Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewAcridine Orange hydrochloride
Description: Nucleic acid binding dye
Chemical Name: N,N,N',N'-Tetramethyl-3,6-acridinediamine hydrochloride
Purity: ≥98% (HPLC)
Biological Activity for Acridine Orange hydrochloride
Acridine Orange hydrochloride is a cell and organelle membrane permeable nucleic acid binding dye. Emits green fluorescence when bound to double-stranded DNA and red fluorescence when bound to RNA or single-stranded DNA. Used in cell cycle and apoptosis studies and as a lysosomal dye.
This product is supplied as a hydrochloride salt, the stoichiometry of which is batch dependent. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content.
Technical Data for Acridine Orange hydrochloride
| M. Wt | 265.36 (Free Base) |
| Formula | C17H19N3.HCl |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| PubChem ID | 517204 |
| InChI Key | VSTHNGLPHBTRMB-UHFFFAOYSA-N |
| Smiles | CN(C)C1=CC=C2C(N=C(C=C(N(C)C)C=C3)C3=C2)=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Acridine Orange hydrochloride
| Solubility | Soluble to 10 mg/ml in water |
Product Datasheets for Acridine Orange hydrochloride
References for Acridine Orange hydrochloride
References are publications that support the biological activity of the product.
Kiyoshima et al (2013) Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression. PLoS ONE 8 80998 PMID: 24278362
McMaster et al (1977) Analysis of single and double stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange. Proc.Natl.Acad.Sci.USA 74 4835 PMID: 73185
Ratan et al (2008) Rapid communication: oxidative stress induces apoptosis in embryonic cortical neurons. J.Neurobiol. 62 376 PMID: 7903353
If you know of a relevant reference for Acridine Orange hydrochloride, please let us know.
View Related Products by Target
Keywords: Acridine Orange hydrochloride, Acridine Orange hydrochloride supplier, nucleic, acid, binding, dyes, cell, cycle, lysosomal, DNA, stains, RNA, 65612, 65-61-2, Fluorescent, Stains, Probes, Cell, Viability, and, Dyes, 5092, Tocris Bioscience
Citations for Acridine Orange hydrochloride
Citations are publications that use Tocris products.
Currently there are no citations for Acridine Orange hydrochloride. Do you know of a great paper that uses Acridine Orange hydrochloride from Tocris? Please let us know.
Reviews for Acridine Orange hydrochloride
There are currently no reviews for this product. Be the first to review Acridine Orange hydrochloride and earn rewards!
Have you used Acridine Orange hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals