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Displaying Products by Catalog Number (4700 - 4799)

Cat. No. Product Name / Activity
4700 PU 02
Negative allosteric modulator of 5-HT3 receptors
4701 EC 144
High affinity, potent and selective Hsp90 inhibitor
4702 ETP 45658
Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
4703 3-Deazaneplanocin A hydrochloride
EZH2 histone methyltransferase inhibitor
4705 Chetomin
Blocks interaction of HIF-1α, HIF-2α and STAT2 with CBP/p300
4706 Borrelidin
Antiangiogenic; inhibits threonyl-tRNA synthetase
4707 MI 2 dihydrochloride
Menin-MLL interaction inhibitor
4708 TC LPA5 4
LPA5 receptor antagonist
4709 RuBi GABA trimethylphosphine
Caged GABA; inhibits neural activity
4710 PF 06465469
Potent ITK inhibitor; also inhibits BTK
4711 Hexa-D-arginine
Furin inhibitor
4712 Salmeterol xinafoate
Long-acting β2 agonist; bronchodilator
4713 IQ 1
Enables Wnt/β-catenin-driven expansion of ESCs; prevents spontaneous differentiation
4715 JZL 195
Dual FAAH and MAGL inhibitor
4716 A 967079
Selective TRPA1 channel blocker
4717 Jervine
Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo
4718 Huwentoxin IV
Selective NaV1.7 channel blocker
4719 VU 0463271
Potent and selective KCC2 inhibitor
4720 Entacapone
Potent COMT inhibitor; blocks α-synuclein aggregation
4722 Decynium 22
PMAT inhibitor
4723 T2AA
PCNA inhibitor
4724 BTT 3033
Selective inhibitor of integrin α2β1
4725 Eptifibatide
Glycoprotein IIb/IIIa inhibitor; inhibits platelet aggregation
4726 CTA 056
ITK inhibitor
4727 GS 6201
Selective A2B antagonist
4729 α-Spinasterol
TRPV1 antagonist; active in vivo
4730 PPY A
Potent inhibitor of Abl T315l mutant and wild-type Abl kinases
4731 KY 02111
Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
4732 ML 204
Selective TRPC4 blocker
4733 P005091
USP7 inhibitor
4734 TRC 051384
Inducer of heat shock protein Hsp70
4735 Quetiapine hemifumarate
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
4736 WIN 18446
ALDH1A2 inhibitor
4737 CDDO Im
Nrf2 signaling activator
4738 LY 333531 hydrochloride
Protein kinase C inhibitor; selective for β isozymes
4739 Cesium chloride
Potassium channel blocker; neuroprotective
4740 Lithium carbonate
Mood stabilizer; inhibits GSK-3 in vivo
4741 Gadolinium chloride
Stretch-activated calcium channel blocker; calcium-sensing receptor agonist
4742 Gue 1654
Selective inhibitor of OXE-R Gβγ signaling
4744 P11
Potent antagonist of αvβ3-vitronectin interaction; antiangiogenic
4745 LIMKi 3
Potent LIM kinase inhibitor; antitumor
4746 ML SA1
Activator of TRPML channels
4747 TC-G 1006
Potent and selective sphingosine-1-phosphate receptor 1 (S1P1) agonist
4748 ML 221
Apelin antagonist
4749 Strontium chloride
Calcium sensing receptor (CaSR) agonist
4750 TC Mps1 12
Potent and selective Mps1 kinase inhibitor
4751 FSLLRY-NH2
PAR2 peptide antagonist
4752 SA 57
Potent FAAH inhibitor
4753 AL 8697
Potent and selective p38α inhibitor
4754 AK 7
Selective SIRT2 inhibitor; brain penetrant
4755 Q94 hydrochloride
Negative allosteric modulator at PAR1 receptor
4756 COR 170
Selective CB2 receptor inverse agonist
4757 Latanoprost
FP prostaglandin receptor agonist; also exhibits agonist activity at EP1 and EP3 receptors
4758 Bromosporine
Broad spectrum bromodomain inhibitor
4759 G-36
Selective GPER antagonist
4761 Plumbagin
Induces G2/M cell cycle arrest; anticancer
4762 MIM1
Mcl-1 inhibitor; proapoptotic
4763 Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
4764 SIB 1553A hydrochloride
nAChR agonist; displays selectivity for β4 subunit-containing receptors
4766 SIB 1508Y maleate
Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors
4767 WAY 316606 hydrochloride
Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling
4769 VUF 10460
Selective H4 agonist
4773 ESI 09
Epac inhibitor
4774 BMS 536924
Dual IR/IGF1R inhibitor
4775 SD 2590 hydrochloride
Potent MMP inhibitor
4776 BIRT 377
Potent negative allosteric modulator of LFA-1
4777 ML 277
Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current
4778 BETP
Positive allosteric modulator of GLP-1 receptors
4779 GRI 977143
Selective LPA2 receptor non-lipid agonist
4780 VUF 11207 fumarate
Potent ACKR3 (CXCR7) agonist
4781 ANA 12
TrkB receptor antagonist
4782 Org 25543 hydrochloride
Potent and selective GlyT2 inhibitor
4784 Edaglitazone
Potent and selective PPARγ agonist; antidiabetic
4785 SA 47
Selective FAAH inhibitor
4786 PD 0332991 isethionate
Potent cdk4 and cdk6 inhibitor; brain penetrant
4787 CPPHA
Positive allosteric modulator of mGlu1 and mGlu5 receptors
4788 NS 11021
Activator of BKCa (KCa1.1) channels
4791 Candesartan
AT1 antagonist
4792 Candesartan cilexetil
Prodrug of candesartan (Cat. No. 4791), an AT1 receptor antagonist
4793 CE3F4
Noncompetitive Epac1 inhibitor
4794 ZCL 278
Cdc42 inhibitor
4795 Galloflavin
Lactate dehydrogenase inhibitor; impairs aerobic glycolysis
4796 Escitalopram oxalate
Selective serotonin reuptake inhibitor (SSRI)
4797 Org 37684
5-HT2 agonist
4798 (S)-Duloxetine hydrochloride
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
4799 Capecitabine
Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis

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