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Displaying Products Alphabetically by Name (L)

Cat. No. Product Name / Activity
3066 L 006235
Potent cathepsin K inhibitor
5085 L 012 sodium salt
Chemiluminescent ROS and RNS indicator
4013 L 760735
High affinity NK1 antagonist
6251 L Moses dihydrochloride
High affinity and selective PCAF bromodomain inhibitor
1382 L-152,804
Potent, selective non-peptide NPY Y5 receptor antagonist
2514 L-161,982
Selective EP4 receptor antagonist
2311 L-168,049
Potent, orally active human glucagon receptor antagonist
2767 L-365,260
Selective CCK2 antagonist
2641 L-368,899 hydrochloride
Potent, non-peptide oxytocin receptor antagonist
2410 L-371,257
Potent and selective oxytocin receptor antagonist
3086 L-651,582
Non-selective Ca2+ channel blocker
1327 L-655,708
Benzodiazepine inverse agonist; selective for α5-containing GABAA receptors
2627 L-685,458
Potent and selective γ-secretase inhibitor
0742 L-689,560
Highly potent NMDA antagonist
0681 L-690,330
Inositol monophosphatase inhibitor
0907 L-701,324
NMDA antagonist; acts at glycine site
1145 L-733,060 hydrochloride
Potent NK1 antagonist
1004 L-741,742 hydrochloride
Highly selective D4 antagonist
1003 L-741,626
High affinity D2 antagonist
1002 L-745,870 trihydrochloride
Highly selective D4 antagonist
2760 L-748,337
Selective β3 antagonist
2197 L-755,507
Very potent and selective β3 partial agonist
3342 L-798,106
Potent and highly selective EP3 antagonist
1980 L-817,818
Potent and selective sst5 agonist
3250 L-838,417
GABAA partial agonist; displays subtype selectivity
6954 L-Buthionine sulfoximine
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis
3788 L-DOPA
Dopamine precursor
6146 LAP
Photocrosslinker for hydrogels
7420 LC 2
Selective KRAS Degrader (PROTAC®)
7421 LC 2 Epimer
Negative control for LC 2 (Cat. No. 7420)
5592 LCB 03-0110 dihydrochloride
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
7178 LCL 161, phenol
Functionalized IAP ligand for PROTACs
5631 LDN 193188
Inhibitor of phosphatidylcholine transfer protein (PC-TP)
6053 LDN 193189 dihydrochloride
Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs
8150 LDN 193189 in solution
Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water
TB6053-GMP LDN 193189
LDN 193189 synthesized to cGMP guidelines
7020 LDV
α4β1 (VLA-4) ligand
4577 LDV FITC
Fluorescent ligand for α4β1 (VLA-4)
2021 LE 135
Selective RARβ antagonist
1674 LE 300
Potent and selective D1 antagonist
5826 LEI 101 hydrochloride
Potent and selective CB2 partial agonist; orally biovailable
7407 LEI 401
High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
1300 LFM-A13
Potent, selective BTK inhibitor
5920 LG 100268
Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers
8095 LIH 383
Atypical chemokine receptor (ACKR3) agonist
4745 LIMKi 3
Potent LIM kinase inhibitor; antitumor
6754 LJI308
Potent pan-RSK inhibitor
5213 LL 37
Antimicrobial peptide derivative of human cathelicidin
7813 LL-K9-3
Selective HyT-based degrader of the CDK9-cyclin T1 complex
4607 LM 22A4
Potent TrkB agonist
6037 LM22B 10
TrkB and TrkC agonist; brain penetrant
6510 LNT 1
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
6691 LP 922056
Notum inhibitor; activates Wnt signaling
5496 LP 99
Selective BRD7 and BRD9 inhibitor
4273 LRRK2-IN-1
Potent and selective LRRK2 inhibitor
5275 LSN 2463359
Potent and selective positive allosteric modulator of mGlu5 receptors
7959 LSN 3318839
Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator
5834 LTURM 34
Potent DNA-PK inhibitor; also increases CRISPR-Cas9 deletion efficiency
3562 LU AA33810
Potent NPY Y5 receptor antagonist
4603 LUF 5834
Potent adenosine A2A and A2B receptor partial agonist
6322 LW 6
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
7027 LY 2033298
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
4141 LY 2087101
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
7864 LY 2109761
Selective TGF-β kinase inhibitor
6964 LY 2119620
Positive allosteric modulator of M2 and M4 receptors
3397 LY 2365109 hydrochloride
Potent and selective GlyT1 inhibitor
2208 LY 255283
Selective, competitive BLT2 receptor antagonist
6454 LY 2603618
Potent and selective Chk1 inhibitor
4081 LY 266097 hydrochloride
Selective 5-HT2B antagonist
3077 LY 272015 hydrochloride
High affinity 5-HT2B antagonist; orally active
1524 LY 288513
Selective CCK2 antagonist
7081 LY 2886721 Hydrochloride
Potent and selective β-secretase (BACE) inhibitor
1130 LY 294002 hydrochloride
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
5984 LY 2955303
High affinity and selective RARγ antagonist
3078 LY 310762 hydrochloride
Selective 5-HT1D antagonist
1209 LY 341495
Highly potent and selective group II mGlu antagonist
4062 LY 341495 disodium salt
Potent and selective group II mGlu antagonist; disodium salt of LY 341495 (Cat. No. 1209)
2451 LY 344864 hydrochloride
Potent and selective 5-HT1F agonist
3246 LY 354740
Potent and highly selective group II mGlu agonist
1237 LY 367385
Selective mGlu1a antagonist
2453 LY 379268
Highly selective group II mGlu agonist
5064 LY 379268 disodium salt
Selective group II mGlu agonist; sodium salt of LY 379268 (Cat. No. 2453)
5297 LY 404187
Selective positive allosteric modulator of AMPA receptors
6559 LY 450139
γ-secretase pseudo-inhibitor
2390 LY 456236 hydrochloride
Selective mGlu1 antagonist
3283 LY 487379 hydrochloride
Selective positive allosteric modulator of mGlu2 receptors
6617 LYN 1604 dihydrochloride
Potent UNC-51-like kinase 1 (ULK1) agonist
8888 LaKe
Orally bioavailable prodrug metabolite, undergoes hydrolytic conversion to yield (S)-lactate and (R)-1,3-butanediol in cells
7942 Lac-Phe
Metabolite generated by cytosol nonspecific dipeptidase (CNDP2) during intense exercise
2267 Lactacystin
Cell-permeable, potent and selective proteasome inhibitor
6098 Lalistat 1
Potent and selective LAL inhibitor
6099 Lalistat 2
Selective LAL inhibitor
1611 Lamotrigine
Inhibits glutamate release. Anticonvulsant
2289 Lamotrigine isethionate
Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)
6811 Lapatinib
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
7343 Laropiprant
Potent and selective prostaglandin D2 receptor antagonist
3973 Latrunculin A
Inhibitor of actin assembly and polymerization
3974 Latrunculin B
Inhibitor of actin polymerization
7275 Laurdan
Polarity sensitive lipid membrane fluorescent probe. Used for: imaging lipid rafts. Application: fluorescent microscopy
2460 Lazabemide hydrochloride
Selective MAO-B inhibitor
6305 Lenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
7075 Lenalidomide 4'-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7513 Lenalidomide 4'-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7093 Lenalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7514 Lenalidomide 4'-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7076 Lenalidomide 4'-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7516 Lenalidomide 4'-alkylC3-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7517 Lenalidomide 4'-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7677 Lenalidomide 5'-amine
Cereblon ligand with terminal amine for onward chemistry
7472 Lenalidomide 5'-piperazine
Cereblon ligand with terminal piperazine for onward chemistry
7473 Lenalidomide 5'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
8848 Lenalidomide 5'-piperazine-7'-methoxy
Cereblon ligand with terminal piperazine for onward chemistry
3395 Lestaurtinib
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
4382 Letrozole
Potent, reversible non-steroidal aromatase inhibitor
2307 Leukotriene B4
BLT1/BLT2 receptor agonist and potent chemotactic factor
1167 Leupeptin hemisulfate
Inhibits trypsin-like/cysteine proteases
1378 Levcromakalim
Kir6 (KATP) channel opener; active enantiomer of Cromakalim
2839 Levetiracetam
Binds SV2A; antiepileptic
2705 Liarozole dihydrochloride
Blocks retinoic acid metabolism
3865 Licarbazepine
Active metabolite of oxcarbazepine (Cat. No. 3864)
3057 Lidocaine
Na+ channel blocker
6068 Lin28 1632
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
3765 Linezolid
Antibiotic; inhibits protein synthesis in gram-positive bacteria
7743 Linifanib
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
1999 Linopirdine dihydrochloride
KV7 (KCNQ) channel blocker
7652 Linsitinib
Potent and selective dual inhibitor of the IGF-1 receptor and insulin receptor
6113 Liproxstatin-1 hydrochloride
Potent ferroptosis inhibitor
6517 Liraglutide
Highly potent, long-acting GLP-1 receptor agonist
4052 Lisuride maleate
Dopamine agonist; antiparkinson's agent
4359 Lomeguatrib
MGMT inhibitor
7492 Lomitapide mesylate
Potent microsomal triglyceride transfer protein (MTP) inhibitor
6265 Lonafarnib
Potent farnesyltransferase inhibitor
1646 Lonidamine
Mitochondrial hexokinase inhibitor
7052 Lopinavir
Highly potent and selective HIV-1 protease inhibitor
1295 Loreclezole hydrochloride
Subtype-selective GABAA modulator
3798 Losartan potassium
Selective, non-peptide AT1 antagonist
1530 Lovastatin
Potent HMG-CoA reductase inhibitor
3036 Loxiglumide
CCK1 antagonist; active in vivo
5427 D-Luciferin sodium salt
Firefly luciferase substrate; cell permeable.
2874 Luteolin
Anti-inflammatory, antioxidant and free radical scavenger
0877 Luzindole
Competitive melatonin MT1/MT2 antagonist

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