Alprenolol hydrochloride

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Cat.No. 2806 - Alprenolol hydrochloride | C15H23NO2.HCl | CAS No. 13707-88-5
Description: β antagonist
Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

β-adrenoceptor (β2 > β1 > β3) and 5-HT1A receptor antagonist.

Technical Data

M. Wt 285.81
Formula C15H23NO2.HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 13707-88-5
PubChem ID 66368
InChI Key RRCPAXJDDNWJBI-UHFFFAOYSA-N
Smiles C=CCC1=CC=CC=C1OCC(O)CNC(C)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 28.58 100

Preparing Stock Solutions

The following data is based on the product molecular weight 285.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.5 mL 17.49 mL 34.99 mL
5 mM 0.7 mL 3.5 mL 7 mL
10 mM 0.35 mL 1.75 mL 3.5 mL
50 mM 0.07 mL 0.35 mL 0.7 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Blue et al (1990) Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol. J.Pharmacol.Exp.Ther. 252 1034 PMID: 1969469

Bjorvatin et al (1992) The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats. Pharmacol.Biochem.Behav. 42 49 PMID: 1388278

Baker (2005) The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br.J.Pharmacol. 144 317 PMID: 15655528


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Citations for Alprenolol hydrochloride

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