DL-AP4

Pricing Availability Delivery Time Qty
Cat.No. 0101 - DL-AP4 | C4H10NO5P | CAS No. 20263-07-4
Description: Broad spectrum EAA antagonist
Chemical Name: DL-2-Amino-4-phosphonobutyric acid
Purity: ≥98% (HPLC)
Datasheet
Citations (3)
Reviews
Literature

Biological Activity

Broad spectrum EAA ligand.

D-isomer, L-isomer and Sodium Salt also available.

Technical Data

M. Wt 183.1
Formula C4H10NO5P
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 20263-07-4
PubChem ID 2207
InChI Key DDOQBQRIEWHWBT-UHFFFAOYSA-N
Smiles O=C(C(N)CCP(O)(O)=O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 18.31 100
1eq. NaOH 18.31 100
water 6.04 33
phosphate buffered saline 6.04 33

Preparing Stock Solutions

The following data is based on the product molecular weight 183.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.46 mL 27.31 mL 54.61 mL
5 mM 1.09 mL 5.46 mL 10.92 mL
10 mM 0.55 mL 2.73 mL 5.46 mL
50 mM 0.11 mL 0.55 mL 1.09 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Evans et al (1979) Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 67 591 PMID: 316343

Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024


If you know of a relevant reference for DL-AP4, please let us know.

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3 Citations for DL-AP4

Citations are publications that use Tocris products. Selected citations for DL-AP4 include:

Sekaran et al (2005) Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina. Curr Biol 15 1099 PMID: 15964274

Schmidt and Kofuji (2009) Functional and morphological differences among intrinsically photosensitive retinal ganglion cells. J Neurosci 29 476 PMID: 19144848

Schmidt and Kofuji (2011) Structure and function of bistratified intrinsically photosensitive retinal ganglion cells in the mouse. J Comp Neurol 519 1492 PMID: 21452206


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