You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent VPS34 inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin-induced autophagy (IC50 values = 40 and 90 nM, respectively).
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 346.73. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||14.42 mL||72.1 mL||144.2 mL|
|1 mM||2.88 mL||14.42 mL||28.84 mL|
|2 mM||1.44 mL||7.21 mL||14.42 mL|
|10 mM||0.29 mL||1.44 mL||2.88 mL|
References are publications that support the biological activity of the product.
Richters et al (2015) Identification and further development of potent TBK1 inhibitors. ACS Chem Biol. 10 289 PMID: 25540906
Robke et al (2017) Phenotypic identification of a novel autophagy inhibitor chemotype targeting lipid kinase VPS34. Angew.Chem.Int.Ed.Engl. 56 8153 PMID: 28544137
If you know of a relevant reference for Autophinib, please let us know.
View Related Products by Product Action
Keywords: Autophinib, Autophinib supplier, Potenet, autophagy, inhibitors, inhibits, VPS34, vacuolar, protein, sorting, 34, Autophagy, 6324, Tocris Bioscience
Citations for Autophinib
Citations are publications that use Tocris products.
Currently there are no citations for Autophinib. Do you know of a great paper that uses Autophinib from Tocris? Please let us know.
Reviews for Autophinib
There are currently no reviews for this product. Be the first to review Autophinib and earn rewards!
Have you used Autophinib?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Programmed Cell Death Poster
There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.