ACSF

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Cat.No. 3525 - ACSF
Description: Artificial cerebrospinal fluid
Chemical Name: Artificial cerebrospinal fluid
Datasheet
Citations (8)
Literature

Biological Activity

Artificial cerebrospinal fluid (aCSF) commonly used when sampling from brain interstitial fluid. Closely matches the electrolyte concentrations of CSF and is prepared from high purity water and analytical grade reagents. Microfiltered and sterile. Final ion concentrations (in mM): Na 150; K 3.0; Ca 1.4; Mg 0.8; P 1.0; Cl 155.

Technical Data

Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Byun et al (2012) Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease. PLoS One 7 e37917 PMID: 22662249


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Keywords: Artificial cerebrospinal fluid Reagents CSF Biochemicals and Molecular Biology

8 Citations for ACSF

Citations are publications that use Tocris products. Selected citations for ACSF include:

Lam et al (2016) Absence of systemic oxidative stress and increased CSF prostaglandin F2α in progressive MS Neurology: Neuroimmunology & Neuroinflammation 3 256 PMID: 27386506

Rau et al (2015) Increased Basolateral Amygdala Pyramidal Cell Excitability May Contribute to the Anxiogenic Phenotype Induced by Chronic Early-Life Stress. Nat Commun 35 9730 PMID: 26134655

Suberbielle et al (2015) DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice. Front Pharmacol 6 8897 PMID: 26615780

Feetham et al (2015) The depressor response to intracerebroventricular hypotonic saline is sensitive to TRPV4 antagonist RN1734. Electrophoresis 6 83 PMID: 25954200

Taylor et al (2014) Investigating local and long-range neuronal network dynamics by simultaneous optogenetics, reverse microdialysis and silicon probe recordings in vivo. J Neurosci 235 83 PMID: 25004203

McCall et al (2013) Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics. Nat Protoc 8 2413 PMID: 24202555

Handa et al (2013) Central 5-α reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats. J Neurosci Methods 1529 74 PMID: 23880372

Phillips and Wellner (2013) Detection of cerebral spinal fluid-associated chemokines in birth traumatized premature babies by chip-based immunoaffinity CE. J Biol Chem 34 1530 PMID: 23512340


Do you know of a great paper that uses ACSF from Tocris? If so please let us know.

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Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for ACSF

Protocols

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