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Displaying Products by Catalog Number (6400 - 6499)

Cat. No. Product Name / Activity
6400 Alsterpaullone
Potent cdk1 and cdk2 inhibitor; also inhibits GSK-3β and Lck
6405 PF 05180999
Potent and selective PDE2A inhibitor
6406 Hydroxystilbamidine bis(methanesulfonate)
Displays different fluorescence emission wavelenghts when bound to DNA compared to RNA
6407 Fendiline Hydrochloride
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
6409 A 1210477
Selective, high affinity Mcl-1 inhibitor; proapoptotic
6410 Tipifarnib
Potent farnesyltransferase inhibitor; orally bioavailable
6411 tBPC
Positive allosteric modulator of NPY Y4 receptor
6414 Rupintrivir
Potent and selective irreversible human rhinovirus 3Cpro inhibitor
6416 CM 11
Homo-PROTAC for self-degradation of pVHL30
6417 CMP 98
Negative Control for CM 11 (Cat. No. 6416)
6418 Janelia Fluor® 585, SE
Orange dye (Reactive group: NHS ester). Applications: super resolution microscopy, confocal, two-photon excitation and live cell imaging
6419 Janelia Fluor® 635, SE
Red dye (Reactive group: NHS ester). Applications: super resolution microscopy, confocal, flow and live cell imaging
6420 Janelia Fluor® 669, SE
Far red dye (Reactive group: NHS ester). Applications: super resolution microscopy e.g. dSTORM & STED, confocal and live cell imaging
6422 DREADD agonist 21 dihydrochloride
Potent muscarinic DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
6423 Pep 2-8
Potent PCSK9 inhibitor
6424 Sodium Cromoglicate
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
6425 PSEM 308 hydrochloride
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6426 PSEM 89S
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6427 Tafluprost
Very high affinity FP receptor agonist
6428 Carboprost tromethamine
Synthetic Prostaglandin F (Cat. No. 4214) analog
6429 ML 210
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
6430 Takinib
Potent and selective TAK1/MAP3K7 kinase inhibitor
6431 Phentolamine Mesylate
Adrenergic α receptor antagonist; antihypertensive
6433 GSK 1016790A
Potent TRPV4 agonist; active in vivo
6434 DFHO
RFP fluorophore mimic for imaging RNA in living cells; activated by binding Corn aptamers
6435 ML 323
Potent and selective USP1-UAF1 allosteric inhibitor
6436 CY 09
NLRP3 inhibitor; active in vivo
6438 BRD 6989
Cdk8 inhibitor; enhances IL-10 production
6439 JNJ 0966
Pro-MMP9 activation inhibitor
6440 PIK 93
Potent PI 3-Kγ, PI 3-Kα and PI 4-KIIIβ inhibitor
6442 Gentamicin sulfate
Aminoglycoside antibiotic
6443 IU1-47
Potent USP14 inhibitor
6444 MitoMark Green I
Green fluorescent mitochondrial stain; cell permeable
6445 MitoMark Red I
Red fluorescent mitochondrial stain; cell permeable
6448 ML 351
Selective 12/15 LOX inhibitor; active in vivo
6450 Cortagine
Potent and selective CRF1 agonist
6451 Pexacerfont
Potent and selective CRF1 antagonist; anxiolytic
6454 LY 2603618
Potent and selective Chk1 inhibitor
6456 Fluorescein Tyramide
Green fluorescent reagent widely used for signal amplification in IHC and FISH
6457 Cyanine 3 Tyramide
Orange fluorescent reagent widely used for signal amplification in IHC and FISH
6458 Cyanine 5 Tyramide
Red fluorescent reagent widely used for signal amplification in IHC and FISH
6461 PARPi-FL
Potent fluorescent PARP inhibitor; cell permeable
6462 VH 032, amine
Functionalized VHL ligand for PROTACs
6463 VH 032 amide-PEG3-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6464 VH 032 amide-PEG4-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6465 VH 032 amide-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6466 TC E3 5031
Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
6467 Thalidomide 4'-oxyacetamide-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6468 Thalidomide 4'-oxyacetamide-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6469 Thalidomide 4'-oxyacetamide-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6470 A 410099.1
High affinity XIAP antagonist; active in vivo
6471 A 410099.1, amine
Functionalized IAP ligand for PROTACs
6472 A 410099.1 amide-PEG3-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6473 A 410099.1 amide-PEG2-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6474 A 410099.1 amide-alkylC4-amine
IAP ligand with alkyl linker and terminal amine for onward chemistry
6475 SU 6656
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
6476 Compound E
γ-secretase inhibitor; induces neuronal differentiation
6477 SAHM1
Notch pathway inhibitor; prevents Notch complex assembly
6479 CU CPT 9a
Highly potent TLR8 inhibitor
6480 GSK 583
Potent RIPK2 inhibitor; orally bioavailable and cell permeable
6481 AP 14145 hydrochloride
KCa2 channel negative allosteric modulator
6482 XMU MP 1
Potent and selective MST1/2 inhibitor; orally bioavailable
6483 Isoginkgetin
Pre-mRNA splicing inhibitor; cell permeable
6484 Terbinafine hydrochloride
Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase
6486 Aprepitant
Potent long-acting hNK1 antagonist
6488 5(6)-SFX (Fluorescein), SE
Green fluorescent dye for the labeling of primary amines
6489 Ocean Blue, SE
Blue fluorescent dye; supplied as NHS ester
6490 GNE 2861
Group II PAK inhibitor; potently inhibits PAK4 and PAK 6
6491 YM 155
Survivin suppressor
6492 GSK'872
Potent and selective RIP3 kinase inhibitor
6493 A 317491 sodium salt
Selective, high affinity P2X3 and P2X2/3 receptor antagonist; antinociceptive
6494 Galangin
TRPC5 inhibitor; also induces autophagy
6495 AM 12
TRPC5 inhibitor

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