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Displaying Products by Catalog Number (6300 - 6399)

Cat. No. Product Name / Activity
6300 Thalidomide 4'-oxyacetamide-alkylC4-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
6301 Parathyroid hormone (1-34) (rat)
Parathyroid hormone (PTH) receptor agonist
6302 Pomalidomide
Cereblon binder; also TNF-α inhibitor and antiangiogenic
6304 BigLEN (mouse)
GPR171 agonist
6305 Lenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
6308 PEN (mouse)
GPR83 agonist
6310 AZD 1208
Potent pan Pim kinase inhibitor
6311 Tadalafil
Potent and highly selective PDE5 inhibitor; orally bioavailable
6313 A 33
Potent and selective PDE4B inhibitor
6315 DMNB-caged-Serine
Caged serine; excited by visible blue light
6316 ASB 14780
Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable
6317 Prasugrel
Irreversible P2Y12 antagonist; antiplatelet and orally active
6318 Azimilide dihydrochloride
Kv11.1 (hERG) channel blocker
6319 CBM 301940
Potent malonyl-CoA decarboxylase inhibitor; orally bioavailable
6320 ESI 05
Epac2 inhibitor
6321 10-Cl-BBQ
Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
6322 LW 6
Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α
6323 FX 1
Bcl-6 inhibitor; 10-fold more potent than endogenous Bcl-6 corepressors
6324 Autophinib
Potent VPS34 inhibitor
6327 dBET1
(+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
6329 Clozapine N-oxide dihydrochloride
Activator of hM3Dq and hM4Di DREADDs; water soluble version of Clozapine N-oxide (Cat. No. 4936)
6330 AZ 5704
Potent and selective ATM kinase inhibitor; orally bioavailable
6332 Atosiban
Potent oxytocin receptor antagonist
6333 Phosphoramidon disodium salt
Neutral endopeptidase and endothelin converting enzyme inhibitor
6334 THDOC
Positive modulator of GABAA receptors; endogenous neurosteroid
6336 Trazodone hydrochloride
5-HT2A and α1 adrenoceptor antagonist; also enhances neural differentiation; antidepressant and neuroprotectant
6340 Epiblastin A
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal
6341 INF 39
Irreversible NLRP3 inhibitor
6342 Tamoxifen
Estrogen receptor partial agonist/antagonist
6343 Rosuvastatin calcium
Potent HMG-CoA reductase inhibitor
6344 OUL 35
Selective PARP-10 inhibitor
6346 PF 5006739
Potent CK1δ/ε inhibitor
6347 PF 04628935
Potent ghrelin receptor inverse agonist
6348 PF 06424439
Potent and selective DGAT2 inhibitor
6349 Pelitinib
Potent and irreversible EGFR inhibitor; orally bioavailable
6350 PF 05190457
High affinity and selective ghrelin receptor inverse agonist
6351 (R)-ZINC 3573
MRGPRX2 agonist
6353 UoS 12258
Positive allosteric modulator of AMPA receptors
6354 CNV Dopamine
Caged dopamine; photolysed by UV light
6355 VU 0650991
Non-competitive GLP-1 antagonist; orally bioavailable and brain penetrant
6356 AT 1
(+)-JQ1 based PROTAC® with selectivity for BRD4
6357 Ciclesonide
Glucocorticoid antiasthmatic prodrug
6359 Nelarabine
Purine nuceloside analog; inhibits DNA synthesis
6362 GSK 143
Syk inhibitor
6363 Avagacestat
Highly potent γ-secretase inhibitor; orally bioavailable
6364 Squarunkin A hydrochloride
UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation
6367 Z 944
CaV3.x blocker
6369 GNE 9278
Positive allosteric modulator of NMDA receptors; acts in transmembrane domain
6370 Nor NOHA monoacetate
Arginase inhibitor
6372 PSB CB5
Selective GPR18 antagonist
6373 PF 06650833
Potent and selective IRAK4 inhibitor
6374 PF 04457845
Potent and selective irreversible FAAH inhibitor
6376 DIM-C-pPhOCH3
Nur77 agonist
6377 DIM-C-pPhOH
Nur77 antagonist
6378 JMS 17-2 hydrochloride
CX3CR1 antagonist
6383 SR 16832
Dual site PPARγ inhibitor
6384 Ciclopirox
Pan-histone demethylase inhibitor
6385 Phenanthroline
Enhances hPSC differentiation into cranial placode cells
6387 A 485
Potent and selective p300/CBP inhibitor; orally bioavailable
6389 BAY 677
Inactive control for BAY 678 (Cat.No.5706)
6390 SAG dihydrochloride
Dihydrochloride salt of SAG; Smo receptor agonist
6391 CD38 inhibitor 78c
Potent CD38 inhibitor; active in vivo
6392 B02
RAD51 recombinase inhibitor
6398 SKA 121
Positive allosteric modulator of KCa3.1 (IK) channels

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