Glutathione (GSH) precursor and cell permeable antioxidant. Improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances functional recovery following spinal cord injury in rats. Also enhances behavioral recovery in rats following traumatic brain injury. Neuroprotective.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 162.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||6.16 mL||30.82 mL||61.65 mL|
|5 mM||1.23 mL||6.16 mL||12.33 mL|
|10 mM||0.62 mL||3.08 mL||6.16 mL|
|50 mM||0.12 mL||0.62 mL||1.23 mL|
References are publications that support the products' biological activity.
Patel et al (2014) N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma. Exp.Neurol. 257 95 PMID: 24805071
Pandya et al (2014) N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI. Exp.Neurol. 257 106 PMID: 24792639
If you know of a relevant reference for N-Acetylcysteine amide, please let us know.
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Keywords: N-Acetylcysteine amide, supplier, cell, permeable, antioxidant, neuroprotective, glutathione, precursor, GSH, organoids, Antioxidants, Antioxidants, Tocris Bioscience
1 Citation for N-Acetylcysteine amide
Citations are publications that use Tocris products. Selected citations for N-Acetylcysteine amide include:
Gutierrez et al (2014) The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem 289 33568 PMID: 25301941
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