Adenosine

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Cat.No. 3624 - Adenosine | C10H13N5O4 | CAS No. 58-61-7
Description: Endogenous adenosine receptor agonist
Chemical Name: 9-β-D-Ribofuranosyl-9H-purin-6-amine
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (4)

Biological Activity

Neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes.

Compound Libraries

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Technical Data

M. Wt 267.24
Formula C10H13N5O4
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 58-61-7
PubChem ID 60961
InChI Key OIRDTQYFTABQOQ-KQYNXXCUSA-N
Smiles O[C@@H]1[C@@H](CO)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 2.67 10
DMSO 20.04 75

Preparing Stock Solutions

The following data is based on the product molecular weight 267.24. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 4.99 mL 24.95 mL 49.89 mL
3.75 mM 1 mL 4.99 mL 9.98 mL
7.5 mM 0.5 mL 2.49 mL 4.99 mL
37.5 mM 0.1 mL 0.5 mL 1 mL

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References

References are publications that support the biological activity of the product.

Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247 PMID: 16518376


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Keywords: Adenosine, Adenosine supplier, Endogenous, adenosines, receptor, agonists, Non-Selective, Receptors, Non-selective, Adenosine, 3624, Tocris Bioscience

2 Citations for Adenosine

Citations are publications that use Tocris products. Selected citations for Adenosine include:

Bumpus and Johnson (2011) 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated J Neurosci 339 886 PMID: 21896918

Hamby et al (2012) Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. PLoS One 32 14489 PMID: 23077035


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Reviews for Adenosine

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Literature in this Area

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