial stain; cell permeable | |
| 4428 | MitoPY1 |
| Fluorescent mitochondrial hydrogen peroxide indicator | |
| 6898 | Mitochondrial fusion promoter M1 |
| Mitochondrial fusion promoter | |
| 3258 | Mitomycin C |
| DNA cross-linking antitumor agent | |
| 4250 | Mitoxantrone dihydrochloride |
| Topoisomerase II inhibitor; immunosuppressive and antineoplastic agent | |
| 4395 | Moclobemide |
| Reversible MAO-A inhibitor | |
| 1811 | Modafinil |
| Psychostimulant | |
| 7586 | Molnupiravir |
| Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection | |
| 1305 | Monastrol |
| Selective inhibitor of mitotic kinesin Eg5 | |
| 5904 | Montelukast sodium |
| CysLT1 and GPR17 antagonist | |
| 5158 | Morphine hydrochloride |
| Narcotic opioid analgesic | |
| 2264 | Motilin (human, porcine) |
| Endogenous peptide regulator of gastrointestinal motility | |
| 7853 | Mpro 13b-H New |
| Negative control for Mpro 13b-K (Cat. No. 7228) | |
| 7228 | Mpro 13b-K |
| Coronavirus Mpro inhibitor | |
| 5142 | Mps1-IN-1 dihydrochloride |
| Selective Mps1 kinase inhibitor | |
| 3816 | Muristerone A |
| Stimulates Bcl-XL mRNA transcription; antiapoptotic | |
| 3074 | (+)-Muscarine iodide |
| Muscarinic receptor agonist | |
| 0289 | Muscimol |
| Potent GABAA agonist; also GABAA-ρ partial agonist | |
| 4102 | Mycophenolate mofetil |
| Inosine monophosphate dehydrogenase (IMPDH) inhibitor | |
| 1505 | Mycophenolic acid |
| Inosine monophosphatase dehydrogenase (IMPDH) inhibitor | |
| 3399 | Myelin Basic Protein (87-99) |
| Major antigenic component implicated in the pathophysiology of multiple sclerosis |
Tocris Products by Catalog Number
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