You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Sitagliptin phosphate
Sitagliptin phosphate is a potent and selective DPP IV (DPP4) inhibitor (IC50 = 18 nM). Displays >2600-fold selectivity for DDP IV over other proline specific peptidases. Reduces blood glucose and increases GLP-1 levels after oral glucose tolerance test in normal and diet-induced obese mice.
Compound Libraries for Sitagliptin phosphate
Technical Data for Sitagliptin phosphate
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Sitagliptin phosphate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Sitagliptin phosphate
The following data is based on the product molecular weight 505.31. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||3.96 mL||19.79 mL||39.58 mL|
|2.5 mM||0.79 mL||3.96 mL||7.92 mL|
|5 mM||0.4 mL||1.98 mL||3.96 mL|
|25 mM||0.08 mL||0.4 mL||0.79 mL|
Product Datasheets for Sitagliptin phosphate
References for Sitagliptin phosphate
References are publications that support the biological activity of the product.
Kim et al (2005) (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-α]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J.Med.Chem. 48 141 PMID: 15634008
If you know of a relevant reference for Sitagliptin phosphate, please let us know.
View Related Products by Product Action
Keywords: Sitagliptin phosphate, Sitagliptin phosphate supplier, DPPIV, DPP4, inhibitors, inhibits, potent, selective, CD26, Dipeptidyl, Peptidase, IV, (DPP-IV), 6816, Tocris Bioscience
Citations for Sitagliptin phosphate
Citations are publications that use Tocris products.
Currently there are no citations for Sitagliptin phosphate. Do you know of a great paper that uses Sitagliptin phosphate from Tocris? Please let us know.
Reviews for Sitagliptin phosphate
There are currently no reviews for this product. Be the first to review Sitagliptin phosphate and earn rewards!
Have you used Sitagliptin phosphate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image