Atrial natriuretic factor (1-28) (human, porcine)

Pricing Availability   Qty
Description: Endogenous peptide regulating blood pressure
Alternative Names: Atrial Natriuretic Peptide (1-28) (human,porcine)
Purity: ≥95% (HPLC)
Reviews (1)

Biological Activity

Atrial natriuretic factor (1-28) (human, porcine) is an endogenous peptide produced by the heart; involved in blood pressure regulation. Produces natriuresis, diuresis and vasorelaxation in vivo.

Technical Data

M. Wt 3080.46
Formula C127H205N45O39S3

(Modifications: Disulfide bridge: 7-23)

Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 91917-63-4
PubChem ID 16129708
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Atlas et al (1985) Atrial natriuretic factor (auriculin): structure and biological effects. J.Clin.Hypertens. 1 187 PMID: 2941526

de Bold et al (1985) Atrial natriuretic factor: a hormone produced by the heart. Science 230 767 PMID: 2932797

Rubattu and Volpe (2001) The atrial natriuretic peptide: a changing view. J.Hypertens. 19 1923 PMID: 11677356

If you know of a relevant reference for Atrial natriuretic factor (1-28) (human, porcine), please let us know.

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Citations for Atrial natriuretic factor (1-28) (human, porcine)

Citations are publications that use Tocris products.

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NP investigation in vitro.
By Anonymous on 08/05/2018
Assay Type: In Vitro
Species: Human

Used in vitro to investigate different roles of NP family members.