All Products

Displaying Products by Catalog Number (6400 - 6499)

Cat. No. Product Name / Activity
6400 Alsterpaullone
Potent CDK1 and CDK2 inhibitor; also inhibits GSK-3β and Lck
6405 PF 05180999
Potent and selective PDE2A inhibitor
6407 Fendiline Hydrochloride
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
6409 A 1210477
Selective, high affinity Mcl-1 inhibitor; proapoptotic
6410 Tipifarnib
Potent farnesyltransferase inhibitor; orally bioavailable
6411 tBPC
Positive allosteric modulator of NPY Y4 receptor
6416 CM 11
Homo-PROTAC® for self-degradation of pVHL30
6418 Janelia Fluor® 585, SE
Orange dye (Reactive group: NHS ester). Applications: super resolution microscopy, confocal, two-photon excitation and live cell imaging
6419 Janelia Fluor® 635, SE
Red dye (Reactive group: NHS ester). Applications: super resolution microscopy, confocal, flow and live cell imaging
6420 Janelia Fluor® 669, SE
Far red dye (Reactive group: NHS ester). Applications: super resolution microscopy e.g. dSTORM & STED, confocal and live cell imaging
6422 DREADD agonist 21 dihydrochloride
Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
6423 Pep 2-8
Potent PCSK9 inhibitor
6424 Sodium Cromoglicate
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
6425 PSEM 308 hydrochloride
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6426 PSEM 89S
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6429 ML 210
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
6430 Takinib
Potent and selective TAK1/MAP3K7 kinase inhibitor
6431 Phentolamine Mesylate
Adrenergic α receptor antagonist; antihypertensive
6433 GSK 1016790A
Potent TRPV4 agonist; active in vivo
6434 DFHO
RFP fluorophore mimic for imaging RNA in living cells; activated by binding Corn aptamers
6435 ML 323
Potent and selective USP1-UAF1 allosteric inhibitor
6436 CY 09
NLRP3 inhibitor; active in vivo
6438 BRD 6989
Cdk8 inhibitor; enhances IL-10 production
6439 JNJ 0966
Pro-MMP9 activation inhibitor
6440 PIK 93
Potent PI 3-Kγ, PI 3-Kα and PI 4-KIIIβ inhibitor
6442 Gentamicin sulfate
Aminoglycoside antibiotic
6443 IU1-47
Potent USP14 inhibitor
6444 MitoMark Green I
Green fluorescent mitochondrial stain; cell permeable
6445 MitoMark Red I
Red fluorescent mitochondrial stain; cell permeable
6448 ML 351
Selective 12/15 LOX inhibitor; active in vivo
6451 Pexacerfont
Potent and selective CRF1 antagonist; anxiolytic
6454 LY 2603618
Potent and selective Chk1 inhibitor
6456 Fluorescein Tyramide
Green fluorescent reagent widely used for signal amplification in IHC and FISH
6457 Cyanine 3 Tyramide
Orange fluorescent reagent widely used for signal amplification in IHC and FISH
6458 Cyanine 5 Tyramide
Red fluorescent reagent widely used for signal amplification in IHC and FISH
6460 ABX 464
HIV RNA splicing modulator
6461 PARPi-FL
Potent fluorescent PARP inhibitor; cell permeable
6462 VH 032, amine
Functionalized VHL ligand for PROTACs
6463 VH 032 amide-PEG3-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6464 VH 032 amide-PEG4-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6465 VH 032 amide-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6466 Thalidomide-4-hydroxyacetate
Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs
6467 Thalidomide 4'-oxyacetamide-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6468 Thalidomide 4'-oxyacetamide-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6469 Thalidomide 4'-oxyacetamide-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6470 A 410099.1
High affinity XIAP antagonist; active in vivo
6471 A 410099.1, amine
Functionalized IAP ligand for PROTACs
6472 A 410099.1 amide-PEG3-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6473 A 410099.1 amide-PEG2-amine
IAP ligand with PEG linker and terminal amine for onward chemistry
6474 A 410099.1 amide-alkylC4-amine
IAP ligand with alkyl linker and terminal amine for onward chemistry
6475 SU 6656
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
6476 Compound E
γ-secretase inhibitor; induces neuronal differentiation
6477 SAHM1
Notch pathway inhibitor; prevents Notch complex assembly
6479 CU CPT 9a
Highly potent TLR8 inhibitor
6480 GSK 583
Potent RIPK2 inhibitor; orally bioavailable and cell permeable
6481 AP 14145 hydrochloride
Negative allosteric modulator of KCa2 (SK) channels
6482 XMU MP 1
Potent and selective MST1/2 inhibitor; orally bioavailable
6483 Isoginkgetin
Pre-mRNA splicing inhibitor; cell permeable
6484 Terbinafine hydrochloride
Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase
6486 Aprepitant
Potent long-acting hNK1 antagonist
6489 Ocean Blue, SE
Blue fluorescent dye; supplied as NHS ester
6490 GNE 2861
Group II PAK inhibitor; potently inhibits PAK4 and PAK 6
6491 YM 155
Survivin suppressor
6492 GSK'872
Potent and selective RIP3 kinase inhibitor
6493 A 317491 sodium salt
Selective, high affinity P2X3 and P2X2/3 antagonist; antinociceptive
6494 Galangin
TRPC5 inhibitor; also induces autophagy
6495 AM 12
TRPC5 inhibitor
6497 GSK 2833503A
Potent and selective TRPC6 and TRPC3 antagonist
6498 TASP 0277308
Potent and selective S1P1 receptor antagonist; inhibits angiogenesis
6499 MLN 4924
Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable

Tocris Products Alphabetically by Name