You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for SB 3CT
SB 3CT is a selective high affinity MMP2 inhibitor (Ki = 28 nM); also inhibits MMP9 (Ki = 400 nM). Active in vivo, neuroprotective and blood-brain barrier permeable.
Technical Data for SB 3CT
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for SB 3CT
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for SB 3CT
The following data is based on the product molecular weight 306.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.26 mL||16.32 mL||32.64 mL|
|5 mM||0.65 mL||3.26 mL||6.53 mL|
|10 mM||0.33 mL||1.63 mL||3.26 mL|
|50 mM||0.07 mL||0.33 mL||0.65 mL|
References for SB 3CT
References are publications that support the biological activity of the product.
Gu et al (2005) A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. J.Neurosci. 25 6401 PMID: 16000631
Kleifeld et al (2001) X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. comparison with the latent and active forms of the enzyme. J.Biol.Chem. 18 17125 PMID: 11278946
Gooyit et al (2012) Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier. ACS Chem.Neurosci. 3 730 PMID: 23077716
If you know of a relevant reference for SB 3CT, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: SB 3CT, SB 3CT supplier, SB3CT, Selective, high, affinity, MMP2, inhibitors, MMP9, blood-brain, barrier, BBB, permeable, matrix, metalloproteinases, neuroprotective, Matrix, Metalloprotease, 6088, Tocris Bioscience
Citations for SB 3CT
Citations are publications that use Tocris products.
Currently there are no citations for SB 3CT. Do you know of a great paper that uses SB 3CT from Tocris? Please let us know.
Reviews for SB 3CT
There are currently no reviews for this product. Be the first to review SB 3CT and earn rewards!
Have you used SB 3CT?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.