All Products

Displaying Products Alphabetically by Name (P)

Cat. No. Product Name / Activity
4485 P 22077
USP7 inhibitor
5760 P-3FAX-Neu5Ac
Sialic acid analog; sialyltransferase inhibitor
4733 P005091
USP7 inhibitor
5127 P1
Protein disulfide isomerase (PDI) inhibitor
1355 P1075
Potent Kir6 (KATP) channel opener
4744 P11
Potent antagonist of αvβ3-vitronectin interaction; antiangiogenic
6897 P110
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable
6073 P21d hydrochloride
Potent and selective Brk inhibitor
4076 P7C3
NAMPT activator; also proneurogenic and neuroprotective
5463 PA 1 dihydrochloride
Photoswitchable ENaC blocker
5086 PA 452
RXR antagonist
6657 PA 8
PAC1 receptor antagonist
6149 PA Janelia Fluor® 549, SE
Yellow photoactivatable dye (Reactive group: NHS ester). Applications: super resolution microscopy (PALM), single molecule tracking and live cell imaging
6150 PA Janelia Fluor® 646, SE
Red photoactivatable dye (Reactive group: NHS ester). Applications: super resolution microscopy (PALM), single molecule tracking and live cell imaging
6700 PA Nic
Caged nicotine; photoactivated by one-photon and two-photon excitation
2681 17-PA
Antagonist of neurosteroid potentiation and direct gating of GABAA
2581 PAC 1
Activator of procaspase-3; pro-apoptotic
1183 PACAP 1-27
Potent stimulator of adenylyl cyclase
1186 PACAP 1-38
Potent stimulator of adenylyl cyclase
3236 PACAP 6-38
Potent PAC1 receptor antagonist
5116 PACMA 31
Irreversible protein disulfide isomerase (PDI) inhibitor
1460 PACOCF3
Phospholipase A2 inhibitor
2940 PAF (C16)
Endogenous platelet-activating factor (PAF)
2203 PALDA
Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors
6551 PAMP-12 (human, porcine)
Potent MRGPRX2 agonist
6552 PAMP-20 (human)
MRGPRX2 agonist; also non-competitive nAChR antagonist
5041 PAOPA
Allosteric modulator of D2 receptors
6461 PARPi-FL
Potent fluorescent PARP inhibitor; cell permeable
2562 PB 28 dihydrochloride
High affinity σ2 agonist
5930 PBIT
JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor
4611 PBP 10
Selective FPR2 antagonist; cell permeable
5564 PBS, 100 Tablets
PBS Tablets
0571 PCA 4248
PAF receptor antagonist
5012 PCI 29732
Potent BTK inhibitor
4643 PCI 34051
Potent and selective HDAC8 inhibitor
5419 PCNA I1
PCNA inhibitor
4192 PD 0325901
Potent inhibitor of MEK1/2
4786 PD 0332991 isethionate
Potent cdk4 and cdk6 inhibitor; brain penetrant
1671 PD 102807
Selective M4 antagonist
2830 PD 118057
Selective KV11.1 (hERG) channel activator
1361 PD 123319 ditrifluoroacetate
Potent and selective non-peptide AT2 antagonist
1243 (+)-PD 128907 hydrochloride
High affinity D3 agonist (D3 ≥ D2 > D4)
2608 PD 135158
Potent and selective CCK2 antagonist
2606 PD 144418 oxalate
High affinity, selective σ1 ligand
2850 PD 146176
Selective 15-lipoxygenase inhibitor
1269 PD 150606
Cell permeable calpain inhibitor
1037 PD 153035 hydrochloride
EGFR-kinase inhibitor
2615 PD 158780
Potent ErbB receptor family inhibitor
3724 PD 161570
Selective FGFR inhibitor
3785 PD 166285 dihydrochloride
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
2520 PD 166793
Broad spectrum MMP inhibitor
1065 PD 168077 maleate
High affinity, selective D4 agonist
3529 PD 168568 dihydrochloride
Potent and selective D4 antagonist
3044 PD 173074
FGFR1 and -3 inhibitor
3552 PD 173212
Potent CaV2.2 blocker
2602 PD 176252
GRP (BB2) and NMB (BB1) receptor antagonist
4965 PD 180970
p210Bcr/Abl kinase inhibitor; also inhibits c-Src and KIT
4237 PD 184352
Selective MEK inhibitor
2605 PD 198306
Selective inhibitor of MEK1/2
4824 PD 334581
MEK1 inhibitor
5124 PD 404182
High affinity inhibitor of KDO 8-P synthase; also DDAH1 inhibitor
2694 PD 407824
Potent and selective inhibitor of Chk1 and Wee1
1363 PD 81723
Allosteric potentiator of A1 receptors
5101 PD 90780
Inhibits NGF binding to p75NTR
1213 PD 98059
MEK inhibitor
0298 L-trans-2,4-PDC
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
7007 PDD 00017238
High affinity and potent PARG inhibitor
7006 PDD 00017272
Potent PARG inhibitor
5952 PDD 00017273
Potent and selective PARG inhibitor; cell permeable
7009 PDD 00031705
Negative control for PDD 00017238 (Cat. No. 7007)
5210 PDP-EA
FAAH activator
2207 PDZ1 Domain inhibitor peptide
Disrupts interaction between GluK2 and PSD-95 PDZ1 domain
4086 PE 154
Targets and labels beta -amyloid plaques in histochemical analysis
5018 PEAQX tetrasodium salt
Potent and GluN2A-selective NMDA antagonist
6307 PEN (human)
GPR83 agonist
6308 PEN (mouse)
GPR83 agonist
6309 PEN (rat)
GPR83 agonist
4054 PEP 005
Protein kinase C activator
1758 PETCM
Activator of caspase-3
4821 PF 03814735
Aurora kinase A and B inhibitor
4239 PF 04217903 mesylate
Highly selective MET inhibitor
4818 PF 04418948
Potent and selective EP2 receptor antagonist
5915 PF 04449613
Potent PDE9 inhibitor; brain penetrant
6538 PF 04449913 maleate
Potent Smo antagonist
6374 PF 04457845
Potent and selective irreversible FAAH inhibitor
5755 PF 04479745
Potent and selective 5-HT2C agonist
5863 PF 04620110
Potent and selective DGAT-1 inhibitor; orally bioavailable
6347 PF 04628935
Potent ghrelin receptor inverse agonist
6024 PF 04671536 hydrochloride
Potent and selective PDE8B/8A inhibitor
4820 PF 04691502
Potent and selective dual PI 3-K/mTOR inhibitor
4916 PF 04885614
Potent and selective NaV1.8 channel blocker; active in vivo
6049 PF 04937319
Glucokinase partial activator
6345 PF 04991532
Potent hepatoselective glucokinase activator
5931 PF 05089771
Potent and selective Nav1.7 channel blocker
6003 PF 05105679
Selective TRPM8 blocker
5790 PF 05175157
Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
6405 PF 05180999
Potent and selective PDE2A inhibitor
6350 PF 05190457
High affinity and selective ghrelin receptor inverse agonist
4823 PF 05212384
Potent and selective dual PI 3-K/mTOR inhibitor
5752 PF 06260933 dihydrochloride
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK
6115 PF 06273340
Potent and selective pan-Trk inhibitor; peripherally restricted
6004 PF 06281355
Selective myeloperoxidase (MPO) inhibitor
6114 PF 06409577
Potent and selective allosteric activator of AMPK
6348 PF 06424439
Potent and selective DGAT2 inhibitor
4710 PF 06465469
Potent ITK inhibitor; also inhibits BTK
6373 PF 06650833
Potent and selective IRAK4 inhibitor
6506 PF 06551600 malonate
Potent and selective JAK3 inhibitor
6169 PF 06726304 acetate
Highly potent and SAM-competitive EZH2 inhibitor
4238 PF 184
Potent and selective IKKβ inhibitor
5751 PF 3084014 hydrobromide
Potent γ-secretase inhibitor
4279 PF 3644022
Potent MK2 inhibitor
4191 PF 3716556
Selective H+,K+-ATPase inhibitor
6005 PF 3758309 dihydrochloride
Potent PAK4 inhibitor; orally available
4175 PF 3845
Selective FAAH inhibitor
3354 PF 429242 dihydrochloride
Competitive inhibitor of SREBP site 1 protease
4278 PF 431396
Dual FAK/PYK2 inhibitor
4032 PF 4708671
S6K1 inhibitor
4277 PF 477736
Selective Chk1 inhibitor
4281 PF 4800567 hydrochloride
Selective casein kinase 1ε inhibitor
4252 PF 4981517
Selective CYP3A4 inhibitor
6346 PF 5006739
Potent CK1δ/ε inhibitor
3676 PF 514273
High affinity and selective CB1 antagonist
5262 PF 5274857 hydrochloride
High affinity and selective Smoothened (Smo) receptor antagonist
5754 PF 543 hydrochloride
Potent and selective SphK1 inhibitor
3239 PF 573228
Potent and selective FAK inhibitor
5939 PF 6274484
High affinity and potent covalent EGFR kinase inhibitor
3316 PF 670462
Potent and selective CK1ε and CK1δ inhibitor
3307 PF 750
Selective FAAH inhibitor
4078 PF 8380
Potent autotaxin inhibitor
3291 PF 915275
Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor
5917 PF 9184
Potent microsomal prostaglandin E synthase 1 (mPGES-1) inhibitor
4419 PF 945863
Macrolide antibiotic
3923 PF 998425
Non-steroidal androgen receptor antagonist
5801 PF CBP1
Selective CBP/p300 bromodomain inhibitor
4074 PF9 tetrasodium salt
Potent GPR17 agonist
4445 PFI 1
BET bromodomain inhibitor
4892 (R)-PFI 2 hydrochloride
Potent and selective SETD7 inhibitor
5400 (S)-PFI 2 hydrochloride
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
5072 PFI 3
Potent and selective SMARCA2/4 and polybromo 1 inhibitor
5576 PFI 4
Potent and selective BRPF1B bromodomain inhibitor
5339 PFK 15
Selective PFKFB3 inhibitor
6222 PFM 01
MRE11 endonuclease inhibitor
3943 PG 01
CFTR potentiator; corrects F508del-CFTR conductance defect
3887 PG 01037 dihydrochloride
Selective D3 antagonist
4919 PG 106
Selective MC3 receptor antagonist
5094 PG 931
Potent and selective MC4 receptor agonist
0750 PG-9 maleate
Presynaptic cholinergic modulator
5866 PH 797804
Potent and selective p38α/β inhibitor
3092 PHA 543613 hydrochloride
Potent and selective α7 nAChR agonist
3134 PHA 568487
Selective α7 nAChR agonist
2693 PHA 665752
Potent and selective MET inhibitor
3140 PHA 767491 hydrochloride
MK2 inhibitor; also cdk inhibitor; potently inhibits cdk9
1027 PHCCC
Potent group I mGlu antagonist
2080 PHM 27 (human)
Potent calcitonin agonist; endogenous analog of human VIP
4466 PHP 501 trifluoroacetate
Potent GABAA antagonist
6771 PHPS1 sodium salt
Shp2 (PTPN11) inhibitor
4598 PHT 427
Dual Akt and PDK1 inhibitor; antitumor
2662 PHTPP
Selective ERβ antagonist
2930 PI 103 hydrochloride
Inhibitor of PI 3-kinase, mTOR and DNA-PK
5919 PI 3065
Potent and selective PI 3-kinase p110δ inhibitor
2814 PI 828
PI 3-kinase inhibitor, more potent than LY 294002 (Cat. No. 1130)
6440 PIK 93
Potent PI 3-Kγ, PI 3-Kα and PI 4-KIIIβ inhibitor
3589 PIM-1 Inhibitor 2
Pim-1 kinase inhibitor
5889 PIPES, free acid
Commonly used buffer
4212 PIR 3.5
Negative control of IPA 3 (Cat. No. 3622)
1682 PIT
P2Y ligand; displays mixed antagonism/potentiation
4168 PIT 1
PIP3 antagonist. Blocks PIP3-PH interaction; inhibits Akt signaling
3255 PJ 34 hydrochloride
Potent PARP inhibitor
0670 PK 11195
Antagonist at peripheral benzodiazepine receptors
4145 PK 44 phosphate
Potent and selective dipeptidyl peptidase IV (DPP-IV) inhibitor
5338 PK-THPP
Potent K2P9.1 (TASK-3) channel blocker
1904 PKA inhibitor fragment (6-22) amide
Potent protein kinase A inhibitor
1882 PKA Tocriset™
Selection of 5 PKA modulators (Cat. Nos. 1337, 1140, 1099, 1288 and 1603)
2992 PKC 412
Protein kinase C inhibitor
1792 PKC β pseudosubstrate
Selective cell-permeable PKC inhibitor peptide (attached to vector)
1791 PKC ζ pseudosubstrate
PKC ζ inhibitor peptide (attached to cell-permeable vector)
6221 PKI (5-24)
High affinity PKA inhibitor
2546 PKI 14-22 amide, myristoylated
Cell-permeable protein kinase A inhibitor
4941 PKI 166 hydrochloride
Potent EGFR-kinase inhibitor
6580 PKUMDL WQ 2101
Negative allosteric modulator of 3-phosphoglycerate dehydrogenase (PHGDH)
6581 PKUMDL WQ 2201
Negative allosteric modulator of 3-Phosphoglycerate dehydrogenase (PHGDH)
2024 PL 017
Selective μ agonist
2567 PLP (139-151)
Encephalitogenic myelin proteolipid fragment
5102 PLX 647 dihydrochloride
Potent dual Fms/KIT inhibitor
4034 PM 102
Antagonist of heparin (Cat. No. 2812)
6220 PM 226
Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective
0627 2-PMDQ
Potent, selective α1 antagonist
1380 PMPA (NAALADase inhibitor)
GCP II inhibitor
2273 PMPA (NMDA antagonist)
Competitive NMDA antagonist
4486 PMSF
Non-selective protease inhibitor; also blocks anandamide metabolism
5196 PMX 205
Potent C5a receptor peptide antagonist
4996 PMX 464
Putative inhibitor of the Trx-TrxR system; antiproliferative
5473 PMX 53
Potent C5a receptor antagonist
5697 PMX 53c
Negative control for PMX 53 (Cat. No. 5473)
6891 PND 1186
Potent FAK inhibitor; orally bioavailable
6651 (2R/S)-6-PNG
CaV3.2 blocker; active in vivo
2498 PNU 120596
Positive allosteric modulator of α7 nAChRs; active in vivo
1985 PNU 142633
Highly selective 5-HT1D agonist
3355 PNU 177864 hydrochloride
Highly selective D3 antagonist
2201 PNU 22394 hydrochloride
5-HT2C agonist and 5-HT2A/2B partial agonist
2303 PNU 282987
Selective α7 nAChR agonist
2095 PNU 37883 hydrochloride
Vascular Kir6 (KATP) channel blocker
3534 PNU 74654
β-catenin binder; inhibits Wnt signaling
2735 PNU 96415E
D4 and 5-HT2A antagonist; antipsychotic
2689 POM 1
Inhibitor of E-NTPDases
1397 PP 1
Potent, selective Src family kinase inhibitor
3894 PP 121
Dual kinase inhibitor; inhibits PI 3-K family kinases
1407 PP 2
Potent, selective Src family kinase inhibitor
4257 PP 242
Dual mTORC1/mTORC2 inhibitor
2794 PP 3
Negative control for PP 2 (Cat. No. 1407)
6515 (D)-PPA 1
PD-1/PD-L1 interaction inhibitor
0625 PPADS tetrasodium salt
Non-selective P2 antagonist
0683 iso-PPADS tetrasodium salt
P2X antagonist
1466 PPAHV
Non-pungent vanilloid receptor agonist
0620 4-PPBP maleate
Specific σ ligand, NMDA antagonist
3870 (±)-PPCC oxalate
Selective sigma (σ) agonist (σ1> σ2)
2530 PPDA
GluN2C/GluN2D-selective NMDA antagonist
1034 4-P-PDOT
MT2 antagonist
1220 (RS)-PPG
Potent and selective mGlu8 agonist
1309 PPNDS
Potent, selective P2X1 antagonist
2274 PPPA
Competitive and GluN2A-selective NMDA antagonist
4303 PPQ 102
Potent, voltage-independent CFTR chloride channel inhibitor
1426 PPT
Subtype-selective ERα agonist
4862 PPTN hydrochloride
High affinity and selective P2Y14 antagonist
4730 PPY A
Potent inhibitor of Abl T315l mutant and wild-type Abl kinases
2768 PQ 401
IGF1R inhibitor
5351 PQ 69
Potent and selective A1 inverse agonist
1947 PR 39 (porcine)
IκBα inhibitor
4482 PR 619
Broad spectrum DUB inhibitor
0589 PRE-084 hydrochloride
Highly selective σ1 agonist
1862 PRIMA-1
Restores mutant p53 activity; induces apoptosis
3710 PRIMA-1MET
Restores mutant p53 activity
5047 PRT 4165
Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
6748 PRX 07034
Potent and selective 5-HT6 antagonist
4569 PS 1145 dihydrochloride
Selective IKK inhibitor; orally active
2715 PSB 0474
Potent and selective P2Y6 agonist
2574 PSB 06126
NTPDase 3 inhibitor
2573 PSB 069
Non-selective NTPDase inhibitor
3983 PSB 0739
Highly potent P2Y12 antagonist
4334 PSB 0777 ammonium salt
Potent adenosine A2A agonist
3199 PSB 0788
Selective A2B antagonist
2010 PSB 10 hydrochloride
Potent, highly selective hA3 receptor antagonist/inverse agonist
2012 PSB 11 hydrochloride
Potent, selective hA3 receptor antagonist/inverse agonist
4333 PSB 1114
Potent, selective P2Y2 agonist
2009 PSB 1115
Selective human A2B antagonist; water-soluble
6083 PSB 12379
Ecto-5'-nucleotidase (CD73) inhibitor
2019 PSB 36
Potent and selective A1 antagonist
3198 PSB 603
Highly selective A2B antagonist
6372 PSB CB5
Selective GPR18 antagonist
4042 PSC 833
Inhibitor of P-gp-mediated MDR
6425 PSEM 308 hydrochloride
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
6426 PSEM 89S
PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
3353 PSN 375963 hydrochloride
GPR119 receptor agonist
5321 PSNCBAM-1
Negative allosteric modulator of CB1 receptors
4039 PT 1
AMPK activator
4533 PTAC oxalate
Muscarinic receptor ligand; exhibits partial agonist and antagonist activity at different subtypes
5191 PTC 209
Bmi-1 inhibitor; antitumor
4604 PTIQ
Potent MMP-3 expression inhibitor; neuroprotective
4700 PU 02
Negative allosteric modulator of 5-HT3 receptors
6885 PU 23
Multidrug resistance protein (MRP) 4 inhibitor
3104 PU H71
Potent Hsp90 inhibitor
2954 PX 12
Thioredoxin-1 inhibitor
2978 PYR 41
Ubiquitin-activating enzyme (E1) inhibitor
4994 PYZD 4409
Ubiquitin-activating enzyme (E1) inhibitor
6192 PZ-II-029
α6β3γ2-selective GABAA positive allosteric modulator
4493 Paliperidone
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
0609 (±)-Palmitoylcarnitine chloride
Intermediate in fatty acid oxidation
0879 Palmitoylethanolamide
Selective GPR55 agonist. FAAH and PAA substrate
2206 2-Palmitoylglycerol
Endogenous lipid; enhances activity of 2-arachidonylglycerol (Cat. No. 1298)
1815 Palmitoylisopropylamide
Inhibitor of FAAH
7038 Palonosetron hydrochloride
Highly potent and high affinity 5-HT3 antagonist
4637 Pam2CSK4
TLR2/6 agonist; induces TNF-α production
4638 Pam2CSK4 Biotin
Biotinylated Pam2CSK4 (Cat. No. 4637)
4633 Pam3CSK4
TLR1/2 agonist; induces cytokine production
4298 Pamoic acid disodium salt
GPR35 agonist
1154 Pancreatic Polypeptide (human)
NPY Y4 agonist; involved in gastrointestinal tract function
1365 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
Potent, selective NPY Y5 agonist
0693 Pancuronium dibromide
Neuromusclar nAChR antagonist
4813 Paprotrain
Reversible inhibitor of MKLP-2
6303 Parathyroid hormone (1-34) (bovine)
Parathyroid hormone (PTH) receptor agonist
6301 Parathyroid hormone (1-34) (rat)
Parathyroid hormone (PTH) receptor agonist
3011 Parathyroid hormone (1-34) (human)
Parathyroid hormone (PTH) receptor agonist
4161 Paricalcitol
Analog of the active form of vitamin D2
2141 Paroxetine maleate
Highly potent and selective 5-HT uptake inhibitor
3553 Parstatin (human)
Peptide cleaved from PAR1 upon receptor activation
3554 Parstatin (mouse)
Peptide cleaved from PAR1 upon receptor activation
0610 Parthenolide
5-HT release inhibitor
2006 Paxilline
SERCA ATPase blocker. Also potent BKCa channel blocker
6349 Pelitinib
Potent and irreversible EGFR inhibitor; orally bioavailable
6185 Pemetrexed
Thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART
4617 Penitrem A
Potent and selective BKCa (KCa1.1) channel blocker
3692 4,4-Pentamethylenepiperidine hydrochloride
M2 proton channel blocker
3277 Pentamidine isethionate
NMDA antagonist: antimicrobial
5519 (-)-Pentazocine
κ-agonist; antinociceptive
4579 Pentobarbital sodium salt
Enhances GABAergic activity
2033 Pentostatin
Adenosine deaminase inhibitor
3056 Pentoxifylline
PDE inhibitor
4816 Pentoxyresorufin
Fluorometric cytochrome P450 substrate
2687 Pentylenetetrazole
CNS stimulant
6423 Pep 2-8
Potent PCSK9 inhibitor
1602 Pep1-AGL
GluA1 subunit C-terminus peptide analog; also analog of Pep1-TGL (Cat. No. 1601)
1601 Pep1-TGL
GluA1 subunit C-terminus peptide analog
1190 Pepstatin A
Aspartic protease inhibitor
1618 Peptide YY (3-36)
Selective NPY Y2 receptor agonist
6288 Peptide YY (3-36) human
NPY Y2 receptor agonist
6394 Peptide5
Connexin43 mimetic peptide
5166 Perhexiline maleate
Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor
6087 Perifosine
PKB/Akt inhibitor; also modulates Kv2.1 current
4302 Perindopril erbumine
Angiotensin-converting enzyme (ACE) inhibitor
5549 Perlapine
Potent muscarinc DREADD agonist
4944 Peroxy Orange 1
Fluorescent hydrogen peroxide indicator
3097 Pertussis Toxin
Catalyzes ADP-ribosylation of Gi, Go and Gt
6451 Pexacerfont
Potent and selective CRF1 antagonist; anxiolytic
4535 Phalloidin
Promotes actin polymerization
5782 Phalloidin-FITC
Green fluorescent cytoskeleton stain
6622 Phalloidin-TFAX 488
Green fluorescent cytoskeletal stain; binds F-actin
5783 Phalloidin-TRITC
Red-orange fluorescent cytoskeleton stain
3379 Phenamil
Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels
4999 9-Phenanthrol
Selective TRPM4 blocker
6385 Phenanthroline
Enhances hPSC differentiation into cranial placode cells
2557 Phencyclidine hydrochloride
Non-competitive NMDA antagonist
2967 Phenserine
Cholinesterase inhibitor
6431 Phentolamine Mesylate
Adrenergic α receptor antagonist; antihypertensive
0969 1-Phenylbiguanide hydrochloride
5-HT3 agonist
2682 Sodium 4-Phenylbutyrate
Histone deacetylase inhibitor
2838 (R)-(-)-Phenylephrine hydrochloride
α1 agonist
0680 2-Phenylmelatonin
Potent melatonin agonist
0730 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
DA release inhibitor
4326 PhiKan 083
p53 stabilizing agent
2770 Philanthotoxin 74
GluA1 and GluA3 selective AMPA antagonist
4627 Phlorizin
Na+-glucose cotransporter (SGLT) inhibitor
4153 Phorbol 12,13-dibutyrate
Protein kinase C activator
1201 Phorbol 12-myristate 13-acetate
Protein kinase C activator
4995 Phortress
Prodrug of the antitumor agent 5F 203
5778 2-Phospho-L-ascorbic acid trisodium salt
Ascorbic acid derivative; maintains differentiation potential in bone marrow-derived MSCs
1352 Phospho-Glycogen Synthase Peptide-2 (substrate)
Glycogen synthase kinase-3 substrate (synthetic)
4325 Phosphocreatine disodium salt
Phosphate reservoir
1881 Phosphodiesterase Inhibitor Tocriset™
Selection of 5 phosphodiesterase inhibitors (Cat. Nos. 0915, 1504, 0415, 1349 and 1046)
6333 Phosphoramidon disodium salt
Neutral endopeptidase and endothelin converting enzyme inhibitor
0238 O-Phospho-L-serine
Group III mGlu agonist
4914 Phrixotoxin 3
Potent blocker of NaV1.2, NaV1.3 and NaV1.5 channels
0622 Physostigmine hemisulfate
Cholinesterase inhibitor
1554 Piceatannol
Inhibits TNF-induced NF-κB activation
4525 Piclamilast
Potent and selective PDE4 inhibitor
2956 Picropodophyllotoxin
Selective IGF1R inhibitor
1128 Picrotoxin
GABAA antagonist
1267 Pifithrin-α hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist
3843 Cyclic Pifithrin-α hydrobromide
p53 inhibitor
2653 Pifithrin-μ
Inhibitor of p53-mitochondrial binding
0694 Pilocarpine hydrochloride
Muscarinic agonist
6182 Pimonidazole
Hypoxia detection reagent
0937 Pimozide
D2-like antagonist; also high affinity 5-HT7 antagonist
1060 (S)-(-)-Pindolol
β3 partial agonist; also 5-HT1A and 5-HT1B antagonist; more active enantiomer of pindolol (Cat. No. 0994)
4124 Pioglitazone hydrochloride
Selective PPARγ agonist; antidiabetic agent
0763 N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide
σ1 selective ligand
4396 Piperlongumine
Induces apoptosis; increases p53 and ROS levels in cancer cells
0736 2-[1-(4-Piperonyl)piperazinyl]benzothiazole
5-HT4 agonist; also 5-HT3 antagonist
2973 Piracetam
Modulates Na+-flux at AMPA receptors; nootropic
1071 Pirenzepine dihydrochloride
Selective M1 antagonist
1093 Pirfenidone
Antifibrotic agent; regulates cytokine levels in vivo
1031 Piribedil dihydrochloride
Dopamine agonist
0724 Pirlindole mesylate
MAO-A inhibitor
0960 Piroxicam
Cyclooxygenase-1 (COX-1) inhibitor
4942 Pitavastatin calcium
HMG-CoA reductase inhibitor
6070 Pladienolide B
mRNA splicing inhibitor; antitumor
4761 Plumbagin
Induces G2/M cell cycle arrest; anticancer
4847 PluriSln 1
SCD-1 inhibitor
4433 Pluripotin
Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
6991 Poly Vinyl Alcohol
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
4287 Poly(I:C)
TLR3 agonist
3197 Polygodial
TRPA1 channel activator; analgesic and antifungal
3165 Polyoxyethylenesorbitan monolaurate
Detergent used for protein extraction
6302 Pomalidomide
Cereblon ubiquitination inhibitor; also TNF-α inhibitor and antiangiogenic
6637 Pomalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6681 Pomalidomide 4'-PEG3-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
6963 Pomalidomide 4'-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6851 Pomalidomide 4'-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7205 Pomalidomide 4'-alkylC3-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6682 Pomalidomide 4'-alkylC5-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6716 Pomalidomide 4'-alkylC5-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6944 Pomalidomide 4'-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
1539 β-Pompilidotoxin
Slows neuronal Na+ channel inactivation
5225 Ponceau S Staining Solution
Stain used to detect protein bands after Western blotting
3147 Potassium chloride
Commonly used laboratory reagent
3150 Potassium phosphate monobasic
Commonly used in biological assay buffers
4174 Pramipexole dihydrochloride
Selective D3 agonist
5031 Pramlintide
Synthetic version of amylin (Cat. No. 3418)
6317 Prasugrel
Irreversible P2Y12 antagonist; antiplatelet and orally active
2318 Pravastatin sodium salt
HMG-CoA reductase inhibitor
0623 Prazosin hydrochloride
α1 and α2B antagonist; also MT3 antagonist
3775 Pregabalin
Anticonvulsant; selectively binds the α2δ subunit of voltage-sensitive calcium channels
3652 Pregnanolone
Postitive allosteric modulator of GABAA receptors
5376 Pregnenolone sulfate sodium salt
NMDA potentiator; also GABAA inhibitor and TRPM3 activator
0830 Primidone
Potentiates GABAA receptor function
3491 Prion Protein 106-126 (human)
Prion protein fragment
3731 Pristimerin
Potent, reversible MAGL inhibitor
4998 ProINDY
DYRK1A/B inhibitor; prodrug of INDY (Cat. No. 4997)
4665 ProTx I
CaV3.1 blocker; also inhibits NaV1.8 and KV2.1
4023 ProTx II
Selective NaV1.7 channel blocker
5792 ProTx III
Potent Nav1.7 blocker; analgesic
4107 Probenecid
MRP inhibitor
2775 Probucol
ABCA1 (CERP) inhibitor; also antioxidant, anti-inflammatory and hypocholesterolemic agent
1102 Procaterol hydrochloride
Potent β2 agonist
3287 Prochlorperazine dimaleate
D2 receptor antagonist; also 5-HT3 and nAChR antagonist
2835 Progesterone
Endogenous progesterone receptor agonist
1478 Proglumide sodium salt
Non-selective CCK antagonist; orally active
0829 Pronethalol hydrochloride
β antagonist
5135 Propidium iodide
Red-fluorescent DNA stain; membrane impermeant to live cells. Pi staining differentiates live and dead cells
0611 (±)-Propionylcarnitine chloride
Intermediate in lipid metabolism
0624 Propranolol hydrochloride
β antagonist
0851 Propranolol glycol
Propranolol (Cat. No. 0624) metabolite
0835 (R)-(+)-Propranolol hydrochloride
β antagonist. Less active enantiomer of propranolol (Cat. No. 0624)
0834 (S)-(-)-Propranolol hydrochloride
β antagonist. More active enantiomer of propranolol (Cat. No. 0624)
1200 Nω-Propyl-L-arginine hydrochloride
Highly selective inhibitor of nNOS
5151 Prosaptide TX14(A)
Potent GPR37 and GPR37L1 agonist
2296 Prostaglandin E2
Major endogenous prostanoid
4214 Prostaglandin F2α
Naturally-occurring prostanoid; potent vasoconstrictor
2306 15-deoxy-Δ-12,14-Prostaglandin J2
Endogenous PPARγ agonist
5739 Prostratin
PKC activator; also NF-κB activator
5500 Protease Inhibitor Cocktail I
Protease inhibitor cocktail for mammalian cells
2477 Proxyfan oxalate
High affinity H3 ligand
5042 Psalmotoxin 1
Potent and selective ASIC1a channel blocker
1790 Pseudo RACK1
Protein kinase C activator peptide (attached to cell permeable vector)
4367 Psora 4
Potent KV1.3 channel blocker
3384 (Z)-Pugnac
O-GlcNAcase and β-hexosaminidase inhibitor
4551 Purmorphamine
Smo receptor agonist
4089 Puromycin dihydrochloride
Protein synthesis inhibitor
1580 Purvalanol A
Cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
1581 Purvalanol B
Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
3751 Pyr3
Selective TRPC3 blocker
6577 Pyridone 6
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
4763 Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
2478 2-Pyridylethylamine dihydrochloride
H1 agonist
3918 Pyrimethamine
Potent inhibitor of multidrug and toxin extrusion (MATE) transporters; also DHFR and STAT3 inhibitor
4978 Pyrintegrin
Enhances survival of human ESCs following enzymatic dissociation
4403 Pyroxamide
Histone deacetylase inhibitor
0727 Pyrrolidinedithiocarbamate ammonium
Inhibits NF-κB, prevents increase in NOS mRNA

Tocris Products by Catalog Number