Sodium Cromoglicate

Pricing Availability   Qty
Description: Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
Chemical Name: 5,5'-[(2-Hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo-4H-1-benzopyran-2-carboxylic acid] disodium salt
Purity: ≥98% (HPLC)
Literature (4)

Biological Activity for Sodium Cromoglicate

Sodium Cromoglicate is a promotes transformation ESCs/iPSCs into pancreatic endocrine islet cells. Facilitates differentiation from endocrine precursors. Also inhibits mast cell degranulation and histamine release. Antiasthmatic.

Technical Data for Sodium Cromoglicate

M. Wt 512.33
Formula C23H14Na2O11
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 15826-37-6
PubChem ID 27503
Smiles OC(COC1=C2C(C=C(C(O[Na])=O)OC2=CC=C1)=O)COC3=C4C(C=C(C(O[Na])=O)OC4=CC=C3)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Sodium Cromoglicate

Solvent Max Conc. mg/mL Max Conc. mM
water 25.62 50

Preparing Stock Solutions for Sodium Cromoglicate

The following data is based on the product molecular weight 512.33. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.9 mL 19.52 mL 39.04 mL
2.5 mM 0.78 mL 3.9 mL 7.81 mL
5 mM 0.39 mL 1.95 mL 3.9 mL
25 mM 0.08 mL 0.39 mL 0.78 mL

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Product Datasheets for Sodium Cromoglicate

References for Sodium Cromoglicate

References are publications that support the biological activity of the product.

Orr and Cox (1969) Disodium Cromoglycate, an inhibitor of mast cell degranulation and histamine release induced by phospholipase A. Nature. 223 197 PMID: 4183038

Kondo et al (2017) Identification of a small molecule that facilitates the differentiation of human iPSCS/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells. Diabetologia. 60 1454 PMID: 28534195

If you know of a relevant reference for Sodium Cromoglicate, please let us know.

Keywords: Sodium Cromoglicate, Sodium Cromoglicate supplier, sodium, cromoglicate, cromoglycate, differentiation, pancreatic, islet, cells, mast, cell, degranulation, histamine, anti-asthmatic, ESCs, and, iPSC, Histaminergic-Related, Compounds, 6424, Tocris Bioscience

Citations for Sodium Cromoglicate

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Currently there are no citations for Sodium Cromoglicate. Do you know of a great paper that uses Sodium Cromoglicate from Tocris? Please let us know.

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