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Displaying Products Alphabetically by Name (L)

Cat. No. Product Name / Activity
3066 L 006235
Potent cathepsin K inhibitor
5085 L 012 sodium salt
Chemiluminescent ROS and RNS indicator
4013 L 760735
High affinity NK1 antagonist
6251 L Moses dihydrochloride
High affinity and selective PCAF bromodomain inhibitor
2444 (1R,1'S,3'R/1R,1'R,3'S)-L-054,264
Potent and selective sst2 agonist
1382 L-152,804
Potent, selective non-peptide NPY Y5 receptor antagonist
2514 L-161,982
Selective EP4 receptor antagonist
1856 L-165,041
Potent PPARδ agonist
2311 L-168,049
Potent, orally active human glucagon receptor antagonist
2660 L-364,373
KV7.1 channel activator, activates IKs
2767 L-365,260
Selective CCK2 antagonist
2641 L-368,899 hydrochloride
Potent, non-peptide oxytocin receptor antagonist
2410 L-371,257
Potent and selective oxytocin receptor antagonist
3086 L-651,582
Non-selective Ca2+ channel blocker
1327 L-655,708
Benzodiazepine inverse agonist; selective for α5-containing GABAA receptors
2627 L-685,458
Potent and selective γ-secretase inhibitor
0742 L-689,560
Highly potent NMDA antagonist
0681 L-690,330
Inositol monophosphatase inhibitor
2261 L-692,585
Potent, non-peptide ghrelin receptor agonist
0705 L-701,252
NMDA antagonist; acts at glycine site
0907 L-701,324
NMDA antagonist; acts at glycine site
2640 L-703,664 succinate
Selective 5-HT1D agonist
0868 L-732,138
Potent and selective NK1 antagonist
1145 L-733,060 hydrochloride
Potent NK1 antagonist
1004 L-741,742 hydrochloride
Highly selective D4 antagonist
1003 L-741,626
High affinity D2 antagonist
1002 L-745,870 trihydrochloride
Highly selective D4 antagonist
2760 L-748,337
Selective β3 antagonist
2197 L-755,507
Very potent and selective β3 partial agonist
3342 L-798,106
Potent and highly selective EP3 antagonist
1979 L-803,087 trifluoroacetate
Potent and selective sst4 agonist
1980 L-817,818
Potent and selective sst5 agonist
3250 L-838,417
GABAA partial agonist; displays subtype selectivity
6954 L-Buthionine sulfoximine
Irreversible γ-glutamylcysteine synthetase (γ-GCS) inhibitor; induces ferroptosis
6809 L-DON
Glutaminase inhibitor; also inhibits other glutamine-using enzymes and transporters
3788 L-DOPA
Dopamine precursor
5045 L002
p300 inhibitor
3561 L189
DNA ligase I, III and IV inhibitor
6146 LAP
Photocrosslinker for hydrogels
7420 LC 2
Selective KRAS PROTAC®
7421 LC 2 Epimer
Negative control for LC 2 (Cat. No. 7420)
5592 LCB 03-0110 dihydrochloride
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
7178 LCL 161, phenol
Functionalized IAP ligand for PROTACs
6752 LDC 000067
Potent and selective CDK9 inhibitor
5631 LDN 193188
Inhibitor of phosphatidylcholine transfer protein (PC-TP)
6053 LDN 193189 dihydrochloride
Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs
TB6053-RMU LDN 193189
LDN 193189 synthesized to Ancillary Material Grade
4828 LDN 209929 dihydrochloride
Potent and selective haspin inhibitor
5082 LDN 212320
Increases EAAT2 expression; neuroprotective
6151 LDN 212854
Potent bone morphogenetic protein type I (ALK) inhibitor
6152 LDN 214117
Potent and selective ALK2 inhibitor
4602 LDN 27219
Transglutaminase 2 (TG2) inhibitor; reversible
3998 LDN 57444
Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor
7020 LDV
α4β1 (VLA-4) ligand
4577 LDV FITC
Fluorescent ligand for α4β1 (VLA-4)
2021 LE 135
Selective RARβ antagonist
1674 LE 300
Potent and selective D1 antagonist
5826 LEI 101 hydrochloride
Potent and selective CB2 partial agonist; orally biovailable
7407 LEI 401
High affinity N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor
2985 LEP (116-130) (mouse)
Synthetic leptin peptide fragment
1300 LFM-A13
Potent, selective BTK inhibitor
5920 LG 100268
Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers
3508 LG 101506
Selective RXR modulator
4896 LH 846
Selective casein kinase 1δ inhibitor
4745 LIMKi 3
Potent LIM kinase inhibitor; antitumor
6754 LJI308
Potent pan-RSK inhibitor
5213 LL 37
Antimicrobial peptide derivative of human cathelicidin
5794 LM 10
Selective tryptophan 2,3-dioxygenase (TDO) inhibitor
4607 LM 22A4
Potent TrkB agonist
5046 LM11A 31 dihydrochloride
Nonpeptide p75NTR ligand; neuroprotective
6037 LM22B 10
TrkB and TrkC agonist; brain penetrant
4830 LMK 235
Selective HDAC4/HDAC5 inhibitor
6510 LNT 1
Potent flap endonuclease 1 (FEN1) inhibitor; induces DNA damage response
5606 LOC14
High affinity protein disulfide isomerase (PDI) modulator
2314 LOE 908 hydrochloride
Broad spectrum cation channel blocker; neuroprotective
6691 LP 922056
Notum inhibitor; activates Wnt signaling
6229 LP 922761
Potent AAK1 inhibitor; peripherally restricted
5496 LP 99
Selective BRD7 and BRD9 inhibitor
3394 LRGILS-NH2
Control peptide for SLIGRL-NH2 (Cat. No. 1468)
4273 LRRK2-IN-1
Potent and selective LRRK2 inhibitor
5275 LSN 2463359
Potent and selective positive allosteric modulator of mGlu5 receptors
5834 LTURM 34
Potent DNA-PK inhibitor
5835 LTURM 36
PI 3-kinase δ inhibitor
3562 LU AA33810
Potent NPY Y5 receptor antagonist
4603 LUF 5834
Potent adenosine A2A and A2B receptor partial agonist
4881 LUF 6283
HCA2 (GPR109A) partial agonist
6322 LW 6
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
7027 LY 2033298
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
4141 LY 2087101
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
6964 LY 2119620
Positive allosteric modulator of M2 and M4 receptors
2452 LY 2183240
Highly potent anandamide uptake inhibitor; also inhibits FAAH
1018 LY 225910
Potent CCK2 antagonist
1286 LY 231617
Antioxidant; neuroprotective in vitro and in vivo
1019 LY 235959
Competitive NMDA antagonist
3397 LY 2365109 hydrochloride
Potent and selective GlyT1 inhibitor
4969 LY 2389575 hydrochloride
Selective negative allosteric modulator of mGlu3 receptors
2208 LY 255283
Selective, competitive BLT2 receptor antagonist
6454 LY 2603618
Potent and selective Chk1 inhibitor
4081 LY 266097 hydrochloride
Selective 5-HT2B antagonist
3077 LY 272015 hydrochloride
High affinity 5-HT2B antagonist; orally active
1524 LY 288513
Selective CCK2 antagonist
7081 LY 2886721 Hydrochloride
Potent and selective β-secretase (BACE) inhibitor
1130 LY 294002 hydrochloride
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
5984 LY 2955303
High affinity and selective RARγ antagonist
6854 LY 3009120
Potent pan-Raf kinase inhibitor
2418 LY 303511
Negative control of LY 294002 (Cat. No. 1130)
3078 LY 310762 hydrochloride
Selective 5-HT1D antagonist
2387 LY 320135
Selective CB1 inverse agonist
3079 LY 334370 hydrochloride
Selective 5-HT1F agonist
1209 LY 341495
Highly potent and selective group II mGlu antagonist
4062 LY 341495 disodium salt
Potent and selective group II mGlu antagonist; disodium salt of LY 341495 (Cat. No. 1209)
2451 LY 344864 hydrochloride
Potent and selective 5-HT1F agonist
3246 LY 354740
Potent and highly selective group II mGlu agonist
2718 LY 364947
Selective inhibitor of TGF-βRI
1237 LY 367385
Selective mGlu1a antagonist
2453 LY 379268
Highly selective group II mGlu agonist
5064 LY 379268 disodium salt
Selective group II mGlu agonist; sodium salt of LY 379268 (Cat. No. 2453)
3272 (±)-LY 395756
Mixed mGlu2 agonist/ mGlu3 antagonist
5297 LY 404187
Selective positive allosteric modulator of AMPA receptors
6559 LY 450139
γ-secretase pseudo-inhibitor
2390 LY 456236 hydrochloride
Selective mGlu1 antagonist
3283 LY 487379 hydrochloride
Selective positive allosteric modulator of mGlu2 receptors
4060 LY 78335
Phenylethanolamine-N-methyltransferase inhibitor
2267 Lactacystin
Cell-permeable, potent and selective proteasome inhibitor
6098 Lalistat 1
Potent and selective LAL inhibitor
6099 Lalistat 2
Selective LAL inhibitor
1611 Lamotrigine
Inhibits glutamate release. Anticonvulsant
2289 Lamotrigine isethionate
Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)
1293 β-Lapachone
DNA topoisomerase I inhibitor
6811 Lapatinib
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
3973 Latrunculin A
Inhibitor of actin assembly and polymerization
3974 Latrunculin B
Inhibitor of actin polymerization
4007 Laulimalide
Microtubule stabilzing agent
7275 Laurdan
Polarity sensitive lipid membrane fluorescent probe; used to imaging lipid rafts
1331 Lavendustin A
EGFR, p60c-src inhibitor
2460 Lazabemide hydrochloride
Selective MAO-B inhibitor
5571 Lei-Dab 7
High affinity and selective KCa2.2 (SK) blocker
6305 Lenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
7075 Lenalidomide 4'-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7513 Lenalidomide 4'-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7093 Lenalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7514 Lenalidomide 4'-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7076 Lenalidomide 4'-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7517 Lenalidomide 4'-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7472 Lenalidomide 5'-piperazine
Cereblon ligand with terminal piperazine for onward chemistry
7473 Lenalidomide 5'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
1987 Leptomycin B
Inhibits nuclear export of proteins; antitumor
3395 Lestaurtinib
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
4382 Letrozole
Potent, reversible non-steroidal aromatase inhibitor
4921 Leukadherin 1
Allosteric activator of CD11b/CD18
2307 Leukotriene B4
BLT1/BLT2 receptor agonist and potent chemotactic factor
1167 Leupeptin hemisulfate
Inhibits trypsin-like/cysteine proteases
1378 Levcromakalim
Kir6 (KATP) channel opener; active enantiomer of cromakalim (Cat. No. 1377)
2839 Levetiracetam
Binds SV2A; antiepileptic
4833 Levonorgestrel
Synthetic progesterone analog
2705 Liarozole dihydrochloride
Blocks retinoic acid metabolism
3865 Licarbazepine
Active metabolite of oxcarbazepine (Cat. No. 3864)
3057 Lidocaine
Na+ channel blocker
6068 Lin28 1632
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
3765 Linezolid
Antibiotic; inhibits protein synthesis in gram-positive bacteria
1999 Linopirdine dihydrochloride
KV7 (KCNQ) channel blocker
7045 (±)-α-Lipoamide
Phase-separated condensate modifier; orally bioavailable
7044 (±)-α-Lipoic acid
Liquid-liquid phase separated condensate modifier; reduces stress granule formation
6113 Liproxstatin-1 hydrochloride
Potent ferroptosis inhibitor
6517 Liraglutide
Highly potent, long-acting GLP-1 receptor agonist
4052 Lisuride maleate
Dopamine agonist; antiparkinson's agent
4740 Lithium carbonate
Mood stabilizer; inhibits GSK-3 in vivo
1916 Litorin
Amphibian bombesin-like peptide
1077 (-)-Lobeline hydrochloride
Nicotinic partial agonist
2545 Lofepramine
5-HT and NA reuptake inhibitor (SNRI)
4359 Lomeguatrib
MGMT inhibitor
6265 Lonafarnib
Potent farnesyltransferase inhibitor
1646 Lonidamine
Mitochondrial hexokinase inhibitor
0840 Loperamide hydrochloride
Peripherally acting μ agonist; Ca2+ channel blocker
7052 Lopinavir
Highly potent and selective HIV-1 protease inhibitor
1944 Loratidine
Peripheral H1 antagonist; antiallergic agent
1295 Loreclezole hydrochloride
Subtype-selective GABAA modulator
3798 Losartan potassium
Selective, non-peptide AT1 antagonist
1530 Lovastatin
Potent HMG-CoA reductase inhibitor
3036 Loxiglumide
CCK1 antagonist; active in vivo
5427 D-Luciferin sodium salt
Firefly luciferase substrate; cell permeable.
2874 Luteolin
Anti-inflammatory, antioxidant and free radical scavenger
0877 Luzindole
Competitive melatonin MT1/MT2 antagonist
2265 Lyn peptide inhibitor
Inhibits Lyn-dependent activities of IL-5 receptor; cell-permeable
5103 Lys-CoA
Selective p300 inhibitor
3611 Lys-γ3-MSH
Pro-opiomelanocortin (POMC) derived peptide

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