You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Potent TRPC6 inhibitor (IC50 values are 9.5, 226 and 282 nM for TRPC6, TRPC7 and TRPC3-mediated Ca2+ influx). Exhibits no significant activity at TRPC4 and TRPC5 channels. Suppresses TRPC6-dependent acute hypoxic pulmonary vasoconstriction (HPV) in the isolated perfused mouse lung. Orally bioavailable.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 440.79. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.27 mL||11.34 mL||22.69 mL|
|5 mM||0.45 mL||2.27 mL||4.54 mL|
|10 mM||0.23 mL||1.13 mL||2.27 mL|
|50 mM||0.05 mL||0.23 mL||0.45 mL|
References are publications that support the biological activity of the product.
Maier et al (2015) Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels. Br.J.Pharmacol. 172 3650 PMID: 25847402
If you know of a relevant reference for SAR 7334, please let us know.
View Related Products by Product Action
Keywords: SAR 7334, SAR 7334 supplier, SAR7334, potent, transient, receptor, potential, canonical, channel, TRPC6, inhibitors, inhibits, orally, bioavailable, hypoxic, pulmonary, vasoconstriction, hpv, TRPC, 5831, Tocris Bioscience
Citations for SAR 7334
Citations are publications that use Tocris products.
Currently there are no citations for SAR 7334. Do you know of a great paper that uses SAR 7334 from Tocris? Please let us know.
Reviews for SAR 7334
There are currently no reviews for this product. Be the first to review SAR 7334 and earn rewards!
Have you used SAR 7334?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image