SCOTfluor 510, fluoro

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Description: Amine-reactive fluorescent probe precursor
Chemical Name: 4-Fluoro-7-nitro-2,1,3-benzoselenadiazole
Purity: ≥90% (HPLC)
Literature (1)

Biological Activity for SCOTfluor 510, fluoro

SCOTfluor 510, fluoro is a precursor that, upon reaction with amine groups, can be used for the synthesis of fluorescent probes. Can be used to generate functionalized lactic acid, glucose and ceramide fluorescent probes for real-time, in situ imaging of small molecule metabolites in vivo and in live cells. Fluorescent adduct excitation maximum = 510 nm; emission maximum = 606 nm.

Licensing Information

Sold under license from the University of Edinburgh

Usage Guidelines for SCOTfluor 510, fluoro

This product is provided for use in onward chemistry. Suitable solvents can be used.

Optical Data for SCOTfluor 510, fluoro

Emission Color Orange
λabs 510 nm
λem 606 nm
Extinction Coefficient (ε) 16300 M-1cm-1
Quantum Yield (φ) 0.2
Closest Laser line 488 nm
Reactivity Primary amines
Cell Permeable Yes
Application Conjugation to Primary Amines, in vivo Imaging

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Technical Data for SCOTfluor 510, fluoro

M. Wt 246.06
Formula C6H2FN3O2Se
Storage Store at -20°C
Purity ≥90% (HPLC)
CAS Number 2351940-09-3
PubChem ID 155694544
Smiles FC1=CC=C(N(=O)=O)C2=N[Se]N=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for SCOTfluor 510, fluoro

References for SCOTfluor 510, fluoro

References are publications that support the biological activity of the product.

Benson et al (2019) SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism. Angew.Chem.Int.Ed.Engl. 58 6911 PMID: 30924239

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Citations for SCOTfluor 510, fluoro

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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