Expertise

The synthetic capability of our chemistry team is vast

We synthesise the majority of the 4000 item catalog range in-house and as a result our chemists are highly experienced in preparing biologically active molecules that are both structurally and synthetically diverse.

Examples from our catalogue to illustrate the diversity of our work

2531 | Ganaxalone

Ganaxalone : Potent positive allosteric modulator of GABAA receptors

Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors.

2476 | SR 11302

SR 11302 : Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumour effects in vivo

Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumour effects in vivo; antitumour agent.

2416 | BIBX 1382

BIBX 1382: Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase

Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.

2592 | TCB-2

TCB-2 : High affinity 5-HT2A receptor agonist. Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2

High affinity 5-HT2A receptor agonist. Potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors.

2453 | LY 379268

LY 379268 : Highly selective group II mGlu receptor agonist that displays > 80-fold selectivity over group I and group III

Highly selective group II mGlu receptor agonist that displays > 80-fold selectivity over group I and group III receptors.

2623 | Oxaliplatin

Oxaliplatin : Antitumour agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA repli

Antitumour agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription.