|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 100 mM in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 197.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.07 mL||25.36 mL||50.73 mL|
|5 mM||1.01 mL||5.07 mL||10.15 mL|
|10 mM||0.51 mL||2.54 mL||5.07 mL|
|50 mM||0.1 mL||0.51 mL||1.01 mL|
References are publications that support the products' biological activity.
Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378 PMID: 6145492
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024
Schulte et al (1994) Utilization of the resolved L-isomer fo 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 649 203 PMID: 7953634
If you know of a relevant reference for L-AP5, please let us know.
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Keywords: L-AP5, supplier, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGlu, Ionotropic, NMDA, Receptors, NMDA, Receptors, Tocris Bioscience
2 Citations for L-AP5
Citations are publications that use Tocris products. Selected citations for L-AP5 include:
Kinney (2005) GAT-3 transporters regulate inhibition in the neocortex. J Neurophysiol 94 4533 PMID: 16135550
Fernández-Monreal et al (2004) Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. J Biol Chem 279 50850 PMID: 15448144
Do you know of a great paper that uses L-AP5 from Tocris? If so please let us know.
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