Cat. No. | Product Name / Activity |
---|---|
5550 | E 2012 |
γ-secretase modulator; Notch-sparing | |
5208 | E 64 |
Potent and irreversible cysteine protease inhibitor | |
4545 | E 64d |
Cathepsin inhibitor; interferes with autolysosomal digestion | |
6785 | E 7820 |
α2 integrin inhibitor; anti-angiogenic | |
1808 | E-4031 dihydrochloride |
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr) | |
3993 | EB 1089 |
Vitamin D receptor (VDR) agonist | |
4140 | EB 47 |
Potent PARP-1 inhibitor | |
1041 | 1-EBIO |
Epithelial KCa channel activator | |
4701 | EC 144 |
High affinity, potent and selective Hsp90 inhibitor | |
5849 | EC 19 |
Synthetic retinoid; induces differentiation of stem cells | |
4011 | EC 23 |
Synthetic retinoid; induces differentiation of stem cells | |
2811 | EDTA |
Chelating agent | |
6986 | EG 00229 trifluoroacetate |
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1 | |
4524 | EGCG |
β-secretase (BACE) inhibitor; inhibits amyloid assembly | |
2807 | EGTA |
Calcium chelating agent | |
1261 | EHNA hydrochloride |
Adenosine deaminase inhibitor | |
3872 | EHT 1864 |
Potent Rac family inhibitor | |
6248 | EHop 016 |
Rac inhibitor | |
7231 | EIDD 1931 New |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide | |
3378 | EIPA |
Inhibits TRPP3-mediated currents; also inhibits the Na+/H+ exchanger (NHE) | |
6292 | ELARR>GG |
Negative control for ELA-32 (Cat.No.6291) | |
6698 | ELA-11 (human) |
High affinity apelin agonist | |
6293 | ELA-14 (human) |
Potent apelin agonist; bioactive fragment of ELA-32 (Cat. No. 6291) | |
6294 | ELA-14 negative control |
Negative control for ELA-14 (Cat.No.6293) | |
6697 | ELA-21 (human) |
High affinity apelin agonist | |
6291 | ELA-32 (human) |
Potent and high affinity apelin agonist; stimulates angiogenesis | |
4470 | EMD 281014 hydrochloride |
Selective 5-HT2A antagonist | |
2382 | EMD 386088 hydrochloride |
Potent 5-HT6 agonist | |
1849 | EMD 66684 |
Potent and selective non-peptide AT1 antagonist | |
5646 | EML 425 |
Reversible and non-competitive CBP/p300 inhibitor | |
4558 | EMPA |
Highly potent and selective OX2 antagonist; brain penetrant | |
3576 | (±)-5'-Chloro-5'-deoxy-ENBA |
Highly selective A1 agonist | |
2908 | EO 1428 |
Selective inhibitor of p38α and p38β2 | |
4518 | EPPTB |
Trace amine 1 (TA1) receptor antagonist; also displays inverse agonism | |
5567 | EPZ 004777 |
Highly potent DOT1L inhibitor | |
6516 | EPZ 015666 |
Potent and selective PRMT5 inhibitor | |
2471 | ER 27319 maleate |
Selective Syk kinase inhibitor | |
3823 | ER 50891 |
Selective RARα antagonist | |
5924 | ER 819762 |
Potent EP4 receptor antagonist; orally bioavailable | |
4276 | ERB 041 |
Potent ERβ agonist | |
6632 | ERGi-USU |
Rio2 kinase (RIOK2) inhibitor; inhibits ERG protein | |
5393 | ERK5-IN-1 |
Potent and selective ERK5 inhibitor | |
6320 | ESI 05 |
Epac2 inhibitor | |
4773 | ESI 09 |
Epac inhibitor | |
4702 | ETP 45658 |
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR | |
5183 | ETP 45835 dihydrochloride |
Mnk1 and Mnk2 inhibitor | |
2780 | EX 527 |
Selective SIRT1 inhibitor | |
5728 | EXP 3174 |
Potent and selective AT1 antagonist | |
4876 | Eact |
Activator of Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) | |
5245 | Ebselen |
Glutathione peroxidase mimic; peroxynitrite scavenger | |
6832 | Ec2la |
Positive allosteric modulator of CB2 receptors; active in vivo | |
5520 | Echinomycin |
Highly potent and selective HIF-1α inhibitor | |
3202 | Echistatin, α1 isoform |
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor | |
4784 | Edaglitazone |
Potent and selective PPARγ agonist; antidiabetic | |
0786 | Edaravone |
Anti-ischemic and antioxidant | |
3022 | Edelfosine |
Selective PI-PLC inhibitor, also PAF receptor agonist | |
3922 | Eeyarestatin I |
Potent inhibitor of ER-associated protein degradation and translocation | |
0792 | Efaroxan hydrochloride |
α2 antagonist and I1, I3 ligand | |
5695 | Eggmanone |
Potent and selective PDE4 inhibitor; suppresses hedgehog signaling | |
4646 | Elacridar hydrochloride |
P-gp inhibitor | |
1914 | Eledoisin |
Potent tachykinin receptor ligand | |
1920 | Eledoisin-Related Peptide |
Tachykinin receptor ligand | |
5316 | Elinogrel |
P2Y12 antagonist | |
2195 | Eliprodil |
Non-competitive and GluN2B-selective NMDA antagonist | |
3058 | Ellagic acid |
Selective inhibitor of CK2. Also inhibits glutathione S-transferase | |
3357 | Ellipticine |
Antitumor and intercalating agent; inhibits DNA topoisomerase II | |
2156 | Embelin |
Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor | |
3811 | Emodin |
Naturally occurring anthraquinone; displays anti-inflammatory, antitumor and neuroprotective activity | |
1055 | Endomorphin-1 |
Potent and selective μ agonist | |
1056 | Endomorphin-2 |
Potent and selective μ agonist | |
1160 | Endothelin 1 (human, porcine) |
Potent vasoconstrictor peptide | |
1164 | Endothelin 2 (human) |
ETA/ETB agonist | |
1162 | Endothelin 3 (human, rat) |
Potent vasoconstrictor | |
1197 | [Ala1,3,11,15]-Endothelin |
Selective ETB agonist | |
3705 | Endoxifen |
Potent antiestrogen; ERα ligand | |
1889 | [Leu5]-Enkephalin |
Endogenous opioid agonist peptide | |
1693 | Enoximone |
PDE3 inhibitor | |
4720 | Entacapone |
Potent COMT inhibitor; blocks α-synuclein aggregation | |
6234 | Entecavir |
Potent and selective hepatitis B virus inhibitor | |
5994 | Enzastaurin |
Potent PKCβ inhibitor | |
6102 | Ep23, 5'-DY647 |
High affinity fluorescently tagged aptamer for EpCam | |
0684 | (±)-Epibatidine |
High affinity nAChR agonist | |
6340 | Epiblastin A |
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal | |
3260 | Epirubicin hydrochloride |
Inhibits DNA synthesis and function. Inhibits DNA topoisomerase II | |
2397 | Eplerenone |
Selective mineralocorticoid receptor antagonist | |
4958 | Eplivanserin hemifumarate |
Potent and selective 5-HT2A antagonist | |
2989 | Epoprostenol |
Endogenous IP receptor agonist | |
3502 | Epothilone B |
Microtubule stabilization agent; promotes tubulin polymerization | |
4725 | Eptifibatide |
Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation | |
6158 | (S)-Equol |
Potent estrogen receptor β (ERβ) agonist; dihydrotestosterone antagonist | |
5449 | Erastin |
Mitochondrial VDAC modulator; also Ferroptosis activator | |
4146 | Ercalcidiol |
Metabolite of vitamin D2 | |
7199 | (±)-Eriodictyol New |
Potent TRPV1 antagonist; also antioxidant; activates Nrf2/ARE signaling | |
4796 | Escitalopram oxalate |
Selective serotonin reuptake inhibitor (SSRI) | |
2823 | α-Estradiol |
Endogenous estrogen receptor agonist | |
2824 | β-Estradiol |
Endogenous ER agonist | |
0438 | Etazolate hydrochloride |
PDE4 inhibitor | |
6204 | 7-Ethoxyresorufin |
Fluorometric CYP450 substrate | |
5950 | Ethyl LipotF New |
Selective FTO inhibitor | |
5712 | 4-Ethynyl-N-ethyl-1,8-naphthalimide |
Click-activated fluorescent probe | |
1847 | Eticlopride hydrochloride |
D2 and D3 antagonist (D3 > D2) | |
3113 | Etifoxine hydrochloride |
Ligand of the translocator protein (TSPO); also GABAA receptor potentiator | |
1471 | Etomidate |
GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors | |
4539 | (R)-(+)-Etomoxir sodium salt |
Carnitine palmitoyltransferase I (CPT1) inhibitor | |
1226 | Etoposide |
Topoisomerase II inhibitor | |
0845 | Evans Blue tetrasodium salt |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist | |
6188 | Everolimus |
mTOR inhibitor; Immunosuppressant | |
5833 | Ex 26 |
Potent and selective S1P1 receptor antagonist | |
3759 | Exemestane |
Steroidal aromatase (CYP19) inhibitor | |
2081 | Exendin-3 (9-39) amide |
Potent GLP-1 receptor antagonist | |
1933 | Exendin-4 |
Potent GLP-1 receptor agonist | |
1850 | Exo1 |
Inhibits Golgi-ER traffic; blocks exocytosis |