Inhibitor of intestinal α-glucosidase (IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 645.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.55 mL||7.75 mL||15.5 mL|
|5 mM||0.31 mL||1.55 mL||3.1 mL|
|10 mM||0.15 mL||0.77 mL||1.55 mL|
|50 mM||0.03 mL||0.15 mL||0.31 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Krause et al (1982) Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase inhibitor acarbose (BAY g 5421). Digestion 23 232 PMID: 6754513
Balfour and McTavish (1993) Acarbose: an update of its pharmacology and therapeutic use in diabetes mellitus. Drugs 46 1025 PMID: 7510610
Oki et al (2000) Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol.Pharm.Bull. 23 1084 PMID: 10993209
If you know of a relevant reference for Acarbose, please let us know.
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Keywords: Glucosidase alpha inhibitors inhibits intestinal Glycosylases Carbohydrate Metabolism Bay-g5421 Bay-g 5421 Glycosylases
Citations for Acarbose
Citations are publications that use Tocris products.
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Literature in this Area
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