Adenosine

Pricing Availability Delivery Time Qty
Cat.No. 3624 - Adenosine | C10H13N5O4 | CAS No. 58-61-7
Description: Endogenous adenosine receptor agonist
Chemical Name: 9-β-D-Ribofuranosyl-9H-purin-6-amine
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes.

Technical Data

M. Wt 267.24
Formula C10H13N5O4
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 58-61-7
PubChem ID 60961
InChI Key OIRDTQYFTABQOQ-KQYNXXCUSA-N
Smiles O[C@@H]1[C@@H](CO)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.04 75
water 2.67 10

Preparing Stock Solutions

The following data is based on the product molecular weight 267.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.74 mL 18.71 mL 37.42 mL
5 mM 0.75 mL 3.74 mL 7.48 mL
10 mM 0.37 mL 1.87 mL 3.74 mL
50 mM 0.07 mL 0.37 mL 0.75 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247 PMID: 16518376


If you know of a relevant reference for Adenosine, please let us know.

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Keywords: Endogenous adenosines receptor agonists Non-Selective Receptors Non-selective Adenosine

2 Citations for Adenosine

Citations are publications that use Tocris products. Selected citations for Adenosine include:

Hamby et al (2012) Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. PLoS One 32 14489 PMID: 23077035

Bumpus and Johnson (2011) 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated J Neurosci 339 886 PMID: 21896918


Do you know of a great paper that uses Adenosine from Tocris? If so please let us know.

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Reviews

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Literature in this Area

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Pathways for Adenosine

Protocols

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