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SSM 3 trifluoroacetate
Biological Activity for SSM 3 trifluoroacetate
SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro.
Compound Libraries for SSM 3 trifluoroacetate
Technical Data for SSM 3 trifluoroacetate
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SSM 3 trifluoroacetate
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for SSM 3 trifluoroacetate
The following data is based on the product molecular weight 952.66. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.05 mL||5.25 mL||10.5 mL|
|5 mM||0.21 mL||1.05 mL||2.1 mL|
|10 mM||0.1 mL||0.52 mL||1.05 mL|
|50 mM||0.02 mL||0.1 mL||0.21 mL|
Product Datasheets for SSM 3 trifluoroacetate
References for SSM 3 trifluoroacetate
References are publications that support the biological activity of the product.
Remacle (2010) Selective and potent furin inhibitors protect cells from anthrax without significant toxicity. Int.J.Biochem.Cell Biol. 42 987 PMID: 20197107
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Keywords: SSM 3 trifluoroacetate, SSM 3 trifluoroacetate supplier, SSM3, SSM, 3, trifluoroacetate, furin, inhibitors, inhibits, SSM-3, 922732-52-3, Furin, 5253, Tocris Bioscience
3 Citations for SSM 3 trifluoroacetate
Citations are publications that use Tocris products. Selected citations for SSM 3 trifluoroacetate include:
Rui et al (2021) Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets. J Clin Invest 131 PMID: 34128839
Hervouet et al (2022) An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell. PLoS Pathog. 18 e1010798 PMID: 36007070
Cheng et al (2020) Furin inhibitors block SARS-CoV-2 spike protein cleavage to suppress virus production and cytopathic effects. Cell Rep. 33 PMID: 33007239
Do you know of a great paper that uses SSM 3 trifluoroacetate from Tocris? Please let us know.
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