All Products

Displaying Products by Catalog Number (6900 - 6999)

Cat. No. Product Name / Activity
6900 NNMTi
Nicotinamide N-methyltransferase (NNMT) inhibitor; promotes myoblast differentiation
6902 Dapansutrile
NLRP3 inflammasome inhibitor; disrupts inflammasome formation
6903 DPTIP
Potent and selective N-SMase2 inhibitor; brain penetrant
6904 Idasanutlin
Potent MDM2 inhibitor; inhibits MDM2-p53 interaction
6905 Ceritinib
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
6906 BAY 293 Negative Control
Negative control for BAY 293 (Cat. No. 6857)
6907 VH 032 amide-PEG2-amine
VHL ligand with PEG linker and terminal amine for onward chemistry
6908 TR 14035
Potent integrin α4β7 and α4β1 (VLA-4) antagonist; orally bioavailable
6909 VH 032 phenol-alkylC4-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6910 VH 032 phenol-alkylC6-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6911 VH 032, phenol
Hydroxyl functionalized VHL ligand
6912 dTAG-7
First generation Degrader for mutant FKBP12F36V fusion proteins; useful alternative to genetic methods for target validation
6917 Thalidomide 4'-ether-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6920 SAH-SOS1A
KRas/SOS1 interaction inhibitor
6921 BSJ-03-123
Selective Cdk6 degrader
6922 BSJ-Bump
Negative control for BSJ-03-123 (Cat. No. 6921)
6924 Oridonin
High affinity NLRP3 inflammasome inhibitor
6925 NBC 6
NLRP3 inflammasome inhibitor
6926 Fenoprofen calcium
Positive allosteric modulator of MC3 receptors; exhibits biased signaling
6927 Glucagon (Human, Porcine)
Endogenous glucagon receptor agonist
6928 VU 6001966
Potent and selective negative allosteric modulator of mGlu2 receptors
6930 Amphotericin B
Forms monovalent ion channels in lipid bilyers; antifungal
6931 AF 64394
Potent and selective GPR3 inverse agonist
6932 VU 0467485
Potent and selective positive allosteric modulator of M4 receptors; orally bioavailable and brain penetrant
6933 CM 10
ALDH1A inhibitor; depletes CD133+ cancer stem cells
6934 673 A
ALDH1A inhibitor; depletes CD133+ cancer stem cells (CSC)
6935 GSK J5 HCl
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
6936 VZ 185
Potent and selective BRD7/9 Degrader
6937 BSJ-04-132
Selective Cdk4 degrader
6938 BSJ-03-204
Selective Cdk4/6 degrader
6939 cis-VZ 185
Negative control for VZ 185 (Cat. No. 6936)
6940 BTD
Selective TRPC5 activator
6944 Pomalidomide 4'-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6946 Thalidomide 4'-oxyacetamide-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6948 CRBN-6-5-5-VHL
Potent and selective cereblon degrader; cell-permeable
6949 Thalidomide 4'-oxyacetamide-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6950 Thalidomide 4'-ether-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6951 Thalidomide 4'-ether-PEG5-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6952 VH 101, phenol
Hydroxyl functionalized VHL ligand
6954 L-Buthionine sulfoximine
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis
6956 Galunisertib
ALK4 and ALK5 (TGFβRI) inhibitor
6957 Reparixin L-lysine salt
Potent CXCR1 and CXCR2 allosteric antagonist
6960 ABT 199
Selective, high affinity Bcl-2 inhibitor; orally bioavailable
6961 FzM1.8
Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness
6962 JBJ-03-142-02
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
6963 Pomalidomide 4'-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6964 LY 2119620
Positive allosteric modulator of M2 and M4 receptors
6966 Thalidomide 4'-oxyacetamide-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6967 Thalidomide 4'-oxyacetamide-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6968 Thalidomide 4'-oxyacetamide-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6969 cis VH 032, amine dihydrochloride
Negative control for VH 032, amine (Cat. No. 6462)
6970 aTAG 2139
Degrader of MTH1 fusion proteins for use within the aTAG system
6971 aTAG 4531
Degrader of MTH1 fusion proteins for use within the aTAG system
6972 A 1899
Potent K2P3.1 (TASK-1) and K2P9.1 (TASK-3) blocker
6974 BMS 986094
Inhibitor of HCV RNA-dependent RNA polymerase NS5b; potent hepatitis C virus (HCV) replication inhibitor
6976 JNJ 10198409
Potent PDGFRα and PDGFRβ inhbitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
6978 AZD 5363
Potent pan-AKT inhibitor
6980 BAY 87-2243
Mitochondrial complex I inhibitor
6981 TL 0259
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
6982 Cyclosporin H
Enhances lentiviral transduction
6985 VH 032 amide-alkylC5-amine
VHL ligand with alkyl linker and terminal amine for onward chemistry
6986 EG 00229 trifluoroacetate
Neuropilin 1 (NRP1) receptor antagonist; inhibits VEGFA binding to NRP1
6991 Poly Vinyl Alcohol
Carrier molecule for stem cell culture; replaces serum albumin for ex vivo stem cell expansion
6993 Janelia Fluor® 646, free acid
Red dye (Reactive group: free acid). Applications: super resolution microscopy e.g. dSTORM & STED, confocal, flow and live cell imaging
6994 HODHBt
STAT5-SUMO protein-protein interaction inhibitor
6998 SHIN 1
Potent SHMT inhibitor

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