Secretin (human)

Pricing Availability   Qty
Cat.No. 1918 - Secretin (human) | His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 | CAS No. 108153-74-8
Description: Gastrointestinal peptide
Datasheet
Citations (1)
Reviews
Literature

Biological Activity

Gastrointestinal peptide that stimulates pancreatic and biliary secretion. Also thought to play a role in the regulation of the hypothalamus-pituitary-adrenal axis.

Secretin (rat) also available.

Technical Data

M. Wt 3039.44
Formula C130H220N44O40
Sequence HSDGTFTSELSRLREGARLQRLLQGLV

(Modifications: Val-27 = C-terminal amide)

Storage Desiccate at -20°C
CAS Number 108153-74-8
PubChem ID 16158474
InChI Key OWMZNFCDEHGFEP-NFBCVYDUSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Nussdorfer et al (2000) Secretin, glucagon, gastric inhibitor polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus-pituitary-adrenal axis. Peptides 21 309 PMID: 10764961

Sherwood et al (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/Glucagon superfamily. Endocr.Rev. 21 619 PMID: 11133067


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Keywords: Secretin (human), Secretin (human) supplier, Gastrointestinal, peptide, Secretin, Receptors, Glucagon, 1918, Tocris Bioscience

1 Citation for Secretin (human)

Citations are publications that use Tocris products. Selected citations for Secretin (human) include:

Lee et al (2012) Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Mol Endocrinol 26 1394 PMID: 22692904


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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